Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8675
Gene name Gene Name - the full gene name approved by the HGNC.
Syntaxin 16
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
STX16
Synonyms (NCBI Gene) Gene synonyms aliases
SYN-16, SYN16
Chromosome Chromosome number
20
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
20q13.32
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking a
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT028613 hsa-miR-30a-5p Proteomics 18668040
MIRT030553 hsa-miR-24-3p Western blot;Other 17150773
MIRT048767 hsa-miR-93-5p CLASH 23622248
MIRT043405 hsa-miR-331-3p CLASH 23622248
MIRT042882 hsa-miR-324-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane TAS
GO:0000149 Function SNARE binding IBA 21873635
GO:0005484 Function SNAP receptor activity IBA 21873635
GO:0005484 Function SNAP receptor activity IDA 15215310
GO:0005515 Function Protein binding IPI 18195106, 25416956, 28626000, 30833792
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603666 11431 ENSG00000124222
Protein
UniProt ID O14662
Protein name Syntaxin-16 (Syn16)
Protein function SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
PDB 8QQF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00804 Syntaxin 78 265 Syntaxin Domain
PF05739 SNARE 266 318 SNARE domain Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous.
Sequence
Sequence length 325
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  SNARE interactions in vesicular transport   Intra-Golgi traffic
Retrograde transport at the Trans-Golgi-Network
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Cataract Cataract rs118203965, rs118203966, rs104893685, rs121908938, rs104894175, rs121909048, rs28937573, rs121909049, rs121909050, rs74315488, rs80358200, rs80358203, rs121434643, rs56141211, rs132630322
View all (150 more)
Diaphyseal dysplasia Camurati-Engelmann Syndrome rs104894719, rs104894720, rs104894721, rs111033611, rs104894722, rs1599893542
Isolated somatotropin deficiency Isolated somatotropin deficiency rs797044450, rs71640277, rs863223306, rs2144738731, rs863223307, rs2144739370, rs863223309, rs863223310, rs137853223, rs2144739380, rs2144739391
Nystagmus Nystagmus rs137852207, rs137852208, rs1928435502, rs137852209, rs137852210, rs1929191668, rs137852211, rs137852212, rs2124209414, rs387906720, rs387906721, rs1602791884, rs786205896
Unknown
Disease term Disease name Evidence References Source
Mental depression Depressive disorder ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Abnormalities Drug Induced Associate 35859320
Alzheimer Disease Associate 28084650, 28711660
Autism Spectrum Disorder Associate 27404287
Calcium Metabolism Disorders Associate 34477200
Gastrointestinal Stromal Tumors Associate 25987131
Heart Failure Associate 35128826
Obesity Associate 28453643
Pseudohypoaldosteronism Associate 25603460, 25997889, 28084650, 33247854, 34477200, 34791361
Pseudohypoparathyroidism Associate 15800843, 20538864, 20965295, 21062889, 23087324, 24438374, 25843330, 26819647, 33247854, 34477200, 39894498
Pseudohypoparathyroidism Type 1B Associate 21062889, 28453643, 34157100, 39894498