CORO6 (coronin 6)

Gene

• Entrez ID: 84940
• Gene name: Coronin 6
• Gene symbol: CORO6
• Synonyms (NCBI Gene): ClipinE
• Chromosome: 17
• Chromosome location: 17q11.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT025915	hsa-miR-7-5p	Microarray	19073608
MIRT738269	hsa-miR-1252	CLIP-seq
MIRT904748	hsa-miR-1275	CLIP-seq
MIRT738271	hsa-miR-339-5p	CLIP-seq
MIRT904749	hsa-miR-34a	CLIP-seq
MIRT904750	hsa-miR-34c-5p	CLIP-seq
MIRT738270	hsa-miR-3978	CLIP-seq
MIRT904751	hsa-miR-4302	CLIP-seq
MIRT904752	hsa-miR-4488	CLIP-seq
MIRT904753	hsa-miR-449a	CLIP-seq
MIRT904754	hsa-miR-449b	CLIP-seq
MIRT904755	hsa-miR-4665-5p	CLIP-seq
MIRT904756	hsa-miR-4697-5p	CLIP-seq
MIRT904757	hsa-miR-486-3p	CLIP-seq
MIRT738269	hsa-miR-1252	CLIP-seq
MIRT738271	hsa-miR-339-5p	CLIP-seq
MIRT738270	hsa-miR-3978	CLIP-seq
MIRT738269	hsa-miR-1252	CLIP-seq
MIRT738271	hsa-miR-339-5p	CLIP-seq
MIRT738270	hsa-miR-3978	CLIP-seq
MIRT738269	hsa-miR-1252	CLIP-seq
MIRT2204138	hsa-miR-3155	CLIP-seq
MIRT2204139	hsa-miR-3155b	CLIP-seq
MIRT2204140	hsa-miR-323b-3p	CLIP-seq
MIRT738271	hsa-miR-339-5p	CLIP-seq
MIRT738270	hsa-miR-3978	CLIP-seq
MIRT2204141	hsa-miR-4258	CLIP-seq
MIRT2204142	hsa-miR-4690-3p	CLIP-seq
MIRT2204143	hsa-miR-484	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956
GO:0007015	Process	Actin filament organization	IBA	21873635
GO:0016477	Process	Cell migration	IBA	21873635
GO:0051015	Function	Actin filament binding	IBA	21873635

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6QEF8
• Protein name: Coronin-6 (Coronin-like protein E) (Clipin-E)
• PDB: 7KYX
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08953	DUF1899	4 → 69	Domain of unknown function (DUF1899)	Domain
  PF00400	WD40	72 → 110	WD domain, G-beta repeat	Repeat
  PF00400	WD40	121 → 160	WD domain, G-beta repeat	Repeat
  PF12894	ANAPC4_WD40	170 → 227	Anaphase-promoting complex subunit 4 WD40 domain	Repeat
  PF16300	WD40_4	344 → 386		Repeat

• Sequence:

  MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFI
  VLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNI
  TEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHS
  VCWNSNGSLLATTCKDKTLRIIDPRKGQVVAEQARPHEGARPLRAVFTADGKLLSTGFSR
  MSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEP
  PFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQD
  DLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPR
  RSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCELVDGTD

• Sequence length: 472

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Coronary artery disease	Coronary Artery Disease	rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537	29212778

Associations from Text Mining
Disease Name	Relationship Type	References
Heart Diseases	Associate	35062960
Lymphatic Metastasis	Associate	32934959