DDX18 (DEAD-box helicase 18)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 8886 |
| Gene name | DEAD-box helicase 18 |
| Gene symbol | DDX18 |
| Synonyms (NCBI Gene) |
Has1MrDb
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| Chromosome | 2 |
| Chromosome location | 2q14.1 |
| Summary | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and m |
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miRNA
miRNA information provided by mirtarbase database.
409
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
1
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NVP1 | ||||||||||||||||||||
| Protein name | ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb) | ||||||||||||||||||||
| Protein function | ATP-dependent RNA helicase that plays a role in the regulation of R-loop homeostasis in both endogenous R-loop-prone regions and at sites of DNA damage. At endogenous loci such as actively transcribed genes, may act as a helicase to resolve the | ||||||||||||||||||||
| PDB | 3LY5 , 8FKP , 8FKQ , 8FKR , 8FKS , 8FKT , 8FKU , 8FKV , 8FKW , 8FKX , 8FKY | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 670 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||