Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8907
Gene name Gene Name - the full gene name approved by the HGNC.
Adaptor related protein complex 1 subunit mu 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
AP1M1
Synonyms (NCBI Gene) Gene synonyms aliases
AP47, CLAPM2, CLTNM, MU-1A, mu1A
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19p13.11
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT023891 hsa-miR-1-3p Proteomics 18668040
MIRT025884 hsa-miR-7-5p Microarray 19073608
MIRT025884 hsa-miR-7-5p Sequencing 20371350
MIRT047323 hsa-miR-181a-5p CLASH 23622248
MIRT036991 hsa-miR-877-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane TAS
GO:0005515 Function Protein binding IPI 14691137, 16189514, 19060904, 25416956, 28514442, 32296183
GO:0005765 Component Lysosomal membrane TAS
GO:0005829 Component Cytosol TAS
GO:0005886 Component Plasma membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603535 13667 ENSG00000072958
Protein
UniProt ID Q9BXS5
Protein name AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathr
Protein function Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signal
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01217 Clat_adaptor_s 2 141 Clathrin adaptor complex small chain Domain
PF00928 Adap_comp_sub 157 422 Adaptor complexes medium subunit family Family
Sequence
Sequence length 423
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Lysosome
Human immunodeficiency virus 1 infection
  Nef mediated downregulation of MHC class I complex cell surface expression
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Neutrophil degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
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