RHPN2 (rhophilin Rho GTPase binding protein 2)

Gene

• Entrez ID: 85415
• Gene name: Rhophilin Rho GTPase binding protein 2
• Gene symbol: RHPN2
• Synonyms (NCBI Gene): P76RBE, RHOBP
• Chromosome: 19
• Chromosome location: 19q13.11
• Summary: This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by R

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT028291	hsa-miR-32-5p	Sequencing	20371350
MIRT048413	hsa-miR-100-5p	CLASH	23622248
MIRT736300	hsa-miR-146b-5p	Luciferase reporter assay, Western blotting, qRT-PCR, Flow cytometry	33877886
MIRT736301	hsa-miR-146a-5p	Luciferase reporter assay, Western blotting, qRT-PCR, Flow cytometry	33877886
MIRT1306283	hsa-let-7a	CLIP-seq
MIRT1306284	hsa-let-7b	CLIP-seq
MIRT1306285	hsa-let-7c	CLIP-seq
MIRT1306286	hsa-let-7d	CLIP-seq
MIRT1306287	hsa-let-7e	CLIP-seq
MIRT1306288	hsa-let-7f	CLIP-seq
MIRT1306289	hsa-let-7g	CLIP-seq
MIRT1306290	hsa-let-7i	CLIP-seq
MIRT1306291	hsa-miR-1228	CLIP-seq
MIRT1306292	hsa-miR-1273g	CLIP-seq
MIRT1306293	hsa-miR-1291	CLIP-seq
MIRT1306294	hsa-miR-1293	CLIP-seq
MIRT1306295	hsa-miR-1304	CLIP-seq
MIRT1306296	hsa-miR-15a	CLIP-seq
MIRT1306297	hsa-miR-15b	CLIP-seq
MIRT1306298	hsa-miR-16	CLIP-seq
MIRT1306299	hsa-miR-183	CLIP-seq
MIRT1306300	hsa-miR-195	CLIP-seq
MIRT1306301	hsa-miR-202	CLIP-seq
MIRT1306302	hsa-miR-2114	CLIP-seq
MIRT1306303	hsa-miR-2115	CLIP-seq
MIRT1306304	hsa-miR-24	CLIP-seq
MIRT1306305	hsa-miR-25	CLIP-seq
MIRT1306306	hsa-miR-28-5p	CLIP-seq
MIRT1306307	hsa-miR-2861	CLIP-seq
MIRT1306308	hsa-miR-3065-3p	CLIP-seq
MIRT1306309	hsa-miR-3117-5p	CLIP-seq
MIRT1306310	hsa-miR-3121-3p	CLIP-seq
MIRT1306311	hsa-miR-3122	CLIP-seq
MIRT1306312	hsa-miR-3127-5p	CLIP-seq
MIRT1306313	hsa-miR-3139	CLIP-seq
MIRT1306314	hsa-miR-3140-5p	CLIP-seq
MIRT1306315	hsa-miR-3145-3p	CLIP-seq
MIRT1306316	hsa-miR-3157-5p	CLIP-seq
MIRT1306317	hsa-miR-3160-3p	CLIP-seq
MIRT1306318	hsa-miR-3165	CLIP-seq
MIRT1306319	hsa-miR-3167	CLIP-seq
MIRT1306320	hsa-miR-32	CLIP-seq
MIRT1306321	hsa-miR-328	CLIP-seq
MIRT1306322	hsa-miR-3591-5p	CLIP-seq
MIRT1306323	hsa-miR-3606	CLIP-seq
MIRT1306324	hsa-miR-363	CLIP-seq
MIRT1306325	hsa-miR-3658	CLIP-seq
MIRT1306326	hsa-miR-367	CLIP-seq
MIRT1306327	hsa-miR-3671	CLIP-seq
MIRT1306328	hsa-miR-3689a-3p	CLIP-seq
MIRT1306329	hsa-miR-3689c	CLIP-seq
MIRT1306330	hsa-miR-380	CLIP-seq
MIRT1306331	hsa-miR-3913-5p	CLIP-seq
MIRT1306332	hsa-miR-3918	CLIP-seq
MIRT1306333	hsa-miR-3924	CLIP-seq
MIRT1306334	hsa-miR-3929	CLIP-seq
MIRT1306335	hsa-miR-3977	CLIP-seq
MIRT1306336	hsa-miR-421	CLIP-seq
MIRT1306337	hsa-miR-424	CLIP-seq
MIRT1306338	hsa-miR-4284	CLIP-seq
MIRT1306339	hsa-miR-4318	CLIP-seq
MIRT1306340	hsa-miR-4328	CLIP-seq
MIRT1306341	hsa-miR-4419b	CLIP-seq
MIRT1306342	hsa-miR-4458	CLIP-seq
MIRT1306343	hsa-miR-4477b	CLIP-seq
MIRT1306344	hsa-miR-4478	CLIP-seq
MIRT1306345	hsa-miR-4483	CLIP-seq
MIRT1306346	hsa-miR-4487	CLIP-seq
MIRT1306347	hsa-miR-4495	CLIP-seq
MIRT1306348	hsa-miR-4500	CLIP-seq
MIRT1306349	hsa-miR-4512	CLIP-seq
MIRT1306350	hsa-miR-4645-5p	CLIP-seq
MIRT1306351	hsa-miR-4662a-3p	CLIP-seq
MIRT1306352	hsa-miR-4673	CLIP-seq
MIRT1306353	hsa-miR-4691-3p	CLIP-seq
MIRT1306354	hsa-miR-4693-5p	CLIP-seq
MIRT1306355	hsa-miR-4709-5p	CLIP-seq
MIRT1306356	hsa-miR-4728-5p	CLIP-seq
MIRT1306357	hsa-miR-4729	CLIP-seq
MIRT1306358	hsa-miR-4735-5p	CLIP-seq
MIRT1306359	hsa-miR-4753-5p	CLIP-seq
MIRT1306360	hsa-miR-4755-3p	CLIP-seq
MIRT1306361	hsa-miR-485-5p	CLIP-seq
MIRT1306362	hsa-miR-497	CLIP-seq
MIRT1306363	hsa-miR-505	CLIP-seq
MIRT1306364	hsa-miR-516a-3p	CLIP-seq
MIRT1306365	hsa-miR-548c-3p	CLIP-seq
MIRT1306366	hsa-miR-558	CLIP-seq
MIRT1306367	hsa-miR-579	CLIP-seq
MIRT1306368	hsa-miR-587	CLIP-seq
MIRT1306369	hsa-miR-592	CLIP-seq
MIRT1306370	hsa-miR-597	CLIP-seq
MIRT1306371	hsa-miR-708	CLIP-seq
MIRT1306372	hsa-miR-766	CLIP-seq
MIRT1306373	hsa-miR-876-3p	CLIP-seq
MIRT1306374	hsa-miR-876-5p	CLIP-seq
MIRT1306375	hsa-miR-885-5p	CLIP-seq
MIRT1306376	hsa-miR-892a	CLIP-seq
MIRT1306377	hsa-miR-921	CLIP-seq
MIRT1306378	hsa-miR-922	CLIP-seq
MIRT1306379	hsa-miR-92a	CLIP-seq
MIRT1306380	hsa-miR-92b	CLIP-seq
MIRT1306381	hsa-miR-98	CLIP-seq
MIRT1306291	hsa-miR-1228	CLIP-seq
MIRT2090740	hsa-miR-1285	CLIP-seq
MIRT1306293	hsa-miR-1291	CLIP-seq
MIRT1306295	hsa-miR-1304	CLIP-seq
MIRT2090741	hsa-miR-154	CLIP-seq
MIRT1306296	hsa-miR-15a	CLIP-seq
MIRT1306297	hsa-miR-15b	CLIP-seq
MIRT1306298	hsa-miR-16	CLIP-seq
MIRT2090742	hsa-miR-1915	CLIP-seq
MIRT1306300	hsa-miR-195	CLIP-seq
MIRT1306306	hsa-miR-28-5p	CLIP-seq
MIRT1306309	hsa-miR-3117-5p	CLIP-seq
MIRT1306311	hsa-miR-3122	CLIP-seq
MIRT1306313	hsa-miR-3139	CLIP-seq
MIRT1306317	hsa-miR-3160-3p	CLIP-seq
MIRT1306319	hsa-miR-3167	CLIP-seq
MIRT2090743	hsa-miR-3180	CLIP-seq
MIRT2090744	hsa-miR-3180-3p	CLIP-seq
MIRT2090745	hsa-miR-3196	CLIP-seq
MIRT1306321	hsa-miR-328	CLIP-seq
MIRT2090746	hsa-miR-3616-3p	CLIP-seq
MIRT1306328	hsa-miR-3689a-3p	CLIP-seq
MIRT1306329	hsa-miR-3689c	CLIP-seq
MIRT2090747	hsa-miR-369-3p	CLIP-seq
MIRT2090748	hsa-miR-374a	CLIP-seq
MIRT2090749	hsa-miR-374b	CLIP-seq
MIRT2090750	hsa-miR-376a	CLIP-seq
MIRT2090751	hsa-miR-376b	CLIP-seq
MIRT1306331	hsa-miR-3913-5p	CLIP-seq
MIRT1306334	hsa-miR-3929	CLIP-seq
MIRT1306337	hsa-miR-424	CLIP-seq
MIRT2090752	hsa-miR-4307	CLIP-seq
MIRT1306341	hsa-miR-4419b	CLIP-seq
MIRT2090753	hsa-miR-4427	CLIP-seq
MIRT2090754	hsa-miR-4452	CLIP-seq
MIRT1306343	hsa-miR-4477b	CLIP-seq
MIRT1306344	hsa-miR-4478	CLIP-seq
MIRT2090755	hsa-miR-4488	CLIP-seq
MIRT2090756	hsa-miR-4680-3p	CLIP-seq
MIRT2090757	hsa-miR-4697-5p	CLIP-seq
MIRT2090758	hsa-miR-4726-3p	CLIP-seq
MIRT1306356	hsa-miR-4728-5p	CLIP-seq
MIRT1306358	hsa-miR-4735-5p	CLIP-seq
MIRT1306361	hsa-miR-485-5p	CLIP-seq
MIRT1306362	hsa-miR-497	CLIP-seq
MIRT1306365	hsa-miR-548c-3p	CLIP-seq
MIRT1306367	hsa-miR-579	CLIP-seq
MIRT2090759	hsa-miR-582-5p	CLIP-seq
MIRT2090760	hsa-miR-633	CLIP-seq
MIRT2090761	hsa-miR-640	CLIP-seq
MIRT2090762	hsa-miR-658	CLIP-seq
MIRT2090763	hsa-miR-665	CLIP-seq
MIRT1306371	hsa-miR-708	CLIP-seq
MIRT1306372	hsa-miR-766	CLIP-seq
MIRT1306374	hsa-miR-876-5p	CLIP-seq
MIRT1306378	hsa-miR-922	CLIP-seq
MIRT1306283	hsa-let-7a	CLIP-seq
MIRT1306284	hsa-let-7b	CLIP-seq
MIRT1306285	hsa-let-7c	CLIP-seq
MIRT1306286	hsa-let-7d	CLIP-seq
MIRT1306287	hsa-let-7e	CLIP-seq
MIRT1306288	hsa-let-7f	CLIP-seq
MIRT1306289	hsa-let-7g	CLIP-seq
MIRT1306290	hsa-let-7i	CLIP-seq
MIRT1306291	hsa-miR-1228	CLIP-seq
MIRT1306292	hsa-miR-1273g	CLIP-seq
MIRT2090740	hsa-miR-1285	CLIP-seq
MIRT2315409	hsa-miR-1287	CLIP-seq
MIRT1306294	hsa-miR-1293	CLIP-seq
MIRT2315410	hsa-miR-1302	CLIP-seq
MIRT1306295	hsa-miR-1304	CLIP-seq
MIRT2315411	hsa-miR-141	CLIP-seq
MIRT2090741	hsa-miR-154	CLIP-seq
MIRT1306296	hsa-miR-15a	CLIP-seq
MIRT1306297	hsa-miR-15b	CLIP-seq
MIRT1306298	hsa-miR-16	CLIP-seq
MIRT1306299	hsa-miR-183	CLIP-seq
MIRT2315412	hsa-miR-1910	CLIP-seq
MIRT2090742	hsa-miR-1915	CLIP-seq
MIRT1306300	hsa-miR-195	CLIP-seq
MIRT2315413	hsa-miR-200a	CLIP-seq
MIRT1306301	hsa-miR-202	CLIP-seq
MIRT1306302	hsa-miR-2114	CLIP-seq
MIRT1306303	hsa-miR-2115	CLIP-seq
MIRT1306304	hsa-miR-24	CLIP-seq
MIRT1306305	hsa-miR-25	CLIP-seq
MIRT1306308	hsa-miR-3065-3p	CLIP-seq
MIRT1306309	hsa-miR-3117-5p	CLIP-seq
MIRT1306310	hsa-miR-3121-3p	CLIP-seq
MIRT1306311	hsa-miR-3122	CLIP-seq
MIRT2315414	hsa-miR-3135b	CLIP-seq
MIRT1306314	hsa-miR-3140-5p	CLIP-seq
MIRT1306315	hsa-miR-3145-3p	CLIP-seq
MIRT1306316	hsa-miR-3157-5p	CLIP-seq
MIRT1306317	hsa-miR-3160-3p	CLIP-seq
MIRT1306318	hsa-miR-3165	CLIP-seq
MIRT1306319	hsa-miR-3167	CLIP-seq
MIRT2090743	hsa-miR-3180	CLIP-seq
MIRT2090744	hsa-miR-3180-3p	CLIP-seq
MIRT2090745	hsa-miR-3196	CLIP-seq
MIRT1306320	hsa-miR-32	CLIP-seq
MIRT2315415	hsa-miR-337-3p	CLIP-seq
MIRT1306322	hsa-miR-3591-5p	CLIP-seq
MIRT1306323	hsa-miR-3606	CLIP-seq
MIRT2315416	hsa-miR-3613-3p	CLIP-seq
MIRT2090746	hsa-miR-3616-3p	CLIP-seq
MIRT1306324	hsa-miR-363	CLIP-seq
MIRT1306325	hsa-miR-3658	CLIP-seq
MIRT2315417	hsa-miR-3661	CLIP-seq
MIRT1306326	hsa-miR-367	CLIP-seq
MIRT1306327	hsa-miR-3671	CLIP-seq
MIRT1306328	hsa-miR-3689a-3p	CLIP-seq
MIRT1306329	hsa-miR-3689c	CLIP-seq
MIRT2090747	hsa-miR-369-3p	CLIP-seq
MIRT2315418	hsa-miR-371-5p	CLIP-seq
MIRT2315419	hsa-miR-371b-5p	CLIP-seq
MIRT2090748	hsa-miR-374a	CLIP-seq
MIRT2090749	hsa-miR-374b	CLIP-seq
MIRT2090750	hsa-miR-376a	CLIP-seq
MIRT2090751	hsa-miR-376b	CLIP-seq
MIRT2315420	hsa-miR-3909	CLIP-seq
MIRT1306331	hsa-miR-3913-5p	CLIP-seq
MIRT2315421	hsa-miR-3926	CLIP-seq
MIRT1306334	hsa-miR-3929	CLIP-seq
MIRT1306335	hsa-miR-3977	CLIP-seq
MIRT1306336	hsa-miR-421	CLIP-seq
MIRT1306337	hsa-miR-424	CLIP-seq
MIRT2315422	hsa-miR-4252	CLIP-seq
MIRT2315423	hsa-miR-4256	CLIP-seq
MIRT1306338	hsa-miR-4284	CLIP-seq
MIRT2315424	hsa-miR-4298	CLIP-seq
MIRT2315425	hsa-miR-4325	CLIP-seq
MIRT1306340	hsa-miR-4328	CLIP-seq
MIRT1306341	hsa-miR-4419b	CLIP-seq
MIRT2090754	hsa-miR-4452	CLIP-seq
MIRT1306342	hsa-miR-4458	CLIP-seq
MIRT2315426	hsa-miR-4476	CLIP-seq
MIRT1306343	hsa-miR-4477b	CLIP-seq
MIRT1306344	hsa-miR-4478	CLIP-seq
MIRT1306345	hsa-miR-4483	CLIP-seq
MIRT1306346	hsa-miR-4487	CLIP-seq
MIRT2090755	hsa-miR-4488	CLIP-seq
MIRT1306348	hsa-miR-4500	CLIP-seq
MIRT1306350	hsa-miR-4645-5p	CLIP-seq
MIRT1306351	hsa-miR-4662a-3p	CLIP-seq
MIRT1306352	hsa-miR-4673	CLIP-seq
MIRT1306353	hsa-miR-4691-3p	CLIP-seq
MIRT2090757	hsa-miR-4697-5p	CLIP-seq
MIRT1306355	hsa-miR-4709-5p	CLIP-seq
MIRT2090758	hsa-miR-4726-3p	CLIP-seq
MIRT1306356	hsa-miR-4728-5p	CLIP-seq
MIRT1306357	hsa-miR-4729	CLIP-seq
MIRT1306358	hsa-miR-4735-5p	CLIP-seq
MIRT1306359	hsa-miR-4753-5p	CLIP-seq
MIRT1306360	hsa-miR-4755-3p	CLIP-seq
MIRT2315427	hsa-miR-4760-5p	CLIP-seq
MIRT1306361	hsa-miR-485-5p	CLIP-seq
MIRT1306362	hsa-miR-497	CLIP-seq
MIRT1306363	hsa-miR-505	CLIP-seq
MIRT1306364	hsa-miR-516a-3p	CLIP-seq
MIRT1306365	hsa-miR-548c-3p	CLIP-seq
MIRT2315428	hsa-miR-548s	CLIP-seq
MIRT1306366	hsa-miR-558	CLIP-seq
MIRT2315429	hsa-miR-569	CLIP-seq
MIRT1306367	hsa-miR-579	CLIP-seq
MIRT2090759	hsa-miR-582-5p	CLIP-seq
MIRT1306368	hsa-miR-587	CLIP-seq
MIRT2315430	hsa-miR-631	CLIP-seq
MIRT2090760	hsa-miR-633	CLIP-seq
MIRT2090761	hsa-miR-640	CLIP-seq
MIRT2090762	hsa-miR-658	CLIP-seq
MIRT2090763	hsa-miR-665	CLIP-seq
MIRT1306372	hsa-miR-766	CLIP-seq
MIRT2315431	hsa-miR-802	CLIP-seq
MIRT1306373	hsa-miR-876-3p	CLIP-seq
MIRT1306374	hsa-miR-876-5p	CLIP-seq
MIRT1306375	hsa-miR-885-5p	CLIP-seq
MIRT1306376	hsa-miR-892a	CLIP-seq
MIRT1306377	hsa-miR-921	CLIP-seq
MIRT1306379	hsa-miR-92a	CLIP-seq
MIRT1306380	hsa-miR-92b	CLIP-seq
MIRT1306381	hsa-miR-98	CLIP-seq
MIRT1306291	hsa-miR-1228	CLIP-seq
MIRT1306294	hsa-miR-1293	CLIP-seq
MIRT1306304	hsa-miR-24	CLIP-seq
MIRT1306309	hsa-miR-3117-5p	CLIP-seq
MIRT1306311	hsa-miR-3122	CLIP-seq
MIRT1306322	hsa-miR-3591-5p	CLIP-seq
MIRT1306323	hsa-miR-3606	CLIP-seq
MIRT1306328	hsa-miR-3689a-3p	CLIP-seq
MIRT1306329	hsa-miR-3689c	CLIP-seq
MIRT1306331	hsa-miR-3913-5p	CLIP-seq
MIRT1306334	hsa-miR-3929	CLIP-seq
MIRT1306338	hsa-miR-4284	CLIP-seq
MIRT1306340	hsa-miR-4328	CLIP-seq
MIRT1306341	hsa-miR-4419b	CLIP-seq
MIRT1306344	hsa-miR-4478	CLIP-seq
MIRT1306345	hsa-miR-4483	CLIP-seq
MIRT1306356	hsa-miR-4728-5p	CLIP-seq
MIRT1306358	hsa-miR-4735-5p	CLIP-seq
MIRT1306361	hsa-miR-485-5p	CLIP-seq
MIRT1306377	hsa-miR-921	CLIP-seq
MIRT1306294	hsa-miR-1293	CLIP-seq
MIRT1306295	hsa-miR-1304	CLIP-seq
MIRT1306311	hsa-miR-3122	CLIP-seq
MIRT1306318	hsa-miR-3165	CLIP-seq
MIRT1306328	hsa-miR-3689a-3p	CLIP-seq
MIRT1306329	hsa-miR-3689c	CLIP-seq
MIRT1306331	hsa-miR-3913-5p	CLIP-seq
MIRT1306334	hsa-miR-3929	CLIP-seq
MIRT1306341	hsa-miR-4419b	CLIP-seq
MIRT1306344	hsa-miR-4478	CLIP-seq
MIRT1306345	hsa-miR-4483	CLIP-seq
MIRT1306356	hsa-miR-4728-5p	CLIP-seq
MIRT1306361	hsa-miR-485-5p	CLIP-seq
MIRT1306367	hsa-miR-579	CLIP-seq
MIRT1306294	hsa-miR-1293	CLIP-seq
MIRT1306295	hsa-miR-1304	CLIP-seq
MIRT1306311	hsa-miR-3122	CLIP-seq
MIRT1306318	hsa-miR-3165	CLIP-seq
MIRT2611692	hsa-miR-3617	CLIP-seq
MIRT1306328	hsa-miR-3689a-3p	CLIP-seq
MIRT1306329	hsa-miR-3689c	CLIP-seq
MIRT1306331	hsa-miR-3913-5p	CLIP-seq
MIRT1306334	hsa-miR-3929	CLIP-seq
MIRT1306341	hsa-miR-4419b	CLIP-seq
MIRT1306344	hsa-miR-4478	CLIP-seq
MIRT1306345	hsa-miR-4483	CLIP-seq
MIRT1306356	hsa-miR-4728-5p	CLIP-seq
MIRT1306361	hsa-miR-485-5p	CLIP-seq
MIRT1306367	hsa-miR-579	CLIP-seq
MIRT2611693	hsa-miR-641	CLIP-seq
MIRT1306294	hsa-miR-1293	CLIP-seq
MIRT1306295	hsa-miR-1304	CLIP-seq
MIRT1306311	hsa-miR-3122	CLIP-seq
MIRT1306318	hsa-miR-3165	CLIP-seq
MIRT1306328	hsa-miR-3689a-3p	CLIP-seq
MIRT1306329	hsa-miR-3689c	CLIP-seq
MIRT1306331	hsa-miR-3913-5p	CLIP-seq
MIRT1306334	hsa-miR-3929	CLIP-seq
MIRT1306341	hsa-miR-4419b	CLIP-seq
MIRT1306344	hsa-miR-4478	CLIP-seq
MIRT1306345	hsa-miR-4483	CLIP-seq
MIRT1306356	hsa-miR-4728-5p	CLIP-seq
MIRT1306361	hsa-miR-485-5p	CLIP-seq
MIRT1306367	hsa-miR-579	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003094	Process	Glomerular filtration	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	25071083
GO:0007165	Process	Signal transduction	IEA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0051497	Process	Negative regulation of stress fiber assembly	IBA
GO:0051497	Process	Negative regulation of stress fiber assembly	IDA	25071083

Other IDs

• MIM: 617932
• HGNC: 19974
• e!Ensembl: ENSG00000131941

Protein

• UniProt ID: Q8IUC4
• Protein name: Rhophilin-2 (76 kDa RhoB effector protein) (GTP-Rho-binding protein 2) (p76RBE)
• Protein function: Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.
• PDB: 2VSV
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02185	HR1	39 → 102	Hr1 repeat	Family
  PF03097	BRO1	112 → 516	BRO1-like domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver. {ECO:0000269|PubMed:12221077, ECO:0000269|PubMed:12473120}.
• Sequence:

  MTDALLPAAPQPLEKENDGYFRKGCNPLAQTGRSKLQNQRAALNQQILKAVRMRTGAENL
  LKVATNSKVREQVRLELSFVNSDLQMLKEELEGLNISVGVYQNTEEAFTIPLIPLGLKET
  KDVDFAVVLKDFILEHYSEDGYLYEDEIADLMDLRQACRTPSRDEAGVELLMTYFIQLGF
  VESRFFPPTRQMGLLFTWYDSLTGVPVSQQNLLLEKASVLFNTGALYTQIGTRCDRQTQA
  GLESAIDAFQRAAGVLNYLKDTFTHTPSYDMSPAMLSVLVKMMLAQAQESVFEKISLPGI
  RNEFFMLVKVAQEAAKVGEVYQQLHAAMSQAPVKENIPYSWASLACVKAHHYAALAHYFT
  AILLIDHQVKPGTDLDHQEKCLSQLYDHMPEGLTPLATLKNDQQRRQLGKSHLRRAMAHH
  EESVREASLCKKLRSIEVLQKVLCAAQERSRLTYAQHQEEDDLLNLIDAPSVVAKTEQEV
  DIILPQFSKLTVTDFFQKLGPLSVFSANKRWTPPRSIRFTAEEGDLGFTLRGNAPVQVHF
  LDPYCSASVAGAREGDYIVSIQLVDCKWLTLSEVMKLLKSFGEDEIEMKVVSLLDSTSSM
  HNKSATYSVGMQKTYSMICLAIDDDDKTDKTKKISKKLSFLSWGTNKNRQKSASTLCLPS
  VGAARPQVKKKLPSPFSLLNSDSSWY

• Sequence length: 686

Pathways

Reactome:

RHO GTPases Activate Rhotekin and Rhophilins