DPM2 (dolichyl-phosphate mannosyltransferase subunit 2, regulatory)

Gene

• Entrez ID: 8818
• Gene name: Dolichyl-phosphate mannosyltransferase subunit 2, regulatory
• Gene symbol: DPM2
• Synonyms (NCBI Gene): CDG1U
• Chromosome: 9
• Chromosome location: 9q34.11
• Summary: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mann

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs397514503	T>C	Pathogenic	Intron variant, non coding transcript variant, missense variant, coding sequence variant
rs797044467	C>G,T	Pathogenic	Intron variant, splice acceptor variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT477982	hsa-miR-634	PAR-CLIP	23592263
MIRT477981	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT477980	hsa-miR-4779	PAR-CLIP	23592263
MIRT477979	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT477978	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT477977	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT477976	hsa-miR-4501	PAR-CLIP	23592263
MIRT477975	hsa-miR-4459	PAR-CLIP	23592263
MIRT477974	hsa-miR-4270	PAR-CLIP	23592263
MIRT477973	hsa-miR-4441	PAR-CLIP	23592263
MIRT477972	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT477971	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT477970	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT477969	hsa-miR-4251	PAR-CLIP	23592263
MIRT477968	hsa-miR-4329	PAR-CLIP	23592263
MIRT477967	hsa-miR-6761-5p	PAR-CLIP	23592263
MIRT477966	hsa-miR-4693-3p	PAR-CLIP	23592263
MIRT477965	hsa-miR-4751	PAR-CLIP	23592263
MIRT477964	hsa-miR-1827	PAR-CLIP	23592263
MIRT477963	hsa-miR-655-5p	PAR-CLIP	23592263
MIRT477962	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT477961	hsa-miR-6086	PAR-CLIP	23592263
MIRT477960	hsa-miR-4696	PAR-CLIP	23592263
MIRT477959	hsa-miR-6124	PAR-CLIP	23592263
MIRT477958	hsa-miR-4294	PAR-CLIP	23592263
MIRT477957	hsa-miR-31-5p	PAR-CLIP	23592263
MIRT477956	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT477955	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT477954	hsa-miR-4736	PAR-CLIP	23592263
MIRT477953	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT477952	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT477951	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT477950	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT477949	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT477948	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT477947	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT477946	hsa-miR-4271	PAR-CLIP	23592263
MIRT477945	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT477944	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT477943	hsa-miR-92a-1-5p	PAR-CLIP	23592263
MIRT477942	hsa-miR-4504	PAR-CLIP	23592263
MIRT477941	hsa-miR-542-3p	PAR-CLIP	23592263
MIRT477940	hsa-miR-4316	PAR-CLIP	23592263
MIRT477939	hsa-miR-1294	PAR-CLIP	23592263
MIRT477938	hsa-miR-4425	PAR-CLIP	23592263
MIRT477937	hsa-miR-7150	PAR-CLIP	23592263
MIRT477936	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT477935	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT477934	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT477933	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT477932	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT477931	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT477930	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT477929	hsa-miR-3689c	PAR-CLIP	23592263
MIRT477928	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT477927	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT477926	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT440779	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440779	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT477956	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT477951	hsa-miR-149-3p	PAR-CLIP	26701625
MIRT477964	hsa-miR-1827	PAR-CLIP	26701625
MIRT477964	hsa-miR-1827	PAR-CLIP	26701625
MIRT477971	hsa-miR-1915-3p	PAR-CLIP	26701625
MIRT477957	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT477957	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT477946	hsa-miR-4271	PAR-CLIP	26701625
MIRT477946	hsa-miR-4271	PAR-CLIP	26701625
MIRT477940	hsa-miR-4316	PAR-CLIP	26701625
MIRT477940	hsa-miR-4316	PAR-CLIP	26701625
MIRT477975	hsa-miR-4459	PAR-CLIP	26701625
MIRT477975	hsa-miR-4459	PAR-CLIP	26701625
MIRT477976	hsa-miR-4501	PAR-CLIP	26701625
MIRT477976	hsa-miR-4501	PAR-CLIP	26701625
MIRT477942	hsa-miR-4504	PAR-CLIP	26701625
MIRT477942	hsa-miR-4504	PAR-CLIP	26701625
MIRT477953	hsa-miR-4668-5p	PAR-CLIP	26701625
MIRT477960	hsa-miR-4696	PAR-CLIP	26701625
MIRT477960	hsa-miR-4696	PAR-CLIP	26701625
MIRT477945	hsa-miR-4725-3p	PAR-CLIP	26701625
MIRT477945	hsa-miR-4725-3p	PAR-CLIP	26701625
MIRT477950	hsa-miR-4728-5p	PAR-CLIP	26701625
MIRT477954	hsa-miR-4736	PAR-CLIP	26701625
MIRT477955	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT477980	hsa-miR-4779	PAR-CLIP	26701625
MIRT477980	hsa-miR-4779	PAR-CLIP	26701625
MIRT477941	hsa-miR-542-3p	PAR-CLIP	26701625
MIRT477941	hsa-miR-542-3p	PAR-CLIP	26701625
MIRT477959	hsa-miR-6124	PAR-CLIP	26701625
MIRT477970	hsa-miR-6764-5p	PAR-CLIP	26701625
MIRT477944	hsa-miR-6780b-5p	PAR-CLIP	26701625
MIRT477944	hsa-miR-6780b-5p	PAR-CLIP	26701625
MIRT477979	hsa-miR-6783-5p	PAR-CLIP	26701625
MIRT477979	hsa-miR-6783-5p	PAR-CLIP	26701625
MIRT477949	hsa-miR-6785-5p	PAR-CLIP	26701625
MIRT477978	hsa-miR-6815-5p	PAR-CLIP	26701625
MIRT477977	hsa-miR-6865-5p	PAR-CLIP	26701625
MIRT477948	hsa-miR-6883-5p	PAR-CLIP	26701625
MIRT477937	hsa-miR-7150	PAR-CLIP	26701625
MIRT477982	hsa-miR-634	PAR-CLIP	23592263
MIRT477981	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT477980	hsa-miR-4779	PAR-CLIP	23592263
MIRT477979	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT477978	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT477977	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT477976	hsa-miR-4501	PAR-CLIP	23592263
MIRT477975	hsa-miR-4459	PAR-CLIP	23592263
MIRT477974	hsa-miR-4270	PAR-CLIP	23592263
MIRT477973	hsa-miR-4441	PAR-CLIP	23592263
MIRT477972	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT477971	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT477970	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT477969	hsa-miR-4251	PAR-CLIP	23592263
MIRT477968	hsa-miR-4329	PAR-CLIP	23592263
MIRT477967	hsa-miR-6761-5p	PAR-CLIP	23592263
MIRT477966	hsa-miR-4693-3p	PAR-CLIP	23592263
MIRT477965	hsa-miR-4751	PAR-CLIP	23592263
MIRT477964	hsa-miR-1827	PAR-CLIP	23592263
MIRT477963	hsa-miR-655-5p	PAR-CLIP	23592263
MIRT477962	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT477961	hsa-miR-6086	PAR-CLIP	23592263
MIRT477960	hsa-miR-4696	PAR-CLIP	23592263
MIRT477959	hsa-miR-6124	PAR-CLIP	23592263
MIRT477958	hsa-miR-4294	PAR-CLIP	23592263
MIRT477957	hsa-miR-31-5p	PAR-CLIP	23592263
MIRT477956	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT477955	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT477954	hsa-miR-4736	PAR-CLIP	23592263
MIRT477953	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT477952	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT477951	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT477950	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT477949	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT477948	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT477947	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT477946	hsa-miR-4271	PAR-CLIP	23592263
MIRT477945	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT477944	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT477943	hsa-miR-92a-1-5p	PAR-CLIP	23592263
MIRT477942	hsa-miR-4504	PAR-CLIP	23592263
MIRT477941	hsa-miR-542-3p	PAR-CLIP	23592263
MIRT477940	hsa-miR-4316	PAR-CLIP	23592263
MIRT477939	hsa-miR-1294	PAR-CLIP	23592263
MIRT477938	hsa-miR-4425	PAR-CLIP	23592263
MIRT477937	hsa-miR-7150	PAR-CLIP	23592263
MIRT477936	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT477935	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT477934	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT477933	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT477932	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT477931	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT477930	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT477929	hsa-miR-3689c	PAR-CLIP	23592263
MIRT477928	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT477927	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT477926	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT944052	hsa-miR-1207-3p	CLIP-seq
MIRT944053	hsa-miR-1224-5p	CLIP-seq
MIRT944054	hsa-miR-1254	CLIP-seq
MIRT944055	hsa-miR-125a-5p	CLIP-seq
MIRT944056	hsa-miR-125b	CLIP-seq
MIRT944057	hsa-miR-1287	CLIP-seq
MIRT944058	hsa-miR-1291	CLIP-seq
MIRT944059	hsa-miR-1295	CLIP-seq
MIRT944060	hsa-miR-1538	CLIP-seq
MIRT944061	hsa-miR-1914	CLIP-seq
MIRT944062	hsa-miR-1915	CLIP-seq
MIRT944063	hsa-miR-198	CLIP-seq
MIRT944064	hsa-miR-2861	CLIP-seq
MIRT944065	hsa-miR-31	CLIP-seq
MIRT944066	hsa-miR-3116	CLIP-seq
MIRT944067	hsa-miR-3135b	CLIP-seq
MIRT944068	hsa-miR-3150b-3p	CLIP-seq
MIRT944069	hsa-miR-3151	CLIP-seq
MIRT944070	hsa-miR-3154	CLIP-seq
MIRT944071	hsa-miR-3179	CLIP-seq
MIRT944072	hsa-miR-3180-5p	CLIP-seq
MIRT944073	hsa-miR-3194-5p	CLIP-seq
MIRT944074	hsa-miR-320a	CLIP-seq
MIRT944075	hsa-miR-320b	CLIP-seq
MIRT944076	hsa-miR-320c	CLIP-seq
MIRT944077	hsa-miR-320d	CLIP-seq
MIRT944078	hsa-miR-338-3p	CLIP-seq
MIRT944079	hsa-miR-339-5p	CLIP-seq
MIRT944080	hsa-miR-3605-3p	CLIP-seq
MIRT944081	hsa-miR-3607-5p	CLIP-seq
MIRT944082	hsa-miR-3649	CLIP-seq
MIRT944083	hsa-miR-3690	CLIP-seq
MIRT944084	hsa-miR-377	CLIP-seq
MIRT944085	hsa-miR-3915	CLIP-seq
MIRT944086	hsa-miR-3919	CLIP-seq
MIRT944087	hsa-miR-4252	CLIP-seq
MIRT944088	hsa-miR-4260	CLIP-seq
MIRT944089	hsa-miR-4265	CLIP-seq
MIRT944090	hsa-miR-4292	CLIP-seq
MIRT944091	hsa-miR-4296	CLIP-seq
MIRT944092	hsa-miR-4310	CLIP-seq
MIRT944093	hsa-miR-4319	CLIP-seq
MIRT944094	hsa-miR-4322	CLIP-seq
MIRT944095	hsa-miR-4429	CLIP-seq
MIRT944096	hsa-miR-4447	CLIP-seq
MIRT944097	hsa-miR-4472	CLIP-seq
MIRT944098	hsa-miR-4489	CLIP-seq
MIRT944099	hsa-miR-4492	CLIP-seq
MIRT944100	hsa-miR-4498	CLIP-seq
MIRT944101	hsa-miR-4505	CLIP-seq
MIRT944102	hsa-miR-4532	CLIP-seq
MIRT944103	hsa-miR-4638-3p	CLIP-seq
MIRT944104	hsa-miR-4639-5p	CLIP-seq
MIRT944105	hsa-miR-4640-5p	CLIP-seq
MIRT944106	hsa-miR-4643	CLIP-seq
MIRT944107	hsa-miR-4651	CLIP-seq
MIRT944108	hsa-miR-4667-5p	CLIP-seq
MIRT944109	hsa-miR-4675	CLIP-seq
MIRT944110	hsa-miR-4689	CLIP-seq
MIRT944111	hsa-miR-4700-5p	CLIP-seq
MIRT944112	hsa-miR-4726-5p	CLIP-seq
MIRT944113	hsa-miR-4734	CLIP-seq
MIRT944114	hsa-miR-4741	CLIP-seq
MIRT944115	hsa-miR-4745-3p	CLIP-seq
MIRT944116	hsa-miR-4747-3p	CLIP-seq
MIRT944117	hsa-miR-4784	CLIP-seq
MIRT944118	hsa-miR-491-5p	CLIP-seq
MIRT944119	hsa-miR-550a	CLIP-seq
MIRT944120	hsa-miR-555	CLIP-seq
MIRT944121	hsa-miR-592	CLIP-seq
MIRT944122	hsa-miR-597	CLIP-seq
MIRT944123	hsa-miR-608	CLIP-seq
MIRT944124	hsa-miR-615-5p	CLIP-seq
MIRT944125	hsa-miR-637	CLIP-seq
MIRT944126	hsa-miR-661	CLIP-seq
MIRT944127	hsa-miR-663b	CLIP-seq
MIRT944128	hsa-miR-762	CLIP-seq
MIRT944129	hsa-miR-885-3p	CLIP-seq
MIRT944062	hsa-miR-1915	CLIP-seq
MIRT1979548	hsa-miR-1184	CLIP-seq
MIRT1979549	hsa-miR-1205	CLIP-seq
MIRT944053	hsa-miR-1224-5p	CLIP-seq
MIRT944054	hsa-miR-1254	CLIP-seq
MIRT944055	hsa-miR-125a-5p	CLIP-seq
MIRT944056	hsa-miR-125b	CLIP-seq
MIRT1979550	hsa-miR-1286	CLIP-seq
MIRT944062	hsa-miR-1915	CLIP-seq
MIRT1979551	hsa-miR-22	CLIP-seq
MIRT944064	hsa-miR-2861	CLIP-seq
MIRT944065	hsa-miR-31	CLIP-seq
MIRT944066	hsa-miR-3116	CLIP-seq
MIRT1979552	hsa-miR-3144-5p	CLIP-seq
MIRT944068	hsa-miR-3150b-3p	CLIP-seq
MIRT944069	hsa-miR-3151	CLIP-seq
MIRT1979553	hsa-miR-3158-5p	CLIP-seq
MIRT1979554	hsa-miR-3165	CLIP-seq
MIRT1979555	hsa-miR-3191	CLIP-seq
MIRT944074	hsa-miR-320a	CLIP-seq
MIRT944075	hsa-miR-320b	CLIP-seq
MIRT944076	hsa-miR-320c	CLIP-seq
MIRT944077	hsa-miR-320d	CLIP-seq
MIRT944080	hsa-miR-3605-3p	CLIP-seq
MIRT944081	hsa-miR-3607-5p	CLIP-seq
MIRT944083	hsa-miR-3690	CLIP-seq
MIRT944084	hsa-miR-377	CLIP-seq
MIRT944085	hsa-miR-3915	CLIP-seq
MIRT944086	hsa-miR-3919	CLIP-seq
MIRT1979556	hsa-miR-3934	CLIP-seq
MIRT944087	hsa-miR-4252	CLIP-seq
MIRT944088	hsa-miR-4260	CLIP-seq
MIRT944089	hsa-miR-4265	CLIP-seq
MIRT944091	hsa-miR-4296	CLIP-seq
MIRT944092	hsa-miR-4310	CLIP-seq
MIRT1979557	hsa-miR-4312	CLIP-seq
MIRT944093	hsa-miR-4319	CLIP-seq
MIRT944094	hsa-miR-4322	CLIP-seq
MIRT944095	hsa-miR-4429	CLIP-seq
MIRT1979558	hsa-miR-4436a	CLIP-seq
MIRT944096	hsa-miR-4447	CLIP-seq
MIRT944097	hsa-miR-4472	CLIP-seq
MIRT944098	hsa-miR-4489	CLIP-seq
MIRT944099	hsa-miR-4492	CLIP-seq
MIRT944100	hsa-miR-4498	CLIP-seq
MIRT944101	hsa-miR-4505	CLIP-seq
MIRT1979559	hsa-miR-4514	CLIP-seq
MIRT1979560	hsa-miR-4522	CLIP-seq
MIRT944104	hsa-miR-4639-5p	CLIP-seq
MIRT944106	hsa-miR-4643	CLIP-seq
MIRT1979561	hsa-miR-4652-5p	CLIP-seq
MIRT944108	hsa-miR-4667-5p	CLIP-seq
MIRT944109	hsa-miR-4675	CLIP-seq
MIRT944110	hsa-miR-4689	CLIP-seq
MIRT1979562	hsa-miR-4692	CLIP-seq
MIRT944111	hsa-miR-4700-5p	CLIP-seq
MIRT1979563	hsa-miR-4722-5p	CLIP-seq
MIRT944114	hsa-miR-4741	CLIP-seq
MIRT1979564	hsa-miR-4756-3p	CLIP-seq
MIRT944117	hsa-miR-4784	CLIP-seq
MIRT944118	hsa-miR-491-5p	CLIP-seq
MIRT944119	hsa-miR-550a	CLIP-seq
MIRT944121	hsa-miR-592	CLIP-seq
MIRT944122	hsa-miR-597	CLIP-seq
MIRT944124	hsa-miR-615-5p	CLIP-seq
MIRT944125	hsa-miR-637	CLIP-seq
MIRT944126	hsa-miR-661	CLIP-seq
MIRT944128	hsa-miR-762	CLIP-seq
MIRT1979565	hsa-miR-765	CLIP-seq
MIRT1979566	hsa-miR-940	CLIP-seq
MIRT1979548	hsa-miR-1184	CLIP-seq
MIRT1979549	hsa-miR-1205	CLIP-seq
MIRT944052	hsa-miR-1207-3p	CLIP-seq
MIRT944053	hsa-miR-1224-5p	CLIP-seq
MIRT944054	hsa-miR-1254	CLIP-seq
MIRT1979550	hsa-miR-1286	CLIP-seq
MIRT2214643	hsa-miR-1299	CLIP-seq
MIRT2214644	hsa-miR-1470	CLIP-seq
MIRT2214645	hsa-miR-188-5p	CLIP-seq
MIRT2214646	hsa-miR-1910	CLIP-seq
MIRT944062	hsa-miR-1915	CLIP-seq
MIRT944063	hsa-miR-198	CLIP-seq
MIRT1979551	hsa-miR-22	CLIP-seq
MIRT2214647	hsa-miR-223	CLIP-seq
MIRT2214648	hsa-miR-2355-5p	CLIP-seq
MIRT944064	hsa-miR-2861	CLIP-seq
MIRT944065	hsa-miR-31	CLIP-seq
MIRT944066	hsa-miR-3116	CLIP-seq
MIRT1979552	hsa-miR-3144-5p	CLIP-seq
MIRT944068	hsa-miR-3150b-3p	CLIP-seq
MIRT1979553	hsa-miR-3158-5p	CLIP-seq
MIRT1979554	hsa-miR-3165	CLIP-seq
MIRT944072	hsa-miR-3180-5p	CLIP-seq
MIRT1979555	hsa-miR-3191	CLIP-seq
MIRT944073	hsa-miR-3194-5p	CLIP-seq
MIRT944074	hsa-miR-320a	CLIP-seq
MIRT944075	hsa-miR-320b	CLIP-seq
MIRT944076	hsa-miR-320c	CLIP-seq
MIRT944077	hsa-miR-320d	CLIP-seq
MIRT944080	hsa-miR-3605-3p	CLIP-seq
MIRT944081	hsa-miR-3607-5p	CLIP-seq
MIRT2214649	hsa-miR-3667-3p	CLIP-seq
MIRT944083	hsa-miR-3690	CLIP-seq
MIRT944084	hsa-miR-377	CLIP-seq
MIRT944085	hsa-miR-3915	CLIP-seq
MIRT944086	hsa-miR-3919	CLIP-seq
MIRT1979556	hsa-miR-3934	CLIP-seq
MIRT944087	hsa-miR-4252	CLIP-seq
MIRT944088	hsa-miR-4260	CLIP-seq
MIRT944090	hsa-miR-4292	CLIP-seq
MIRT2214650	hsa-miR-4302	CLIP-seq
MIRT1979557	hsa-miR-4312	CLIP-seq
MIRT944095	hsa-miR-4429	CLIP-seq
MIRT1979558	hsa-miR-4436a	CLIP-seq
MIRT2214651	hsa-miR-4469	CLIP-seq
MIRT944098	hsa-miR-4489	CLIP-seq
MIRT944099	hsa-miR-4492	CLIP-seq
MIRT944100	hsa-miR-4498	CLIP-seq
MIRT944101	hsa-miR-4505	CLIP-seq
MIRT1979559	hsa-miR-4514	CLIP-seq
MIRT2214652	hsa-miR-4520a-3p	CLIP-seq
MIRT1979560	hsa-miR-4522	CLIP-seq
MIRT2214653	hsa-miR-455-3p	CLIP-seq
MIRT944103	hsa-miR-4638-3p	CLIP-seq
MIRT944104	hsa-miR-4639-5p	CLIP-seq
MIRT944106	hsa-miR-4643	CLIP-seq
MIRT1979561	hsa-miR-4652-5p	CLIP-seq
MIRT2214654	hsa-miR-4667-3p	CLIP-seq
MIRT944110	hsa-miR-4689	CLIP-seq
MIRT1979562	hsa-miR-4692	CLIP-seq
MIRT2214655	hsa-miR-4697-3p	CLIP-seq
MIRT1979563	hsa-miR-4722-5p	CLIP-seq
MIRT1979564	hsa-miR-4756-3p	CLIP-seq
MIRT2214656	hsa-miR-4782-5p	CLIP-seq
MIRT944117	hsa-miR-4784	CLIP-seq
MIRT2214657	hsa-miR-4795-5p	CLIP-seq
MIRT2214658	hsa-miR-516b	CLIP-seq
MIRT944119	hsa-miR-550a	CLIP-seq
MIRT944126	hsa-miR-661	CLIP-seq
MIRT944127	hsa-miR-663b	CLIP-seq
MIRT944128	hsa-miR-762	CLIP-seq
MIRT1979565	hsa-miR-765	CLIP-seq
MIRT2214659	hsa-miR-875-3p	CLIP-seq
MIRT1979566	hsa-miR-940	CLIP-seq
MIRT1979551	hsa-miR-22	CLIP-seq
MIRT944072	hsa-miR-3180-5p	CLIP-seq
MIRT944074	hsa-miR-320a	CLIP-seq
MIRT944075	hsa-miR-320b	CLIP-seq
MIRT944076	hsa-miR-320c	CLIP-seq
MIRT944077	hsa-miR-320d	CLIP-seq
MIRT944095	hsa-miR-4429	CLIP-seq
MIRT2214643	hsa-miR-1299	CLIP-seq
MIRT2214659	hsa-miR-875-3p	CLIP-seq
MIRT2519054	hsa-miR-329	CLIP-seq
MIRT2519055	hsa-miR-362-3p	CLIP-seq
MIRT2214650	hsa-miR-4302	CLIP-seq
MIRT2519054	hsa-miR-329	CLIP-seq
MIRT2519055	hsa-miR-362-3p	CLIP-seq
MIRT2214650	hsa-miR-4302	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000506	Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	IDA	10944123, 16162815
GO:0000506	Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	IPI	16162815
GO:0000506	Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	TAS	16280320
GO:0005515	Function	Protein binding	IPI	10835346, 10944123, 16162815
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	16162815
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	NAS	9724629
GO:0005789	Component	Endoplasmic reticulum membrane	TAS	9724629, 16280320
GO:0006486	Process	Protein glycosylation	IEA
GO:0006488	Process	Dolichol-linked oligosaccharide biosynthetic process	IBA
GO:0006506	Process	GPI anchor biosynthetic process	IDA	16162815
GO:0008047	Function	Enzyme activator activity	IDA	10835346
GO:0016020	Component	Membrane	IEA
GO:0030234	Function	Enzyme regulator activity	IBA
GO:0030234	Function	Enzyme regulator activity	IEA
GO:0033185	Component	Dolichol-phosphate-mannose synthase complex	IBA
GO:0033185	Component	Dolichol-phosphate-mannose synthase complex	IDA	10835346
GO:0033185	Component	Dolichol-phosphate-mannose synthase complex	IPI	10835346
GO:0180047	Process	Dolichol phosphate mannose biosynthetic process	IDA	10835346
GO:0180047	Process	Dolichol phosphate mannose biosynthetic process	IEA

Other IDs

• MIM: 603564
• HGNC: 3006
• e!Ensembl: ENSG00000136908

Protein

• UniProt ID: O94777
• Protein name: Dolichol phosphate-mannose biosynthesis regulatory protein (Dolichol-phosphate mannose synthase subunit 2) (DPM synthase subunit 2)
• Protein function: Regulates the biosynthesis of dolichol phosphate-mannose (PubMed:10835346). Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1 (PubMed:10835346). Part of t
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07297	DPM2	5 → 81	Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)	Family

• Sequence:

  MATGTDQVVGLGLVAVSLIIFTYYTAWVILLPFIDSQHVIHKYFLPRAYAVAIPLAAGLL
  LLLFVGLFISYVMLKTKRVTKKAQ

• Sequence length: 84

Pathways

KEGG:

N-Glycan biosynthesis
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
Metabolic pathways

Reactome:

Synthesis of dolichyl-phosphate mannose
Synthesis of glycosylphosphatidylinositol (GPI)
Defective DPM1 causes DPM1-CDG (CDG-1e)
Defective DPM3 causes DPM3-CDG (CDG-1o)
Defective DPM2 causes DPM2-CDG (CDG-1u)

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Congenital muscular dystrophy with intellectual disability and severe epilepsy	Likely pathogenic; Pathogenic	rs549450795, rs1185338798, rs2539553454, rs2539556000, rs2539558352, rs397514503, rs797044467, rs1349389319	RCV001375849 RCV001375850 RCV003150595 RCV003536548 RCV003649640 RCV000032641 RCV000032642 RCV000779570

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
DPM2-related disorder	Likely benign; Benign	rs532790675, rs7042788	RCV004758870 RCV003970243

Associations from Text Mining
Disease Name	Relationship Type	References
Congenital Disorders of Glycosylation	Associate	33129689
Death	Associate	33129689
Developmental Disabilities	Associate	33129689
Early Onset Glaucoma	Associate	33129689
Glycogen Storage Disease XIV	Associate	33129689
Heart Defects Congenital	Associate	33129689
Immunoglobulin G4 Related Disease	Associate	36609529
Intellectual Disability	Associate	33129689
Muscle Hypertonia	Associate	33129689
Muscle Hypotonia	Associate	33129689
Muscle Weakness	Associate	33129689
Muscular Atrophy	Associate	33129689
Seizures	Associate	33129689
Walker Warburg Syndrome	Associate	35932216