Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	85461
Gene name Gene Name - the full gene name approved by the HGNC.	Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TANC1
Synonyms (NCBI Gene) Gene synonyms aliases	ROLSB, TANC
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q24.2

Show/Hide all(6)

SNP ID	Visualize variation	Clinical significance	Consequence
rs264588	C>A,T	Drug-response	Intron variant, genic upstream transcript variant
rs264631	C>G	Drug-response	Intron variant, genic upstream transcript variant, genic downstream transcript variant
rs264651	A>G	Drug-response	Intron variant, genic upstream transcript variant
rs6432512	C>T	Drug-response	Genic upstream transcript variant, 5 prime UTR variant, intron variant
rs7582141	G>T	Drug-response	Genic upstream transcript variant, intron variant
rs10497203	A>C	Drug-response	Intron variant, genic upstream transcript variant

Show/Hide all(319)

miRTarBase ID	miRNA	Experiments	Reference
MIRT085871	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT085867	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT085871	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT085866	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT085879	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT085868	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT085888	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT085867	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT1410252	hsa-miR-101	CLIP-seq
MIRT1410253	hsa-miR-106a	CLIP-seq
MIRT1410254	hsa-miR-106b	CLIP-seq
MIRT1410255	hsa-miR-1206	CLIP-seq
MIRT1410256	hsa-miR-1244	CLIP-seq
MIRT1410257	hsa-miR-1255a	CLIP-seq
MIRT1410258	hsa-miR-1255b	CLIP-seq
MIRT1410259	hsa-miR-127-5p	CLIP-seq
MIRT1410260	hsa-miR-1279	CLIP-seq
MIRT1410261	hsa-miR-129-5p	CLIP-seq
MIRT1410262	hsa-miR-130a	CLIP-seq
MIRT1410263	hsa-miR-130b	CLIP-seq
MIRT1410264	hsa-miR-134	CLIP-seq
MIRT1410265	hsa-miR-142-5p	CLIP-seq
MIRT1410266	hsa-miR-144	CLIP-seq
MIRT1410267	hsa-miR-148a	CLIP-seq
MIRT1410268	hsa-miR-148b	CLIP-seq
MIRT1410269	hsa-miR-152	CLIP-seq
MIRT1410270	hsa-miR-17	CLIP-seq
MIRT1410271	hsa-miR-199a-3p	CLIP-seq
MIRT1410272	hsa-miR-199b-3p	CLIP-seq
MIRT1410273	hsa-miR-20a	CLIP-seq
MIRT1410274	hsa-miR-20b	CLIP-seq
MIRT1410275	hsa-miR-298	CLIP-seq
MIRT1410276	hsa-miR-29a	CLIP-seq
MIRT1410277	hsa-miR-29b	CLIP-seq
MIRT1410278	hsa-miR-29c	CLIP-seq
MIRT1410279	hsa-miR-301a	CLIP-seq
MIRT1410280	hsa-miR-301b	CLIP-seq
MIRT1410281	hsa-miR-302a	CLIP-seq
MIRT1410282	hsa-miR-302b	CLIP-seq
MIRT1410283	hsa-miR-302c	CLIP-seq
MIRT1410284	hsa-miR-302d	CLIP-seq
MIRT1410285	hsa-miR-302e	CLIP-seq
MIRT1410286	hsa-miR-3074-3p	CLIP-seq
MIRT1410287	hsa-miR-3118	CLIP-seq
MIRT1410288	hsa-miR-3129-5p	CLIP-seq
MIRT1410289	hsa-miR-3143	CLIP-seq
MIRT1410290	hsa-miR-3148	CLIP-seq
MIRT1410291	hsa-miR-3157-3p	CLIP-seq
MIRT1410292	hsa-miR-3163	CLIP-seq
MIRT1410293	hsa-miR-3170	CLIP-seq
MIRT1410294	hsa-miR-323b-3p	CLIP-seq
MIRT1410295	hsa-miR-329	CLIP-seq
MIRT1410296	hsa-miR-338-3p	CLIP-seq
MIRT1410297	hsa-miR-3609	CLIP-seq
MIRT1410298	hsa-miR-362-3p	CLIP-seq
MIRT1410299	hsa-miR-3646	CLIP-seq
MIRT1410300	hsa-miR-3666	CLIP-seq
MIRT1410301	hsa-miR-3688-3p	CLIP-seq
MIRT1410302	hsa-miR-372	CLIP-seq
MIRT1410303	hsa-miR-373	CLIP-seq
MIRT1410304	hsa-miR-3919	CLIP-seq
MIRT1410305	hsa-miR-3925-5p	CLIP-seq
MIRT1410306	hsa-miR-3944-5p	CLIP-seq
MIRT1410307	hsa-miR-4276	CLIP-seq
MIRT1410308	hsa-miR-4295	CLIP-seq
MIRT1410309	hsa-miR-4432	CLIP-seq
MIRT1410310	hsa-miR-452	CLIP-seq
MIRT1410311	hsa-miR-454	CLIP-seq
MIRT1410312	hsa-miR-4676-3p	CLIP-seq
MIRT1410313	hsa-miR-4703-3p	CLIP-seq
MIRT1410314	hsa-miR-4719	CLIP-seq
MIRT1410315	hsa-miR-4720-3p	CLIP-seq
MIRT1410316	hsa-miR-4760-5p	CLIP-seq
MIRT1410317	hsa-miR-4774-5p	CLIP-seq
MIRT1410318	hsa-miR-4778-5p	CLIP-seq
MIRT1410319	hsa-miR-4796-3p	CLIP-seq
MIRT1410320	hsa-miR-4797-5p	CLIP-seq
MIRT1410321	hsa-miR-4804-3p	CLIP-seq
MIRT1410322	hsa-miR-490-5p	CLIP-seq
MIRT1410323	hsa-miR-499-5p	CLIP-seq
MIRT1410324	hsa-miR-512-3p	CLIP-seq
MIRT1410325	hsa-miR-513b	CLIP-seq
MIRT1410326	hsa-miR-519d	CLIP-seq
MIRT1410327	hsa-miR-520a-3p	CLIP-seq
MIRT1410328	hsa-miR-520b	CLIP-seq
MIRT1410329	hsa-miR-520c-3p	CLIP-seq
MIRT1410330	hsa-miR-520d-3p	CLIP-seq
MIRT1410331	hsa-miR-520e	CLIP-seq
MIRT1410332	hsa-miR-548ah	CLIP-seq
MIRT1410333	hsa-miR-548k	CLIP-seq
MIRT1410334	hsa-miR-548n	CLIP-seq
MIRT1410335	hsa-miR-562	CLIP-seq
MIRT1410336	hsa-miR-577	CLIP-seq
MIRT1410337	hsa-miR-587	CLIP-seq
MIRT1410338	hsa-miR-600	CLIP-seq
MIRT1410339	hsa-miR-634	CLIP-seq
MIRT1410340	hsa-miR-93	CLIP-seq
MIRT1410252	hsa-miR-101	CLIP-seq
MIRT1410256	hsa-miR-1244	CLIP-seq
MIRT1410257	hsa-miR-1255a	CLIP-seq
MIRT1410258	hsa-miR-1255b	CLIP-seq
MIRT1410259	hsa-miR-127-5p	CLIP-seq
MIRT1410262	hsa-miR-130a	CLIP-seq
MIRT1410263	hsa-miR-130b	CLIP-seq
MIRT1410264	hsa-miR-134	CLIP-seq
MIRT1410266	hsa-miR-144	CLIP-seq
MIRT1410267	hsa-miR-148a	CLIP-seq
MIRT1410268	hsa-miR-148b	CLIP-seq
MIRT1410269	hsa-miR-152	CLIP-seq
MIRT1410271	hsa-miR-199a-3p	CLIP-seq
MIRT1410272	hsa-miR-199b-3p	CLIP-seq
MIRT1410275	hsa-miR-298	CLIP-seq
MIRT1410279	hsa-miR-301a	CLIP-seq
MIRT1410280	hsa-miR-301b	CLIP-seq
MIRT1410287	hsa-miR-3118	CLIP-seq
MIRT1410288	hsa-miR-3129-5p	CLIP-seq
MIRT1410290	hsa-miR-3148	CLIP-seq
MIRT1410293	hsa-miR-3170	CLIP-seq
MIRT2122957	hsa-miR-3202	CLIP-seq
MIRT1410296	hsa-miR-338-3p	CLIP-seq
MIRT2122958	hsa-miR-3614-5p	CLIP-seq
MIRT1410300	hsa-miR-3666	CLIP-seq
MIRT1410301	hsa-miR-3688-3p	CLIP-seq
MIRT1410304	hsa-miR-3919	CLIP-seq
MIRT1410305	hsa-miR-3925-5p	CLIP-seq
MIRT1410307	hsa-miR-4276	CLIP-seq
MIRT1410308	hsa-miR-4295	CLIP-seq
MIRT2122959	hsa-miR-4445	CLIP-seq
MIRT2122960	hsa-miR-4453	CLIP-seq
MIRT2122961	hsa-miR-4533	CLIP-seq
MIRT2122962	hsa-miR-4538	CLIP-seq
MIRT1410311	hsa-miR-454	CLIP-seq
MIRT2122963	hsa-miR-4680-3p	CLIP-seq
MIRT1410313	hsa-miR-4703-3p	CLIP-seq
MIRT2122964	hsa-miR-4764-5p	CLIP-seq
MIRT1410320	hsa-miR-4797-5p	CLIP-seq
MIRT1410322	hsa-miR-490-5p	CLIP-seq
MIRT2122965	hsa-miR-499-3p	CLIP-seq
MIRT2122966	hsa-miR-499a-3p	CLIP-seq
MIRT1410333	hsa-miR-548k	CLIP-seq
MIRT1410334	hsa-miR-548n	CLIP-seq
MIRT1410337	hsa-miR-587	CLIP-seq
MIRT1410338	hsa-miR-600	CLIP-seq
MIRT1410339	hsa-miR-634	CLIP-seq
MIRT2122967	hsa-miR-665	CLIP-seq
MIRT2122968	hsa-miR-890	CLIP-seq
MIRT1410253	hsa-miR-106a	CLIP-seq
MIRT1410254	hsa-miR-106b	CLIP-seq
MIRT1410255	hsa-miR-1206	CLIP-seq
MIRT1410256	hsa-miR-1244	CLIP-seq
MIRT1410257	hsa-miR-1255a	CLIP-seq
MIRT1410258	hsa-miR-1255b	CLIP-seq
MIRT1410259	hsa-miR-127-5p	CLIP-seq
MIRT1410262	hsa-miR-130a	CLIP-seq
MIRT1410263	hsa-miR-130b	CLIP-seq
MIRT2345275	hsa-miR-1323	CLIP-seq
MIRT1410264	hsa-miR-134	CLIP-seq
MIRT1410265	hsa-miR-142-5p	CLIP-seq
MIRT1410267	hsa-miR-148a	CLIP-seq
MIRT1410268	hsa-miR-148b	CLIP-seq
MIRT1410269	hsa-miR-152	CLIP-seq
MIRT1410270	hsa-miR-17	CLIP-seq
MIRT1410273	hsa-miR-20a	CLIP-seq
MIRT1410274	hsa-miR-20b	CLIP-seq
MIRT2345276	hsa-miR-23a	CLIP-seq
MIRT2345277	hsa-miR-23b	CLIP-seq
MIRT2345278	hsa-miR-23c	CLIP-seq
MIRT1410279	hsa-miR-301a	CLIP-seq
MIRT1410280	hsa-miR-301b	CLIP-seq
MIRT1410281	hsa-miR-302a	CLIP-seq
MIRT1410282	hsa-miR-302b	CLIP-seq
MIRT1410283	hsa-miR-302c	CLIP-seq
MIRT1410284	hsa-miR-302d	CLIP-seq
MIRT1410285	hsa-miR-302e	CLIP-seq
MIRT1410286	hsa-miR-3074-3p	CLIP-seq
MIRT1410287	hsa-miR-3118	CLIP-seq
MIRT1410289	hsa-miR-3143	CLIP-seq
MIRT1410292	hsa-miR-3163	CLIP-seq
MIRT1410293	hsa-miR-3170	CLIP-seq
MIRT1410294	hsa-miR-323b-3p	CLIP-seq
MIRT1410295	hsa-miR-329	CLIP-seq
MIRT1410296	hsa-miR-338-3p	CLIP-seq
MIRT1410298	hsa-miR-362-3p	CLIP-seq
MIRT1410300	hsa-miR-3666	CLIP-seq
MIRT1410301	hsa-miR-3688-3p	CLIP-seq
MIRT2345279	hsa-miR-3692	CLIP-seq
MIRT2345280	hsa-miR-369-3p	CLIP-seq
MIRT1410302	hsa-miR-372	CLIP-seq
MIRT1410303	hsa-miR-373	CLIP-seq
MIRT2345281	hsa-miR-378g	CLIP-seq
MIRT1410304	hsa-miR-3919	CLIP-seq
MIRT1410305	hsa-miR-3925-5p	CLIP-seq
MIRT2345282	hsa-miR-3978	CLIP-seq
MIRT1410307	hsa-miR-4276	CLIP-seq
MIRT1410308	hsa-miR-4295	CLIP-seq
MIRT2345283	hsa-miR-4427	CLIP-seq
MIRT1410310	hsa-miR-452	CLIP-seq
MIRT1410311	hsa-miR-454	CLIP-seq
MIRT1410312	hsa-miR-4676-3p	CLIP-seq
MIRT2122963	hsa-miR-4680-3p	CLIP-seq
MIRT1410314	hsa-miR-4719	CLIP-seq
MIRT2345284	hsa-miR-4733-5p	CLIP-seq
MIRT2345285	hsa-miR-4775	CLIP-seq
MIRT1410320	hsa-miR-4797-5p	CLIP-seq
MIRT1410322	hsa-miR-490-5p	CLIP-seq
MIRT1410326	hsa-miR-519d	CLIP-seq
MIRT1410327	hsa-miR-520a-3p	CLIP-seq
MIRT1410328	hsa-miR-520b	CLIP-seq
MIRT1410329	hsa-miR-520c-3p	CLIP-seq
MIRT1410330	hsa-miR-520d-3p	CLIP-seq
MIRT2345286	hsa-miR-520d-5p	CLIP-seq
MIRT1410331	hsa-miR-520e	CLIP-seq
MIRT2345287	hsa-miR-524-5p	CLIP-seq
MIRT2345288	hsa-miR-548a-3p	CLIP-seq
MIRT2345289	hsa-miR-548e	CLIP-seq
MIRT2345290	hsa-miR-548f	CLIP-seq
MIRT1410333	hsa-miR-548k	CLIP-seq
MIRT2345291	hsa-miR-548o	CLIP-seq
MIRT1410337	hsa-miR-587	CLIP-seq
MIRT2345292	hsa-miR-590-3p	CLIP-seq
MIRT1410338	hsa-miR-600	CLIP-seq
MIRT1410339	hsa-miR-634	CLIP-seq
MIRT1410340	hsa-miR-93	CLIP-seq
MIRT1410257	hsa-miR-1255a	CLIP-seq
MIRT1410258	hsa-miR-1255b	CLIP-seq
MIRT1410259	hsa-miR-127-5p	CLIP-seq
MIRT1410304	hsa-miR-3919	CLIP-seq
MIRT1410305	hsa-miR-3925-5p	CLIP-seq
MIRT1410320	hsa-miR-4797-5p	CLIP-seq
MIRT1410322	hsa-miR-490-5p	CLIP-seq
MIRT2345292	hsa-miR-590-3p	CLIP-seq
MIRT1410338	hsa-miR-600	CLIP-seq
MIRT1410256	hsa-miR-1244	CLIP-seq
MIRT2345275	hsa-miR-1323	CLIP-seq
MIRT2433776	hsa-miR-3120-3p	CLIP-seq
MIRT2433777	hsa-miR-545	CLIP-seq
MIRT2345291	hsa-miR-548o	CLIP-seq
MIRT2433778	hsa-miR-548p	CLIP-seq
MIRT2440891	hsa-miR-3182	CLIP-seq
MIRT2440892	hsa-miR-4693-3p	CLIP-seq
MIRT2461121	hsa-miR-2355-3p	CLIP-seq
MIRT2461122	hsa-miR-28-5p	CLIP-seq
MIRT2461123	hsa-miR-3125	CLIP-seq
MIRT2461124	hsa-miR-3139	CLIP-seq
MIRT2461125	hsa-miR-3916	CLIP-seq
MIRT2122960	hsa-miR-4453	CLIP-seq
MIRT2122962	hsa-miR-4538	CLIP-seq
MIRT2461126	hsa-miR-676	CLIP-seq
MIRT2461127	hsa-miR-708	CLIP-seq
MIRT2461128	hsa-miR-877	CLIP-seq
MIRT2638349	hsa-miR-1237	CLIP-seq
MIRT2638350	hsa-miR-1248	CLIP-seq
MIRT2638351	hsa-miR-186	CLIP-seq
MIRT2638352	hsa-miR-2276	CLIP-seq
MIRT2638353	hsa-miR-27a	CLIP-seq
MIRT2638354	hsa-miR-27b	CLIP-seq
MIRT2638355	hsa-miR-3133	CLIP-seq
MIRT2440891	hsa-miR-3182	CLIP-seq
MIRT2638356	hsa-miR-337-3p	CLIP-seq
MIRT2638357	hsa-miR-3913-3p	CLIP-seq
MIRT2638358	hsa-miR-410	CLIP-seq
MIRT2638359	hsa-miR-4257	CLIP-seq
MIRT2638360	hsa-miR-4279	CLIP-seq
MIRT2440892	hsa-miR-4693-3p	CLIP-seq
MIRT1410314	hsa-miR-4719	CLIP-seq
MIRT2638361	hsa-miR-4772-3p	CLIP-seq
MIRT2638362	hsa-miR-489	CLIP-seq
MIRT2638363	hsa-miR-513a-5p	CLIP-seq
MIRT1410325	hsa-miR-513b	CLIP-seq
MIRT2638364	hsa-miR-543	CLIP-seq
MIRT2638365	hsa-miR-544	CLIP-seq
MIRT2638366	hsa-miR-548aa	CLIP-seq
MIRT2345292	hsa-miR-590-3p	CLIP-seq
MIRT2638367	hsa-miR-873	CLIP-seq
MIRT1410253	hsa-miR-106a	CLIP-seq
MIRT1410254	hsa-miR-106b	CLIP-seq
MIRT1410255	hsa-miR-1206	CLIP-seq
MIRT2692623	hsa-miR-1269	CLIP-seq
MIRT2692624	hsa-miR-1269b	CLIP-seq
MIRT1410265	hsa-miR-142-5p	CLIP-seq
MIRT1410270	hsa-miR-17	CLIP-seq
MIRT1410273	hsa-miR-20a	CLIP-seq
MIRT1410274	hsa-miR-20b	CLIP-seq
MIRT1410276	hsa-miR-29a	CLIP-seq
MIRT1410277	hsa-miR-29b	CLIP-seq
MIRT1410278	hsa-miR-29c	CLIP-seq
MIRT1410281	hsa-miR-302a	CLIP-seq
MIRT1410282	hsa-miR-302b	CLIP-seq
MIRT1410283	hsa-miR-302c	CLIP-seq
MIRT1410284	hsa-miR-302d	CLIP-seq
MIRT1410285	hsa-miR-302e	CLIP-seq
MIRT1410289	hsa-miR-3143	CLIP-seq
MIRT1410297	hsa-miR-3609	CLIP-seq
MIRT1410299	hsa-miR-3646	CLIP-seq
MIRT2345280	hsa-miR-369-3p	CLIP-seq
MIRT1410302	hsa-miR-372	CLIP-seq
MIRT1410303	hsa-miR-373	CLIP-seq
MIRT2692625	hsa-miR-374c	CLIP-seq
MIRT2122960	hsa-miR-4453	CLIP-seq
MIRT1410310	hsa-miR-452	CLIP-seq
MIRT2692626	hsa-miR-4529-3p	CLIP-seq
MIRT2122962	hsa-miR-4538	CLIP-seq
MIRT1410312	hsa-miR-4676-3p	CLIP-seq
MIRT1410317	hsa-miR-4774-5p	CLIP-seq
MIRT1410319	hsa-miR-4796-3p	CLIP-seq
MIRT2122965	hsa-miR-499-3p	CLIP-seq
MIRT2122966	hsa-miR-499a-3p	CLIP-seq
MIRT1410324	hsa-miR-512-3p	CLIP-seq
MIRT1410326	hsa-miR-519d	CLIP-seq
MIRT1410327	hsa-miR-520a-3p	CLIP-seq
MIRT1410328	hsa-miR-520b	CLIP-seq
MIRT1410329	hsa-miR-520c-3p	CLIP-seq
MIRT1410330	hsa-miR-520d-3p	CLIP-seq
MIRT1410331	hsa-miR-520e	CLIP-seq
MIRT1410332	hsa-miR-548ah	CLIP-seq
MIRT1410335	hsa-miR-562	CLIP-seq
MIRT1410336	hsa-miR-577	CLIP-seq
MIRT2692627	hsa-miR-655	CLIP-seq
MIRT1410340	hsa-miR-93	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	30126976
GO:0007520	Process	Myoblast fusion	IEA
GO:0008542	Process	Visual learning	IEA
GO:0014069	Component	Postsynaptic density	IEA
GO:0030425	Component	Dendrite	IEA
GO:0043025	Component	Neuronal cell body	IEA
GO:0043679	Component	Axon terminus	IEA
GO:0097062	Process	Dendritic spine maintenance	IEA

MIM	HGNC	e!Ensembl
611397	29364	ENSG00000115183

Protein

UniProt ID

Q9C0D5

Protein name

Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)

Protein function

May be a scaffold component in the postsynaptic density.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12796	Ank_2	938 → 1030	Ankyrin repeats (3 copies)	Repeat
PF12796	Ank_2	1044 → 1142	Ankyrin repeats (3 copies)	Repeat
PF12796	Ank_2	1170 → 1241	Ankyrin repeats (3 copies)	Repeat

Sequence

MLKAVLKKSREGGKGGKKEAGSDFGPETSPVLHLDHSADSPVSSLPTAEDTYRVSLAKGV
SMSLPSSPLLPRQSHLVQSRVNKKSPGPVRKPKYVESPRVPGDAVIMPFREVAKPTEPDE
HEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNETMCTALSQGISPCSTLT
SSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRS
GSSLEWNKDGNLRLGVQKGVLHDRRADNCSPVAEEETTGSAESTLPKAESSAGDGPVPYS
QGSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAQEVKARFA
PYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELAENRGAVVVGNVGFGK
TAIISKLVALSCHGSRMRQIASNSPGSSPKTSDPTQDLHFTPLLSPSSSTSASSTAKTPL
GSISAENQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRD
LLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFH
KPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDL
HAYVQHRVHSSQDILSNISLNGKADATLIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLV
IKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAG
HIQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGH
ALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSA
ALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGAC
LDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYL
LTCEWSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGE
TALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNL
SDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEE
GAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVV
VALLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFP
REGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAK
RNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLPAPLNDSE
NEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQPSSSVPSSYIRNLQEGLQSKGR
PVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLGSGQSAVRNGSMKVQISSQN
PPPSPMPGRIAATPAGSRTQHLEGTGTFTTRAGCGHFGDRLGPSQNVRLQCGENGPAHPL
PSKTKTTERLLSHSSVAVDAAPPNQGGLATCSDVRHPASLTSSGSSGSPSSSIKMSSSTS
SLTSSSSFSDGFKVQGPDTRIKDKVVTHVQSGTAEHRPRNTPFMGIMDKTARFQQQSNPP
SRSWHCPAPEGLLTNTSSAAGLQSANTEKPSLMQVGGYNNQAKTCSVSTLSASVHNGAQV
KELEESKCQIPVHSQENRITKTVSHLYQESISKQQPHISNEAHRSHLTAAKPKRSFIESN
V

Sequence length

1861

Interactions

View interactions

Show/Hide Causal Diseases (5)

Disease term	Disease name	dbSNP ID	References
Causal
Cholelithiasis	Cholelithiasis	rs121918440, rs72552778, rs387906528, rs759202962, rs377160065, rs1051861187, rs757693457, rs752563752	17632509
Colonic neoplasms	Malignant tumor of colon	rs267607789, rs774277300, rs781222233, rs1060502734, rs1060503333, rs1339238483	30510241
Colorectal cancer	Colorectal Carcinoma, Adenocarcinoma of large intestine	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)	30510241
Colorectal neoplasms	Colorectal Neoplasms, Malignant neoplasm of large intestine	rs28929483, rs63751108, rs28929484, rs63749831, rs63750047, rs63751207, rs63749811, rs1553350126, rs63750875, rs63750955, rs587776706, rs63750871, rs587776715, rs63751466, rs63750049 View all (1682 more)	30510241
Prostate cancer	Prostate carcinoma	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	24974847

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.		GWAS, CBGDA

TANC1 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1)