Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8851
Gene name Gene Name - the full gene name approved by the HGNC.	Cyclin dependent kinase 5 regulatory subunit 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CDK5R1
Synonyms (NCBI Gene) Gene synonyms aliases	CDK5P35, CDK5R, NCK5A, p23, p25, p35, p35nck5a
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q11.2
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by

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miRTarBase ID	miRNA	Experiments	Reference
MIRT029817	hsa-miR-26b-5p	Microarray	19088304
MIRT042678	hsa-miR-196b-5p	CLASH	23622248
MIRT054108	hsa-miR-1207-5p	Microarray	22995316
MIRT250939	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT250944	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT250941	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT250940	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT250943	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT250942	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT286706	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT250951	hsa-miR-548ac	PAR-CLIP	20371350
MIRT250954	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT250945	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT250946	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT250949	hsa-miR-548z	PAR-CLIP	20371350
MIRT250950	hsa-miR-548aa	PAR-CLIP	20371350
MIRT250952	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT250947	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT286719	hsa-miR-6507-5p	PAR-CLIP	20371350
MIRT250948	hsa-miR-548v	PAR-CLIP	20371350
MIRT548927	hsa-miR-7703	PAR-CLIP	20371350
MIRT548926	hsa-miR-4325	PAR-CLIP	20371350
MIRT250939	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT250944	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT250941	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT250940	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT250943	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT250942	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT286706	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT250951	hsa-miR-548ac	PAR-CLIP	20371350
MIRT250954	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT250945	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT250946	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT250949	hsa-miR-548z	PAR-CLIP	20371350
MIRT250950	hsa-miR-548aa	PAR-CLIP	20371350
MIRT250952	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT250947	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT286719	hsa-miR-6507-5p	PAR-CLIP	20371350
MIRT250948	hsa-miR-548v	PAR-CLIP	20371350
MIRT548927	hsa-miR-7703	PAR-CLIP	20371350
MIRT548926	hsa-miR-4325	PAR-CLIP	20371350
MIRT286706	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT250939	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT250944	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT250941	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT250940	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT250943	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT250942	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT558811	hsa-miR-133b	PAR-CLIP	21572407
MIRT558810	hsa-miR-133a-3p	PAR-CLIP	21572407
MIRT250951	hsa-miR-548ac	PAR-CLIP	21572407
MIRT250954	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT250945	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT250946	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT250949	hsa-miR-548z	PAR-CLIP	21572407
MIRT250950	hsa-miR-548aa	PAR-CLIP	21572407
MIRT250952	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT250947	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT286719	hsa-miR-6507-5p	PAR-CLIP	21572407
MIRT250948	hsa-miR-548v	PAR-CLIP	21572407
MIRT548927	hsa-miR-7703	PAR-CLIP	21572407
MIRT548926	hsa-miR-4325	PAR-CLIP	21572407
MIRT558809	hsa-miR-5587-5p	PAR-CLIP	21572407
MIRT250939	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT250944	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT250941	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT250940	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT250943	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT250942	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT250951	hsa-miR-548ac	PAR-CLIP	21572407
MIRT250954	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT250945	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT250946	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT250949	hsa-miR-548z	PAR-CLIP	21572407
MIRT250950	hsa-miR-548aa	PAR-CLIP	21572407
MIRT250952	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT250947	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT250948	hsa-miR-548v	PAR-CLIP	21572407
MIRT548927	hsa-miR-7703	PAR-CLIP	21572407
MIRT548926	hsa-miR-4325	PAR-CLIP	21572407
MIRT250939	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT250944	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT250941	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT250940	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT250943	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT250942	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT286706	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT250951	hsa-miR-548ac	PAR-CLIP	20371350
MIRT250954	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT250945	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT250946	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT250949	hsa-miR-548z	PAR-CLIP	20371350
MIRT250950	hsa-miR-548aa	PAR-CLIP	20371350
MIRT250952	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT250947	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT286719	hsa-miR-6507-5p	PAR-CLIP	20371350
MIRT250948	hsa-miR-548v	PAR-CLIP	20371350
MIRT548927	hsa-miR-7703	PAR-CLIP	20371350
MIRT548926	hsa-miR-4325	PAR-CLIP	20371350
MIRT250939	hsa-miR-25-3p	PAR-CLIP	20371350
MIRT250944	hsa-miR-92b-3p	PAR-CLIP	20371350
MIRT250941	hsa-miR-92a-3p	PAR-CLIP	20371350
MIRT250940	hsa-miR-32-5p	PAR-CLIP	20371350
MIRT250943	hsa-miR-367-3p	PAR-CLIP	20371350
MIRT250942	hsa-miR-363-3p	PAR-CLIP	20371350
MIRT286706	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT250951	hsa-miR-548ac	PAR-CLIP	20371350
MIRT250954	hsa-miR-548bb-3p	PAR-CLIP	20371350
MIRT250945	hsa-miR-548d-3p	PAR-CLIP	20371350
MIRT250946	hsa-miR-548h-3p	PAR-CLIP	20371350
MIRT250949	hsa-miR-548z	PAR-CLIP	20371350
MIRT250950	hsa-miR-548aa	PAR-CLIP	20371350
MIRT250952	hsa-miR-548ap-3p	PAR-CLIP	20371350
MIRT250947	hsa-miR-548t-3p	PAR-CLIP	20371350
MIRT286719	hsa-miR-6507-5p	PAR-CLIP	20371350
MIRT250948	hsa-miR-548v	PAR-CLIP	20371350
MIRT548927	hsa-miR-7703	PAR-CLIP	20371350
MIRT548926	hsa-miR-4325	PAR-CLIP	20371350
MIRT286706	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT250939	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT250944	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT250941	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT250940	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT250943	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT250942	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT558811	hsa-miR-133b	PAR-CLIP	21572407
MIRT558810	hsa-miR-133a-3p	PAR-CLIP	21572407
MIRT250951	hsa-miR-548ac	PAR-CLIP	21572407
MIRT250954	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT250945	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT250946	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT250949	hsa-miR-548z	PAR-CLIP	21572407
MIRT250950	hsa-miR-548aa	PAR-CLIP	21572407
MIRT250952	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT250947	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT286719	hsa-miR-6507-5p	PAR-CLIP	21572407
MIRT250948	hsa-miR-548v	PAR-CLIP	21572407
MIRT548927	hsa-miR-7703	PAR-CLIP	21572407
MIRT548926	hsa-miR-4325	PAR-CLIP	21572407
MIRT558809	hsa-miR-5587-5p	PAR-CLIP	21572407
MIRT250939	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT250944	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT250941	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT250940	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT250943	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT250942	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT250951	hsa-miR-548ac	PAR-CLIP	21572407
MIRT250954	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT250945	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT250946	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT250949	hsa-miR-548z	PAR-CLIP	21572407
MIRT250950	hsa-miR-548aa	PAR-CLIP	21572407
MIRT250952	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT250947	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT250948	hsa-miR-548v	PAR-CLIP	21572407
MIRT548927	hsa-miR-7703	PAR-CLIP	21572407
MIRT548926	hsa-miR-4325	PAR-CLIP	21572407
MIRT756258	hsa-miR-148a-3p	Luciferase reporter assay, Western blotting, qRT-PCR	35024240
MIRT881192	hsa-miR-103a	CLIP-seq
MIRT881193	hsa-miR-103b	CLIP-seq
MIRT881194	hsa-miR-107	CLIP-seq
MIRT881195	hsa-miR-1224-3p	CLIP-seq
MIRT881196	hsa-miR-1236	CLIP-seq
MIRT881197	hsa-miR-1254	CLIP-seq
MIRT881198	hsa-miR-1273e	CLIP-seq
MIRT881199	hsa-miR-1297	CLIP-seq
MIRT881200	hsa-miR-1302	CLIP-seq
MIRT881201	hsa-miR-130a	CLIP-seq
MIRT881202	hsa-miR-130b	CLIP-seq
MIRT881203	hsa-miR-148a	CLIP-seq
MIRT881204	hsa-miR-148b	CLIP-seq
MIRT881205	hsa-miR-152	CLIP-seq
MIRT881206	hsa-miR-15a	CLIP-seq
MIRT881207	hsa-miR-15b	CLIP-seq
MIRT881208	hsa-miR-16	CLIP-seq
MIRT881209	hsa-miR-1825	CLIP-seq
MIRT881210	hsa-miR-185	CLIP-seq
MIRT881211	hsa-miR-195	CLIP-seq
MIRT881212	hsa-miR-199a-3p	CLIP-seq
MIRT881213	hsa-miR-199b-3p	CLIP-seq
MIRT881214	hsa-miR-200b	CLIP-seq
MIRT881215	hsa-miR-200c	CLIP-seq
MIRT881216	hsa-miR-2113	CLIP-seq
MIRT881217	hsa-miR-2355-5p	CLIP-seq
MIRT881218	hsa-miR-26a	CLIP-seq
MIRT881219	hsa-miR-26b	CLIP-seq
MIRT881220	hsa-miR-27a	CLIP-seq
MIRT881221	hsa-miR-27b	CLIP-seq
MIRT881222	hsa-miR-2861	CLIP-seq
MIRT881223	hsa-miR-301a	CLIP-seq
MIRT881224	hsa-miR-301b	CLIP-seq
MIRT881225	hsa-miR-3074-3p	CLIP-seq
MIRT881226	hsa-miR-3116	CLIP-seq
MIRT881227	hsa-miR-3122	CLIP-seq
MIRT881228	hsa-miR-3129-5p	CLIP-seq
MIRT881229	hsa-miR-3155	CLIP-seq
MIRT881230	hsa-miR-3155b	CLIP-seq
MIRT881231	hsa-miR-3160-5p	CLIP-seq
MIRT881232	hsa-miR-3175	CLIP-seq
MIRT881233	hsa-miR-3192	CLIP-seq
MIRT881234	hsa-miR-3199	CLIP-seq
MIRT881235	hsa-miR-323-3p	CLIP-seq
MIRT881236	hsa-miR-323b-3p	CLIP-seq
MIRT881237	hsa-miR-326	CLIP-seq
MIRT881238	hsa-miR-330-5p	CLIP-seq
MIRT881239	hsa-miR-338-5p	CLIP-seq
MIRT881240	hsa-miR-340	CLIP-seq
MIRT881241	hsa-miR-3666	CLIP-seq
MIRT881242	hsa-miR-376a	CLIP-seq
MIRT881243	hsa-miR-376b	CLIP-seq
MIRT881244	hsa-miR-377	CLIP-seq
MIRT881245	hsa-miR-3913-5p	CLIP-seq
MIRT881246	hsa-miR-3925-5p	CLIP-seq
MIRT881247	hsa-miR-3941	CLIP-seq
MIRT881248	hsa-miR-424	CLIP-seq
MIRT881249	hsa-miR-4268	CLIP-seq
MIRT881250	hsa-miR-4272	CLIP-seq
MIRT881251	hsa-miR-4286	CLIP-seq
MIRT881252	hsa-miR-429	CLIP-seq
MIRT881253	hsa-miR-4295	CLIP-seq
MIRT881254	hsa-miR-4298	CLIP-seq
MIRT881255	hsa-miR-4306	CLIP-seq
MIRT881256	hsa-miR-4314	CLIP-seq
MIRT881257	hsa-miR-4326	CLIP-seq
MIRT881258	hsa-miR-4327	CLIP-seq
MIRT881259	hsa-miR-433	CLIP-seq
MIRT881260	hsa-miR-4438	CLIP-seq
MIRT881261	hsa-miR-4448	CLIP-seq
MIRT881262	hsa-miR-4465	CLIP-seq
MIRT881263	hsa-miR-4470	CLIP-seq
MIRT881264	hsa-miR-4502	CLIP-seq
MIRT881265	hsa-miR-4506	CLIP-seq
MIRT881266	hsa-miR-4515	CLIP-seq
MIRT881267	hsa-miR-4524	CLIP-seq
MIRT881268	hsa-miR-454	CLIP-seq
MIRT881269	hsa-miR-4644	CLIP-seq
MIRT881270	hsa-miR-4646-5p	CLIP-seq
MIRT881271	hsa-miR-466	CLIP-seq
MIRT881272	hsa-miR-4671-3p	CLIP-seq
MIRT881273	hsa-miR-4672	CLIP-seq
MIRT881274	hsa-miR-4708-3p	CLIP-seq
MIRT881275	hsa-miR-4731-3p	CLIP-seq
MIRT881276	hsa-miR-4801	CLIP-seq
MIRT881277	hsa-miR-484	CLIP-seq
MIRT881278	hsa-miR-497	CLIP-seq
MIRT881279	hsa-miR-503	CLIP-seq
MIRT881280	hsa-miR-513a-3p	CLIP-seq
MIRT881281	hsa-miR-513a-5p	CLIP-seq
MIRT881282	hsa-miR-548ae	CLIP-seq
MIRT881283	hsa-miR-548aj	CLIP-seq
MIRT881284	hsa-miR-548am	CLIP-seq
MIRT881285	hsa-miR-548n	CLIP-seq
MIRT881286	hsa-miR-548t	CLIP-seq
MIRT881287	hsa-miR-548x	CLIP-seq
MIRT881288	hsa-miR-599	CLIP-seq
MIRT881289	hsa-miR-646	CLIP-seq
MIRT881290	hsa-miR-653	CLIP-seq
MIRT881291	hsa-miR-7	CLIP-seq
MIRT881292	hsa-miR-936	CLIP-seq
MIRT1961017	hsa-miR-101	CLIP-seq
MIRT881192	hsa-miR-103a	CLIP-seq
MIRT881193	hsa-miR-103b	CLIP-seq
MIRT881194	hsa-miR-107	CLIP-seq
MIRT881206	hsa-miR-15a	CLIP-seq
MIRT881207	hsa-miR-15b	CLIP-seq
MIRT881208	hsa-miR-16	CLIP-seq
MIRT881211	hsa-miR-195	CLIP-seq
MIRT1961018	hsa-miR-197	CLIP-seq
MIRT1961019	hsa-miR-214	CLIP-seq
MIRT881225	hsa-miR-3074-3p	CLIP-seq
MIRT1961020	hsa-miR-361-3p	CLIP-seq
MIRT1961021	hsa-miR-3619-5p	CLIP-seq
MIRT1961022	hsa-miR-3679-3p	CLIP-seq
MIRT881242	hsa-miR-376a	CLIP-seq
MIRT881243	hsa-miR-376b	CLIP-seq
MIRT881248	hsa-miR-424	CLIP-seq
MIRT1961023	hsa-miR-4291	CLIP-seq
MIRT881263	hsa-miR-4470	CLIP-seq
MIRT881265	hsa-miR-4506	CLIP-seq
MIRT881267	hsa-miR-4524	CLIP-seq
MIRT1961024	hsa-miR-4690-5p	CLIP-seq
MIRT1961025	hsa-miR-4736	CLIP-seq
MIRT1961026	hsa-miR-4763-3p	CLIP-seq
MIRT881278	hsa-miR-497	CLIP-seq
MIRT881279	hsa-miR-503	CLIP-seq
MIRT881285	hsa-miR-548n	CLIP-seq
MIRT881286	hsa-miR-548t	CLIP-seq
MIRT881289	hsa-miR-646	CLIP-seq
MIRT881290	hsa-miR-653	CLIP-seq
MIRT1961027	hsa-miR-761	CLIP-seq
MIRT1961028	hsa-miR-922	CLIP-seq
MIRT881192	hsa-miR-103a	CLIP-seq
MIRT881193	hsa-miR-103b	CLIP-seq
MIRT881194	hsa-miR-107	CLIP-seq
MIRT881195	hsa-miR-1224-3p	CLIP-seq
MIRT881196	hsa-miR-1236	CLIP-seq
MIRT881198	hsa-miR-1273e	CLIP-seq
MIRT2197754	hsa-miR-1293	CLIP-seq
MIRT881199	hsa-miR-1297	CLIP-seq
MIRT881201	hsa-miR-130a	CLIP-seq
MIRT881202	hsa-miR-130b	CLIP-seq
MIRT881203	hsa-miR-148a	CLIP-seq
MIRT881204	hsa-miR-148b	CLIP-seq
MIRT881205	hsa-miR-152	CLIP-seq
MIRT881206	hsa-miR-15a	CLIP-seq
MIRT881207	hsa-miR-15b	CLIP-seq
MIRT881208	hsa-miR-16	CLIP-seq
MIRT881209	hsa-miR-1825	CLIP-seq
MIRT881210	hsa-miR-185	CLIP-seq
MIRT881211	hsa-miR-195	CLIP-seq
MIRT881214	hsa-miR-200b	CLIP-seq
MIRT881215	hsa-miR-200c	CLIP-seq
MIRT2197755	hsa-miR-2117	CLIP-seq
MIRT881217	hsa-miR-2355-5p	CLIP-seq
MIRT881218	hsa-miR-26a	CLIP-seq
MIRT881219	hsa-miR-26b	CLIP-seq
MIRT881220	hsa-miR-27a	CLIP-seq
MIRT881221	hsa-miR-27b	CLIP-seq
MIRT881222	hsa-miR-2861	CLIP-seq
MIRT881223	hsa-miR-301a	CLIP-seq
MIRT881224	hsa-miR-301b	CLIP-seq
MIRT881225	hsa-miR-3074-3p	CLIP-seq
MIRT881229	hsa-miR-3155	CLIP-seq
MIRT881230	hsa-miR-3155b	CLIP-seq
MIRT2197756	hsa-miR-3166	CLIP-seq
MIRT881232	hsa-miR-3175	CLIP-seq
MIRT881233	hsa-miR-3192	CLIP-seq
MIRT881237	hsa-miR-326	CLIP-seq
MIRT881238	hsa-miR-330-5p	CLIP-seq
MIRT881239	hsa-miR-338-5p	CLIP-seq
MIRT881240	hsa-miR-340	CLIP-seq
MIRT2197757	hsa-miR-3652	CLIP-seq
MIRT881241	hsa-miR-3666	CLIP-seq
MIRT2197758	hsa-miR-3677-5p	CLIP-seq
MIRT2197759	hsa-miR-3680	CLIP-seq
MIRT881242	hsa-miR-376a	CLIP-seq
MIRT881243	hsa-miR-376b	CLIP-seq
MIRT881244	hsa-miR-377	CLIP-seq
MIRT881246	hsa-miR-3925-5p	CLIP-seq
MIRT881247	hsa-miR-3941	CLIP-seq
MIRT881248	hsa-miR-424	CLIP-seq
MIRT2197760	hsa-miR-4261	CLIP-seq
MIRT2197761	hsa-miR-4273	CLIP-seq
MIRT881251	hsa-miR-4286	CLIP-seq
MIRT881252	hsa-miR-429	CLIP-seq
MIRT881253	hsa-miR-4295	CLIP-seq
MIRT2197762	hsa-miR-4300	CLIP-seq
MIRT881255	hsa-miR-4306	CLIP-seq
MIRT881256	hsa-miR-4314	CLIP-seq
MIRT881257	hsa-miR-4326	CLIP-seq
MIRT881258	hsa-miR-4327	CLIP-seq
MIRT881259	hsa-miR-433	CLIP-seq
MIRT2197763	hsa-miR-4427	CLIP-seq
MIRT2197764	hsa-miR-4430	CLIP-seq
MIRT881260	hsa-miR-4438	CLIP-seq
MIRT881261	hsa-miR-4448	CLIP-seq
MIRT881262	hsa-miR-4465	CLIP-seq
MIRT881263	hsa-miR-4470	CLIP-seq
MIRT2197765	hsa-miR-4483	CLIP-seq
MIRT881264	hsa-miR-4502	CLIP-seq
MIRT2197766	hsa-miR-4505	CLIP-seq
MIRT881265	hsa-miR-4506	CLIP-seq
MIRT881267	hsa-miR-4524	CLIP-seq
MIRT2197767	hsa-miR-4530	CLIP-seq
MIRT881268	hsa-miR-454	CLIP-seq
MIRT2197768	hsa-miR-4643	CLIP-seq
MIRT881269	hsa-miR-4644	CLIP-seq
MIRT881270	hsa-miR-4646-5p	CLIP-seq
MIRT881271	hsa-miR-466	CLIP-seq
MIRT881273	hsa-miR-4672	CLIP-seq
MIRT2197769	hsa-miR-4680-3p	CLIP-seq
MIRT881274	hsa-miR-4708-3p	CLIP-seq
MIRT2197770	hsa-miR-4719	CLIP-seq
MIRT881275	hsa-miR-4731-3p	CLIP-seq
MIRT2197771	hsa-miR-4789-3p	CLIP-seq
MIRT2197772	hsa-miR-4798-3p	CLIP-seq
MIRT881276	hsa-miR-4801	CLIP-seq
MIRT881277	hsa-miR-484	CLIP-seq
MIRT881278	hsa-miR-497	CLIP-seq
MIRT881279	hsa-miR-503	CLIP-seq
MIRT881281	hsa-miR-513a-5p	CLIP-seq
MIRT881285	hsa-miR-548n	CLIP-seq
MIRT881286	hsa-miR-548t	CLIP-seq
MIRT2197773	hsa-miR-603	CLIP-seq
MIRT881289	hsa-miR-646	CLIP-seq
MIRT2197774	hsa-miR-661	CLIP-seq
MIRT2197775	hsa-miR-760	CLIP-seq
MIRT2197776	hsa-miR-891a	CLIP-seq
MIRT2197777	hsa-miR-920	CLIP-seq
MIRT1961028	hsa-miR-922	CLIP-seq
MIRT881198	hsa-miR-1273e	CLIP-seq
MIRT881199	hsa-miR-1297	CLIP-seq
MIRT881203	hsa-miR-148a	CLIP-seq
MIRT881204	hsa-miR-148b	CLIP-seq
MIRT881205	hsa-miR-152	CLIP-seq
MIRT881218	hsa-miR-26a	CLIP-seq
MIRT881219	hsa-miR-26b	CLIP-seq
MIRT881225	hsa-miR-3074-3p	CLIP-seq
MIRT881258	hsa-miR-4327	CLIP-seq
MIRT881262	hsa-miR-4465	CLIP-seq
MIRT881263	hsa-miR-4470	CLIP-seq
MIRT881265	hsa-miR-4506	CLIP-seq
MIRT881236	hsa-miR-323b-3p	CLIP-seq
MIRT2446699	hsa-miR-4292	CLIP-seq
MIRT2446700	hsa-miR-4308	CLIP-seq
MIRT2446701	hsa-miR-4514	CLIP-seq
MIRT2446702	hsa-miR-4640-5p	CLIP-seq
MIRT2446703	hsa-miR-4645-5p	CLIP-seq
MIRT2446704	hsa-miR-4673	CLIP-seq
MIRT2446705	hsa-miR-4692	CLIP-seq
MIRT2446706	hsa-miR-4726-5p	CLIP-seq
MIRT2446707	hsa-miR-4749-3p	CLIP-seq
MIRT2446708	hsa-miR-4755-3p	CLIP-seq
MIRT881236	hsa-miR-323b-3p	CLIP-seq
MIRT881195	hsa-miR-1224-3p	CLIP-seq
MIRT881196	hsa-miR-1236	CLIP-seq
MIRT2501037	hsa-miR-1260	CLIP-seq
MIRT2501038	hsa-miR-1260b	CLIP-seq
MIRT2501039	hsa-miR-1280	CLIP-seq
MIRT2501040	hsa-miR-1323	CLIP-seq
MIRT2501041	hsa-miR-186	CLIP-seq
MIRT2501042	hsa-miR-217	CLIP-seq
MIRT881225	hsa-miR-3074-3p	CLIP-seq
MIRT2501043	hsa-miR-3688-3p	CLIP-seq
MIRT2501044	hsa-miR-3978	CLIP-seq
MIRT2501045	hsa-miR-4317	CLIP-seq
MIRT2501046	hsa-miR-4469	CLIP-seq
MIRT2501047	hsa-miR-4715-3p	CLIP-seq
MIRT2501048	hsa-miR-4725-5p	CLIP-seq
MIRT2501049	hsa-miR-4733-3p	CLIP-seq
MIRT2501050	hsa-miR-504	CLIP-seq
MIRT2501051	hsa-miR-532-3p	CLIP-seq
MIRT2501052	hsa-miR-548o	CLIP-seq
MIRT2501053	hsa-miR-642a	CLIP-seq

Transcription factors

Show/Hide all(2)

Transcription factor	Regulation	Reference
EGR1	Activation	15289351
JUN	Unknown	22550165

Show/Hide all(96)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000079	Process	Regulation of cyclin-dependent protein serine/threonine kinase activity	TAS	7592934
GO:0000226	Process	Microtubule cytoskeleton organization	TAS	17491008
GO:0000307	Component	Cyclin-dependent protein kinase holoenzyme complex	IPI	16039528
GO:0001764	Process	Neuron migration	IEA
GO:0001764	Process	Neuron migration	ISS
GO:0002020	Function	Protease binding	IEA
GO:0003779	Function	Actin binding	IEA
GO:0004672	Function	Protein kinase activity	TAS	7592934
GO:0005509	Function	Calcium ion binding	ISS
GO:0005515	Function	Protein binding	IPI	8090221, 10721722, 12223541, 14521924, 15689152, 20133653, 21220307, 23543736, 23602568, 25416956, 28514442, 32814053, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007158	Process	Neuron cell-cell adhesion	IEA
GO:0007158	Process	Neuron cell-cell adhesion	ISS
GO:0007213	Process	G protein-coupled acetylcholine receptor signaling pathway	ISS
GO:0007411	Process	Axon guidance	IBA
GO:0007411	Process	Axon guidance	IEA
GO:0007411	Process	Axon guidance	ISS
GO:0007413	Process	Axonal fasciculation	IEA
GO:0007413	Process	Axonal fasciculation	ISS
GO:0007420	Process	Brain development	IBA
GO:0007420	Process	Brain development	IEA
GO:0007420	Process	Brain development	ISS
GO:0007420	Process	Brain development	NAS	10915792
GO:0014069	Component	Postsynaptic density	ISS
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0016241	Process	Regulation of macroautophagy	NAS	21499257
GO:0016301	Function	Kinase activity	ISS
GO:0016533	Component	Protein kinase 5 complex	IEA
GO:0016533	Component	Protein kinase 5 complex	IPI	15689152
GO:0018105	Process	Peptidyl-serine phosphorylation	IDA	12832520
GO:0018107	Process	Peptidyl-threonine phosphorylation	IDA	12832520
GO:0019901	Function	Protein kinase binding	IBA
GO:0019901	Function	Protein kinase binding	IEA
GO:0019901	Function	Protein kinase binding	IPI	12832520
GO:0021549	Process	Cerebellum development	IEA
GO:0021722	Process	Superior olivary nucleus maturation	IEA
GO:0021766	Process	Hippocampus development	IEA
GO:0021799	Process	Cerebral cortex radially oriented cell migration	IEA
GO:0021819	Process	Layer formation in cerebral cortex	IEA
GO:0030182	Process	Neuron differentiation	ISS
GO:0030295	Function	Protein kinase activator activity	TAS	8090221
GO:0030424	Component	Axon	ISS
GO:0030425	Component	Dendrite	ISS
GO:0030426	Component	Growth cone	IBA
GO:0030426	Component	Growth cone	ISS
GO:0031116	Process	Positive regulation of microtubule polymerization	ISS
GO:0031175	Process	Neuron projection development	ISS
GO:0031175	Process	Neuron projection development	TAS	17491008
GO:0031594	Component	Neuromuscular junction	ISS
GO:0032956	Process	Regulation of actin cytoskeleton organization	IEA
GO:0035235	Process	Ionotropic glutamate receptor signaling pathway	ISS
GO:0035255	Function	Ionotropic glutamate receptor binding	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0043005	Component	Neuron projection	ISS
GO:0043014	Function	Alpha-tubulin binding	ISS
GO:0043014	Function	Alpha-tubulin binding	ISS
GO:0043025	Component	Neuronal cell body	ISS
GO:0043197	Component	Dendritic spine	ISS
GO:0043204	Component	Perikaryon	IEA
GO:0043292	Component	Contractile muscle fiber	ISS
GO:0043525	Process	Positive regulation of neuron apoptotic process	ISS
GO:0043539	Function	Protein serine/threonine kinase activator activity	IDA	12832520
GO:0043539	Function	Protein serine/threonine kinase activator activity	ISS
GO:0045296	Function	Cadherin binding	ISS
GO:0045348	Process	Positive regulation of MHC class II biosynthetic process	IDA	29020624
GO:0045664	Process	Regulation of neuron differentiation	NAS	10721722
GO:0045892	Process	Negative regulation of DNA-templated transcription	IMP	20357208
GO:0048013	Process	Ephrin receptor signaling pathway	IEA
GO:0048013	Process	Ephrin receptor signaling pathway	ISS
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	12832520
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0048487	Function	Beta-tubulin binding	ISS
GO:0048487	Function	Beta-tubulin binding	ISS
GO:0048511	Process	Rhythmic process	IEA
GO:0051015	Function	Actin filament binding	IEA
GO:0061001	Process	Regulation of dendritic spine morphogenesis	IEA
GO:0061001	Process	Regulation of dendritic spine morphogenesis	ISS
GO:0061575	Function	Cyclin-dependent protein serine/threonine kinase activator activity	IBA
GO:0061575	Function	Cyclin-dependent protein serine/threonine kinase activator activity	IEA
GO:0061575	Function	Cyclin-dependent protein serine/threonine kinase activator activity	IGI	17517623
GO:0061575	Function	Cyclin-dependent protein serine/threonine kinase activator activity	TAS	17491008
GO:0070315	Process	G1 to G0 transition involved in cell differentiation	IEA
GO:0070507	Process	Regulation of microtubule cytoskeleton organization	IEA
GO:0090314	Process	Positive regulation of protein targeting to membrane	IEA
GO:1903265	Process	Positive regulation of tumor necrosis factor-mediated signaling pathway	IDA	29020624

MIM	HGNC	e!Ensembl
603460	1775	ENSG00000176749

Protein

UniProt ID

Q15078

Protein name

Cyclin-dependent kinase 5 activator 1 (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (TPKII regulatory subunit) [Cleaved into: Cyclin-dependent kinase 5 activator 1, p35 (p35); Cyclin-dependent kinase 5 activator 1, p25 (p25) (Tau pro

Protein function

p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK

PDB

1H4L , 1UNG , 1UNH , 1UNL , 3O0G , 6LDP , 7CNG , 7VDP , 7VDQ , 7VDR , 7VDS

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03261	CDK5_activator	106 → 295	Cyclin-dependent kinase 5 activator protein	Family

Tissue specificity

TISSUE SPECIFICITY: Brain and neuron specific.

Sequence

MGTVLSLSPSYRKATLFEDGAATVGHYTAVQNSKNAKDKNLKRHSIISVLPWKRIVAVSA
KKKNSKKVQPNSSYQNNITHLNNENLKKSLSCANLSTFAQPPPAQPPAPPASQLSGSQTG
GSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRS
VDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNE
ISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKR
LLLGLDR

Sequence length

307

Interactions

View interactions

	KEGG		Reactome
	Alzheimer disease Pathways of neurodegeneration - multiple diseases Cocaine addiction		CRMPs in Sema3A signaling Regulation of TP53 Activity through Phosphorylation Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models NGF-stimulated transcription

CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1)