Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8848
Gene name Gene Name - the full gene name approved by the HGNC.	TSC22 domain family member 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TSC22D1
Synonyms (NCBI Gene) Gene synonyms aliases	HUCEP-2, Ptg-2, TGFB1I4, TSC22
Chromosome Chromosome number	13
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	13q14.11
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. Th

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miRTarBase ID	miRNA	Experiments	Reference
MIRT048416	hsa-miR-100-5p	CLASH	23622248
MIRT486481	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT486482	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT486480	hsa-miR-28-5p	PAR-CLIP	23592263
MIRT486479	hsa-miR-3139	PAR-CLIP	23592263
MIRT486478	hsa-miR-708-5p	PAR-CLIP	23592263
MIRT486477	hsa-miR-1825	PAR-CLIP	23592263
MIRT486476	hsa-miR-199a-5p	PAR-CLIP	23592263
MIRT486475	hsa-miR-199b-5p	PAR-CLIP	23592263
MIRT486474	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT486473	hsa-miR-4784	PAR-CLIP	23592263
MIRT486472	hsa-miR-4689	PAR-CLIP	23592263
MIRT486471	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT441495	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT441494	hsa-miR-9-3p	PAR-CLIP	22100165
MIRT441495	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT441494	hsa-miR-9-3p	PAR-CLIP	22100165
MIRT486481	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT486482	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT486480	hsa-miR-28-5p	PAR-CLIP	23592263
MIRT486479	hsa-miR-3139	PAR-CLIP	23592263
MIRT486478	hsa-miR-708-5p	PAR-CLIP	23592263
MIRT486477	hsa-miR-1825	PAR-CLIP	23592263
MIRT486476	hsa-miR-199a-5p	PAR-CLIP	23592263
MIRT486475	hsa-miR-199b-5p	PAR-CLIP	23592263
MIRT486474	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT486473	hsa-miR-4784	PAR-CLIP	23592263
MIRT486472	hsa-miR-4689	PAR-CLIP	23592263
MIRT486471	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT441495	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT441494	hsa-miR-9-3p	PAR-CLIP	22100165
MIRT441495	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT441494	hsa-miR-9-3p	PAR-CLIP	22100165
MIRT1458131	hsa-miR-125a-3p	CLIP-seq
MIRT1458132	hsa-miR-1284	CLIP-seq
MIRT1458133	hsa-miR-190	CLIP-seq
MIRT1458134	hsa-miR-190b	CLIP-seq
MIRT1458135	hsa-miR-3689a-5p	CLIP-seq
MIRT1458136	hsa-miR-3689b	CLIP-seq
MIRT1458137	hsa-miR-3689e	CLIP-seq
MIRT1458138	hsa-miR-3689f	CLIP-seq
MIRT1458139	hsa-miR-410	CLIP-seq
MIRT1458140	hsa-miR-448	CLIP-seq
MIRT1458141	hsa-miR-4639-3p	CLIP-seq
MIRT1458142	hsa-miR-494	CLIP-seq
MIRT1458143	hsa-miR-552	CLIP-seq
MIRT1458144	hsa-miR-586	CLIP-seq
MIRT1458145	hsa-miR-606	CLIP-seq
MIRT1458146	hsa-miR-668	CLIP-seq
MIRT1458147	hsa-miR-1227	CLIP-seq
MIRT1458148	hsa-miR-1228	CLIP-seq
MIRT1458149	hsa-miR-1244	CLIP-seq
MIRT1458150	hsa-miR-1262	CLIP-seq
MIRT1458151	hsa-miR-1324	CLIP-seq
MIRT1458152	hsa-miR-134	CLIP-seq
MIRT1458153	hsa-miR-1827	CLIP-seq
MIRT1458154	hsa-miR-1910	CLIP-seq
MIRT1458155	hsa-miR-203	CLIP-seq
MIRT1458156	hsa-miR-205	CLIP-seq
MIRT1458157	hsa-miR-214	CLIP-seq
MIRT1458158	hsa-miR-300	CLIP-seq
MIRT1458159	hsa-miR-3118	CLIP-seq
MIRT1458160	hsa-miR-3121-3p	CLIP-seq
MIRT1458161	hsa-miR-3163	CLIP-seq
MIRT1458162	hsa-miR-3174	CLIP-seq
MIRT1458163	hsa-miR-338-5p	CLIP-seq
MIRT1458164	hsa-miR-3605-3p	CLIP-seq
MIRT1458165	hsa-miR-3609	CLIP-seq
MIRT1458166	hsa-miR-3612	CLIP-seq
MIRT1458167	hsa-miR-3619-5p	CLIP-seq
MIRT1458168	hsa-miR-3664-5p	CLIP-seq
MIRT1458169	hsa-miR-3668	CLIP-seq
MIRT1458170	hsa-miR-3679-3p	CLIP-seq
MIRT1458171	hsa-miR-3682-5p	CLIP-seq
MIRT1458172	hsa-miR-381	CLIP-seq
MIRT1458173	hsa-miR-3908	CLIP-seq
MIRT1458174	hsa-miR-3909	CLIP-seq
MIRT1458175	hsa-miR-3917	CLIP-seq
MIRT1458176	hsa-miR-3924	CLIP-seq
MIRT1458177	hsa-miR-3935	CLIP-seq
MIRT1458178	hsa-miR-3941	CLIP-seq
MIRT1458179	hsa-miR-3942-3p	CLIP-seq
MIRT1458139	hsa-miR-410	CLIP-seq
MIRT1458180	hsa-miR-4267	CLIP-seq
MIRT1458181	hsa-miR-4272	CLIP-seq
MIRT1458182	hsa-miR-4276	CLIP-seq
MIRT1458183	hsa-miR-4281	CLIP-seq
MIRT1458184	hsa-miR-4287	CLIP-seq
MIRT1458185	hsa-miR-4291	CLIP-seq
MIRT1458186	hsa-miR-4318	CLIP-seq
MIRT1458187	hsa-miR-4328	CLIP-seq
MIRT1458188	hsa-miR-4330	CLIP-seq
MIRT1458189	hsa-miR-4443	CLIP-seq
MIRT1458190	hsa-miR-4449	CLIP-seq
MIRT1458191	hsa-miR-4469	CLIP-seq
MIRT1458192	hsa-miR-4474-5p	CLIP-seq
MIRT1458140	hsa-miR-448	CLIP-seq
MIRT1458193	hsa-miR-4480	CLIP-seq
MIRT1458194	hsa-miR-4506	CLIP-seq
MIRT1458195	hsa-miR-4645-3p	CLIP-seq
MIRT1458196	hsa-miR-466	CLIP-seq
MIRT1458197	hsa-miR-4666-3p	CLIP-seq
MIRT1458198	hsa-miR-4672	CLIP-seq
MIRT1458199	hsa-miR-4680-5p	CLIP-seq
MIRT1458200	hsa-miR-4685-3p	CLIP-seq
MIRT1458201	hsa-miR-4686	CLIP-seq
MIRT1458202	hsa-miR-4699-3p	CLIP-seq
MIRT1458203	hsa-miR-4701-3p	CLIP-seq
MIRT1458204	hsa-miR-4704-5p	CLIP-seq
MIRT1458205	hsa-miR-4713-5p	CLIP-seq
MIRT1458206	hsa-miR-4714-3p	CLIP-seq
MIRT1458207	hsa-miR-4719	CLIP-seq
MIRT1458208	hsa-miR-4727-5p	CLIP-seq
MIRT1458209	hsa-miR-4731-3p	CLIP-seq
MIRT1458210	hsa-miR-4753-3p	CLIP-seq
MIRT1458211	hsa-miR-4769-3p	CLIP-seq
MIRT1458212	hsa-miR-4783-3p	CLIP-seq
MIRT1458213	hsa-miR-4801	CLIP-seq
MIRT1458214	hsa-miR-488	CLIP-seq
MIRT1458142	hsa-miR-494	CLIP-seq
MIRT1458215	hsa-miR-513a-3p	CLIP-seq
MIRT1458216	hsa-miR-520g	CLIP-seq
MIRT1458217	hsa-miR-520h	CLIP-seq
MIRT1458218	hsa-miR-548ah	CLIP-seq
MIRT1458219	hsa-miR-548n	CLIP-seq
MIRT1458220	hsa-miR-548p	CLIP-seq
MIRT1458221	hsa-miR-548t	CLIP-seq
MIRT1458222	hsa-miR-548u	CLIP-seq
MIRT1458223	hsa-miR-582-5p	CLIP-seq
MIRT1458144	hsa-miR-586	CLIP-seq
MIRT1458145	hsa-miR-606	CLIP-seq
MIRT1458224	hsa-miR-646	CLIP-seq
MIRT1458225	hsa-miR-650	CLIP-seq
MIRT1458226	hsa-miR-761	CLIP-seq
MIRT1458227	hsa-miR-922	CLIP-seq
MIRT1458228	hsa-miR-942	CLIP-seq
MIRT1458229	hsa-miR-943	CLIP-seq
MIRT1458133	hsa-miR-190	CLIP-seq
MIRT1458134	hsa-miR-190b	CLIP-seq
MIRT2137492	hsa-miR-298	CLIP-seq
MIRT2137493	hsa-miR-3123	CLIP-seq
MIRT2137494	hsa-miR-3153	CLIP-seq
MIRT2137495	hsa-miR-3925-5p	CLIP-seq
MIRT1458139	hsa-miR-410	CLIP-seq
MIRT2137496	hsa-miR-4646-5p	CLIP-seq
MIRT2137497	hsa-miR-4668-5p	CLIP-seq
MIRT2137498	hsa-miR-4732-5p	CLIP-seq
MIRT1458214	hsa-miR-488	CLIP-seq
MIRT1458142	hsa-miR-494	CLIP-seq
MIRT1458215	hsa-miR-513a-3p	CLIP-seq
MIRT1458142	hsa-miR-494	CLIP-seq
MIRT1458148	hsa-miR-1228	CLIP-seq
MIRT1458150	hsa-miR-1262	CLIP-seq
MIRT1458151	hsa-miR-1324	CLIP-seq
MIRT1458152	hsa-miR-134	CLIP-seq
MIRT1458153	hsa-miR-1827	CLIP-seq
MIRT1458155	hsa-miR-203	CLIP-seq
MIRT2358314	hsa-miR-2113	CLIP-seq
MIRT1458157	hsa-miR-214	CLIP-seq
MIRT2358315	hsa-miR-223	CLIP-seq
MIRT1458159	hsa-miR-3118	CLIP-seq
MIRT2137493	hsa-miR-3123	CLIP-seq
MIRT1458166	hsa-miR-3612	CLIP-seq
MIRT1458167	hsa-miR-3619-5p	CLIP-seq
MIRT1458171	hsa-miR-3682-5p	CLIP-seq
MIRT1458173	hsa-miR-3908	CLIP-seq
MIRT2137495	hsa-miR-3925-5p	CLIP-seq
MIRT1458182	hsa-miR-4276	CLIP-seq
MIRT1458184	hsa-miR-4287	CLIP-seq
MIRT1458185	hsa-miR-4291	CLIP-seq
MIRT1458186	hsa-miR-4318	CLIP-seq
MIRT1458189	hsa-miR-4443	CLIP-seq
MIRT1458191	hsa-miR-4469	CLIP-seq
MIRT1458194	hsa-miR-4506	CLIP-seq
MIRT1458141	hsa-miR-4639-3p	CLIP-seq
MIRT1458200	hsa-miR-4685-3p	CLIP-seq
MIRT2358316	hsa-miR-4697-3p	CLIP-seq
MIRT1458202	hsa-miR-4699-3p	CLIP-seq
MIRT1458203	hsa-miR-4701-3p	CLIP-seq
MIRT1458205	hsa-miR-4713-5p	CLIP-seq
MIRT2137498	hsa-miR-4732-5p	CLIP-seq
MIRT1458210	hsa-miR-4753-3p	CLIP-seq
MIRT1458214	hsa-miR-488	CLIP-seq
MIRT1458142	hsa-miR-494	CLIP-seq
MIRT1458215	hsa-miR-513a-3p	CLIP-seq
MIRT2358317	hsa-miR-515-5p	CLIP-seq
MIRT1458219	hsa-miR-548n	CLIP-seq
MIRT1458221	hsa-miR-548t	CLIP-seq
MIRT2358318	hsa-miR-592	CLIP-seq
MIRT2358319	hsa-miR-597	CLIP-seq
MIRT2358320	hsa-miR-599	CLIP-seq
MIRT2358321	hsa-miR-622	CLIP-seq
MIRT1458224	hsa-miR-646	CLIP-seq
MIRT1458225	hsa-miR-650	CLIP-seq
MIRT1458146	hsa-miR-668	CLIP-seq
MIRT1458226	hsa-miR-761	CLIP-seq
MIRT1458227	hsa-miR-922	CLIP-seq
MIRT1458229	hsa-miR-943	CLIP-seq
MIRT2358322	hsa-miR-4282	CLIP-seq
MIRT1458215	hsa-miR-513a-3p	CLIP-seq
MIRT1458152	hsa-miR-134	CLIP-seq
MIRT1458159	hsa-miR-3118	CLIP-seq
MIRT2137493	hsa-miR-3123	CLIP-seq
MIRT2396398	hsa-miR-3659	CLIP-seq
MIRT2137495	hsa-miR-3925-5p	CLIP-seq
MIRT1458186	hsa-miR-4318	CLIP-seq
MIRT1458195	hsa-miR-4645-3p	CLIP-seq
MIRT2396399	hsa-miR-4658	CLIP-seq
MIRT2137498	hsa-miR-4732-5p	CLIP-seq
MIRT2396400	hsa-miR-542-3p	CLIP-seq
MIRT2396401	hsa-miR-574-5p	CLIP-seq
MIRT1458229	hsa-miR-943	CLIP-seq
MIRT1458160	hsa-miR-3121-3p	CLIP-seq
MIRT2651599	hsa-miR-101	CLIP-seq
MIRT1458149	hsa-miR-1244	CLIP-seq
MIRT2651600	hsa-miR-1253	CLIP-seq
MIRT1458131	hsa-miR-125a-3p	CLIP-seq
MIRT1458132	hsa-miR-1284	CLIP-seq
MIRT2651601	hsa-miR-1305	CLIP-seq
MIRT1458133	hsa-miR-190	CLIP-seq
MIRT1458134	hsa-miR-190b	CLIP-seq
MIRT1458154	hsa-miR-1910	CLIP-seq
MIRT2358314	hsa-miR-2113	CLIP-seq
MIRT2137492	hsa-miR-298	CLIP-seq
MIRT1458160	hsa-miR-3121-3p	CLIP-seq
MIRT2137493	hsa-miR-3123	CLIP-seq
MIRT2137494	hsa-miR-3153	CLIP-seq
MIRT1458135	hsa-miR-3689a-5p	CLIP-seq
MIRT1458136	hsa-miR-3689b	CLIP-seq
MIRT1458137	hsa-miR-3689e	CLIP-seq
MIRT1458138	hsa-miR-3689f	CLIP-seq
MIRT1458174	hsa-miR-3909	CLIP-seq
MIRT2137495	hsa-miR-3925-5p	CLIP-seq
MIRT2651602	hsa-miR-3973	CLIP-seq
MIRT1458139	hsa-miR-410	CLIP-seq
MIRT1458180	hsa-miR-4267	CLIP-seq
MIRT1458181	hsa-miR-4272	CLIP-seq
MIRT1458182	hsa-miR-4276	CLIP-seq
MIRT1458140	hsa-miR-448	CLIP-seq
MIRT1458141	hsa-miR-4639-3p	CLIP-seq
MIRT2137496	hsa-miR-4646-5p	CLIP-seq
MIRT2137497	hsa-miR-4668-5p	CLIP-seq
MIRT1458206	hsa-miR-4714-3p	CLIP-seq
MIRT2137498	hsa-miR-4732-5p	CLIP-seq
MIRT1458214	hsa-miR-488	CLIP-seq
MIRT1458142	hsa-miR-494	CLIP-seq
MIRT1458215	hsa-miR-513a-3p	CLIP-seq
MIRT1458216	hsa-miR-520g	CLIP-seq
MIRT1458217	hsa-miR-520h	CLIP-seq
MIRT2651603	hsa-miR-548l	CLIP-seq
MIRT1458222	hsa-miR-548u	CLIP-seq
MIRT1458143	hsa-miR-552	CLIP-seq
MIRT2651604	hsa-miR-580	CLIP-seq
MIRT1458223	hsa-miR-582-5p	CLIP-seq
MIRT2651605	hsa-miR-583	CLIP-seq
MIRT1458144	hsa-miR-586	CLIP-seq
MIRT2358318	hsa-miR-592	CLIP-seq
MIRT2358319	hsa-miR-597	CLIP-seq
MIRT2358320	hsa-miR-599	CLIP-seq
MIRT1458145	hsa-miR-606	CLIP-seq
MIRT2651606	hsa-miR-607	CLIP-seq
MIRT1458146	hsa-miR-668	CLIP-seq
MIRT2651599	hsa-miR-101	CLIP-seq
MIRT1458149	hsa-miR-1244	CLIP-seq
MIRT2651600	hsa-miR-1253	CLIP-seq
MIRT1458131	hsa-miR-125a-3p	CLIP-seq
MIRT1458132	hsa-miR-1284	CLIP-seq
MIRT2651601	hsa-miR-1305	CLIP-seq
MIRT1458133	hsa-miR-190	CLIP-seq
MIRT1458134	hsa-miR-190b	CLIP-seq
MIRT1458154	hsa-miR-1910	CLIP-seq
MIRT2358314	hsa-miR-2113	CLIP-seq
MIRT2137492	hsa-miR-298	CLIP-seq
MIRT1458160	hsa-miR-3121-3p	CLIP-seq
MIRT2137493	hsa-miR-3123	CLIP-seq
MIRT2137494	hsa-miR-3153	CLIP-seq
MIRT1458135	hsa-miR-3689a-5p	CLIP-seq
MIRT1458136	hsa-miR-3689b	CLIP-seq
MIRT1458137	hsa-miR-3689e	CLIP-seq
MIRT1458138	hsa-miR-3689f	CLIP-seq
MIRT1458174	hsa-miR-3909	CLIP-seq
MIRT2137495	hsa-miR-3925-5p	CLIP-seq
MIRT2651602	hsa-miR-3973	CLIP-seq
MIRT1458139	hsa-miR-410	CLIP-seq
MIRT1458180	hsa-miR-4267	CLIP-seq
MIRT1458181	hsa-miR-4272	CLIP-seq
MIRT1458182	hsa-miR-4276	CLIP-seq
MIRT1458140	hsa-miR-448	CLIP-seq
MIRT1458141	hsa-miR-4639-3p	CLIP-seq
MIRT1458195	hsa-miR-4645-3p	CLIP-seq
MIRT2137496	hsa-miR-4646-5p	CLIP-seq
MIRT2137497	hsa-miR-4668-5p	CLIP-seq
MIRT1458206	hsa-miR-4714-3p	CLIP-seq
MIRT2137498	hsa-miR-4732-5p	CLIP-seq
MIRT1458214	hsa-miR-488	CLIP-seq
MIRT1458142	hsa-miR-494	CLIP-seq
MIRT1458215	hsa-miR-513a-3p	CLIP-seq
MIRT1458216	hsa-miR-520g	CLIP-seq
MIRT1458217	hsa-miR-520h	CLIP-seq
MIRT2396400	hsa-miR-542-3p	CLIP-seq
MIRT2651603	hsa-miR-548l	CLIP-seq
MIRT1458222	hsa-miR-548u	CLIP-seq
MIRT1458143	hsa-miR-552	CLIP-seq
MIRT2651604	hsa-miR-580	CLIP-seq
MIRT1458223	hsa-miR-582-5p	CLIP-seq
MIRT2651605	hsa-miR-583	CLIP-seq
MIRT1458144	hsa-miR-586	CLIP-seq
MIRT2358318	hsa-miR-592	CLIP-seq
MIRT2358319	hsa-miR-597	CLIP-seq
MIRT2358320	hsa-miR-599	CLIP-seq
MIRT1458145	hsa-miR-606	CLIP-seq
MIRT2651606	hsa-miR-607	CLIP-seq
MIRT1458146	hsa-miR-668	CLIP-seq

Show/Hide all(24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003713	Function	Transcription coactivator activity	IMP	15881652
GO:0005515	Function	Protein binding	IPI	15881652, 18325344, 21448135, 21791611, 25416956, 31515488, 32296183, 32814053, 34681573
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	34681573
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA	21791611, 34681573
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IDA	34681573
GO:0005739	Component	Mitochondrion	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005886	Component	Plasma membrane	IDA	21791611
GO:0005886	Component	Plasma membrane	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0006366	Process	Transcription by RNA polymerase II	TAS	9022669
GO:0008284	Process	Positive regulation of cell population proliferation	IBA
GO:0016020	Component	Membrane	IEA
GO:0030511	Process	Positive regulation of transforming growth factor beta receptor signaling pathway	IMP	21791611
GO:0042802	Function	Identical protein binding	IDA	26752201
GO:0043065	Process	Positive regulation of apoptotic process	IMP	18325344
GO:0043066	Process	Negative regulation of apoptotic process	IBA
GO:0043068	Process	Positive regulation of programmed cell death	ISS
GO:0043069	Process	Negative regulation of programmed cell death	ISS
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:1902034	Process	Negative regulation of hematopoietic stem cell proliferation	ISS

MIM	HGNC	e!Ensembl
607715	16826	ENSG00000102804

Protein

UniProt ID

Q15714

Protein name

TSC22 domain family protein 1 (Cerebral protein 2) (HUCEP-2) (Regulatory protein TSC-22) (TGFB-stimulated clone 22 homolog) (Transforming growth factor beta-1-induced transcript 4 protein)

Protein function

Transcriptional repressor (PubMed:10488076). Acts on the C-type natriuretic peptide (CNP) promoter (PubMed:9022669). Acts to promote CASP3-mediated apoptosis (PubMed:18325344). Positively regulates TGF-beta signaling by interacting with SMAD7 wh

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01166	TSC22	988 → 1044	TSC-22/dip/bun family	Coiled-coil

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed in adult tissues (PubMed:26752201, PubMed:8651929). Expressed in the postmitotic epithelial compartment at the top of intestinal mucosal villi (PubMed:12468551). {ECO:0000269|PubMed:12468551, ECO:0000269|PubMed:2

Sequence

MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPP
PSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQ
ISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNF
QEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPS
HVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTG
GIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVN
VNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFK
KGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHY
TESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS
QSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSL
AQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQ
PILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAV
SAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTS
APSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTG
PSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQ
SLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPL
TTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQL
EQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA

Sequence length

1073

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS
Psoriasis	Psoriasis	N/A	N/A	GWAS
Psoriasis vulgaris	Psoriasis vulgaris	N/A	N/A	GWAS

Show/Hide Text Mining Associations (16)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Alzheimer Disease	Associate	29935546
Brain Neoplasms	Inhibit	12501169
Breast Neoplasms	Associate	9195978
Diabetes Mellitus Type 2	Associate	30649532
HIV Infections	Associate	30649532
Inflammation	Associate	21448135, 30649532
Leukemia Myeloid Acute	Associate	25605239, 37237254
Lung Neoplasms	Associate	27171439
Melanosis	Associate	35840442
Neoplasms	Inhibit	12501169, 25605239
Neoplasms	Associate	21448135
Osteoarthritis	Associate	15922185
Ovarian Neoplasms	Associate	18325344
Salivary Gland Diseases	Associate	10879745
Salivary Gland Neoplasms	Associate	10879745, 12501169, 9459148
Stomach Neoplasms	Associate	9210400

TSC22D1 (TSC22 domain family member 1)