Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8708
Gene name Gene Name - the full gene name approved by the HGNC.	Beta-1,3-galactosyltransferase 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	B3GALT1
Synonyms (NCBI Gene) Gene synonyms aliases	beta3Gal-T1
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q24.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and

Show/Hide all(45)

miRTarBase ID	miRNA	Experiments	Reference
MIRT029959	hsa-miR-26b-5p	Microarray	19088304
MIRT812911	hsa-miR-1184	CLIP-seq
MIRT812912	hsa-miR-1205	CLIP-seq
MIRT812913	hsa-miR-1231	CLIP-seq
MIRT812914	hsa-miR-1252	CLIP-seq
MIRT812915	hsa-miR-1299	CLIP-seq
MIRT812916	hsa-miR-3120-5p	CLIP-seq
MIRT812917	hsa-miR-3158-5p	CLIP-seq
MIRT812918	hsa-miR-3202	CLIP-seq
MIRT812919	hsa-miR-323-3p	CLIP-seq
MIRT812920	hsa-miR-3665	CLIP-seq
MIRT812921	hsa-miR-4318	CLIP-seq
MIRT812922	hsa-miR-4328	CLIP-seq
MIRT812923	hsa-miR-4418	CLIP-seq
MIRT812924	hsa-miR-4533	CLIP-seq
MIRT812925	hsa-miR-4670-5p	CLIP-seq
MIRT812926	hsa-miR-4677-3p	CLIP-seq
MIRT812927	hsa-miR-4691-3p	CLIP-seq
MIRT812928	hsa-miR-4693-5p	CLIP-seq
MIRT812929	hsa-miR-4729	CLIP-seq
MIRT812930	hsa-miR-509-3-5p	CLIP-seq
MIRT812931	hsa-miR-509-5p	CLIP-seq
MIRT812932	hsa-miR-657	CLIP-seq
MIRT812933	hsa-miR-875-3p	CLIP-seq
MIRT812934	hsa-miR-892a	CLIP-seq
MIRT812911	hsa-miR-1184	CLIP-seq
MIRT812912	hsa-miR-1205	CLIP-seq
MIRT812917	hsa-miR-3158-5p	CLIP-seq
MIRT812923	hsa-miR-4418	CLIP-seq
MIRT812927	hsa-miR-4691-3p	CLIP-seq
MIRT812930	hsa-miR-509-3-5p	CLIP-seq
MIRT812931	hsa-miR-509-5p	CLIP-seq
MIRT812911	hsa-miR-1184	CLIP-seq
MIRT812912	hsa-miR-1205	CLIP-seq
MIRT812917	hsa-miR-3158-5p	CLIP-seq
MIRT812923	hsa-miR-4418	CLIP-seq
MIRT812927	hsa-miR-4691-3p	CLIP-seq
MIRT812930	hsa-miR-509-3-5p	CLIP-seq
MIRT812931	hsa-miR-509-5p	CLIP-seq
MIRT1940343	hsa-miR-511	CLIP-seq
MIRT2179247	hsa-miR-3165	CLIP-seq
MIRT1940343	hsa-miR-511	CLIP-seq
MIRT2179248	hsa-miR-518a-5p	CLIP-seq
MIRT2179249	hsa-miR-527	CLIP-seq
MIRT2179250	hsa-miR-548u	CLIP-seq

Show/Hide all(14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005794	Component	Golgi apparatus	IBA	21873635
GO:0006486	Process	Protein glycosylation	IBA	21873635
GO:0006486	Process	Protein glycosylation	IEA
GO:0006682	Process	Galactosylceramide biosynthetic process	IDA	9582303
GO:0008375	Function	Acetylglucosaminyltransferase activity	IBA	21873635
GO:0008376	Function	Acetylgalactosaminyltransferase activity	IBA	21873635
GO:0008499	Function	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	IDA	9582303
GO:0008532	Function	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	IBA	21873635
GO:0009312	Process	Oligosaccharide biosynthetic process	IDA	9582303
GO:0016021	Component	Integral component of membrane	NAS	9582303
GO:0030259	Process	Lipid glycosylation	IDA	9582303
GO:0030311	Process	Poly-N-acetyllactosamine biosynthetic process	IBA	21873635
GO:0047275	Function	Glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity	IEA

MIM	HGNC	e!Ensembl
603093	916	ENSG00000172318

Protein

UniProt ID

Q9Y5Z6

Protein name

Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1)

Protein function

Beta-1,3-galactosyltransferase that transfers galactose from UDP-alpha-D-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycopr

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01762	Galactosyl_T	92 → 283	Galactosyltransferase	Family

Tissue specificity

TISSUE SPECIFICITY: Detected in brain and colon mucosa and to a lesser extent in colon adenocarcinoma cells. {ECO:0000269|PubMed:10356986, ECO:0000269|PubMed:9582303}.

Sequence

MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINP
HSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGK
NADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDI
FVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTG
YIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRV
ITVHQISPEEMHRIWNDMSSKKHLRC

Sequence length

326

Interactions

View interactions

	KEGG		Reactome
	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways		Lewis blood group biosynthesis

Show/Hide Unknown Diseases (3)

Disease term	Disease name	Source
Unknown
Neuroticism	Neuroticism	GWAS
Diabetes	Diabetes	GWAS
Insomnia	Insomnia	GWAS

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Ovarian Epithelial	Associate	33173439
Carcinoma Renal Cell	Associate	36104680
Neoplasms	Associate	36104680

B3GALT1 (beta-1,3-galactosyltransferase 1)