Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8522
Gene name Gene Name - the full gene name approved by the HGNC.
Growth arrest specific 7
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GAS7
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17p13.1
Summary Summary of gene provided in NCBI Entrez Gene.
Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021949 hsa-miR-128-3p Microarray 17612493
MIRT526756 hsa-miR-6837-3p PAR-CLIP 22012620
MIRT526755 hsa-miR-3124-3p PAR-CLIP 22012620
MIRT526754 hsa-miR-337-3p PAR-CLIP 22012620
MIRT526753 hsa-miR-202-5p PAR-CLIP 22012620
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 31515488
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005856 Component Cytoskeleton IBA 21873635
GO:0005884 Component Actin filament IBA 21873635
GO:0005886 Component Plasma membrane IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603127 4169 ENSG00000007237
Protein
UniProt ID O60861
Protein name Growth arrest-specific protein 7 (GAS-7)
Protein function May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
PDB 2LX7 , 2YSH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14604 SH3_9 8 58 Variant SH3 domain Domain
PF00397 WW 79 108 WW domain Domain
PF16623 WW_FCH_linker 109 201 Disordered
PF00611 FCH 219 291 Fes/CIP4, and EFC/F-BAR homology domain Family
Sequence
MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL
EKPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGS
HRSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVT
FPHPDTMPEQQLLKPTEWSYC
DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEF
IRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLK
FSAKLHSEV
EKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIK
LSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIR
QHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI
Sequence length 476
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Obesity Obesity rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562
View all (27 more)
19270708
Unknown
Disease term Disease name Evidence References Source
Glaucoma Glaucoma GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 25287138
Colorectal Neoplasms Associate 21298349, 24441198
Glaucoma Open Angle Associate 25414181, 25637523, 29261660, 35400990, 38240248
Leukemia Associate 10706619
Leukemia Myeloid Acute Associate 10706619, 31925702
Lung Neoplasms Associate 28475688
Melanoma Associate 26489459
Neoplasms Associate 15614045, 24441198, 25287138, 31925702
Neoplasms Inhibit 28475688, 28771526
Neoplasms Stimulate 36177918