DISP2 (dispatched RND transporter family member 2)

Gene

• Entrez ID: 85455
• Gene name: Dispatched RND transporter family member 2
• Gene symbol: DISP2
• Synonyms (NCBI Gene): C15orf36, DISPB, HsT16908, LINC00594
• Chromosome: 15
• Chromosome location: 15q15.1
• Summary: This gene is one of two human homologs of a segment-polarity gene known as dispatched identified in Drosophila. The product of this gene may be required for normal Hedgehog (Hh) signaling during embryonic pattern formation. [provided by RefSeq, Jan 2017]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020018	hsa-miR-375	Microarray	20215506
MIRT937311	hsa-miR-1265	CLIP-seq
MIRT937312	hsa-miR-1270	CLIP-seq
MIRT937313	hsa-miR-1287	CLIP-seq
MIRT937314	hsa-miR-1290	CLIP-seq
MIRT937315	hsa-miR-135a	CLIP-seq
MIRT937316	hsa-miR-135b	CLIP-seq
MIRT937317	hsa-miR-146b-3p	CLIP-seq
MIRT937318	hsa-miR-198	CLIP-seq
MIRT937319	hsa-miR-2355-5p	CLIP-seq
MIRT937320	hsa-miR-2392	CLIP-seq
MIRT937321	hsa-miR-3126-3p	CLIP-seq
MIRT937322	hsa-miR-3167	CLIP-seq
MIRT937323	hsa-miR-3176	CLIP-seq
MIRT937324	hsa-miR-339-5p	CLIP-seq
MIRT937325	hsa-miR-3652	CLIP-seq
MIRT937326	hsa-miR-3922-3p	CLIP-seq
MIRT937327	hsa-miR-4286	CLIP-seq
MIRT937328	hsa-miR-4297	CLIP-seq
MIRT937329	hsa-miR-4430	CLIP-seq
MIRT937330	hsa-miR-4434	CLIP-seq
MIRT937331	hsa-miR-4488	CLIP-seq
MIRT937332	hsa-miR-4505	CLIP-seq
MIRT937333	hsa-miR-450b-3p	CLIP-seq
MIRT937334	hsa-miR-4516	CLIP-seq
MIRT937335	hsa-miR-4531	CLIP-seq
MIRT937336	hsa-miR-4643	CLIP-seq
MIRT937337	hsa-miR-466	CLIP-seq
MIRT937338	hsa-miR-4697-5p	CLIP-seq
MIRT937339	hsa-miR-4707-5p	CLIP-seq
MIRT937340	hsa-miR-4732-3p	CLIP-seq
MIRT937341	hsa-miR-4789-3p	CLIP-seq
MIRT937342	hsa-miR-578	CLIP-seq
MIRT937343	hsa-miR-620	CLIP-seq
MIRT937344	hsa-miR-643	CLIP-seq
MIRT937345	hsa-miR-769-3p	CLIP-seq
MIRT937346	hsa-miR-876-5p	CLIP-seq
MIRT937347	hsa-miR-937	CLIP-seq
MIRT937324	hsa-miR-339-5p	CLIP-seq
MIRT1977462	hsa-miR-3663-5p	CLIP-seq
MIRT1977463	hsa-miR-3691-5p	CLIP-seq
MIRT1977464	hsa-miR-4268	CLIP-seq
MIRT1977465	hsa-miR-4287	CLIP-seq
MIRT1977466	hsa-miR-4469	CLIP-seq
MIRT1977467	hsa-miR-4685-3p	CLIP-seq
MIRT1977468	hsa-miR-4752	CLIP-seq
MIRT1977469	hsa-miR-4786-5p	CLIP-seq
MIRT1977470	hsa-miR-769-5p	CLIP-seq
MIRT2212778	hsa-miR-1237	CLIP-seq
MIRT2212779	hsa-miR-1248	CLIP-seq
MIRT2212780	hsa-miR-1976	CLIP-seq
MIRT2212781	hsa-miR-370	CLIP-seq
MIRT2212782	hsa-miR-4279	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007224	Process	Smoothened signaling pathway	IBA
GO:0007224	Process	Smoothened signaling pathway	NAS	16258256
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: 607503
• HGNC: 19712
• e!Ensembl: ENSG00000140323

Protein

• UniProt ID: A7MBM2
• Protein name: Protein dispatched homolog 2
• Sequence:

  MDGDSSSSSGGSGPAPGPGPEGEQRPEGEPLAPDGGSPDSTQTKAVPPEASPERSCSLHS
  CPLEDPSSSSGPPPTTSTLQPVGPSSPLAPAHFTYPRALQEYQGGSSLPGLGDRAALCSH
  GSSLSPSPAPSQRDGTWKPPAVQHHVVSVRQERAFQMPKSYSQLIAEWPVAVLMLCLAVI
  FLCTLAGLLGARLPDFSKPLLGFEPRDTDIGSKLVVWRALQALTGPRKLLFLSPDLELNS
  SSSHNTLRPAPRGSAQESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLW
  NLHAIHSMCRMEQDQIRSHTSFGALCQRTAANQCCPSWSLGNYLAVLSNRSSCLDTTQAD
  AARTLALLRTCALYYHSGALVPSCLGPGQNKSPRCAQVPTKCSQSSAIYQLLHFLLDRDF
  LSPQTTDYQVPSLKYSLLFLPTPKGASLMDIYLDRLATPWGLADNYTSVTGMDLGLKQEL
  LRHFLVQDTVYPLLALVAIFFGMALYLRSLFLTLMVLLGVLGSLLVAFFLYQVAFRMAYF
  PFVNLAALLLLSSVCANHTLIFFDLWRLSKSQLPSGGLAQRVGRTMHHFGYLLLVSGLTT
  SAAFYASYLSRLPAVRCLALFMGTAVLVHLALTLVWLPASAVLHERYLARGCARRARGRW
  EGSAPRRLLLALHRRLRGLRRAAAGTSRLLFQRLLPCGVIKFRYIWICWFAALAAGGAYI
  AGVSPRLRLPTLPPPGGQVFRPSHPFERFDAEYRQLFLFEQLPQGEGGHMPVVLVWGVLP
  VDTGDPLDPRSNSSLVRDPAFSASGPEAQRWLLALCHRARNQSFFDTLQEGWPTLCFVET
  LQRWMESPSCARLGPDLCCGHSDFPWAPQFFLHCLKMMALEQGPDGTQDLGLRFDAHGSL
  AALVLQFQTNFRNSPDYNQTQLFYNEVSHWLAAELGMAPPGLRRGWFTSRLELYSLQHSL
  STEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLEWQLNTAEAL
  FLSASVGLSVDFTVNYCISYHLCPHPDRLSRVAFSLRQTSCATAVGAAALFAAGVLMLPA
  TVLLYRKLGIILMMVKCVSCGFASFFFQSLCCFFGPEKNCGQILWPCAHLPWDAGTGDPG
  GEKAGRPRPGSVGGMPGSCSEQYELQPLARRRSPSFDTSTATSKLSHRPSVLSEDLQLHD
  GPCCSRPPPAPASPRELLLDHQAVFSQCPALQTSSPYKQAGPSPKTRARQDSQGEEAEPL
  PASPEAPAHSPKAKAADPPDGFCSSASTLEGLSVSDETCLSTSEPSARVPDSVGVSPDDL
  DDTGQPVLERGQLNGKRDTLWLALRETVYDPSLPASHHSSLSWKGRGGPGDGSPVVLPNS
  QPDLPDVWLRRPSTHTSGYSS

• Sequence length: 1401

Pathways

Reactome:

Release of Hh-Np from the secreting cell