Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	85443
Gene name	Doublecortin like kinase 3
Gene symbol	DCLK3
Synonyms (NCBI Gene)	CLRDCAMKL3DCDC3CDCK3
Chromosome	3
Chromosome location	3p22.2

158

Show/Hide all (158)

miRTarBase ID	miRNA	Experiments	Reference
MIRT721220	hsa-miR-548at-5p	HITS-CLIP	19536157
MIRT721219	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT721218	hsa-miR-6793-3p	HITS-CLIP	19536157
MIRT721217	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT721216	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT721215	hsa-miR-877-3p	HITS-CLIP	19536157
MIRT721214	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT721213	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT721212	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT643789	hsa-miR-362-5p	HITS-CLIP	23824327
MIRT643788	hsa-miR-500b-5p	HITS-CLIP	23824327
MIRT643787	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT643786	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT643785	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT643784	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT643783	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT643782	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT643781	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT643780	hsa-miR-3191-5p	HITS-CLIP	23824327
MIRT643779	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT643778	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT643777	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT721220	hsa-miR-548at-5p	HITS-CLIP	19536157
MIRT721219	hsa-miR-186-3p	HITS-CLIP	19536157
MIRT721218	hsa-miR-6793-3p	HITS-CLIP	19536157
MIRT721217	hsa-miR-6892-3p	HITS-CLIP	19536157
MIRT721216	hsa-miR-2276-5p	HITS-CLIP	19536157
MIRT721215	hsa-miR-877-3p	HITS-CLIP	19536157
MIRT721214	hsa-miR-1236-3p	HITS-CLIP	19536157
MIRT721213	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT721212	hsa-miR-642a-5p	HITS-CLIP	19536157
MIRT643789	hsa-miR-362-5p	HITS-CLIP	23824327
MIRT643788	hsa-miR-500b-5p	HITS-CLIP	23824327
MIRT643787	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT643786	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT643785	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT643784	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT643783	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT643782	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT643781	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT643780	hsa-miR-3191-5p	HITS-CLIP	23824327
MIRT643779	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT643778	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT643777	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT926189	hsa-miR-1226	CLIP-seq
MIRT926190	hsa-miR-129-5p	CLIP-seq
MIRT926191	hsa-miR-2113	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT926193	hsa-miR-4289	CLIP-seq
MIRT926194	hsa-miR-4474-3p	CLIP-seq
MIRT926195	hsa-miR-451b	CLIP-seq
MIRT926196	hsa-miR-4640-3p	CLIP-seq
MIRT926197	hsa-miR-4687-3p	CLIP-seq
MIRT926198	hsa-miR-4733-3p	CLIP-seq
MIRT926199	hsa-miR-556-3p	CLIP-seq
MIRT926200	hsa-miR-605	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT926202	hsa-miR-634	CLIP-seq
MIRT926203	hsa-miR-664	CLIP-seq
MIRT926204	hsa-miR-885-5p	CLIP-seq
MIRT926189	hsa-miR-1226	CLIP-seq
MIRT926191	hsa-miR-2113	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT926198	hsa-miR-4733-3p	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT926202	hsa-miR-634	CLIP-seq
MIRT926189	hsa-miR-1226	CLIP-seq
MIRT926191	hsa-miR-2113	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT926198	hsa-miR-4733-3p	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT926202	hsa-miR-634	CLIP-seq
MIRT926189	hsa-miR-1226	CLIP-seq
MIRT926191	hsa-miR-2113	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT926198	hsa-miR-4733-3p	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT926202	hsa-miR-634	CLIP-seq
MIRT1974385	hsa-let-7a	CLIP-seq
MIRT1974386	hsa-let-7b	CLIP-seq
MIRT1974387	hsa-let-7c	CLIP-seq
MIRT1974388	hsa-let-7d	CLIP-seq
MIRT1974389	hsa-let-7e	CLIP-seq
MIRT1974390	hsa-let-7f	CLIP-seq
MIRT1974391	hsa-let-7g	CLIP-seq
MIRT1974392	hsa-let-7i	CLIP-seq
MIRT1974393	hsa-miR-1285	CLIP-seq
MIRT1974394	hsa-miR-202	CLIP-seq
MIRT926192	hsa-miR-218	CLIP-seq
MIRT1974395	hsa-miR-3065-3p	CLIP-seq
MIRT1974396	hsa-miR-3187-5p	CLIP-seq
MIRT1974397	hsa-miR-370	CLIP-seq
MIRT1974398	hsa-miR-4458	CLIP-seq
MIRT1974399	hsa-miR-4461	CLIP-seq
MIRT1974400	hsa-miR-4500	CLIP-seq
MIRT1974401	hsa-miR-4731-5p	CLIP-seq
MIRT1974402	hsa-miR-4763-5p	CLIP-seq
MIRT1974403	hsa-miR-4775	CLIP-seq
MIRT1974404	hsa-miR-514	CLIP-seq
MIRT1974405	hsa-miR-514b-3p	CLIP-seq
MIRT1974406	hsa-miR-612	CLIP-seq
MIRT926201	hsa-miR-626	CLIP-seq
MIRT1974407	hsa-miR-98	CLIP-seq
MIRT1974385	hsa-let-7a	CLIP-seq
MIRT1974386	hsa-let-7b	CLIP-seq
MIRT1974387	hsa-let-7c	CLIP-seq
MIRT1974388	hsa-let-7d	CLIP-seq
MIRT1974389	hsa-let-7e	CLIP-seq
MIRT1974390	hsa-let-7f	CLIP-seq
MIRT1974391	hsa-let-7g	CLIP-seq
MIRT1974392	hsa-let-7i	CLIP-seq
MIRT1974394	hsa-miR-202	CLIP-seq
MIRT2209860	hsa-miR-203	CLIP-seq
MIRT2209861	hsa-miR-3652	CLIP-seq
MIRT2209862	hsa-miR-4430	CLIP-seq
MIRT2209863	hsa-miR-4432	CLIP-seq
MIRT1974398	hsa-miR-4458	CLIP-seq
MIRT1974399	hsa-miR-4461	CLIP-seq
MIRT2209864	hsa-miR-4488	CLIP-seq
MIRT2209865	hsa-miR-4492	CLIP-seq
MIRT2209866	hsa-miR-4498	CLIP-seq
MIRT2209867	hsa-miR-4499	CLIP-seq
MIRT1974400	hsa-miR-4500	CLIP-seq
MIRT2209868	hsa-miR-4638-3p	CLIP-seq
MIRT2209869	hsa-miR-4697-5p	CLIP-seq
MIRT2209870	hsa-miR-499-5p	CLIP-seq
MIRT1974404	hsa-miR-514	CLIP-seq
MIRT1974405	hsa-miR-514b-3p	CLIP-seq
MIRT2209871	hsa-miR-548g	CLIP-seq
MIRT2209872	hsa-miR-637	CLIP-seq
MIRT2209873	hsa-miR-642b	CLIP-seq
MIRT2209874	hsa-miR-762	CLIP-seq
MIRT1974407	hsa-miR-98	CLIP-seq
MIRT1974385	hsa-let-7a	CLIP-seq
MIRT1974386	hsa-let-7b	CLIP-seq
MIRT1974387	hsa-let-7c	CLIP-seq
MIRT1974388	hsa-let-7d	CLIP-seq
MIRT1974389	hsa-let-7e	CLIP-seq
MIRT1974390	hsa-let-7f	CLIP-seq
MIRT1974391	hsa-let-7g	CLIP-seq
MIRT1974392	hsa-let-7i	CLIP-seq
MIRT2386776	hsa-miR-1236	CLIP-seq
MIRT2386777	hsa-miR-145	CLIP-seq
MIRT2386778	hsa-miR-1825	CLIP-seq
MIRT2386779	hsa-miR-190	CLIP-seq
MIRT2386780	hsa-miR-190b	CLIP-seq
MIRT2386781	hsa-miR-199a-5p	CLIP-seq
MIRT2386782	hsa-miR-199b-5p	CLIP-seq
MIRT1974394	hsa-miR-202	CLIP-seq
MIRT1974398	hsa-miR-4458	CLIP-seq
MIRT1974399	hsa-miR-4461	CLIP-seq
MIRT1974400	hsa-miR-4500	CLIP-seq
MIRT1974404	hsa-miR-514	CLIP-seq
MIRT1974405	hsa-miR-514b-3p	CLIP-seq
MIRT2386783	hsa-miR-593	CLIP-seq
MIRT2209873	hsa-miR-642b	CLIP-seq
MIRT2386784	hsa-miR-654-3p	CLIP-seq
MIRT1974407	hsa-miR-98	CLIP-seq

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0034504	Process	Protein localization to nucleus	IBA
GO:0106310	Function	Protein serine kinase activity	IEA

MIM	HGNC	e!Ensembl
613167	19005	ENSG00000163673

Q9C098

Protein name

Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	356 → 613	Protein kinase domain	Domain

Sequence

MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
VILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKK
RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS

Sequence length

648

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Ovarian serous cystadenocarcinoma	Uncertain significance	rs539549840	RCV005937424

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Bipolar Disorder	Associate	40562893
Colorectal Neoplasms	Associate	28195176
Dendritic Cell Sarcoma Follicular	Associate	37991344
Infections	Associate	29272097
Inflammation	Associate	34315926
Melanoma	Associate	36353633, 37991344
Neoplasms	Associate	28195176, 36353633, 37991344
Urinary Bladder Neoplasms	Associate	36131933

DCLK3 (doublecortin like kinase 3)