Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	85443
Gene name Gene Name - the full gene name approved by the HGNC.	Doublecortin like kinase 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	DCLK3
Synonyms (NCBI Gene) Gene synonyms aliases	CLR, DCAMKL3, DCDC3C, DCK3
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3p22.2

Show/Hide all(158)

miRTarBase ID	miRNA	Experiments	Reference
MIRT721220	hsa-miR-548at-5p	HITS-CLIP	19536157
MIRT721219	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT721218	hsa-miR-6793-3p	HITS-CLIP	19536157
MIRT721217	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT721216	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT721215	hsa-miR-877-3p	HITS-CLIP	19536157
MIRT721214	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT721213	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT721212	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT643789	hsa-miR-362-5p	HITS-CLIP	23824327
MIRT643788	hsa-miR-500b-5p	HITS-CLIP	23824327
MIRT643787	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT643786	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT643785	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT643784	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT643783	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT643782	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT643781	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT643780	hsa-miR-3191-5p	HITS-CLIP	23824327
MIRT643779	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT643778	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT643777	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT721220	hsa-miR-548at-5p	HITS-CLIP	19536157
MIRT721219	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT721218	hsa-miR-6793-3p	HITS-CLIP	19536157
MIRT721217	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT721216	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT721215	hsa-miR-877-3p	HITS-CLIP	19536157
MIRT721214	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT721213	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT721212	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT643789	hsa-miR-362-5p	HITS-CLIP	23824327
MIRT643788	hsa-miR-500b-5p	HITS-CLIP	23824327
MIRT643787	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT643786	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT643785	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT643784	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT643783	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT643782	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT643781	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT643780	hsa-miR-3191-5p	HITS-CLIP	23824327
MIRT643779	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT643778	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT643777	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT926189	hsa-miR-1226	CLIP-seq
MIRT926190	hsa-miR-129-5p	CLIP-seq
MIRT926191	hsa-miR-2113	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT926193	hsa-miR-4289	CLIP-seq
MIRT926194	hsa-miR-4474-3p	CLIP-seq
MIRT926195	hsa-miR-451b	CLIP-seq
MIRT926196	hsa-miR-4640-3p	CLIP-seq
MIRT926197	hsa-miR-4687-3p	CLIP-seq
MIRT926198	hsa-miR-4733-3p	CLIP-seq
MIRT926199	hsa-miR-556-3p	CLIP-seq
MIRT926200	hsa-miR-605	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT926202	hsa-miR-634	CLIP-seq
MIRT926203	hsa-miR-664	CLIP-seq
MIRT926204	hsa-miR-885-5p	CLIP-seq
MIRT926189	hsa-miR-1226	CLIP-seq
MIRT926191	hsa-miR-2113	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT926198	hsa-miR-4733-3p	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT926202	hsa-miR-634	CLIP-seq
MIRT926189	hsa-miR-1226	CLIP-seq
MIRT926191	hsa-miR-2113	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT926198	hsa-miR-4733-3p	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT926202	hsa-miR-634	CLIP-seq
MIRT926189	hsa-miR-1226	CLIP-seq
MIRT926191	hsa-miR-2113	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT926198	hsa-miR-4733-3p	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT926202	hsa-miR-634	CLIP-seq
MIRT1974385	hsa-let-7a	CLIP-seq
MIRT1974386	hsa-let-7b	CLIP-seq
MIRT1974387	hsa-let-7c	CLIP-seq
MIRT1974388	hsa-let-7d	CLIP-seq
MIRT1974389	hsa-let-7e	CLIP-seq
MIRT1974390	hsa-let-7f	CLIP-seq
MIRT1974391	hsa-let-7g	CLIP-seq
MIRT1974392	hsa-let-7i	CLIP-seq
MIRT1974393	hsa-miR-1285	CLIP-seq
MIRT1974394	hsa-miR-202	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT1974395	hsa-miR-3065-3p	CLIP-seq
MIRT1974396	hsa-miR-3187-5p	CLIP-seq
MIRT1974397	hsa-miR-370	CLIP-seq
MIRT1974398	hsa-miR-4458	CLIP-seq
MIRT1974399	hsa-miR-4461	CLIP-seq
MIRT1974400	hsa-miR-4500	CLIP-seq
MIRT1974401	hsa-miR-4731-5p	CLIP-seq
MIRT1974402	hsa-miR-4763-5p	CLIP-seq
MIRT1974403	hsa-miR-4775	CLIP-seq
MIRT1974404	hsa-miR-514	CLIP-seq
MIRT1974405	hsa-miR-514b-3p	CLIP-seq
MIRT1974406	hsa-miR-612	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT1974407	hsa-miR-98	CLIP-seq
MIRT1974385	hsa-let-7a	CLIP-seq
MIRT1974386	hsa-let-7b	CLIP-seq
MIRT1974387	hsa-let-7c	CLIP-seq
MIRT1974388	hsa-let-7d	CLIP-seq
MIRT1974389	hsa-let-7e	CLIP-seq
MIRT1974390	hsa-let-7f	CLIP-seq
MIRT1974391	hsa-let-7g	CLIP-seq
MIRT1974392	hsa-let-7i	CLIP-seq
MIRT1974394	hsa-miR-202	CLIP-seq
MIRT2209860	hsa-miR-203	CLIP-seq
MIRT2209861	hsa-miR-3652	CLIP-seq
MIRT2209862	hsa-miR-4430	CLIP-seq
MIRT2209863	hsa-miR-4432	CLIP-seq
MIRT1974398	hsa-miR-4458	CLIP-seq
MIRT1974399	hsa-miR-4461	CLIP-seq
MIRT2209864	hsa-miR-4488	CLIP-seq
MIRT2209865	hsa-miR-4492	CLIP-seq
MIRT2209866	hsa-miR-4498	CLIP-seq
MIRT2209867	hsa-miR-4499	CLIP-seq
MIRT1974400	hsa-miR-4500	CLIP-seq
MIRT2209868	hsa-miR-4638-3p	CLIP-seq
MIRT2209869	hsa-miR-4697-5p	CLIP-seq
MIRT2209870	hsa-miR-499-5p	CLIP-seq
MIRT1974404	hsa-miR-514	CLIP-seq
MIRT1974405	hsa-miR-514b-3p	CLIP-seq
MIRT2209871	hsa-miR-548g	CLIP-seq
MIRT2209872	hsa-miR-637	CLIP-seq
MIRT2209873	hsa-miR-642b	CLIP-seq
MIRT2209874	hsa-miR-762	CLIP-seq
MIRT1974407	hsa-miR-98	CLIP-seq
MIRT1974385	hsa-let-7a	CLIP-seq
MIRT1974386	hsa-let-7b	CLIP-seq
MIRT1974387	hsa-let-7c	CLIP-seq
MIRT1974388	hsa-let-7d	CLIP-seq
MIRT1974389	hsa-let-7e	CLIP-seq
MIRT1974390	hsa-let-7f	CLIP-seq
MIRT1974391	hsa-let-7g	CLIP-seq
MIRT1974392	hsa-let-7i	CLIP-seq
MIRT2386776	hsa-miR-1236	CLIP-seq
MIRT2386777	hsa-miR-145	CLIP-seq
MIRT2386778	hsa-miR-1825	CLIP-seq
MIRT2386779	hsa-miR-190	CLIP-seq
MIRT2386780	hsa-miR-190b	CLIP-seq
MIRT2386781	hsa-miR-199a-5p	CLIP-seq
MIRT2386782	hsa-miR-199b-5p	CLIP-seq
MIRT1974394	hsa-miR-202	CLIP-seq
MIRT1974398	hsa-miR-4458	CLIP-seq
MIRT1974399	hsa-miR-4461	CLIP-seq
MIRT1974400	hsa-miR-4500	CLIP-seq
MIRT1974404	hsa-miR-514	CLIP-seq
MIRT1974405	hsa-miR-514b-3p	CLIP-seq
MIRT2386783	hsa-miR-593	CLIP-seq
MIRT2209873	hsa-miR-642b	CLIP-seq
MIRT2386784	hsa-miR-654-3p	CLIP-seq
MIRT1974407	hsa-miR-98	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004672	Function	Protein kinase activity	IBA	21873635
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0018105	Process	Peptidyl-serine phosphorylation	IBA	21873635
GO:0106310	Function	Protein serine kinase activity	IEA
GO:0106311	Function	Protein threonine kinase activity	IEA

MIM	HGNC	e!Ensembl
613167	19005	ENSG00000163673

Protein

UniProt ID

Q9C098

Protein name

Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	356 → 613	Protein kinase domain	Domain

Sequence

MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
VILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKK
RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS

Sequence length

648

Interactions

View interactions

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID
Causal
Colorectal cancer	Adenocarcinoma of large intestine	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800 View all (467 more)
Lung carcinoma	Squamous cell carcinoma of lung, Large cell carcinoma of lung	rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355 View all (44 more)
Renal carcinoma	Conventional (Clear Cell) Renal Cell Carcinoma	rs121913668, rs121913670, rs121913243, rs786202724

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining
Bipolar Disorder	Associate	40562893
Colorectal Neoplasms	Associate	28195176
Dendritic Cell Sarcoma Follicular	Associate	37991344
Infections	Associate	29272097
Inflammation	Associate	34315926
Melanoma	Associate	36353633, 37991344
Neoplasms	Associate	28195176, 36353633, 37991344
Urinary Bladder Neoplasms	Associate	36131933

DCLK3 (doublecortin like kinase 3)