ATRN (attractin)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8455 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Attractin |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ATRN |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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DPPT-L, MGCA |
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Chromosome
Chromosome number
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20 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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20p13 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune ce |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||||||||||||
| UniProt ID | O75882 | ||||||||||||||||||||||||||||||||||||||||
| Protein name | Attractin (DPPT-L) (Mahogany homolog) | ||||||||||||||||||||||||||||||||||||||||
| Protein function | Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity rec | ||||||||||||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very | ||||||||||||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 1429 | ||||||||||||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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