Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8804
Gene name Gene Name - the full gene name approved by the HGNC.
Cellular repressor of E1A stimulated genes 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CREG1
Synonyms (NCBI Gene) Gene synonyms aliases
CREG
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q24.2
Summary Summary of gene provided in NCBI Entrez Gene.
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT007367 hsa-miR-31-5p Immunofluorescence, Luciferase reporter assay, qRT-PCR, Western blot 23518389
MIRT028971 hsa-miR-26b-5p Microarray 19088304
MIRT036577 hsa-miR-941 CLASH 23622248
MIRT727936 hsa-miR-15a-5p HITS-CLIP 22473208
MIRT727937 hsa-miR-15b-5p HITS-CLIP 22473208
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003714 Function Transcription corepressor activity TAS 9710587
GO:0005576 Component Extracellular region TAS
GO:0005615 Component Extracellular space IBA 21873635
GO:0005615 Component Extracellular space IDA 25645918
GO:0006357 Process Regulation of transcription by RNA polymerase II TAS 9710587
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618055 2351 ENSG00000143162
Protein
UniProt ID O75629
Protein name Protein CREG1 (Cellular repressor of E1A-stimulated genes 1)
Protein function May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires inte
PDB 1XHN
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13883 Pyrid_oxidase_2 50 216 Domain
Sequence
Sequence length 220
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17013881
Unknown
Disease term Disease name Evidence References Source
Heart failure Heart Failure, Diastolic 29556499 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Atherosclerosis Inhibit 27139506, 32067910
Carcinoma Non Small Cell Lung Associate 26722374
Diabetes Mellitus Type 2 Inhibit 27139506
Endometrial Neoplasms Associate 17451460
Li Fraumeni Syndrome Associate 21263217
Macular Degeneration Associate 39487449
Osteosarcoma Associate 21263217
Uveal melanoma Associate 31903983
Vascular Diseases Associate 32067910