Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84830
Gene name Gene Name - the full gene name approved by the HGNC.
Androgen dependent TFPI regulating protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ADTRP
Synonyms (NCBI Gene) Gene synonyms aliases
AIG1L, C6orf105, dJ413H6.1
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p24.1
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001934 Process Positive regulation of protein phosphorylation IMP 28341552
GO:0002042 Process Cell migration involved in sprouting angiogenesis IMP 28341552
GO:0002686 Process Negative regulation of leukocyte migration IMP 28341552
GO:0003332 Process Negative regulation of extracellular matrix constituent secretion IMP 28341552
GO:0005515 Function Protein binding IPI 32296183
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
614348 21214 ENSG00000111863
Protein
UniProt ID Q96IZ2
Protein name Androgen-dependent TFPI-regulating protein (Fatty acid esters of hydroxy fatty acids hydrolase ADTRP) (FAHFA hydrolase ADTRP) (EC 3.1.-.-)
Protein function Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids (PubMed:27018888). Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids (PubMed:27018888).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04750 Far-17a_AIG1 5 216 FAR-17a/AIG1-like protein Family
Tissue specificity TISSUE SPECIFICITY: Expressed in cultured endothelial cells and in placenta. {ECO:0000269|PubMed:21868574}.
Sequence
Sequence length 230
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537 21378986
Unknown
Disease term Disease name Evidence References Source
Coronary heart disease Coronary heart disease 21378986 ClinVar
Neuroticism Neuroticism GWAS
Colorectal Cancer Colorectal Cancer In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1. GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Asymptomatic Diseases Associate 25928384
Atherosclerosis Associate 25595457, 28341552, 28645652
Cardiovascular Diseases Associate 28645652
Cerebral Arterial Diseases Associate 27235449
Coronary Artery Disease Associate 22952750, 24573017, 25595457, 25928384, 26375920, 27235449, 28341552, 28645652, 32790694, 36435092
Disease Associate 36435092
Hyperuricemia Associate 25928384
Leiomyoma Associate 28715450
Obesity Inhibit 25595457