Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84790
Gene name Gene Name - the full gene name approved by the HGNC.
Tubulin alpha 1c
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TUBA1C
Synonyms (NCBI Gene) Gene synonyms aliases
OZEMA24, TUBA6, bcm948
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q13.12
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT031663 hsa-miR-16-5p Proteomics 18668040
MIRT052239 hsa-let-7b-5p CLASH 23622248
MIRT049110 hsa-miR-92a-3p CLASH 23622248
MIRT046865 hsa-miR-221-3p CLASH 23622248
MIRT043045 hsa-miR-324-5p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000226 Process Microtubule cytoskeleton organization IBA 21873635
GO:0000278 Process Mitotic cell cycle IBA 21873635
GO:0003924 Function GTPase activity IEA
GO:0005198 Function Structural molecule activity TAS 12090300
GO:0005200 Function Structural constituent of cytoskeleton IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
621161 20768 ENSG00000167553
Protein
UniProt ID Q9BQE3
Protein name Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Protein function Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule en
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00091 Tubulin 3 214 Tubulin/FtsZ family, GTPase domain Domain
PF03953 Tubulin_C 263 393 Tubulin C-terminal domain Domain
Sequence
Sequence length 449
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Phagosome
Apoptosis
Tight junction
Gap junction
Motor proteins
Alzheimer disease
Parkinson disease
Amyotrophic lateral sclerosis
Huntington disease
Prion disease
Pathways of neurodegeneration - multiple diseases
Pathogenic Escherichia coli infection
Salmonella infection
  Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Recruitment of NuMA to mitotic centrosomes
Recycling pathway of L1
Hedgehog 'off' state
Cilium Assembly
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast carcinoma Breast Carcinoma rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451
View all (71 more)
27197191
Colonic neoplasms Malignant tumor of colon rs267607789, rs774277300, rs781222233, rs1060502734, rs1060503333, rs1339238483 27197191
Colorectal cancer Colorectal Carcinoma, Adenocarcinoma of large intestine rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800
View all (467 more)
27197191
Colorectal neoplasms Colorectal Neoplasms, Malignant neoplasm of large intestine rs28929483, rs63751108, rs28929484, rs63749831, rs63750047, rs63751207, rs63749811, rs1553350126, rs63750875, rs63750955, rs587776706, rs63750871, rs587776715, rs63751466, rs63750049
View all (1682 more)
27197191
Unknown
Disease term Disease name Evidence References Source
Coronary syndrome Acute Coronary Syndrome 21751358 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Behcet Syndrome Stimulate 29902281
Breast Neoplasms Associate 38032902
Carcinoma Renal Cell Associate 39301023
Cardiomyopathy Restrictive Associate 36174041
Colitis Ulcerative Associate 32322884
Glioblastoma Associate 35513790
Glioma Associate 38454689
Kidney Neoplasms Associate 39301023
Neoplasm Metastasis Stimulate 38032902
Neoplasms Associate 35513790, 36466547, 37528357, 39301023