Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8650
Gene name Gene Name - the full gene name approved by the HGNC.	NUMB endocytic adaptor protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NUMB
Synonyms (NCBI Gene) Gene synonyms aliases	C14orf41, S171, c14_5527
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q24.2-q24.3
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate w

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004970	hsa-miR-31-5p	Luciferase reporter assay, qRT-PCR	19524507
MIRT019211	hsa-miR-335-5p	Microarray	18185580
MIRT020047	hsa-miR-375	Microarray	20215506
MIRT020360	hsa-miR-29c-3p	Sequencing	20371350
MIRT027189	hsa-miR-103a-3p	Sequencing	20371350
MIRT054669	hsa-miR-146a-5p	Luciferase reporter assay	24092752
MIRT054669	hsa-miR-146a-5p	Luciferase reporter assay	24092752
MIRT547268	hsa-miR-548av-3p	PAR-CLIP	21572407
MIRT547266	hsa-miR-4418	PAR-CLIP	21572407
MIRT547267	hsa-miR-509-3-5p	PAR-CLIP	21572407
MIRT547265	hsa-miR-509-5p	PAR-CLIP	21572407
MIRT547264	hsa-miR-3942-5p	PAR-CLIP	21572407
MIRT547263	hsa-miR-4703-5p	PAR-CLIP	21572407
MIRT547261	hsa-miR-4496	PAR-CLIP	21572407
MIRT547262	hsa-miR-3163	PAR-CLIP	21572407
MIRT547260	hsa-miR-6074	PAR-CLIP	21572407
MIRT547259	hsa-miR-1184	PAR-CLIP	21572407
MIRT547258	hsa-miR-4738-3p	PAR-CLIP	21572407
MIRT027189	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT547257	hsa-miR-107	PAR-CLIP	21572407
MIRT547256	hsa-miR-4684-5p	PAR-CLIP	21572407
MIRT547268	hsa-miR-548av-3p	PAR-CLIP	21572407
MIRT071145	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT547266	hsa-miR-4418	PAR-CLIP	21572407
MIRT547267	hsa-miR-509-3-5p	PAR-CLIP	21572407
MIRT547265	hsa-miR-509-5p	PAR-CLIP	21572407
MIRT547264	hsa-miR-3942-5p	PAR-CLIP	21572407
MIRT547263	hsa-miR-4703-5p	PAR-CLIP	21572407
MIRT547261	hsa-miR-4496	PAR-CLIP	21572407
MIRT547262	hsa-miR-3163	PAR-CLIP	21572407
MIRT547260	hsa-miR-6074	PAR-CLIP	21572407
MIRT547259	hsa-miR-1184	PAR-CLIP	21572407
MIRT547258	hsa-miR-4738-3p	PAR-CLIP	21572407
MIRT027189	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT547257	hsa-miR-107	PAR-CLIP	21572407
MIRT547256	hsa-miR-4684-5p	PAR-CLIP	21572407
MIRT731260	hsa-let-7c-5p	ASANPaCa"	27521217
MIRT731260	hsa-let-7c-5p	ASANPaCa"	27521217
MIRT731352	hsa-miR-34a-5p	Luciferase reporter assay	26849305
MIRT731352	hsa-miR-34a-5p	Luciferase reporter assay	26849305
MIRT734470	hsa-miR-146b-5p	Luciferase reporter assay, Western blotting	32346414
MIRT547268	hsa-miR-548av-3p	PAR-CLIP	21572407
MIRT547266	hsa-miR-4418	PAR-CLIP	21572407
MIRT547267	hsa-miR-509-3-5p	PAR-CLIP	21572407
MIRT547265	hsa-miR-509-5p	PAR-CLIP	21572407
MIRT547264	hsa-miR-3942-5p	PAR-CLIP	21572407
MIRT547263	hsa-miR-4703-5p	PAR-CLIP	21572407
MIRT547261	hsa-miR-4496	PAR-CLIP	21572407
MIRT547262	hsa-miR-3163	PAR-CLIP	21572407
MIRT547260	hsa-miR-6074	PAR-CLIP	21572407
MIRT547259	hsa-miR-1184	PAR-CLIP	21572407
MIRT547258	hsa-miR-4738-3p	PAR-CLIP	21572407
MIRT027189	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT547257	hsa-miR-107	PAR-CLIP	21572407
MIRT547256	hsa-miR-4684-5p	PAR-CLIP	21572407
MIRT547268	hsa-miR-548av-3p	PAR-CLIP	21572407
MIRT071145	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT547266	hsa-miR-4418	PAR-CLIP	21572407
MIRT547267	hsa-miR-509-3-5p	PAR-CLIP	21572407
MIRT547265	hsa-miR-509-5p	PAR-CLIP	21572407
MIRT547264	hsa-miR-3942-5p	PAR-CLIP	21572407
MIRT547263	hsa-miR-4703-5p	PAR-CLIP	21572407
MIRT547261	hsa-miR-4496	PAR-CLIP	21572407
MIRT547262	hsa-miR-3163	PAR-CLIP	21572407
MIRT547260	hsa-miR-6074	PAR-CLIP	21572407
MIRT547259	hsa-miR-1184	PAR-CLIP	21572407
MIRT547258	hsa-miR-4738-3p	PAR-CLIP	21572407
MIRT027189	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT547257	hsa-miR-107	PAR-CLIP	21572407
MIRT547256	hsa-miR-4684-5p	PAR-CLIP	21572407
MIRT755451	hsa-miR-222-5p	Luciferase reporter assay, Western blotting, qRT-PCR	37566749
MIRT1198830	hsa-miR-1205	CLIP-seq
MIRT1198831	hsa-miR-1301	CLIP-seq
MIRT1198832	hsa-miR-2052	CLIP-seq
MIRT1198833	hsa-miR-2115	CLIP-seq
MIRT1198834	hsa-miR-219-5p	CLIP-seq
MIRT1198835	hsa-miR-3120-5p	CLIP-seq
MIRT1198836	hsa-miR-3122	CLIP-seq
MIRT1198837	hsa-miR-3158-5p	CLIP-seq
MIRT1198838	hsa-miR-335	CLIP-seq
MIRT1198839	hsa-miR-346	CLIP-seq
MIRT1198840	hsa-miR-3606	CLIP-seq
MIRT1198841	hsa-miR-3670	CLIP-seq
MIRT1198842	hsa-miR-369-3p	CLIP-seq
MIRT1198843	hsa-miR-374a	CLIP-seq
MIRT1198844	hsa-miR-374b	CLIP-seq
MIRT1198845	hsa-miR-3913-5p	CLIP-seq
MIRT1198846	hsa-miR-410	CLIP-seq
MIRT1198847	hsa-miR-4288	CLIP-seq
MIRT1198848	hsa-miR-4421	CLIP-seq
MIRT1198849	hsa-miR-4433	CLIP-seq
MIRT1198850	hsa-miR-4445	CLIP-seq
MIRT1198851	hsa-miR-4459	CLIP-seq
MIRT1198852	hsa-miR-450b-3p	CLIP-seq
MIRT1198853	hsa-miR-4660	CLIP-seq
MIRT1198854	hsa-miR-4713-3p	CLIP-seq
MIRT1198855	hsa-miR-4753-5p	CLIP-seq
MIRT1198856	hsa-miR-4768-3p	CLIP-seq
MIRT1198857	hsa-miR-4772-3p	CLIP-seq
MIRT1198858	hsa-miR-4778-5p	CLIP-seq
MIRT1198859	hsa-miR-4782-3p	CLIP-seq
MIRT1198860	hsa-miR-485-5p	CLIP-seq
MIRT1198861	hsa-miR-5047	CLIP-seq
MIRT1198862	hsa-miR-508-3p	CLIP-seq
MIRT1198863	hsa-miR-570	CLIP-seq
MIRT1198864	hsa-miR-632	CLIP-seq
MIRT1198865	hsa-miR-769-3p	CLIP-seq
MIRT1198866	hsa-miR-891b	CLIP-seq
MIRT1198867	hsa-miR-921	CLIP-seq
MIRT1198868	hsa-miR-101	CLIP-seq
MIRT1198869	hsa-miR-103a	CLIP-seq
MIRT1198870	hsa-miR-1197	CLIP-seq
MIRT1198830	hsa-miR-1205	CLIP-seq
MIRT1198871	hsa-miR-1231	CLIP-seq
MIRT1198872	hsa-miR-1238	CLIP-seq
MIRT1198873	hsa-miR-1254	CLIP-seq
MIRT1198874	hsa-miR-1271	CLIP-seq
MIRT1198875	hsa-miR-128	CLIP-seq
MIRT1198876	hsa-miR-1285	CLIP-seq
MIRT1198831	hsa-miR-1301	CLIP-seq
MIRT1198877	hsa-miR-1323	CLIP-seq
MIRT1198878	hsa-miR-134	CLIP-seq
MIRT1198879	hsa-miR-182	CLIP-seq
MIRT1198880	hsa-miR-199a-3p	CLIP-seq
MIRT1198881	hsa-miR-199b-3p	CLIP-seq
MIRT1198882	hsa-miR-200b	CLIP-seq
MIRT1198883	hsa-miR-200c	CLIP-seq
MIRT1198832	hsa-miR-2052	CLIP-seq
MIRT1198833	hsa-miR-2115	CLIP-seq
MIRT1198884	hsa-miR-2117	CLIP-seq
MIRT1198834	hsa-miR-219-5p	CLIP-seq
MIRT1198885	hsa-miR-27a	CLIP-seq
MIRT1198886	hsa-miR-27b	CLIP-seq
MIRT1198887	hsa-miR-2861	CLIP-seq
MIRT1198888	hsa-miR-31	CLIP-seq
MIRT1198889	hsa-miR-3116	CLIP-seq
MIRT1198890	hsa-miR-3118	CLIP-seq
MIRT1198835	hsa-miR-3120-5p	CLIP-seq
MIRT1198891	hsa-miR-3121-5p	CLIP-seq
MIRT1198892	hsa-miR-3124-3p	CLIP-seq
MIRT1198893	hsa-miR-3129-5p	CLIP-seq
MIRT1198894	hsa-miR-3140-3p	CLIP-seq
MIRT1198895	hsa-miR-3143	CLIP-seq
MIRT1198837	hsa-miR-3158-5p	CLIP-seq
MIRT1198896	hsa-miR-3159	CLIP-seq
MIRT1198897	hsa-miR-3187-5p	CLIP-seq
MIRT1198898	hsa-miR-326	CLIP-seq
MIRT1198899	hsa-miR-330-5p	CLIP-seq
MIRT1198838	hsa-miR-335	CLIP-seq
MIRT1198900	hsa-miR-339-5p	CLIP-seq
MIRT1198839	hsa-miR-346	CLIP-seq
MIRT1198901	hsa-miR-3591-5p	CLIP-seq
MIRT1198902	hsa-miR-3660	CLIP-seq
MIRT1198903	hsa-miR-3664-5p	CLIP-seq
MIRT1198904	hsa-miR-3690	CLIP-seq
MIRT1198905	hsa-miR-378	CLIP-seq
MIRT1198906	hsa-miR-378b	CLIP-seq
MIRT1198907	hsa-miR-378c	CLIP-seq
MIRT1198908	hsa-miR-378d	CLIP-seq
MIRT1198909	hsa-miR-378e	CLIP-seq
MIRT1198910	hsa-miR-378f	CLIP-seq
MIRT1198911	hsa-miR-378g	CLIP-seq
MIRT1198912	hsa-miR-378h	CLIP-seq
MIRT1198913	hsa-miR-378i	CLIP-seq
MIRT1198914	hsa-miR-3924	CLIP-seq
MIRT1198915	hsa-miR-3943	CLIP-seq
MIRT1198846	hsa-miR-410	CLIP-seq
MIRT1198916	hsa-miR-422a	CLIP-seq
MIRT1198917	hsa-miR-4255	CLIP-seq
MIRT1198918	hsa-miR-4268	CLIP-seq
MIRT1198919	hsa-miR-4273	CLIP-seq
MIRT1198920	hsa-miR-4286	CLIP-seq
MIRT1198847	hsa-miR-4288	CLIP-seq
MIRT1198921	hsa-miR-429	CLIP-seq
MIRT1198922	hsa-miR-4323	CLIP-seq
MIRT1198923	hsa-miR-4326	CLIP-seq
MIRT1198848	hsa-miR-4421	CLIP-seq
MIRT1198849	hsa-miR-4433	CLIP-seq
MIRT1198924	hsa-miR-4436a	CLIP-seq
MIRT1198850	hsa-miR-4445	CLIP-seq
MIRT1198925	hsa-miR-4448	CLIP-seq
MIRT1198851	hsa-miR-4459	CLIP-seq
MIRT1198926	hsa-miR-4486	CLIP-seq
MIRT1198927	hsa-miR-4526	CLIP-seq
MIRT1198928	hsa-miR-4640-3p	CLIP-seq
MIRT1198853	hsa-miR-4660	CLIP-seq
MIRT1198854	hsa-miR-4713-3p	CLIP-seq
MIRT1198929	hsa-miR-4714-3p	CLIP-seq
MIRT1198930	hsa-miR-4714-5p	CLIP-seq
MIRT1198931	hsa-miR-4724-3p	CLIP-seq
MIRT1198932	hsa-miR-4742-3p	CLIP-seq
MIRT1198856	hsa-miR-4768-3p	CLIP-seq
MIRT1198857	hsa-miR-4772-3p	CLIP-seq
MIRT1198859	hsa-miR-4782-3p	CLIP-seq
MIRT1198933	hsa-miR-4803	CLIP-seq
MIRT1198860	hsa-miR-485-5p	CLIP-seq
MIRT1198934	hsa-miR-502-5p	CLIP-seq
MIRT1198861	hsa-miR-5047	CLIP-seq
MIRT1198862	hsa-miR-508-3p	CLIP-seq
MIRT1198935	hsa-miR-548aa	CLIP-seq
MIRT1198936	hsa-miR-548ae	CLIP-seq
MIRT1198937	hsa-miR-548aj	CLIP-seq
MIRT1198938	hsa-miR-548am	CLIP-seq
MIRT1198939	hsa-miR-548o	CLIP-seq
MIRT1198940	hsa-miR-548x	CLIP-seq
MIRT1198863	hsa-miR-570	CLIP-seq
MIRT1198941	hsa-miR-612	CLIP-seq
MIRT1198864	hsa-miR-632	CLIP-seq
MIRT1198866	hsa-miR-891b	CLIP-seq
MIRT1198942	hsa-miR-936	CLIP-seq
MIRT1198943	hsa-miR-943	CLIP-seq
MIRT1198944	hsa-miR-96	CLIP-seq
MIRT1198830	hsa-miR-1205	CLIP-seq
MIRT1198872	hsa-miR-1238	CLIP-seq
MIRT2057626	hsa-miR-1273f	CLIP-seq
MIRT1198831	hsa-miR-1301	CLIP-seq
MIRT2057627	hsa-miR-143	CLIP-seq
MIRT1198880	hsa-miR-199a-3p	CLIP-seq
MIRT1198881	hsa-miR-199b-3p	CLIP-seq
MIRT1198833	hsa-miR-2115	CLIP-seq
MIRT1198834	hsa-miR-219-5p	CLIP-seq
MIRT1198835	hsa-miR-3120-5p	CLIP-seq
MIRT1198892	hsa-miR-3124-3p	CLIP-seq
MIRT1198893	hsa-miR-3129-5p	CLIP-seq
MIRT1198894	hsa-miR-3140-3p	CLIP-seq
MIRT1198837	hsa-miR-3158-5p	CLIP-seq
MIRT2057628	hsa-miR-340	CLIP-seq
MIRT1198839	hsa-miR-346	CLIP-seq
MIRT1198902	hsa-miR-3660	CLIP-seq
MIRT2057629	hsa-miR-3662	CLIP-seq
MIRT2057630	hsa-miR-3663-3p	CLIP-seq
MIRT1198841	hsa-miR-3670	CLIP-seq
MIRT1198914	hsa-miR-3924	CLIP-seq
MIRT1198846	hsa-miR-410	CLIP-seq
MIRT1198847	hsa-miR-4288	CLIP-seq
MIRT2057631	hsa-miR-4293	CLIP-seq
MIRT1198848	hsa-miR-4421	CLIP-seq
MIRT1198850	hsa-miR-4445	CLIP-seq
MIRT2057632	hsa-miR-4446-5p	CLIP-seq
MIRT1198927	hsa-miR-4526	CLIP-seq
MIRT1198853	hsa-miR-4660	CLIP-seq
MIRT2057633	hsa-miR-4708-5p	CLIP-seq
MIRT1198854	hsa-miR-4713-3p	CLIP-seq
MIRT1198855	hsa-miR-4753-5p	CLIP-seq
MIRT2057634	hsa-miR-4770	CLIP-seq
MIRT1198859	hsa-miR-4782-3p	CLIP-seq
MIRT2057635	hsa-miR-485-3p	CLIP-seq
MIRT1198861	hsa-miR-5047	CLIP-seq
MIRT2057636	hsa-miR-513a-3p	CLIP-seq
MIRT2057637	hsa-miR-548a-5p	CLIP-seq
MIRT2057638	hsa-miR-548ab	CLIP-seq
MIRT2057639	hsa-miR-548ak	CLIP-seq
MIRT2057640	hsa-miR-548b-5p	CLIP-seq
MIRT2057641	hsa-miR-548c-3p	CLIP-seq
MIRT2057642	hsa-miR-548c-5p	CLIP-seq
MIRT2057643	hsa-miR-548d-5p	CLIP-seq
MIRT2057644	hsa-miR-548h	CLIP-seq
MIRT2057645	hsa-miR-548i	CLIP-seq
MIRT2057646	hsa-miR-548j	CLIP-seq
MIRT2057647	hsa-miR-548n	CLIP-seq
MIRT2057648	hsa-miR-548w	CLIP-seq
MIRT2057649	hsa-miR-548y	CLIP-seq
MIRT2057650	hsa-miR-556-5p	CLIP-seq
MIRT2057651	hsa-miR-559	CLIP-seq
MIRT1198864	hsa-miR-632	CLIP-seq
MIRT1198942	hsa-miR-936	CLIP-seq
MIRT1198834	hsa-miR-219-5p	CLIP-seq
MIRT2286000	hsa-miR-2355-5p	CLIP-seq
MIRT1198846	hsa-miR-410	CLIP-seq
MIRT1198850	hsa-miR-4445	CLIP-seq
MIRT1198859	hsa-miR-4782-3p	CLIP-seq
MIRT2057641	hsa-miR-548c-3p	CLIP-seq
MIRT1198870	hsa-miR-1197	CLIP-seq
MIRT2286001	hsa-miR-1275	CLIP-seq
MIRT1198835	hsa-miR-3120-5p	CLIP-seq
MIRT2286002	hsa-miR-4260	CLIP-seq
MIRT2286003	hsa-miR-4271	CLIP-seq
MIRT1198848	hsa-miR-4421	CLIP-seq
MIRT2286004	hsa-miR-4525	CLIP-seq
MIRT2286005	hsa-miR-4665-5p	CLIP-seq
MIRT2286006	hsa-miR-4723-5p	CLIP-seq
MIRT2286007	hsa-miR-4725-3p	CLIP-seq
MIRT2286008	hsa-miR-625	CLIP-seq
MIRT2583935	hsa-miR-1202	CLIP-seq
MIRT1198830	hsa-miR-1205	CLIP-seq
MIRT1198872	hsa-miR-1238	CLIP-seq
MIRT2583936	hsa-miR-1257	CLIP-seq
MIRT2583937	hsa-miR-125a-3p	CLIP-seq
MIRT2583938	hsa-miR-1267	CLIP-seq
MIRT1198874	hsa-miR-1271	CLIP-seq
MIRT1198831	hsa-miR-1301	CLIP-seq
MIRT2583939	hsa-miR-146a	CLIP-seq
MIRT1198879	hsa-miR-182	CLIP-seq
MIRT2583940	hsa-miR-1827	CLIP-seq
MIRT1198880	hsa-miR-199a-3p	CLIP-seq
MIRT1198881	hsa-miR-199b-3p	CLIP-seq
MIRT1198882	hsa-miR-200b	CLIP-seq
MIRT1198883	hsa-miR-200c	CLIP-seq
MIRT1198833	hsa-miR-2115	CLIP-seq
MIRT2583941	hsa-miR-218	CLIP-seq
MIRT1198834	hsa-miR-219-5p	CLIP-seq
MIRT2583942	hsa-miR-3119	CLIP-seq
MIRT1198835	hsa-miR-3120-5p	CLIP-seq
MIRT1198892	hsa-miR-3124-3p	CLIP-seq
MIRT1198893	hsa-miR-3129-5p	CLIP-seq
MIRT1198894	hsa-miR-3140-3p	CLIP-seq
MIRT2583943	hsa-miR-3152-5p	CLIP-seq
MIRT1198837	hsa-miR-3158-5p	CLIP-seq
MIRT2583944	hsa-miR-3183	CLIP-seq
MIRT2583945	hsa-miR-3200-5p	CLIP-seq
MIRT1198839	hsa-miR-346	CLIP-seq
MIRT2583946	hsa-miR-3612	CLIP-seq
MIRT2583947	hsa-miR-3665	CLIP-seq
MIRT2583948	hsa-miR-3673	CLIP-seq
MIRT1198914	hsa-miR-3924	CLIP-seq
MIRT2583949	hsa-miR-3942-3p	CLIP-seq
MIRT1198915	hsa-miR-3943	CLIP-seq
MIRT2583950	hsa-miR-3972	CLIP-seq
MIRT2583951	hsa-miR-3977	CLIP-seq
MIRT2583952	hsa-miR-4251	CLIP-seq
MIRT1198847	hsa-miR-4288	CLIP-seq
MIRT1198921	hsa-miR-429	CLIP-seq
MIRT1198922	hsa-miR-4323	CLIP-seq
MIRT2583953	hsa-miR-4329	CLIP-seq
MIRT1198848	hsa-miR-4421	CLIP-seq
MIRT2583954	hsa-miR-4423-5p	CLIP-seq
MIRT1198924	hsa-miR-4436a	CLIP-seq
MIRT1198850	hsa-miR-4445	CLIP-seq
MIRT1198851	hsa-miR-4459	CLIP-seq
MIRT2583955	hsa-miR-4464	CLIP-seq
MIRT1198853	hsa-miR-4660	CLIP-seq
MIRT2583956	hsa-miR-4695-5p	CLIP-seq
MIRT1198854	hsa-miR-4713-3p	CLIP-seq
MIRT2583957	hsa-miR-4723-3p	CLIP-seq
MIRT1198931	hsa-miR-4724-3p	CLIP-seq
MIRT2583958	hsa-miR-4736	CLIP-seq
MIRT2583959	hsa-miR-4748	CLIP-seq
MIRT1198855	hsa-miR-4753-5p	CLIP-seq
MIRT2583960	hsa-miR-4756-3p	CLIP-seq
MIRT2583961	hsa-miR-4774-3p	CLIP-seq
MIRT1198859	hsa-miR-4782-3p	CLIP-seq
MIRT2583962	hsa-miR-4790-3p	CLIP-seq
MIRT2583963	hsa-miR-4799-5p	CLIP-seq
MIRT2057635	hsa-miR-485-3p	CLIP-seq
MIRT1198861	hsa-miR-5047	CLIP-seq
MIRT1198862	hsa-miR-508-3p	CLIP-seq
MIRT2583964	hsa-miR-516a-3p	CLIP-seq
MIRT1198935	hsa-miR-548aa	CLIP-seq
MIRT2057641	hsa-miR-548c-3p	CLIP-seq
MIRT1198863	hsa-miR-570	CLIP-seq
MIRT2583965	hsa-miR-578	CLIP-seq
MIRT2583966	hsa-miR-589	CLIP-seq
MIRT2583967	hsa-miR-600	CLIP-seq
MIRT1198864	hsa-miR-632	CLIP-seq
MIRT2583968	hsa-miR-636	CLIP-seq
MIRT2583969	hsa-miR-650	CLIP-seq
MIRT2583970	hsa-miR-889	CLIP-seq
MIRT1198942	hsa-miR-936	CLIP-seq
MIRT2583971	hsa-miR-940	CLIP-seq
MIRT1198944	hsa-miR-96	CLIP-seq
MIRT2583935	hsa-miR-1202	CLIP-seq
MIRT1198830	hsa-miR-1205	CLIP-seq
MIRT1198872	hsa-miR-1238	CLIP-seq
MIRT2583936	hsa-miR-1257	CLIP-seq
MIRT2583937	hsa-miR-125a-3p	CLIP-seq
MIRT2583938	hsa-miR-1267	CLIP-seq
MIRT1198874	hsa-miR-1271	CLIP-seq
MIRT1198831	hsa-miR-1301	CLIP-seq
MIRT2583939	hsa-miR-146a	CLIP-seq
MIRT1198879	hsa-miR-182	CLIP-seq
MIRT2583940	hsa-miR-1827	CLIP-seq
MIRT1198880	hsa-miR-199a-3p	CLIP-seq
MIRT1198881	hsa-miR-199b-3p	CLIP-seq
MIRT1198833	hsa-miR-2115	CLIP-seq
MIRT2583941	hsa-miR-218	CLIP-seq
MIRT1198888	hsa-miR-31	CLIP-seq
MIRT1198835	hsa-miR-3120-5p	CLIP-seq
MIRT1198892	hsa-miR-3124-3p	CLIP-seq
MIRT1198893	hsa-miR-3129-5p	CLIP-seq
MIRT2583943	hsa-miR-3152-5p	CLIP-seq
MIRT1198837	hsa-miR-3158-5p	CLIP-seq
MIRT2583944	hsa-miR-3183	CLIP-seq
MIRT2583945	hsa-miR-3200-5p	CLIP-seq
MIRT1198839	hsa-miR-346	CLIP-seq
MIRT2583946	hsa-miR-3612	CLIP-seq
MIRT2583947	hsa-miR-3665	CLIP-seq
MIRT2583948	hsa-miR-3673	CLIP-seq
MIRT1198914	hsa-miR-3924	CLIP-seq
MIRT2583949	hsa-miR-3942-3p	CLIP-seq
MIRT1198915	hsa-miR-3943	CLIP-seq
MIRT2583950	hsa-miR-3972	CLIP-seq
MIRT2583951	hsa-miR-3977	CLIP-seq
MIRT2583952	hsa-miR-4251	CLIP-seq
MIRT1198847	hsa-miR-4288	CLIP-seq
MIRT1198922	hsa-miR-4323	CLIP-seq
MIRT2583953	hsa-miR-4329	CLIP-seq
MIRT1198848	hsa-miR-4421	CLIP-seq
MIRT2583954	hsa-miR-4423-5p	CLIP-seq
MIRT1198851	hsa-miR-4459	CLIP-seq
MIRT2583955	hsa-miR-4464	CLIP-seq
MIRT1198853	hsa-miR-4660	CLIP-seq
MIRT2583956	hsa-miR-4695-5p	CLIP-seq
MIRT1198854	hsa-miR-4713-3p	CLIP-seq
MIRT2583957	hsa-miR-4723-3p	CLIP-seq
MIRT1198931	hsa-miR-4724-3p	CLIP-seq
MIRT2583958	hsa-miR-4736	CLIP-seq
MIRT2583959	hsa-miR-4748	CLIP-seq
MIRT2583961	hsa-miR-4774-3p	CLIP-seq
MIRT2583962	hsa-miR-4790-3p	CLIP-seq
MIRT2057635	hsa-miR-485-3p	CLIP-seq
MIRT1198861	hsa-miR-5047	CLIP-seq
MIRT2583964	hsa-miR-516a-3p	CLIP-seq
MIRT1198935	hsa-miR-548aa	CLIP-seq
MIRT1198863	hsa-miR-570	CLIP-seq
MIRT2583965	hsa-miR-578	CLIP-seq
MIRT2583966	hsa-miR-589	CLIP-seq
MIRT2583967	hsa-miR-600	CLIP-seq
MIRT1198864	hsa-miR-632	CLIP-seq
MIRT2583968	hsa-miR-636	CLIP-seq
MIRT2583969	hsa-miR-650	CLIP-seq
MIRT2583970	hsa-miR-889	CLIP-seq
MIRT1198942	hsa-miR-936	CLIP-seq
MIRT2583971	hsa-miR-940	CLIP-seq
MIRT1198944	hsa-miR-96	CLIP-seq
MIRT2057641	hsa-miR-548c-3p	CLIP-seq

Show/Hide all(38)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16273093, 17203073, 18172499, 23211419, 24336247, 24561623, 32814053, 35044719, 35384245, 37219487
GO:0005737	Component	Cytoplasm	IBA
GO:0005768	Component	Endosome	IEA
GO:0005769	Component	Early endosome	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005905	Component	Clathrin-coated pit	IEA
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0007399	Process	Nervous system development	IEA
GO:0007399	Process	Nervous system development	IEA
GO:0007405	Process	Neuroblast proliferation	IEA
GO:0007409	Process	Axonogenesis	IEA
GO:0008013	Function	Beta-catenin binding	IEA
GO:0010008	Component	Endosome membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0016323	Component	Basolateral plasma membrane	IBA
GO:0016323	Component	Basolateral plasma membrane	IEA
GO:0021670	Process	Lateral ventricle development	IEA
GO:0021670	Process	Lateral ventricle development	ISS
GO:0021849	Process	Neuroblast division in subventricular zone	IEA
GO:0021849	Process	Neuroblast division in subventricular zone	ISS
GO:0030136	Component	Clathrin-coated vesicle	IDA	19581412
GO:0030335	Process	Positive regulation of cell migration	IGI	19581412
GO:0030335	Process	Positive regulation of cell migration	IMP	19581412
GO:0030900	Process	Forebrain development	IEA
GO:0031410	Component	Cytoplasmic vesicle	IBA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0034332	Process	Adherens junction organization	IEA
GO:0045177	Component	Apical part of cell	IEA
GO:0045294	Function	Alpha-catenin binding	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045296	Function	Cadherin binding	IEA
GO:0050769	Process	Positive regulation of neurogenesis	IBA
GO:0050769	Process	Positive regulation of neurogenesis	IEA
GO:0050769	Process	Positive regulation of neurogenesis	ISS
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099149	Process	Regulation of postsynaptic neurotransmitter receptor internalization	IEA
GO:1903077	Process	Negative regulation of protein localization to plasma membrane	IMP	19581412

MIM	HGNC	e!Ensembl
603728	8060	ENSG00000133961

Protein

UniProt ID

P49757

Protein name

Protein numb homolog (h-Numb) (Protein S171)

Protein function

Regulates clathrin-mediated receptor endocytosis (PubMed:18657069). Plays a role in the process of neurogenesis (By similarity). Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs

PDB

5NJJ , 5NJK

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00640	PID	39 → 172	Phosphotyrosine interaction domain (PTB/PID)	Domain
PF06311	NumbF	258 → 338	NUMB domain	Family

Sequence

MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS
SPTSPTSDATTSLEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
LPSTMQRKTDFPIKNAVPEVEGEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ
SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS
SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQASAAPLQPVLQPPPPTAISQPAS
PFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPYPAPNVPVVGITPSQMVANVFG
TAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASA
DRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL

Sequence length

651

Interactions

View interactions

	KEGG		Reactome
	Notch signaling pathway		Recycling pathway of L1 Degradation of GLI1 by the proteasome Hedgehog 'on' state

NUMB (NUMB endocytic adaptor protein)