CCK (cholecystokinin)

Gene Gene information from NCBI Gene database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID 885
Gene name Cholecystokinin
Gene symbol CCK
Synonyms (NCBI Gene)
-
Chromosome 3
Chromosome location 3p22.1
Summary This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded
miRNA miRNA information provided by mirtarbase database.
3
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
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miRTarBase ID miRNA Experiments Reference
MIRT870835 hsa-miR-1245b-3p CLIP-seq
MIRT870836 hsa-miR-3185 CLIP-seq
MIRT870837 hsa-miR-570 CLIP-seq
Transcription factors Transcription factors information provided by TRRUST V2 database.
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Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
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Transcription factor Regulation Reference
CREB1 Unknown 15030385;15073527
CREBBP Unknown 15030385
EWSR1 Unknown 17438102
FLI1 Unknown 17438102
FOS Activation 1360635
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
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GO ID Ontology Definition Evidence Reference
GO:0001764 Process Neuron migration IEA
GO:0001764 Process Neuron migration ISS 15152034
GO:0005179 Function Hormone activity IEA
GO:0005179 Function Hormone activity TAS 10320330
GO:0005184 Function Neuropeptide hormone activity IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
MIM HGNC e!Ensembl
118440 1569 ENSG00000187094
Protein Protein information from UniProt database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P06307
Protein name Cholecystokinin (CCK) [Cleaved into: Cholecystokinin-58 (CCK58); Cholecystokinin-58 desnonopeptide ((1-49)-CCK58); Cholecystokinin-39 (CCK39); Cholecystokinin-33 (CCK33); Cholecystokinin-25 (CCK25); Cholecystokinin-18 (CCK18); Cholecystokinin-12 (CCK12);
Protein function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors s
PDB 7EZH , 7EZK , 7EZM , 7MBX , 7MBY , 7XOU , 8IA7 , 9BKJ , 9BKK
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00918 Gastrin 3 → 115 Gastrin/cholecystokinin family Family
Tissue specificity TISSUE SPECIFICITY: Detected in cerebrospinal fluid and urine (at protein level). {ECO:0000269|PubMed:25326458, ECO:0000269|PubMed:37453717}.
Sequence
Sequence length 115
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
  KEGG  Reactome
  Neuroactive ligand-receptor interaction
Hormone signaling
Insulin secretion
Pancreatic secretion 		  Peptide ligand-binding receptors
G alpha (q) signalling events