Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	847
Gene name Gene Name - the full gene name approved by the HGNC.	Catalase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CAT
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11p13
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide t

Show/Hide all(2)

SNP ID	Visualize variation	Clinical significance	Consequence
rs761650208	G>A	Pathogenic	Intron variant
rs1590302115	T>-	Pathogenic	Coding sequence variant, frameshift variant

Show/Hide all(123)

miRTarBase ID	miRNA	Experiments	Reference
MIRT007067	hsa-miR-30b-5p	Luciferase reporter assay, qRT-PCR, Western blot	22880027
MIRT007067	hsa-miR-30b-5p	Luciferase reporter assay, qRT-PCR, Western blot	22880027
MIRT020866	hsa-miR-155-5p	Proteomics	18668040
MIRT028614	hsa-miR-30a-5p	Proteomics	18668040
MIRT047237	hsa-miR-181b-5p	CLASH	23622248
MIRT864422	hsa-miR-1179	CLIP-seq
MIRT864423	hsa-miR-1250	CLIP-seq
MIRT864424	hsa-miR-1267	CLIP-seq
MIRT864425	hsa-miR-146a	CLIP-seq
MIRT864426	hsa-miR-146b-5p	CLIP-seq
MIRT864427	hsa-miR-148a	CLIP-seq
MIRT864428	hsa-miR-148b	CLIP-seq
MIRT864429	hsa-miR-152	CLIP-seq
MIRT864430	hsa-miR-190	CLIP-seq
MIRT864431	hsa-miR-190b	CLIP-seq
MIRT864432	hsa-miR-2110	CLIP-seq
MIRT864433	hsa-miR-30a	CLIP-seq
MIRT864434	hsa-miR-30b	CLIP-seq
MIRT864435	hsa-miR-30c	CLIP-seq
MIRT864436	hsa-miR-30d	CLIP-seq
MIRT864437	hsa-miR-30e	CLIP-seq
MIRT864438	hsa-miR-3143	CLIP-seq
MIRT864439	hsa-miR-337-3p	CLIP-seq
MIRT864440	hsa-miR-3611	CLIP-seq
MIRT864441	hsa-miR-361-5p	CLIP-seq
MIRT864442	hsa-miR-3646	CLIP-seq
MIRT864443	hsa-miR-3662	CLIP-seq
MIRT864444	hsa-miR-3685	CLIP-seq
MIRT864445	hsa-miR-3689a-5p	CLIP-seq
MIRT864446	hsa-miR-3689b	CLIP-seq
MIRT864447	hsa-miR-3689e	CLIP-seq
MIRT864448	hsa-miR-3689f	CLIP-seq
MIRT864449	hsa-miR-369-3p	CLIP-seq
MIRT864450	hsa-miR-374a	CLIP-seq
MIRT864451	hsa-miR-374b	CLIP-seq
MIRT864452	hsa-miR-380	CLIP-seq
MIRT864453	hsa-miR-384	CLIP-seq
MIRT864454	hsa-miR-3907	CLIP-seq
MIRT864455	hsa-miR-4271	CLIP-seq
MIRT864456	hsa-miR-4275	CLIP-seq
MIRT864457	hsa-miR-4282	CLIP-seq
MIRT864458	hsa-miR-4297	CLIP-seq
MIRT864459	hsa-miR-4303	CLIP-seq
MIRT864460	hsa-miR-4495	CLIP-seq
MIRT864461	hsa-miR-4667-5p	CLIP-seq
MIRT864462	hsa-miR-4680-3p	CLIP-seq
MIRT864463	hsa-miR-4682	CLIP-seq
MIRT864464	hsa-miR-4700-5p	CLIP-seq
MIRT864465	hsa-miR-4712-3p	CLIP-seq
MIRT864466	hsa-miR-4717-5p	CLIP-seq
MIRT864467	hsa-miR-4725-3p	CLIP-seq
MIRT864468	hsa-miR-4762-3p	CLIP-seq
MIRT864469	hsa-miR-4795-3p	CLIP-seq
MIRT864470	hsa-miR-512-3p	CLIP-seq
MIRT864471	hsa-miR-513a-3p	CLIP-seq
MIRT864472	hsa-miR-543	CLIP-seq
MIRT864473	hsa-miR-548c-3p	CLIP-seq
MIRT864474	hsa-miR-576-5p	CLIP-seq
MIRT864475	hsa-miR-589	CLIP-seq
MIRT864476	hsa-miR-873	CLIP-seq
MIRT864477	hsa-miR-889	CLIP-seq
MIRT864478	hsa-miR-944	CLIP-seq
MIRT1956212	hsa-miR-1825	CLIP-seq
MIRT864430	hsa-miR-190	CLIP-seq
MIRT864431	hsa-miR-190b	CLIP-seq
MIRT1956213	hsa-miR-199a-5p	CLIP-seq
MIRT1956214	hsa-miR-199b-5p	CLIP-seq
MIRT864433	hsa-miR-30a	CLIP-seq
MIRT864434	hsa-miR-30b	CLIP-seq
MIRT864435	hsa-miR-30c	CLIP-seq
MIRT864436	hsa-miR-30d	CLIP-seq
MIRT864437	hsa-miR-30e	CLIP-seq
MIRT864438	hsa-miR-3143	CLIP-seq
MIRT864445	hsa-miR-3689a-5p	CLIP-seq
MIRT864446	hsa-miR-3689b	CLIP-seq
MIRT864447	hsa-miR-3689e	CLIP-seq
MIRT864448	hsa-miR-3689f	CLIP-seq
MIRT864452	hsa-miR-380	CLIP-seq
MIRT1956215	hsa-miR-3925-3p	CLIP-seq
MIRT864460	hsa-miR-4495	CLIP-seq
MIRT1956216	hsa-miR-4718	CLIP-seq
MIRT1956217	hsa-miR-4742-3p	CLIP-seq
MIRT864468	hsa-miR-4762-3p	CLIP-seq
MIRT1956218	hsa-miR-4764-3p	CLIP-seq
MIRT1956219	hsa-miR-508-5p	CLIP-seq
MIRT864472	hsa-miR-543	CLIP-seq
MIRT2193853	hsa-miR-3117-5p	CLIP-seq
MIRT1956216	hsa-miR-4718	CLIP-seq
MIRT1956217	hsa-miR-4742-3p	CLIP-seq
MIRT864425	hsa-miR-146a	CLIP-seq
MIRT864426	hsa-miR-146b-5p	CLIP-seq
MIRT2193853	hsa-miR-3117-5p	CLIP-seq
MIRT864439	hsa-miR-337-3p	CLIP-seq
MIRT2497103	hsa-miR-3651	CLIP-seq
MIRT864444	hsa-miR-3685	CLIP-seq
MIRT864453	hsa-miR-384	CLIP-seq
MIRT864457	hsa-miR-4282	CLIP-seq
MIRT864459	hsa-miR-4303	CLIP-seq
MIRT864463	hsa-miR-4682	CLIP-seq
MIRT864465	hsa-miR-4712-3p	CLIP-seq
MIRT1956216	hsa-miR-4718	CLIP-seq
MIRT1956217	hsa-miR-4742-3p	CLIP-seq
MIRT864468	hsa-miR-4762-3p	CLIP-seq
MIRT864471	hsa-miR-513a-3p	CLIP-seq
MIRT864473	hsa-miR-548c-3p	CLIP-seq
MIRT864475	hsa-miR-589	CLIP-seq
MIRT864477	hsa-miR-889	CLIP-seq
MIRT864425	hsa-miR-146a	CLIP-seq
MIRT864426	hsa-miR-146b-5p	CLIP-seq
MIRT2193853	hsa-miR-3117-5p	CLIP-seq
MIRT864439	hsa-miR-337-3p	CLIP-seq
MIRT864444	hsa-miR-3685	CLIP-seq
MIRT864453	hsa-miR-384	CLIP-seq
MIRT864457	hsa-miR-4282	CLIP-seq
MIRT864459	hsa-miR-4303	CLIP-seq
MIRT864463	hsa-miR-4682	CLIP-seq
MIRT864465	hsa-miR-4712-3p	CLIP-seq
MIRT1956216	hsa-miR-4718	CLIP-seq
MIRT1956217	hsa-miR-4742-3p	CLIP-seq
MIRT864468	hsa-miR-4762-3p	CLIP-seq
MIRT864471	hsa-miR-513a-3p	CLIP-seq
MIRT864473	hsa-miR-548c-3p	CLIP-seq
MIRT864475	hsa-miR-589	CLIP-seq

Transcription factors

Show/Hide all(6)

Transcription factor	Regulation	Reference
EGR3	Activation	1906159
ETV1	Unknown	19763505
NFE2L2	Activation	22493435
PPARD	Activation	18048767
PPARG	Unknown	20075562
SP1	Unknown	11479230

Show/Hide all(80)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000302	Process	Response to reactive oxygen species	IEA
GO:0000302	Process	Response to reactive oxygen species	IMP	16644728
GO:0001649	Process	Osteoblast differentiation	HDA	16210410
GO:0001657	Process	Ureteric bud development	IEA
GO:0001666	Process	Response to hypoxia	IEA
GO:0001822	Process	Kidney development	IEA
GO:0004046	Function	Aminoacylase activity	IEA
GO:0004096	Function	Catalase activity	IBA
GO:0004096	Function	Catalase activity	IDA	7882369, 16644728, 18312938, 18379038
GO:0004096	Function	Catalase activity	IEA
GO:0004601	Function	Peroxidase activity	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005739	Component	Mitochondrion	IBA
GO:0005777	Component	Peroxisome	IBA
GO:0005777	Component	Peroxisome	IDA	8769411
GO:0005777	Component	Peroxisome	IDA	2895531, 9053548, 18379038, 19479899
GO:0005777	Component	Peroxisome	IEA
GO:0005778	Component	Peroxisomal membrane	IEA
GO:0005778	Component	Peroxisomal membrane	ISS
GO:0005782	Component	Peroxisomal matrix	IEA
GO:0005782	Component	Peroxisomal matrix	TAS
GO:0005829	Component	Cytosol	TAS
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0006641	Process	Triglyceride metabolic process	IEA
GO:0006979	Process	Response to oxidative stress	IEA
GO:0006979	Process	Response to oxidative stress	IEA
GO:0008203	Process	Cholesterol metabolic process	IEA
GO:0009060	Process	Aerobic respiration	IEA
GO:0009410	Process	Response to xenobiotic stimulus	IEA
GO:0009411	Process	Response to UV	IEA
GO:0009636	Process	Response to toxic substance	IEA
GO:0009642	Process	Response to light intensity	IEA
GO:0009650	Process	UV protection	IMP	16644728, 17053817
GO:0010193	Process	Response to ozone	IEA
GO:0010288	Process	Response to lead ion	IEA
GO:0014823	Process	Response to activity	IEA
GO:0014854	Process	Response to inactivity	IEA
GO:0016020	Component	Membrane	HDA	16210410, 19946888
GO:0016209	Function	Antioxidant activity	IDA	10514471
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016684	Function	Oxidoreductase activity, acting on peroxide as acceptor	IEA
GO:0016684	Function	Oxidoreductase activity, acting on peroxide as acceptor	ISS
GO:0019899	Function	Enzyme binding	IPI	16781659
GO:0020027	Process	Hemoglobin metabolic process	IEA
GO:0020037	Function	Heme binding	IBA
GO:0020037	Function	Heme binding	IDA	10656833, 11134921
GO:0020037	Function	Heme binding	IEA
GO:0032355	Process	Response to estradiol	IEA
GO:0032868	Process	Response to insulin	IEA
GO:0032991	Component	Protein-containing complex	IPI	21976670
GO:0033189	Process	Response to vitamin A	IEA
GO:0033197	Process	Response to vitamin E	IEA
GO:0033591	Process	Response to L-ascorbic acid	IEA
GO:0034774	Component	Secretory granule lumen	TAS
GO:0042542	Process	Response to hydrogen peroxide	IBA
GO:0042744	Process	Hydrogen peroxide catabolic process	IBA
GO:0042744	Process	Hydrogen peroxide catabolic process	IDA	18379038
GO:0042744	Process	Hydrogen peroxide catabolic process	IEA
GO:0042744	Process	Hydrogen peroxide catabolic process	IEA
GO:0042802	Function	Identical protein binding	IPI	21976670, 21988832, 29568061
GO:0042803	Function	Protein homodimerization activity	IDA	10656833
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	16644728
GO:0045471	Process	Response to ethanol	IEA
GO:0046686	Process	Response to cadmium ion	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0050661	Function	NADP binding	IDA	10656833
GO:0051781	Process	Positive regulation of cell division	IEA
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA
GO:0055093	Process	Response to hyperoxia	IEA
GO:0061692	Process	Cellular detoxification of hydrogen peroxide	IDA	18379038
GO:0062151	Component	Catalase complex	IPI	10656833
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0070542	Process	Response to fatty acid	IEA
GO:0071363	Process	Cellular response to growth factor stimulus	IEA
GO:0072722	Process	Response to amitrole	IEA
GO:0080184	Process	Response to phenylpropanoid	IEA
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS

MIM	HGNC	e!Ensembl
115500	1516	ENSG00000121691

Protein

UniProt ID

P04040

Protein name

Catalase (EC 1.11.1.6)

Protein function

Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide (PubMed:7882369). Promotes growth of cells including T-cells, B

PDB

1DGB , 1DGF , 1DGG , 1DGH , 1F4J , 1QQW , 7P8W , 7VD9 , 8EL9 , 8HID , 8PVD , 8SGV , 8WZH , 8WZJ , 8WZK , 8WZM

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00199	Catalase	28 → 411	Catalase	Domain
PF06628	Catalase-rel	434 → 497	Catalase-related immune-responsive	Family

Sequence

MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDE
MAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGES
GSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPD
MVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQ
GIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLT
KVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPD
THRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALE
HSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVK
NFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL

Sequence length

527

Interactions

View interactions

	KEGG		Reactome
	Tryptophan metabolism Glyoxylate and dicarboxylate metabolism Metabolic pathways Carbon metabolism FoxO signaling pathway Peroxisome Longevity regulating pathway Longevity regulating pathway - multiple species Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases Chemical carcinogenesis - reactive oxygen species		Detoxification of Reactive Oxygen Species Neutrophil degranulation Peroxisomal protein import

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Acatalasia	Acatalasemia, japanese type, acatalasia	rs761650208, rs1590302115, rs2133181057	N/A

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes	N/A	N/A	GWAS

Show/Hide Text Mining Associations (242)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
AA amyloidosis	Associate	23968537
Acatalasia	Associate	14459853
Acute Kidney Injury	Associate	26787049
Adenocarcinoma	Associate	17409931
Adenocarcinoma of Lung	Associate	32669531, 33299528, 36254009, 8332495
Adenomyosis	Associate	12372460
AIDS Dementia Complex	Associate	19101040
Alzheimer Disease	Associate	18353692, 24817970, 30068908, 31370365, 37772794
Amyotrophic Lateral Sclerosis	Associate	35627142
Amyotrophic lateral sclerosis 1	Associate	8731383
Anemia Sickle Cell	Inhibit	23259718, 30010491, 32170816, 40657454
Aniridia	Associate	3001710
Anthracosis	Associate	12566517
Anti Neutrophil Cytoplasmic Antibody Associated Vasculitis	Associate	9649223
Aortic Aneurysm Abdominal	Associate	22694979
Aortic Aneurysm Thoracic	Associate	32273946, 40436996
Arthritis Juvenile	Associate	26924871
Arthritis Rheumatoid	Associate	19242068
Asbestosis	Associate	19064360, 23984360
Asthma	Associate	16385446, 18048809, 19897513, 23066387, 29504915
Ataxia Telangiectasia	Stimulate	25882094
Barrett Esophagus	Stimulate	15884106
Barrett Esophagus	Associate	24852569
beta Thalassemia	Associate	40004059
Biliary Tract Neoplasms	Associate	31590928
Brain Neoplasms	Associate	18682580
Breast Neoplasms	Associate	19255063, 22551313, 23053794, 23883585, 29535798, 32920119, 35763649, 37774083
Breast Neoplasms	Inhibit	23053794
Carcinogenesis	Associate	21198296, 27876813
Carcinoma Adenoid Cystic	Associate	26847304
Carcinoma Basal Cell	Inhibit	27057281
Carcinoma Hepatocellular	Associate	12716464, 15526362, 18047476, 21985966, 25837767, 3375054, 40179431
Carcinoma Hepatocellular	Inhibit	25361011
Carcinoma Hepatocellular	Stimulate	27227932
Carcinoma Non Small Cell Lung	Associate	22299584
Carcinoma Ovarian Epithelial	Associate	28884887
Carcinoma Renal Cell	Associate	36360294
Cardiomyopathy Dilated	Inhibit	36070401
Cardiovascular Diseases	Associate	36012132
Cataract	Associate	21921984
Cataract	Inhibit	23781296
Cholangiocarcinoma	Associate	34320944
Cholangitis Sclerosing	Associate	29180269, 9649223
Chronic Disease	Associate	38278340
Chronic Limb Threatening Ischemia	Inhibit	25977470
Cognition Disorders	Associate	19101040
Colorectal Neoplasms	Associate	22998821, 33671292, 37313408
Corneal dystrophy Avellino type	Inhibit	19497990
Coronary Artery Disease	Associate	28533333, 30225256
Coronary Artery Disease	Inhibit	36361563
Coronary Disease	Associate	35866783
Coronary Restenosis	Associate	35144391
COVID 19	Associate	32805728, 33492566, 34176789
COVID 19	Stimulate	36493512
Coxa Magna	Associate	18353692
Crohn Disease	Associate	33882797, 36555526
Death	Inhibit	17071589
Death	Associate	26301412, 27993795
Depressive Disorder	Inhibit	19272208
Diabetes Complications	Associate	17264407
Diabetes Gestational	Inhibit	28400911
Diabetes Gestational	Associate	33920886
Diabetes Mellitus	Associate	18353692, 24817970, 36012352
Diabetes Mellitus	Inhibit	32926601
Diabetes Mellitus Type 1	Stimulate	24913117
Diabetes Mellitus Type 1	Associate	27575603
Diabetes Mellitus Type 2	Associate	17264407, 22718504
Diabetes Mellitus Type 2	Inhibit	19019194, 32926601
Diabetic Retinopathy	Associate	29410390
Disease	Inhibit	35841050
Disease	Associate	37879214
Disease	Stimulate	3805316
DNA Virus Infections	Inhibit	28745489, 39973207, 9326648, 9710241
Down Syndrome	Associate	23180588
Drug Hypersensitivity	Associate	29467184
Drug Related Side Effects and Adverse Reactions	Inhibit	10070862, 22564432, 25051199, 25127718, 38197565
Drug Related Side Effects and Adverse Reactions	Associate	18155176, 22016819, 23658745
Edema	Associate	30813952
Endocarditis	Associate	21715584
Endometrial Neoplasms	Associate	12372460
Endometriosis	Associate	12372460, 23416363, 25154023, 36013572
Epilepsies Myoclonic	Associate	29740017
Epilepsy	Associate	22220588
Erysipelas	Associate	28512644
Esophageal Neoplasms	Associate	32398095
Esophagitis	Stimulate	15884106
Essential Hypertension	Associate	15735318, 23701472
Fabry Disease	Associate	15606558
Familial Mediterranean Fever	Associate	31957891
Fatty Liver	Stimulate	26551085
Fatty Liver Alcoholic	Stimulate	26551085
Fluorosis Dental	Associate	35646794
Fragile X Syndrome	Associate	15574425
Friedreich Ataxia	Associate	22016819
Galactosemias	Inhibit	23828587
Gallbladder Neoplasms	Associate	23009611
Genetic Diseases Inborn	Stimulate	20732340
Gingivitis	Inhibit	34204920
Glaucoma Angle Closure	Associate	23961996
Glaucoma Open Angle	Inhibit	28547970
Glaucoma Open Angle	Associate	28547970
Glioblastoma	Associate	24728830, 36035213, 36838582, 38138986
Glioma	Associate	36809279
Glucose Intolerance	Stimulate	27411103
Glucosephosphate Dehydrogenase Deficiency	Associate	2491951
Graves Ophthalmopathy	Associate	22065933
Growth Factors Combined Defect of	Associate	23968537
Hearing Loss	Associate	25484013, 34530960
Hearing Loss Noise Induced	Associate	25484013, 26045794, 29301492, 32176153, 34530960
Hearing Loss Sensorineural	Associate	29740017
Heart Failure	Associate	27647766
Hemolysis	Associate	17605772, 2491951
Hemolytic Uremic Syndrome	Associate	19155520
Hepatitis B Chronic	Associate	25837767, 29214184
Huntington Disease	Associate	11313348
Hyaline Fibromatosis Syndrome	Associate	22220588
Hyperglycemia	Inhibit	24093550
Hypertension	Associate	18353692, 24817970, 25793211, 29504915
Hypertrophy	Associate	30985713
Hypoxia	Associate	19183269
Hypoxia	Stimulate	21477371, 33725925, 40222298
Hypoxia	Inhibit	23812845
Idiopathic Pulmonary Fibrosis	Inhibit	39313791
Infections	Stimulate	12468545
Infections	Associate	21721378
Infertility	Associate	26198800
Infertility Male	Associate	36592993
Inflammation	Associate	30010491, 30176909, 30574618, 34572113, 35627142, 36012132, 39287687
Inflammatory Bowel Diseases	Inhibit	29180269, 33028732
Insulin Resistance	Associate	23641975, 36044932
Intervertebral Disc Degeneration	Associate	36972403
Iron Deficiencies	Associate	19657548
Iron Deficiencies	Inhibit	27647766
Keratoconus	Associate	31576926
Kidney Failure Chronic	Associate	20360867
Lead Poisoning Nervous System	Inhibit	12764543
Leiomyoma	Inhibit	23812845
Leukemia	Associate	27566554, 29467184, 36112236
Leukemia Lymphocytic Chronic B Cell	Associate	29467184, 33115525, 36112236
Leukemia Lymphocytic Chronic B Cell	Inhibit	34001853
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	25115845, 40565143
Leukemia Myelogenous Chronic BCR ABL Positive	Inhibit	25436036, 27566554
Leukoplakia Oral	Associate	32378537
Lichen Planus Oral	Associate	32378537
Liver Cirrhosis	Associate	25837767
Liver Diseases	Associate	25361011, 37759451
Loeys Dietz Syndrome	Associate	32273946
Lumbar Stenosis Familial	Inhibit	30985713
Lung Diseases	Associate	31947722
Lung Neoplasms	Associate	17409931, 31205586, 32648197
Lung Neoplasms	Inhibit	21198296, 26873489
Lupus Erythematosus Systemic	Associate	18606005
Macular Degeneration	Inhibit	27935234
Macular Degeneration	Associate	27935234
Malformations of Cortical Development Group I	Associate	15561702
Malnutrition	Associate	18469277
Melanoma	Associate	11171586, 22970236, 27206673
MELAS Syndrome	Associate	10564713
Mental Disorders	Associate	40725019
MERRF Syndrome	Associate	29740017
MERRF Syndrome	Stimulate	29740017
Metabolic Diseases	Associate	23641975, 35976206
Mitochondrial Diseases	Associate	10564713, 19543395, 21249229, 37726294
Mitral Valve Insufficiency	Associate	21715584
Mucocutaneous Lymph Node Syndrome	Inhibit	36361563
Multiple Chemical Sensitivity	Associate	24812443
Multiple Myeloma	Associate	27902770
Multiple Sclerosis	Associate	35732787
Multiple Sclerosis Relapsing Remitting	Stimulate	23677512
Multiple Sclerosis Relapsing Remitting	Associate	33354282
Muscle Neoplasms	Associate	25532418
Muscular Dystrophy Facioscapulohumeral	Associate	22796148
Necrosis	Associate	22564432, 23883585
Neoplasm Metastasis	Inhibit	21734470, 25674249
Neoplasms	Associate	15115770, 15526362, 21198296, 21734470, 21778829, 22551313, 23456297, 26342455, 27034707, 27077777, 28346693, 28884887, 29421238, 31578342, 36035213, 37253003, 3927997, 8947833 View all (3 more)
Neoplasms	Inhibit	17088916, 25361011, 26873489, 28102840, 28281569
Nephrolithiasis Calcium Oxalate	Inhibit	37191760
Neural Tube Defects	Associate	28397206
Neuroblastoma	Inhibit	22970236
Neurodegenerative Diseases	Associate	23968537
Neuroma Acoustic	Associate	18682580
Neurotoxicity Syndromes	Associate	21249229
Non alcoholic Fatty Liver Disease	Associate	21656912, 29718361
Non alcoholic Fatty Liver Disease	Inhibit	37759451
Nose Diseases	Associate	25584923
Obesity	Inhibit	23641975
Obesity	Associate	23641975, 26123268, 27023799, 28274171, 36044932
Obesity Metabolically Benign	Inhibit	40176047
Osteoarthritis Knee	Inhibit	37879214
Osteosarcoma	Associate	38315381
Otitis Media Suppurative	Associate	23345293
Ovarian Neoplasms	Associate	26301412, 29421935
Pancreatic Neoplasms	Associate	24051964, 28346693, 39942733
Pancreatitis	Associate	35745003
Paratuberculosis	Associate	28631071
Pericarditis	Associate	21715584
Periodontal Diseases	Associate	31470840, 32267380, 34204920
Peroxisomal Disorders	Associate	16103719
Pneumocystis Infections	Inhibit	33128253
Polycystic Ovary Syndrome	Associate	29055959
Polycystic Ovary Syndrome	Inhibit	36593322
Porphyria Acute Intermittent	Associate	27788171
Pre Eclampsia	Associate	33725925
Primary Myelofibrosis	Associate	30570876
Progeria	Associate	32186522
Prostatic Neoplasms	Associate	24711484, 27197287, 27706591, 27993795, 28069826, 29697282
Prostatic Neoplasms	Inhibit	35488328
Prostatic Neoplasms Castration Resistant	Associate	27993795
Psychological Distress	Associate	32184123
Pulmonary Disease Chronic Obstructive	Stimulate	17567676
Pulmonary Disease Chronic Obstructive	Associate	21309732, 29506519, 31564855
Respiration Disorders	Associate	19897513
Respiratory Insufficiency	Associate	19897513
Respiratory Tract Diseases	Associate	19897513
Sarcoma	Inhibit	21871117
Sepsis	Associate	26787049
Skin Neoplasms	Associate	12730222
Sleep Deprivation	Inhibit	19723109
Sleep Deprivation	Associate	26198800
Spinocerebellar Ataxias	Associate	10424816, 15574425, 34635619
Squamous Cell Carcinoma of Head and Neck	Associate	28904321, 29802697
Stomach Diseases	Associate	30574618, 37265823
Stomach Neoplasms	Associate	30114685
Stomatitis	Associate	35319668
Thalassemia	Associate	29365317
Thrombocytopenia	Associate	18606005
Thyroid Neoplasms	Associate	32887540
Triple Negative Breast Neoplasms	Associate	33302699
Uterine Cervical Neoplasms	Associate	22320976, 25307973, 27034707, 8137827
Varicocele	Inhibit	20117772
Varicocele	Associate	36372090
Venous Insufficiency	Associate	23182154
Visceral myopathy familial external ophthalmoplegia	Associate	34070501
Vitamin D Hydroxylation Deficient Rickets Type 1A	Inhibit	3805316
Vitiligo	Associate	11168813, 16528352, 17071589, 18353692, 20613769, 24817970, 39337683
Vitiligo	Inhibit	17943184, 22058000, 9284096
Vitreoretinopathy Proliferative	Associate	37107562
Werner Syndrome	Associate	24799429
Wilms Tumor	Associate	3001710
Wounds and Injuries	Inhibit	37879214
Xeroderma Pigmentosum	Inhibit	11370283
Xeroderma Pigmentosum Complementation Group B	Associate	2995975

CAT (catalase)