Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	84930
Gene name	Microtubule associated serine/threonine kinase like
Gene symbol	MASTL
Synonyms (NCBI Gene)	GREATWALLGWGWLMAST-LTHC2
Chromosome	10
Chromosome location	10p12.1
Summary	This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for

243

Show/Hide all (243)

miRTarBase ID	miRNA	Experiments	Reference
MIRT021059	hsa-miR-155-5p	Reporter assay;Other	18668040
MIRT021059	hsa-miR-155-5p	Reporter assay;Other	20584899
MIRT047078	hsa-miR-183-5p	CLASH	23622248
MIRT126555	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT126560	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT126559	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT126577	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT126585	hsa-miR-3666	HITS-CLIP	23824327
MIRT126582	hsa-miR-4295	HITS-CLIP	23824327
MIRT126574	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT663529	hsa-miR-652-3p	HITS-CLIP	23824327
MIRT663528	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT663527	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT663526	hsa-miR-215-3p	HITS-CLIP	23824327
MIRT663525	hsa-miR-3135b	HITS-CLIP	23824327
MIRT663524	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT663523	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT637419	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT663522	hsa-miR-566	HITS-CLIP	23824327
MIRT663521	hsa-miR-3652	HITS-CLIP	23824327
MIRT663520	hsa-miR-4430	HITS-CLIP	23824327
MIRT663519	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT663518	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT663517	hsa-miR-8057	HITS-CLIP	23824327
MIRT540375	hsa-miR-4438	HITS-CLIP	23824327
MIRT637419	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT637418	hsa-miR-3199	HITS-CLIP	23824327
MIRT637417	hsa-miR-8052	HITS-CLIP	23824327
MIRT637416	hsa-miR-365a-5p	HITS-CLIP	23824327
MIRT637415	hsa-miR-365b-5p	HITS-CLIP	23824327
MIRT540364	hsa-miR-5095	HITS-CLIP	23824327
MIRT540363	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT566814	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT566813	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT262178	hsa-miR-4795-3p	PAR-CLIP	20371350
MIRT566812	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT556234	hsa-miR-618	PAR-CLIP	21572407
MIRT556233	hsa-miR-6074	PAR-CLIP	21572407
MIRT126592	hsa-miR-4764-3p	PAR-CLIP	21572407
MIRT110538	hsa-miR-3157-5p	PAR-CLIP	21572407
MIRT126569	hsa-miR-552-5p	PAR-CLIP	21572407
MIRT126554	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT126558	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT126547	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT126550	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT126562	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT126566	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT126564	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT126551	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT540387	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT540386	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT540385	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT540384	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT540383	hsa-miR-302e	PAR-CLIP	21572407
MIRT540382	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT540381	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT540380	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT540379	hsa-miR-520b	PAR-CLIP	21572407
MIRT540378	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT540377	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT540376	hsa-miR-520e	PAR-CLIP	21572407
MIRT540375	hsa-miR-4438	PAR-CLIP	21572407
MIRT540374	hsa-miR-512-3p	PAR-CLIP	21572407
MIRT540373	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT540372	hsa-miR-520g-3p	PAR-CLIP	21572407
MIRT540371	hsa-miR-520h	PAR-CLIP	21572407
MIRT540370	hsa-miR-186-3p	PAR-CLIP	21572407
MIRT540369	hsa-miR-150-5p	PAR-CLIP	21572407
MIRT540368	hsa-miR-5186	PAR-CLIP	21572407
MIRT540367	hsa-miR-4663	PAR-CLIP	21572407
MIRT540366	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT540365	hsa-miR-8077	PAR-CLIP	21572407
MIRT540364	hsa-miR-5095	PAR-CLIP	21572407
MIRT540363	hsa-miR-7151-3p	PAR-CLIP	21572407
MIRT126558	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT021059	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT126550	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT126558	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT021059	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT126547	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT126562	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT126551	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT126566	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT126550	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT126555	hsa-miR-130a-3p	HITS-CLIP	23824327
MIRT126560	hsa-miR-130b-3p	HITS-CLIP	23824327
MIRT126559	hsa-miR-301a-3p	HITS-CLIP	23824327
MIRT126577	hsa-miR-301b-3p	HITS-CLIP	23824327
MIRT126585	hsa-miR-3666	HITS-CLIP	23824327
MIRT126582	hsa-miR-4295	HITS-CLIP	23824327
MIRT126574	hsa-miR-454-3p	HITS-CLIP	23824327
MIRT663529	hsa-miR-652-3p	HITS-CLIP	23824327
MIRT663528	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT663527	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT663526	hsa-miR-215-3p	HITS-CLIP	23824327
MIRT663525	hsa-miR-3135b	HITS-CLIP	23824327
MIRT663524	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT663523	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT637419	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT663522	hsa-miR-566	HITS-CLIP	23824327
MIRT663521	hsa-miR-3652	HITS-CLIP	23824327
MIRT663520	hsa-miR-4430	HITS-CLIP	23824327
MIRT663519	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT663518	hsa-miR-106a-3p	HITS-CLIP	23824327
MIRT663517	hsa-miR-8057	HITS-CLIP	23824327
MIRT540375	hsa-miR-4438	HITS-CLIP	23824327
MIRT637419	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT637418	hsa-miR-3199	HITS-CLIP	23824327
MIRT637417	hsa-miR-8052	HITS-CLIP	23824327
MIRT637416	hsa-miR-365a-5p	HITS-CLIP	23824327
MIRT637415	hsa-miR-365b-5p	HITS-CLIP	23824327
MIRT540364	hsa-miR-5095	HITS-CLIP	23824327
MIRT540363	hsa-miR-7151-3p	HITS-CLIP	23824327
MIRT566814	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT566813	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT262178	hsa-miR-4795-3p	PAR-CLIP	20371350
MIRT566812	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT556234	hsa-miR-618	PAR-CLIP	21572407
MIRT556233	hsa-miR-6074	PAR-CLIP	21572407
MIRT126592	hsa-miR-4764-3p	PAR-CLIP	21572407
MIRT110538	hsa-miR-3157-5p	PAR-CLIP	21572407
MIRT126569	hsa-miR-552-5p	PAR-CLIP	21572407
MIRT126554	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT126558	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT126547	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT126550	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT126562	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT126566	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT126564	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT126551	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT540387	hsa-miR-302a-3p	PAR-CLIP	21572407
MIRT540386	hsa-miR-302b-3p	PAR-CLIP	21572407
MIRT540385	hsa-miR-302c-3p	PAR-CLIP	21572407
MIRT540384	hsa-miR-302d-3p	PAR-CLIP	21572407
MIRT540383	hsa-miR-302e	PAR-CLIP	21572407
MIRT540382	hsa-miR-372-3p	PAR-CLIP	21572407
MIRT540381	hsa-miR-373-3p	PAR-CLIP	21572407
MIRT540380	hsa-miR-520a-3p	PAR-CLIP	21572407
MIRT540379	hsa-miR-520b	PAR-CLIP	21572407
MIRT540378	hsa-miR-520c-3p	PAR-CLIP	21572407
MIRT540377	hsa-miR-520d-3p	PAR-CLIP	21572407
MIRT540376	hsa-miR-520e	PAR-CLIP	21572407
MIRT540375	hsa-miR-4438	PAR-CLIP	21572407
MIRT540374	hsa-miR-512-3p	PAR-CLIP	21572407
MIRT540373	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT540372	hsa-miR-520g-3p	PAR-CLIP	21572407
MIRT540371	hsa-miR-520h	PAR-CLIP	21572407
MIRT540370	hsa-miR-186-3p	PAR-CLIP	21572407
MIRT540369	hsa-miR-150-5p	PAR-CLIP	21572407
MIRT540368	hsa-miR-5186	PAR-CLIP	21572407
MIRT540367	hsa-miR-4663	PAR-CLIP	21572407
MIRT540366	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT540365	hsa-miR-8077	PAR-CLIP	21572407
MIRT540364	hsa-miR-5095	PAR-CLIP	21572407
MIRT540363	hsa-miR-7151-3p	PAR-CLIP	21572407
MIRT1133326	hsa-miR-106a	CLIP-seq
MIRT1133327	hsa-miR-106b	CLIP-seq
MIRT1133328	hsa-miR-1304	CLIP-seq
MIRT1133329	hsa-miR-130a	CLIP-seq
MIRT1133330	hsa-miR-130b	CLIP-seq
MIRT1133331	hsa-miR-142-5p	CLIP-seq
MIRT1133332	hsa-miR-17	CLIP-seq
MIRT1133333	hsa-miR-2052	CLIP-seq
MIRT1133334	hsa-miR-20a	CLIP-seq
MIRT1133335	hsa-miR-20b	CLIP-seq
MIRT1133336	hsa-miR-24	CLIP-seq
MIRT1133337	hsa-miR-301a	CLIP-seq
MIRT1133338	hsa-miR-301b	CLIP-seq
MIRT1133339	hsa-miR-3150b-3p	CLIP-seq
MIRT1133340	hsa-miR-3609	CLIP-seq
MIRT1133341	hsa-miR-3646	CLIP-seq
MIRT1133342	hsa-miR-3677-5p	CLIP-seq
MIRT1133343	hsa-miR-3909	CLIP-seq
MIRT1133344	hsa-miR-3977	CLIP-seq
MIRT1133345	hsa-miR-4257	CLIP-seq
MIRT1133346	hsa-miR-4284	CLIP-seq
MIRT1133347	hsa-miR-4328	CLIP-seq
MIRT1133348	hsa-miR-454	CLIP-seq
MIRT1133349	hsa-miR-4639-3p	CLIP-seq
MIRT1133350	hsa-miR-4662a-3p	CLIP-seq
MIRT1133351	hsa-miR-4699-5p	CLIP-seq
MIRT1133352	hsa-miR-4709-3p	CLIP-seq
MIRT1133353	hsa-miR-4735-5p	CLIP-seq
MIRT1133354	hsa-miR-4775	CLIP-seq
MIRT1133355	hsa-miR-4784	CLIP-seq
MIRT1133356	hsa-miR-4796-3p	CLIP-seq
MIRT1133357	hsa-miR-519a	CLIP-seq
MIRT1133358	hsa-miR-519b-3p	CLIP-seq
MIRT1133359	hsa-miR-519c-3p	CLIP-seq
MIRT1133360	hsa-miR-519d	CLIP-seq
MIRT1133361	hsa-miR-548ah	CLIP-seq
MIRT1133362	hsa-miR-577	CLIP-seq
MIRT1133363	hsa-miR-582-5p	CLIP-seq
MIRT1133364	hsa-miR-590-3p	CLIP-seq
MIRT1133365	hsa-miR-93	CLIP-seq
MIRT1133326	hsa-miR-106a	CLIP-seq
MIRT1133327	hsa-miR-106b	CLIP-seq
MIRT1133329	hsa-miR-130a	CLIP-seq
MIRT1133330	hsa-miR-130b	CLIP-seq
MIRT1133331	hsa-miR-142-5p	CLIP-seq
MIRT1133332	hsa-miR-17	CLIP-seq
MIRT1133334	hsa-miR-20a	CLIP-seq
MIRT1133335	hsa-miR-20b	CLIP-seq
MIRT1133337	hsa-miR-301a	CLIP-seq
MIRT1133338	hsa-miR-301b	CLIP-seq
MIRT1133340	hsa-miR-3609	CLIP-seq
MIRT1133344	hsa-miR-3977	CLIP-seq
MIRT1133347	hsa-miR-4328	CLIP-seq
MIRT1133348	hsa-miR-454	CLIP-seq
MIRT1133356	hsa-miR-4796-3p	CLIP-seq
MIRT1133357	hsa-miR-519a	CLIP-seq
MIRT1133358	hsa-miR-519b-3p	CLIP-seq
MIRT1133359	hsa-miR-519c-3p	CLIP-seq
MIRT1133360	hsa-miR-519d	CLIP-seq
MIRT1133361	hsa-miR-548ah	CLIP-seq
MIRT1133365	hsa-miR-93	CLIP-seq
MIRT1133326	hsa-miR-106a	CLIP-seq
MIRT1133327	hsa-miR-106b	CLIP-seq
MIRT1133328	hsa-miR-1304	CLIP-seq
MIRT1133329	hsa-miR-130a	CLIP-seq
MIRT1133330	hsa-miR-130b	CLIP-seq
MIRT1133331	hsa-miR-142-5p	CLIP-seq
MIRT1133332	hsa-miR-17	CLIP-seq
MIRT1133333	hsa-miR-2052	CLIP-seq
MIRT1133334	hsa-miR-20a	CLIP-seq
MIRT1133335	hsa-miR-20b	CLIP-seq
MIRT1133337	hsa-miR-301a	CLIP-seq
MIRT1133338	hsa-miR-301b	CLIP-seq
MIRT1133340	hsa-miR-3609	CLIP-seq
MIRT1133344	hsa-miR-3977	CLIP-seq
MIRT2267974	hsa-miR-410	CLIP-seq
MIRT1133347	hsa-miR-4328	CLIP-seq
MIRT1133348	hsa-miR-454	CLIP-seq
MIRT1133350	hsa-miR-4662a-3p	CLIP-seq
MIRT1133356	hsa-miR-4796-3p	CLIP-seq
MIRT1133357	hsa-miR-519a	CLIP-seq
MIRT1133358	hsa-miR-519b-3p	CLIP-seq
MIRT1133359	hsa-miR-519c-3p	CLIP-seq
MIRT1133360	hsa-miR-519d	CLIP-seq
MIRT1133361	hsa-miR-548ah	CLIP-seq
MIRT1133362	hsa-miR-577	CLIP-seq
MIRT1133363	hsa-miR-582-5p	CLIP-seq
MIRT1133365	hsa-miR-93	CLIP-seq

Show/Hide all (33)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000086	Process	G2/M transition of mitotic cell cycle	IMP	20538976, 20818157
GO:0000166	Function	Nucleotide binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	20538976
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	TAS
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	20538976, 20818157
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	20538976
GO:0005813	Component	Centrosome	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0006974	Process	DNA damage response	ISS
GO:0007147	Process	Female meiosis II	IEA
GO:0007346	Process	Regulation of mitotic cell cycle	IBA
GO:0007346	Process	Regulation of mitotic cell cycle	TAS
GO:0015630	Component	Microtubule cytoskeleton	IBA
GO:0016301	Function	Kinase activity	IDA	20818157
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0032154	Component	Cleavage furrow	IDA	20538976, 20818157
GO:0032154	Component	Cleavage furrow	IEA
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0044325	Function	Transmembrane transporter binding	IEA
GO:0051301	Process	Cell division	IEA
GO:0051721	Function	Protein phosphatase 2A binding	ISS
GO:0051726	Process	Regulation of cell cycle	IMP	20818157
GO:0106310	Function	Protein serine kinase activity	IEA

MIM	HGNC	e!Ensembl
608221	19042	ENSG00000120539

Q96GX5

Protein name

Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L)

Protein function

Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance (PubMed:19680222). Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit P

PDB

5LOH , 8V5H

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	35 → 202	Protein kinase domain	Domain
PF00069	Pkinase	727 → 835	Protein kinase domain	Domain

Sequence

MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
ENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL

Sequence length

879

Interactions

View interactions

	Reactome
			MASTL Facilitates Mitotic Progression

110

Show/Hide Unknown Diseases (6)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Adrenocortical carcinoma, hereditary	Uncertain significance	rs747762064	RCV005913700
Autosomal dominant thrombocytopenia	Uncertain significance	rs1239580692	RCV002244251
MASTL-related disorder	Likely benign; Uncertain significance; Benign; Conflicting classifications of pathogenicity	rs200461088, rs2539969168, rs2539708321, rs537654014, rs1012781973, rs141882356, rs142221261, rs144174245, rs767592505, rs146116709, rs746804927, rs756961236, rs148839815, rs144503451, rs146165894 View all (4 more)	RCV003417126 RCV003402283 RCV003400404 RCV003410580 RCV003391303 RCV003924007 RCV003902221 RCV003904662 RCV003916823 RCV003976804 RCV003983520 RCV003959444 RCV003967862 RCV003953474 RCV003918683 RCV003973075 RCV003945814 RCV003918688 RCV003938448
Scimitar anomaly, multiple cardiac malformations, and craniofacial and central nervous system abnormalities	Uncertain significance	rs2539964632	RCV002466943
Thrombocytopenia	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	rs7919803, rs7907981, rs7907988, rs151176548, rs56204835, rs7068375, rs36121140, rs1981296, rs3802526, rs41282228, rs10741130, rs10764686, rs886046952, rs41282214, rs886046955 View all (59 more)	RCV001106116 RCV000265571 RCV000323031 RCV001106117 RCV000323174 RCV000283283 RCV000334567 RCV000364431 RCV000404316 RCV000361095 RCV000372462 RCV000296331 RCV000285992 RCV000343410 RCV000312082 RCV000261910 RCV000380017 RCV000338217 RCV000374215 RCV000407875 RCV000306486 RCV000266538 RCV000262564 RCV000332560 RCV000348212 RCV000391324 RCV000354245 RCV000300651 RCV000357922 RCV000377754 RCV000279577 RCV000313648 RCV000321165 RCV000387040 RCV000293253 RCV000403931 RCV000357279 RCV000381640 RCV000289925 RCV000347260 RCV000393935 RCV000350832 RCV000296987 RCV000268125 RCV000407871 RCV000349549 RCV000309782 RCV000317769 RCV001106207 RCV001105157 RCV001106118 RCV001108329 RCV001103149 RCV001103151 RCV001103152 RCV001103153 RCV001105059 RCV001105060 RCV001105061 RCV001105062 RCV001105063 RCV001106206 RCV001106208 RCV001108423 RCV001108424 RCV001108425 RCV001108426 RCV001108427 RCV001103243 RCV001103244 RCV001103245 RCV001105158 RCV001105159 RCV001103150
Thrombocytopenia 2	Uncertain significance; Benign; Likely benign	rs28941470, rs535159862, rs138288481	RCV000002573 RCV000714836 RCV002466596

Show/Hide Text Mining Associations (13)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Breast Neoplasms	Associate	28617547, 29976159, 32311005
Calcinosis Cutis	Stimulate	28617547
Carcinogenesis	Associate	30068336, 37508547
Chromosomal Instability	Associate	36787737
Colorectal Neoplasms	Associate	30068336, 37508547
Endometrial Neoplasms	Associate	33627787
Melanoma	Associate	31733171
Neoplasms	Associate	26613407, 29976159, 32311005
Neoplasms	Stimulate	30068336
Prostatic Neoplasms	Associate	36787737
Pruritus Ani	Associate	28617547
Recurrence	Associate	28617547
Thyroid Neoplasms	Associate	26431489

MASTL (microtubule associated serine/threonine kinase like)