Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
85463
Gene name Gene Name - the full gene name approved by the HGNC.
Zinc finger CCCH-type containing 12C
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZC3H12C
Synonyms (NCBI Gene) Gene synonyms aliases
MCPIP3
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q22.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020100 hsa-miR-361-5p Sequencing 20371350
MIRT026502 hsa-miR-192-5p Microarray 19074876
MIRT028024 hsa-miR-93-5p Sequencing 20371350
MIRT028230 hsa-miR-33a-5p Sequencing 20371350
MIRT049897 hsa-miR-31-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0003729 Function MRNA binding IBA 21873635
GO:0004521 Function Endoribonuclease activity IBA 21873635
GO:0005515 Function Protein binding IPI 32296183
GO:0005575 Component Cellular_component ND
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
615001 29362 ENSG00000149289
Protein
UniProt ID Q9C0D7
Protein name Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C)
Protein function May function as RNase and regulate the levels of target RNA species.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF18039 UBA_6 162 203 UBA-like domain Domain
PF11977 RNase_Zc3h12a 244 400 Zc3h12a-like Ribonuclease NYN domain Domain
PF18561 Regnase_1_C 833 878 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Domain
Sequence
MPGGGSQEYGVLCIQEYRKNSKVESSTRNNFMGLKDHLGHDLGHLYVESTDPQLSPAVPW
STVENPSMDTVNVGKDEKEASEENASSGDSEENTNSDHESEQLGSISVEPGLITKTHRQL
CRSPCLEPHILKRNEILQDFKPEESQTTSKEAKKPPDVVREYQTKLEFALKLGYSEEQVQ
LVLNKLGTDALINDILGELVKLG
NKSEADQTVSTINTITRETSSLESQRSESPMQEIVTD
DGENLRPIVIDGSNVAMSHGNKEVFSCRGIKLAVDWFLERGHKDITVFVPAWRKEQSRPD
ALITDQEILRKLEKEKILVFTPSRRVQGRRVVCYDDRFIVKLAFESDGIIVSNDNYRDLA
NEKPEWKKFIDERLLMYSFVNDKFMPPDDPLGRHGPSLDN
FLRKKPIVPEHKKQPCPYGK
KCTYGHKCKYYHPERGSQPQRSVADELRAMSRNTAAKTANEGGLVKSNSVPCSTKADSTS
DVKRGAPKRQSDPSIRTQVYQDLEEKLPTKNKLETRSVPSLVSIPATSTAKPQSTTSLSN
GLPSGVHFPPQDQRPQGQYPSMMMATKNHGTPMPYEQYPKCDSPVDIGYYSMLNAYSNLS
LSGPRSPERRFSLDTDYRISSVASDCSSEGSMSCGSSDSYVGYNDRSYVSSPDPQLEENL
KCQHMHPHSRLNPQPFLQNFHDPLTRGQSYSHEEPKFHHKPPLPHLALHLPHSAVGARSS
CPGDYPSPPSSAHSKAPHLGRSLVATRIDSISDSRLYDSSPSRQRKPYSRQEGLGSWERP
GYGIDAYGYRQTYSLPDNSTQPCYEQFTFQSLPEQQEPAWRIPYCGMPQDPPRYQDNREK
IYINLCNIFPPDLVRIVMKRNPHMTDAQQLAAAILVEK
SQLGY
Sequence length 883
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Psoriasis Psoriasis rs281875215, rs587777763, rs281875213, rs281875212 23143594
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 32087603
Alzheimer Disease Associate 25391383
Carcinoma Renal Cell Associate 35795311
Colorectal Neoplasms Inhibit 29751537
Colorectal Neoplasms Associate 34080453, 38267865
Inflammation Inhibit 23360436
Inflammation Associate 35795311
Neoplasm Metastasis Associate 38267865
Neoplasms Inhibit 29751537
Neoplasms Associate 35795311