Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	84902
Gene name Gene Name - the full gene name approved by the HGNC.	Centrosomal protein 89
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CEP89
Synonyms (NCBI Gene) Gene synonyms aliases	CCDC123, CEP123
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.11

Show/Hide all(144)

miRTarBase ID	miRNA	Experiments	Reference
MIRT626494	hsa-miR-7705	HITS-CLIP	23824327
MIRT626491	hsa-miR-103b	HITS-CLIP	23824327
MIRT626488	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT637695	hsa-miR-3135b	HITS-CLIP	23824327
MIRT637694	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT637693	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT626487	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT518061	hsa-miR-3652	HITS-CLIP	23824327
MIRT518060	hsa-miR-4430	HITS-CLIP	23824327
MIRT637692	hsa-miR-656-5p	HITS-CLIP	23824327
MIRT626486	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT626484	hsa-miR-5698	HITS-CLIP	23824327
MIRT626494	hsa-miR-7705	HITS-CLIP	23824327
MIRT637696	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT626492	hsa-miR-5693	HITS-CLIP	23824327
MIRT626491	hsa-miR-103b	HITS-CLIP	23824327
MIRT626488	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT637695	hsa-miR-3135b	HITS-CLIP	23824327
MIRT637694	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT637693	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT626487	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT518061	hsa-miR-3652	HITS-CLIP	23824327
MIRT518060	hsa-miR-4430	HITS-CLIP	23824327
MIRT637692	hsa-miR-656-5p	HITS-CLIP	23824327
MIRT626486	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT626484	hsa-miR-5698	HITS-CLIP	23824327
MIRT626498	hsa-miR-4418	HITS-CLIP	23824327
MIRT626497	hsa-miR-509-3-5p	HITS-CLIP	23824327
MIRT626496	hsa-miR-509-5p	HITS-CLIP	23824327
MIRT626495	hsa-miR-6854-5p	HITS-CLIP	23824327
MIRT626494	hsa-miR-7705	HITS-CLIP	23824327
MIRT626493	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT626492	hsa-miR-5693	HITS-CLIP	23824327
MIRT626491	hsa-miR-103b	HITS-CLIP	23824327
MIRT626490	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT626489	hsa-miR-1184	HITS-CLIP	23824327
MIRT626488	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT626487	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT626486	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT626485	hsa-miR-7156-3p	HITS-CLIP	23824327
MIRT626484	hsa-miR-5698	HITS-CLIP	23824327
MIRT540580	hsa-miR-1245a	PAR-CLIP	21572407
MIRT540579	hsa-miR-8079	PAR-CLIP	21572407
MIRT540578	hsa-miR-4714-3p	PAR-CLIP	21572407
MIRT540577	hsa-miR-6513-3p	PAR-CLIP	21572407
MIRT540576	hsa-miR-3155a	PAR-CLIP	21572407
MIRT540575	hsa-miR-3155b	PAR-CLIP	21572407
MIRT540574	hsa-miR-484	PAR-CLIP	21572407
MIRT540573	hsa-miR-1224-3p	PAR-CLIP	21572407
MIRT540572	hsa-miR-6840-3p	PAR-CLIP	21572407
MIRT540571	hsa-miR-1915-3p	PAR-CLIP	21572407
MIRT540570	hsa-miR-6764-5p	PAR-CLIP	21572407
MIRT540569	hsa-miR-4726-3p	PAR-CLIP	21572407
MIRT540568	hsa-miR-532-3p	PAR-CLIP	21572407
MIRT540567	hsa-miR-1260a	PAR-CLIP	21572407
MIRT540566	hsa-miR-1260b	PAR-CLIP	21572407
MIRT540565	hsa-miR-6749-3p	PAR-CLIP	21572407
MIRT518068	hsa-miR-4700-3p	PAR-CLIP	23446348
MIRT518069	hsa-miR-7153-3p	PAR-CLIP	23446348
MIRT518067	hsa-miR-4433b-3p	PAR-CLIP	23446348
MIRT518066	hsa-miR-889-5p	PAR-CLIP	23446348
MIRT518065	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT518064	hsa-miR-4433a-3p	PAR-CLIP	23446348
MIRT518063	hsa-miR-3176	PAR-CLIP	23446348
MIRT518062	hsa-miR-3922-3p	PAR-CLIP	23446348
MIRT518061	hsa-miR-3652	PAR-CLIP	23446348
MIRT518060	hsa-miR-4430	PAR-CLIP	23446348
MIRT518059	hsa-miR-5095	PAR-CLIP	23446348
MIRT518058	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT518057	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT518056	hsa-miR-6842-3p	PAR-CLIP	23446348
MIRT518055	hsa-miR-193a-3p	PAR-CLIP	23446348
MIRT626494	hsa-miR-7705	HITS-CLIP	23824327
MIRT626491	hsa-miR-103b	HITS-CLIP	23824327
MIRT626488	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT637695	hsa-miR-3135b	HITS-CLIP	23824327
MIRT637694	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT637693	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT626487	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT518061	hsa-miR-3652	HITS-CLIP	23824327
MIRT518060	hsa-miR-4430	HITS-CLIP	23824327
MIRT637692	hsa-miR-656-5p	HITS-CLIP	23824327
MIRT626486	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT626484	hsa-miR-5698	HITS-CLIP	23824327
MIRT626494	hsa-miR-7705	HITS-CLIP	23824327
MIRT637696	hsa-miR-6765-3p	HITS-CLIP	23824327
MIRT626492	hsa-miR-5693	HITS-CLIP	23824327
MIRT626491	hsa-miR-103b	HITS-CLIP	23824327
MIRT626488	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT637695	hsa-miR-3135b	HITS-CLIP	23824327
MIRT637694	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT637693	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT626487	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT518061	hsa-miR-3652	HITS-CLIP	23824327
MIRT518060	hsa-miR-4430	HITS-CLIP	23824327
MIRT637692	hsa-miR-656-5p	HITS-CLIP	23824327
MIRT626486	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT626484	hsa-miR-5698	HITS-CLIP	23824327
MIRT626498	hsa-miR-4418	HITS-CLIP	23824327
MIRT626497	hsa-miR-509-3-5p	HITS-CLIP	23824327
MIRT626496	hsa-miR-509-5p	HITS-CLIP	23824327
MIRT626495	hsa-miR-6854-5p	HITS-CLIP	23824327
MIRT626494	hsa-miR-7705	HITS-CLIP	23824327
MIRT626493	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT626492	hsa-miR-5693	HITS-CLIP	23824327
MIRT626491	hsa-miR-103b	HITS-CLIP	23824327
MIRT626490	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT626489	hsa-miR-1184	HITS-CLIP	23824327
MIRT626488	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT626487	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT626486	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT626485	hsa-miR-7156-3p	HITS-CLIP	23824327
MIRT626484	hsa-miR-5698	HITS-CLIP	23824327
MIRT540580	hsa-miR-1245a	PAR-CLIP	21572407
MIRT540579	hsa-miR-8079	PAR-CLIP	21572407
MIRT540578	hsa-miR-4714-3p	PAR-CLIP	21572407
MIRT540577	hsa-miR-6513-3p	PAR-CLIP	21572407
MIRT540576	hsa-miR-3155a	PAR-CLIP	21572407
MIRT540575	hsa-miR-3155b	PAR-CLIP	21572407
MIRT540574	hsa-miR-484	PAR-CLIP	21572407
MIRT540573	hsa-miR-1224-3p	PAR-CLIP	21572407
MIRT540572	hsa-miR-6840-3p	PAR-CLIP	21572407
MIRT540571	hsa-miR-1915-3p	PAR-CLIP	21572407
MIRT540570	hsa-miR-6764-5p	PAR-CLIP	21572407
MIRT540569	hsa-miR-4726-3p	PAR-CLIP	21572407
MIRT540568	hsa-miR-532-3p	PAR-CLIP	21572407
MIRT540567	hsa-miR-1260a	PAR-CLIP	21572407
MIRT540566	hsa-miR-1260b	PAR-CLIP	21572407
MIRT540565	hsa-miR-6749-3p	PAR-CLIP	21572407
MIRT518068	hsa-miR-4700-3p	PAR-CLIP	23446348
MIRT518069	hsa-miR-7153-3p	PAR-CLIP	23446348
MIRT518067	hsa-miR-4433b-3p	PAR-CLIP	23446348
MIRT518066	hsa-miR-889-5p	PAR-CLIP	23446348
MIRT518065	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT518064	hsa-miR-4433a-3p	PAR-CLIP	23446348
MIRT518063	hsa-miR-3176	PAR-CLIP	23446348
MIRT518062	hsa-miR-3922-3p	PAR-CLIP	23446348
MIRT518061	hsa-miR-3652	PAR-CLIP	23446348
MIRT518060	hsa-miR-4430	PAR-CLIP	23446348
MIRT518059	hsa-miR-5095	PAR-CLIP	23446348
MIRT518058	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT518057	hsa-miR-6807-5p	PAR-CLIP	23446348
MIRT518056	hsa-miR-6842-3p	PAR-CLIP	23446348
MIRT518055	hsa-miR-193a-3p	PAR-CLIP	23446348

Show/Hide all(17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000922	Component	Spindle pole	IDA	21399614
GO:0005515	Function	Protein binding	IPI	23789104
GO:0005758	Component	Mitochondrial intermembrane space	IEA
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005814	Component	Centriole	IDA	23348840
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA
GO:0007005	Process	Mitochondrion organization	IEA
GO:0007268	Process	Chemical synaptic transmission	IEA
GO:0031514	Component	Motile cilium	IEA
GO:0045202	Component	Synapse	IEA
GO:0060271	Process	Cilium assembly	IMP	23348840
GO:0097539	Component	Ciliary transition fiber	IDA	23348840, 23789104
GO:0097711	Process	Ciliary basal body-plasma membrane docking	TAS
GO:0097730	Component	Non-motile cilium	IDA	23789104
GO:1905515	Process	Non-motile cilium assembly	IMP	23789104

MIM	HGNC	e!Ensembl
615470	25907	ENSG00000121289

Protein

UniProt ID

Q96ST8

Protein name

Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123)

Protein function

Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity.

Family and domains

Sequence

MLLGFRRGRRSHFKHIIHGLLPAASVAPKAAVPRTPPPRSPNPSPERPRSALAAAILATT
LTGRTVAIPQPRQRSRSESDVSSVEQDSFIEPYATTSQLRPRPNWQSEMGRRSSLPSFET
LDYGDEEDIETQLSSSGKELGDVSAREDRGGHSDDLYAVPHRNQVPLLHEVNSEDDENIS
HQDGFPGSPPAPQRTQQKDGKHPVLNLKDEKPPLCEKPPPSPDITGRARQRYTEITREKF
EALKEENMDLNNMNQSLTLELNTMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEVAAPE
LLYLRKQAQELVDENDGLKMTVHRLNVELSRYQTKFRHLSKEESLNIEGLPSKGPIPPWL
LDIKYLSPLLLAYEDMMKEKDELNATLKEEMRMFRMRVQEVVKENEELHQELNKSSAVTS
EEWRQLQTQAKLVLEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLMLLEAKTHGQE
KELAENREQLEILRAKCQELKTHSDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELME
KLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMS
AHQYLANLVGLAENITQERDSLMCLAKCLESEKDGVLNKVIKSNIRLGKLEEKVKGYKKQ
AALKLGDISHRLLEQQEDFAGKTAQYRQEMRHLHQVLKDKQEVLDQALQQNREMEGELEV
IWESTFRENRRIRELLQDTLTRTGVQDNPRALVAPSLNGVSQADLLDGCDVCSYDLKSHA
PTC

Sequence length

783

Interactions

View interactions

	Reactome
			Anchoring of the basal body to the plasma membrane

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	21452313

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Mental retardation	intellectual disability	GenCC
Kidney Disease	Kidney Disease	GWAS

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Renal Insufficiency Chronic	Associate	20383145

CEP89 (centrosomal protein 89)