Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	84460
Gene name	Zinc finger matrin-type 1
Gene symbol	ZMAT1
Synonyms (NCBI Gene)	-
Chromosome	X
Chromosome location	Xq22.1
Summary	This gene encodes a protein containing Cys2-His2 (C2H2)-type zinc fingers, which are similar to those found in the nuclear matrix protein matrin 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Show/Hide all (54)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018428	hsa-miR-335-5p	Microarray	18185580
MIRT709972	hsa-miR-548n	HITS-CLIP	19536157
MIRT709971	hsa-miR-548az-5p	HITS-CLIP	19536157
MIRT709970	hsa-miR-548t-5p	HITS-CLIP	19536157
MIRT709969	hsa-miR-6507-5p	HITS-CLIP	19536157
MIRT640813	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT640812	hsa-miR-1248	HITS-CLIP	23824327
MIRT640811	hsa-miR-3119	HITS-CLIP	23824327
MIRT640810	hsa-miR-27a-5p	HITS-CLIP	23824327
MIRT640809	hsa-miR-6740-5p	HITS-CLIP	23824327
MIRT640808	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT640807	hsa-miR-4674	HITS-CLIP	23824327
MIRT640806	hsa-miR-1587	HITS-CLIP	23824327
MIRT640805	hsa-miR-3620-5p	HITS-CLIP	23824327
MIRT709972	hsa-miR-548n	HITS-CLIP	19536157
MIRT709971	hsa-miR-548az-5p	HITS-CLIP	19536157
MIRT709970	hsa-miR-548t-5p	HITS-CLIP	19536157
MIRT709969	hsa-miR-6507-5p	HITS-CLIP	19536157
MIRT640813	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT640812	hsa-miR-1248	HITS-CLIP	23824327
MIRT640811	hsa-miR-3119	HITS-CLIP	23824327
MIRT640810	hsa-miR-27a-5p	HITS-CLIP	23824327
MIRT640809	hsa-miR-6740-5p	HITS-CLIP	23824327
MIRT640808	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT640807	hsa-miR-4674	HITS-CLIP	23824327
MIRT640806	hsa-miR-1587	HITS-CLIP	23824327
MIRT640805	hsa-miR-3620-5p	HITS-CLIP	23824327
MIRT1514077	hsa-miR-151-3p	CLIP-seq
MIRT1514078	hsa-miR-4275	CLIP-seq
MIRT1514079	hsa-miR-4463	CLIP-seq
MIRT1514080	hsa-miR-4499	CLIP-seq
MIRT1514081	hsa-miR-452	CLIP-seq
MIRT1514082	hsa-miR-4659a-3p	CLIP-seq
MIRT1514083	hsa-miR-4659b-3p	CLIP-seq
MIRT1514084	hsa-miR-4676-3p	CLIP-seq
MIRT1514085	hsa-miR-4778-3p	CLIP-seq
MIRT1514086	hsa-miR-4795-3p	CLIP-seq
MIRT1514087	hsa-miR-513a-3p	CLIP-seq
MIRT1514088	hsa-miR-579	CLIP-seq
MIRT2155060	hsa-miR-3692	CLIP-seq
MIRT2155061	hsa-miR-578	CLIP-seq
MIRT1514088	hsa-miR-579	CLIP-seq
MIRT2374990	hsa-miR-2116	CLIP-seq
MIRT2374991	hsa-miR-320a	CLIP-seq
MIRT2374992	hsa-miR-320b	CLIP-seq
MIRT2374993	hsa-miR-320c	CLIP-seq
MIRT2374994	hsa-miR-320d	CLIP-seq
MIRT2374995	hsa-miR-4257	CLIP-seq
MIRT2374996	hsa-miR-4329	CLIP-seq
MIRT2374997	hsa-miR-4330	CLIP-seq
MIRT2374998	hsa-miR-4429	CLIP-seq
MIRT2374999	hsa-miR-4677-5p	CLIP-seq
MIRT2375000	hsa-miR-4789-3p	CLIP-seq
MIRT2375001	hsa-miR-642b	CLIP-seq

Show/Hide all (5)

GO ID	Ontology	Definition	Evidence
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
301007	29377	ENSG00000166432

Q5H9K5

Protein name

Zinc finger matrin-type protein 1

Family and domains

Pfam

Accession	ID	Position in sequence	Type
PF12874	zf-met	56 → 80	Domain
PF12874	zf-met	121 → 145	Domain
PF12874	zf-met	175 → 199	Domain

Sequence

MESCSVTRLECSGAISAHCSLHLPGSSDSPASASQIAGTTDAIWNEQEKAELFTDKFCQV
CGVMLQFESQRISHYEGEKHAQNVSFYFQMHGEQNEVPGKKMKMHVENFQVHRYEGVDKN
KFCDLCNMMFSSPLIAQSHYVGKVHAKKLKQLMEEHDQASPSGFQPEMAFSMRTYVCHIC
SIAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQKARGLEAKT
CFRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAMEKQLPHSKKT
YDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRMCEQRFSHEA
SQTYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKARGLEPKTCFRKIGDS
SVETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLPAHDSKQRLD
SISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQK
RKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKK
SHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILGF

Sequence length

638

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Abnormality of neuronal migration	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Carcinoma Pancreatic Ductal	Inhibit	35392973	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Associate	32751923	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Associate	26191264	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	35392973	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Inhibit	35392973	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Inhibit	26191264	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZMAT1 (zinc finger matrin-type 1)