DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8445 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Dual specificity tyrosine phosphorylation regulated kinase 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DYRK2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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- |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q15 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine res |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q92630 | ||||||||||
| Protein name | Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) | ||||||||||
| Protein function | Serine/threonine-protein kinase involved in the regulation of the mitotic cell cycle, cell proliferation, apoptosis, organization of the cytoskeleton and neurite outgrowth. Functions in part via its role in ubiquitin-dependent proteasomal protei | ||||||||||
| PDB | 3K2L , 3KVW , 4AZF , 5LXC , 5LXD , 5ZTN , 6HDP , 6HDR , 6K0J , 7AKF , 7AKH , 7DG4 , 7DH3 , 7DH9 , 7DHC , 7DHH , 7DHK , 7DHN , 7DHO , 7DHV , 7DJO , 7DL6 , 8HLT | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Testis, after the onset of spermatogenesis. {ECO:0000269|PubMed:9748265}. | ||||||||||
| Sequence |
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| Sequence length | 601 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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