MGARP (mitochondria localized glutamic acid rich protein)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84709
Gene name Gene Name - the full gene name approved by the HGNC.
Mitochondria localized glutamic acid rich protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MGARP
Synonyms (NCBI Gene) Gene synonyms aliases
C4orf49, CESP-1, HUMMR, OSAP
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q31.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(34)
miRTarBase ID miRNA Experiments Reference
MIRT527383 hsa-miR-548ac PAR-CLIP 22012620
MIRT527382 hsa-miR-548bb-3p PAR-CLIP 22012620
MIRT527381 hsa-miR-548d-3p PAR-CLIP 22012620
MIRT527380 hsa-miR-548h-3p PAR-CLIP 22012620
MIRT527379 hsa-miR-548z PAR-CLIP 22012620
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(13)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 19528298, 32814053
GO:0005739 Component Mitochondrion IDA 16565373, 21447634
GO:0006626 Process Protein targeting to mitochondrion ISS
GO:0008089 Process Anterograde axonal transport ISS
GO:0008090 Process Retrograde axonal transport ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
619684 29969 ENSG00000137463
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q8TDB4
Protein name Protein MGARP (Corneal endothelium-specific protein 1) (CESP-1) (Hypoxia up-regulated mitochondrial movement regulator protein) (Mitochondria-localized glutamic acid-rich protein) (Ovary-specific acidic protein)
Protein function Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the c
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14962 AIF-MLS 1 → 191 Mitochondria Localisation Sequence Family
Tissue specificity TISSUE SPECIFICITY: Expressed in the brain, adrenal gland and corneal endothelium (CE). Expressed in steroid-producing cells of the ovary and testis (at protein level). Expressed in steroid-producing cells of the ovary and testis. Weakly expressed in plac
Sequence
Sequence length 240
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Rheumatoid arthritis Rheumatoid Arthritis rs587776843 17568789