Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8614
Gene name Gene Name - the full gene name approved by the HGNC.
Stanniocalcin 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
STC2
Synonyms (NCBI Gene) Gene synonyms aliases
STC-2, STCRP
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q35.2
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022465 hsa-miR-124-3p Microarray 18668037
MIRT027537 hsa-miR-98-5p Microarray 19088304
MIRT028041 hsa-miR-93-5p Sequencing 20371350
MIRT046093 hsa-miR-125b-5p CLASH 23622248
MIRT438359 hsa-miR-206 qRT-PCR 24855559
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005179 Function Hormone activity IEA
GO:0005615 Component Extracellular space HDA 16502470
GO:0005615 Component Extracellular space IBA 21873635
GO:0005783 Component Endoplasmic reticulum IDA 22503972
GO:0005788 Component Endoplasmic reticulum lumen TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603665 11374 ENSG00000113739
Protein
UniProt ID O76061
Protein name Stanniocalcin-2 (STC-2) (Stanniocalcin-related protein) (STC-related protein) (STCRP)
Protein function Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
PDB 7Y5Q , 8A7D , 8A7E , 8HGH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03298 Stanniocalcin 12 215 Stanniocalcin family Family
Tissue specificity TISSUE SPECIFICITY: Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes.
Sequence
Sequence length 302
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
18492817
Breast carcinoma Breast Carcinoma rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451
View all (71 more)
18492817
Marfan syndrome Mammary Carcinoma, Human rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465
View all (942 more)
18492817
Unknown
Disease term Disease name Evidence References Source
Endometriosis Endometriosis 20864642 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Acquired ichthyosis Associate 36303457
Adenocarcinoma Associate 35109912
Arthritis Rheumatoid Associate 27141097
Atherosclerosis Associate 31173256
Biliary Tract Diseases Associate 33234031
Breast Neoplasms Associate 15546506, 24505115, 27556857, 29593009
Breast Neoplasms Stimulate 29956502
Breast Neoplasms Male Stimulate 29956502
Carcinogenesis Stimulate 22094876
Carcinogenesis Associate 31173256