Gene Gene information from NCBI Gene database.
Entrez ID 8629
Gene name Jrk helix-turn-helix protein
Gene symbol JRK
Synonyms (NCBI Gene)
JH8jerky
Chromosome 8
Chromosome location 8q24.3
Summary This gene encodes a conserved protein that is similar to DNA-binding proteins, such as major centromere autoantigen B (CENPB). Inactivation of the related gene in mice resulted in epileptic seizures. Childhood Absence Epilepsy (CAE) has been mapped to the
miRNA miRNA information provided by mirtarbase database.
932
miRTarBase ID miRNA Experiments Reference
MIRT1077647 hsa-miR-106a CLIP-seq
MIRT1077648 hsa-miR-106b CLIP-seq
MIRT1077649 hsa-miR-10a CLIP-seq
MIRT1077650 hsa-miR-10b CLIP-seq
MIRT1077651 hsa-miR-1184 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
GO ID Ontology Definition Evidence Reference
GO:0003676 Function Nucleic acid binding IEA
GO:0003677 Function DNA binding IBA
GO:0003677 Function DNA binding IEA
GO:0003729 Function MRNA binding IEA
GO:0005515 Function Protein binding IPI 21399610, 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603210 6199 ENSG00000234616
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75564
Protein name Jerky protein homolog
Protein function May bind DNA.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04218 CENP-B_N 14 66 CENP-B N-terminal DNA-binding domain Domain
PF03221 HTH_Tnp_Tc5 86 149 Tc5 transposase DNA-binding domain Domain
PF03184 DDE_1 213 382 DDE superfamily endonuclease Family
Tissue specificity TISSUE SPECIFICITY: Expressed ubiquitously. {ECO:0000269|PubMed:9675132}.
Sequence
MASKPAAGKSRGEKRKRVVLTLKEKIDICTRLEKGESRKALMQEYNVGMSTLYDIRAHKA
QLLRFF
ASSDSNKALEQRRTLHTPKLEHLDRVLYEWFLGKRSEGVPVSGPMLIEKAKDFY
EQMQLTEPCVFSGGWLWRFKARHGIKKLD
ASSEKQSADHQAAEQFCAFFRSLAAEHGLSA
EQVYNADETGLFWRCLPNPTPEGGAVPGPKQGKDRLTVLMCANATGSHRLKPLAIGKCSG
PRAFKGIQHLPVAYKAQGNAWVDKEIFSDWFHHIFVPSVREHFRTIGLPEDSKAVLLLDS
SRAHPQEAELVSSNVFTIFLPASVASLVQPMEQGIRRDFMRNFINPPVPLQGPHARYNMN
DAIFSVACAWNAVPSHVFRRAW
RKLWPSVAFAEGSSSEEELEAECFPVKPHNKSFAHILE
LVKEGSSCPGQLRQRQAASWGVAGREAEGGRPPAATSPAEVVWSSEKTPKADQDGRGDPG
EGEEVAWEQAAVAFDAVLRFAERQPCFSAQEVGQLRALRAVFRSQQQETVGLEDVVVTSP
EELAIPKCCLEASTET
Sequence length 556
Interactions View interactions