CGNL1 (cingulin like 1)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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84952 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Cingulin like 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CGNL1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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JACOP, PCING |
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Chromosome
Chromosome number
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15 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q21.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chro |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q0VF96 | |||||||||||||||
| Protein name | Cingulin-like protein 1 (Junction-associated coiled-coil protein) (Paracingulin) | |||||||||||||||
| Protein function | May be involved in anchoring the apical junctional complex, especially tight junctions, to actin-based cytoskeletons. | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Smooth muscle, spleen, testis, fetal brain, amygdala, corpus callosum, cerebellum, thalamus and subthalamic nucleus of adult brain. {ECO:0000269|PubMed:11214970}. | |||||||||||||||
| Sequence | ||||||||||||||||
| Sequence length | 1302 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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