Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	84639
Gene name	Interleukin 1 family member 10
Gene symbol	IL1F10
Synonyms (NCBI Gene)	FIL1-thetaFKSG75IL-1HY2IL-38IL1-thetaIL1HY2
Chromosome	2
Chromosome location	2q14.1
Summary	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 fam

Show/Hide all (91)

miRTarBase ID	miRNA	Experiments	Reference
MIRT487502	hsa-miR-4780	PAR-CLIP	20371350
MIRT487501	hsa-miR-6780b-3p	PAR-CLIP	20371350
MIRT487500	hsa-miR-212-5p	PAR-CLIP	20371350
MIRT487499	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT487498	hsa-miR-4784	PAR-CLIP	20371350
MIRT487497	hsa-miR-3119	PAR-CLIP	20371350
MIRT487496	hsa-miR-642b-5p	PAR-CLIP	20371350
MIRT487495	hsa-miR-623	PAR-CLIP	20371350
MIRT487494	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT487493	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT487491	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT487489	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT487502	hsa-miR-4780	PAR-CLIP	20371350
MIRT487501	hsa-miR-6780b-3p	PAR-CLIP	20371350
MIRT487500	hsa-miR-212-5p	PAR-CLIP	20371350
MIRT487499	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT487498	hsa-miR-4784	PAR-CLIP	20371350
MIRT487497	hsa-miR-3119	PAR-CLIP	20371350
MIRT487496	hsa-miR-642b-5p	PAR-CLIP	20371350
MIRT487495	hsa-miR-623	PAR-CLIP	20371350
MIRT487494	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT487493	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT487492	hsa-miR-3692-3p	PAR-CLIP	20371350
MIRT487491	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT487489	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT487502	hsa-miR-4780	PAR-CLIP	23592263
MIRT487501	hsa-miR-6780b-3p	PAR-CLIP	23592263
MIRT487500	hsa-miR-212-5p	PAR-CLIP	23592263
MIRT487499	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT487498	hsa-miR-4784	PAR-CLIP	23592263
MIRT487497	hsa-miR-3119	PAR-CLIP	23592263
MIRT487496	hsa-miR-642b-5p	PAR-CLIP	23592263
MIRT487495	hsa-miR-623	PAR-CLIP	23592263
MIRT487494	hsa-miR-204-5p	PAR-CLIP	23592263
MIRT487493	hsa-miR-211-5p	PAR-CLIP	23592263
MIRT487492	hsa-miR-3692-3p	PAR-CLIP	23592263
MIRT487491	hsa-miR-4755-5p	PAR-CLIP	23592263
MIRT487489	hsa-miR-5006-3p	PAR-CLIP	23592263
MIRT487502	hsa-miR-4780	PAR-CLIP	20371350
MIRT487501	hsa-miR-6780b-3p	PAR-CLIP	20371350
MIRT487500	hsa-miR-212-5p	PAR-CLIP	20371350
MIRT487499	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT487498	hsa-miR-4784	PAR-CLIP	20371350
MIRT487497	hsa-miR-3119	PAR-CLIP	20371350
MIRT487496	hsa-miR-642b-5p	PAR-CLIP	20371350
MIRT487495	hsa-miR-623	PAR-CLIP	20371350
MIRT487494	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT487493	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT487491	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT487489	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT487502	hsa-miR-4780	PAR-CLIP	20371350
MIRT487501	hsa-miR-6780b-3p	PAR-CLIP	20371350
MIRT487500	hsa-miR-212-5p	PAR-CLIP	20371350
MIRT487499	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT487498	hsa-miR-4784	PAR-CLIP	20371350
MIRT487497	hsa-miR-3119	PAR-CLIP	20371350
MIRT487496	hsa-miR-642b-5p	PAR-CLIP	20371350
MIRT487495	hsa-miR-623	PAR-CLIP	20371350
MIRT487494	hsa-miR-204-5p	PAR-CLIP	20371350
MIRT487493	hsa-miR-211-5p	PAR-CLIP	20371350
MIRT487492	hsa-miR-3692-3p	PAR-CLIP	20371350
MIRT487491	hsa-miR-4755-5p	PAR-CLIP	20371350
MIRT487489	hsa-miR-5006-3p	PAR-CLIP	20371350
MIRT487502	hsa-miR-4780	PAR-CLIP	23592263
MIRT487501	hsa-miR-6780b-3p	PAR-CLIP	23592263
MIRT487500	hsa-miR-212-5p	PAR-CLIP	23592263
MIRT487499	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT487498	hsa-miR-4784	PAR-CLIP	23592263
MIRT487497	hsa-miR-3119	PAR-CLIP	23592263
MIRT487496	hsa-miR-642b-5p	PAR-CLIP	23592263
MIRT487495	hsa-miR-623	PAR-CLIP	23592263
MIRT487494	hsa-miR-204-5p	PAR-CLIP	23592263
MIRT487493	hsa-miR-211-5p	PAR-CLIP	23592263
MIRT487492	hsa-miR-3692-3p	PAR-CLIP	23592263
MIRT487491	hsa-miR-4755-5p	PAR-CLIP	23592263
MIRT487489	hsa-miR-5006-3p	PAR-CLIP	23592263
MIRT1064205	hsa-miR-23a	CLIP-seq
MIRT1064206	hsa-miR-23b	CLIP-seq
MIRT1064207	hsa-miR-23c	CLIP-seq
MIRT1064208	hsa-miR-34b	CLIP-seq
MIRT1064209	hsa-miR-450b-5p	CLIP-seq
MIRT1064210	hsa-miR-518a-5p	CLIP-seq
MIRT1064211	hsa-miR-527	CLIP-seq
MIRT1064212	hsa-miR-9	CLIP-seq
MIRT2247571	hsa-miR-1275	CLIP-seq
MIRT2247572	hsa-miR-4260	CLIP-seq
MIRT2247573	hsa-miR-4457	CLIP-seq
MIRT2247574	hsa-miR-4488	CLIP-seq
MIRT2247575	hsa-miR-4665-5p	CLIP-seq
MIRT2247576	hsa-miR-4697-5p	CLIP-seq
MIRT2247577	hsa-miR-548ad	CLIP-seq

Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005125	Function	Cytokine activity	IBA
GO:0005125	Function	Cytokine activity	IEA
GO:0005149	Function	Interleukin-1 receptor binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IBA
GO:0005615	Component	Extracellular space	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0006954	Process	Inflammatory response	IBA
GO:0006954	Process	Inflammatory response	IEA
GO:0006955	Process	Immune response	IBA
GO:0006955	Process	Immune response	IEA
GO:0019221	Process	Cytokine-mediated signaling pathway	IBA
GO:0071222	Process	Cellular response to lipopolysaccharide	IBA

MIM	HGNC	e!Ensembl
615296	15552	ENSG00000136697

Q8WWZ1

Protein name

Interleukin-1 family member 10 (IL-1F10) (Family of interleukin 1-theta) (FIL1 theta) (Interleukin-1 HY2) (IL-1HY2) (Interleukin-1 theta) (IL-1 theta) (Interleukin-38) (IL-38)

Protein function

Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononu

PDB

5BOW

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00340	IL1	32 → 148	Interleukin-1 / 18	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.

Sequence

MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCCAEKICILPNRGLARTKVPIFLG
IQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPGW
FLCGPAEPQQPVQLTKESEPSARTKFYFEQSW

Sequence length

152

Interactions

View interactions

	KEGG		Reactome
	Cytokine-cytokine receptor interaction		Interleukin-38 signaling Interleukin-36 pathway

IL1F10 (interleukin 1 family member 10)