Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	84885
Gene name	ZDHHC palmitoyltransferase 12
Gene symbol	ZDHHC12
Synonyms (NCBI Gene)	DHHC-12ZNF400
Chromosome	9
Chromosome location	9q34.11

128

Show/Hide all (128)

miRTarBase ID	miRNA	Experiments
MIRT1507690	hsa-miR-1908	CLIP-seq
MIRT1507691	hsa-miR-2861	CLIP-seq
MIRT1507692	hsa-miR-342-5p	CLIP-seq
MIRT1507693	hsa-miR-3940-3p	CLIP-seq
MIRT1507694	hsa-miR-4486	CLIP-seq
MIRT1507695	hsa-miR-4492	CLIP-seq
MIRT1507696	hsa-miR-4498	CLIP-seq
MIRT1507697	hsa-miR-4505	CLIP-seq
MIRT1507698	hsa-miR-4508	CLIP-seq
MIRT1507699	hsa-miR-4527	CLIP-seq
MIRT1507700	hsa-miR-4532	CLIP-seq
MIRT1507701	hsa-miR-4651	CLIP-seq
MIRT1507702	hsa-miR-4664-5p	CLIP-seq
MIRT1507703	hsa-miR-4731-5p	CLIP-seq
MIRT1507704	hsa-miR-513a-3p	CLIP-seq
MIRT1507705	hsa-miR-548n	CLIP-seq
MIRT1507706	hsa-miR-548t	CLIP-seq
MIRT1507707	hsa-miR-595	CLIP-seq
MIRT1507708	hsa-miR-608	CLIP-seq
MIRT1507709	hsa-miR-635	CLIP-seq
MIRT1507710	hsa-miR-648	CLIP-seq
MIRT1507711	hsa-miR-661	CLIP-seq
MIRT1507712	hsa-miR-663	CLIP-seq
MIRT1507713	hsa-miR-744	CLIP-seq
MIRT1507714	hsa-miR-762	CLIP-seq
MIRT1507715	hsa-miR-885-3p	CLIP-seq
MIRT2152911	hsa-miR-1207-3p	CLIP-seq
MIRT1507690	hsa-miR-1908	CLIP-seq
MIRT1507691	hsa-miR-2861	CLIP-seq
MIRT2152912	hsa-miR-3144-5p	CLIP-seq
MIRT2152913	hsa-miR-3191	CLIP-seq
MIRT2152914	hsa-miR-3192	CLIP-seq
MIRT2152915	hsa-miR-339-3p	CLIP-seq
MIRT1507692	hsa-miR-342-5p	CLIP-seq
MIRT2152916	hsa-miR-3654	CLIP-seq
MIRT2152917	hsa-miR-3689a-3p	CLIP-seq
MIRT2152918	hsa-miR-3689c	CLIP-seq
MIRT2152919	hsa-miR-378	CLIP-seq
MIRT2152920	hsa-miR-378b	CLIP-seq
MIRT2152921	hsa-miR-378c	CLIP-seq
MIRT2152922	hsa-miR-378d	CLIP-seq
MIRT2152923	hsa-miR-378e	CLIP-seq
MIRT2152924	hsa-miR-378f	CLIP-seq
MIRT2152925	hsa-miR-378h	CLIP-seq
MIRT2152926	hsa-miR-378i	CLIP-seq
MIRT2152927	hsa-miR-3921	CLIP-seq
MIRT1507693	hsa-miR-3940-3p	CLIP-seq
MIRT2152928	hsa-miR-422a	CLIP-seq
MIRT2152929	hsa-miR-4303	CLIP-seq
MIRT2152930	hsa-miR-4314	CLIP-seq
MIRT1507694	hsa-miR-4486	CLIP-seq
MIRT1507695	hsa-miR-4492	CLIP-seq
MIRT1507696	hsa-miR-4498	CLIP-seq
MIRT1507697	hsa-miR-4505	CLIP-seq
MIRT1507698	hsa-miR-4508	CLIP-seq
MIRT1507699	hsa-miR-4527	CLIP-seq
MIRT1507700	hsa-miR-4532	CLIP-seq
MIRT2152931	hsa-miR-4646-5p	CLIP-seq
MIRT1507701	hsa-miR-4651	CLIP-seq
MIRT2152932	hsa-miR-4652-5p	CLIP-seq
MIRT2152933	hsa-miR-4653-5p	CLIP-seq
MIRT1507702	hsa-miR-4664-5p	CLIP-seq
MIRT2152934	hsa-miR-4667-5p	CLIP-seq
MIRT2152935	hsa-miR-4700-5p	CLIP-seq
MIRT2152936	hsa-miR-4728-5p	CLIP-seq
MIRT1507703	hsa-miR-4731-5p	CLIP-seq
MIRT1507704	hsa-miR-513a-3p	CLIP-seq
MIRT1507707	hsa-miR-595	CLIP-seq
MIRT1507708	hsa-miR-608	CLIP-seq
MIRT2152937	hsa-miR-615-5p	CLIP-seq
MIRT1507709	hsa-miR-635	CLIP-seq
MIRT2152938	hsa-miR-637	CLIP-seq
MIRT1507710	hsa-miR-648	CLIP-seq
MIRT1507711	hsa-miR-661	CLIP-seq
MIRT1507712	hsa-miR-663	CLIP-seq
MIRT1507713	hsa-miR-744	CLIP-seq
MIRT1507714	hsa-miR-762	CLIP-seq
MIRT1507715	hsa-miR-885-3p	CLIP-seq
MIRT2373239	hsa-miR-1207-5p	CLIP-seq
MIRT2373240	hsa-miR-127-5p	CLIP-seq
MIRT1507690	hsa-miR-1908	CLIP-seq
MIRT1507691	hsa-miR-2861	CLIP-seq
MIRT2373241	hsa-miR-3120-5p	CLIP-seq
MIRT2152914	hsa-miR-3192	CLIP-seq
MIRT1507692	hsa-miR-342-5p	CLIP-seq
MIRT2373242	hsa-miR-345	CLIP-seq
MIRT2373243	hsa-miR-3616-3p	CLIP-seq
MIRT2152917	hsa-miR-3689a-3p	CLIP-seq
MIRT2152918	hsa-miR-3689c	CLIP-seq
MIRT2373244	hsa-miR-3714	CLIP-seq
MIRT1507693	hsa-miR-3940-3p	CLIP-seq
MIRT2152930	hsa-miR-4314	CLIP-seq
MIRT1507694	hsa-miR-4486	CLIP-seq
MIRT1507695	hsa-miR-4492	CLIP-seq
MIRT1507696	hsa-miR-4498	CLIP-seq
MIRT1507697	hsa-miR-4505	CLIP-seq
MIRT1507698	hsa-miR-4508	CLIP-seq
MIRT1507699	hsa-miR-4527	CLIP-seq
MIRT1507700	hsa-miR-4532	CLIP-seq
MIRT2373245	hsa-miR-4635	CLIP-seq
MIRT2152931	hsa-miR-4646-5p	CLIP-seq
MIRT1507701	hsa-miR-4651	CLIP-seq
MIRT1507702	hsa-miR-4664-5p	CLIP-seq
MIRT2152934	hsa-miR-4667-5p	CLIP-seq
MIRT2152935	hsa-miR-4700-5p	CLIP-seq
MIRT2373246	hsa-miR-4721	CLIP-seq
MIRT2152936	hsa-miR-4728-5p	CLIP-seq
MIRT1507703	hsa-miR-4731-5p	CLIP-seq
MIRT2373247	hsa-miR-4763-3p	CLIP-seq
MIRT1507704	hsa-miR-513a-3p	CLIP-seq
MIRT1507705	hsa-miR-548n	CLIP-seq
MIRT1507706	hsa-miR-548t	CLIP-seq
MIRT1507707	hsa-miR-595	CLIP-seq
MIRT1507708	hsa-miR-608	CLIP-seq
MIRT2152937	hsa-miR-615-5p	CLIP-seq
MIRT1507709	hsa-miR-635	CLIP-seq
MIRT2152938	hsa-miR-637	CLIP-seq
MIRT1507710	hsa-miR-648	CLIP-seq
MIRT1507711	hsa-miR-661	CLIP-seq
MIRT1507712	hsa-miR-663	CLIP-seq
MIRT1507713	hsa-miR-744	CLIP-seq
MIRT1507714	hsa-miR-762	CLIP-seq
MIRT1507715	hsa-miR-885-3p	CLIP-seq
MIRT2373248	hsa-miR-940	CLIP-seq
MIRT2152915	hsa-miR-339-3p	CLIP-seq
MIRT2152927	hsa-miR-3921	CLIP-seq
MIRT2152929	hsa-miR-4303	CLIP-seq
MIRT2152933	hsa-miR-4653-5p	CLIP-seq

Show/Hide all (34)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0000139	Component	Golgi membrane	ISS
GO:0005515	Function	Protein binding	IPI	39225180
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA	16647879
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IDA	16647879
GO:0005794	Component	Golgi apparatus	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0006612	Process	Protein targeting to membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0016409	Function	Palmitoyltransferase activity	IDA	23034182
GO:0016409	Function	Palmitoyltransferase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016746	Function	Acyltransferase activity	IEA
GO:0018230	Process	Peptidyl-L-cysteine S-palmitoylation	ISS
GO:0019706	Function	Protein-cysteine S-palmitoyltransferase activity	IBA
GO:0019706	Function	Protein-cysteine S-palmitoyltransferase activity	IDA	25025157, 36586411
GO:0019706	Function	Protein-cysteine S-palmitoyltransferase activity	IEA
GO:0030163	Process	Protein catabolic process	IDA	36586411
GO:0032230	Process	Positive regulation of synaptic transmission, GABAergic	IEA
GO:0032230	Process	Positive regulation of synaptic transmission, GABAergic	ISS
GO:0043197	Component	Dendritic spine	IDA	25025157
GO:0051932	Process	Synaptic transmission, GABAergic	IDA	14993607, 23909897
GO:0051932	Process	Synaptic transmission, GABAergic	ISS
GO:0061684	Process	Chaperone-mediated autophagy	IDA	36586411
GO:0061740	Process	Protein targeting to lysosome involved in chaperone-mediated autophagy	IDA	36586411
GO:0097112	Process	Gamma-aminobutyric acid receptor clustering	IMP	25025157
GO:0097116	Process	Gephyrin clustering involved in postsynaptic density assembly	IDA	25025157
GO:0097116	Process	Gephyrin clustering involved in postsynaptic density assembly	IEA
GO:0097116	Process	Gephyrin clustering involved in postsynaptic density assembly	ISS
GO:1900226	Process	Negative regulation of NLRP3 inflammasome complex assembly	IDA	36586411

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q96GR4

Protein name

Palmitoyltransferase ZDHHC12 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 12) (DHHC-12) (Zinc finger DHHC domain-containing protein 12) (Zinc finger protein 400)

Protein function

Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (PubMed:36586411). Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyr

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01529	DHHC	93 → 218	DHHC palmitoyltransferase	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16647879}.

Sequence

MAPWALLSPGVLVRTGHTVLTWGITLVLFLHDTELRQWEEQGELLLPLTFLLLVLGSLLL
YLAVSLMDPGYVNVQPQPQEELKEEQTAMVPPAIPLRRCRYCLVLQPLRARHCRECRRCV
RRYDHHCPWMENCVGERNHPLFVVYLALQLVVLLWGLYLAWSGLRFFQPWGQWLRSSGLL
FATFLLLSLFSLVASLLLVSHLYLVASNTTTWEFISSHRIAYLRQRPSNPFDRGLTRNLA
HFFCGWPSGSWETLWAEEEEEGSSPAV

Sequence length

267

Interactions

View interactions

ZDHHC12 (zDHHC palmitoyltransferase 12)