ADO (2-aminoethanethiol dioxygenase)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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84890 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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2-aminoethanethiol dioxygenase |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ADO |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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C10orf22 |
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Chromosome
Chromosome number
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10 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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10q21.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q96SZ5 | ||||||||||
| Protein name | 2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase) | ||||||||||
| Protein function | Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate (PubMed:1758181 | ||||||||||
| PDB | 7REI , 8U9J , 8UAN | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 270 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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