Gene Gene information from NCBI Gene database.
Entrez ID 84890
Gene name 2-aminoethanethiol dioxygenase
Gene symbol ADO
Synonyms (NCBI Gene)
C10orf22
Chromosome 10
Chromosome location 10q21.3
Summary Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine
miRNA miRNA information provided by mirtarbase database.
392
miRTarBase ID miRNA Experiments Reference
MIRT020373 hsa-miR-29c-3p Sequencing 20371350
MIRT022087 hsa-miR-128-3p Sequencing 20371350
MIRT023381 hsa-miR-122-5p Microarray 17612493
MIRT025531 hsa-miR-34a-5p Sequencing 20371350
MIRT025852 hsa-miR-7-5p Microarray 19073608
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
GO ID Ontology Definition Evidence Reference
GO:0005506 Function Iron ion binding IDA 34508780
GO:0005506 Function Iron ion binding IEA
GO:0005506 Function Iron ion binding ISS
GO:0005515 Function Protein binding IPI 28514442, 32296183, 33961781
GO:0005739 Component Mitochondrion HTP 34800366
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611392 23506 ENSG00000181915
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96SZ5
Protein name 2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase)
Protein function Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate (PubMed:1758181
PDB 7REI , 8U9J , 8UAN
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07847 PCO_ADO 57 268 PCO_ADO Family
Sequence
Sequence length 270
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Taurine and hypotaurine metabolism
Metabolic pathways
  Degradation of cysteine and homocysteine