Gene Gene information from NCBI Gene database.
Entrez ID 84436
Gene name Zinc finger protein 528
Gene symbol ZNF528
Synonyms (NCBI Gene)
-
Chromosome 19
Chromosome location 19q13.41
miRNA miRNA information provided by mirtarbase database.
260
miRTarBase ID miRNA Experiments Reference
MIRT693384 hsa-miR-548c-3p HITS-CLIP 23313552
MIRT693383 hsa-miR-6771-3p HITS-CLIP 23313552
MIRT693382 hsa-miR-3675-3p HITS-CLIP 23313552
MIRT693381 hsa-miR-3926 HITS-CLIP 23313552
MIRT693380 hsa-miR-663b HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615580 29384 ENSG00000167555
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q3MIS6
Protein name Zinc finger protein 528
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 7 48 KRAB box Family
PF00096 zf-C2H2 213 235 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 241 263 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 269 291 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 297 319 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 325 347 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 353 375 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 381 403 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 409 431 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 437 459 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 465 487 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 493 515 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 521 543 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 549 571 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 577 599 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 605 627 Zinc finger, C2H2 type Domain
Sequence
Sequence length 628
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
Essential tremor Likely benign ClinVar
Disgenet
★★★☆☆
Reported in Unknown/Other Associations (≥2 sources)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Bone Diseases Associate 32722848
★☆☆☆☆
Found in Text Mining only
Cleft Lip Associate 28230599
★☆☆☆☆
Found in Text Mining only
Juvenile osteoporosis Associate 32722848
★☆☆☆☆
Found in Text Mining only
Neoplasms Associate 34440306
★☆☆☆☆
Found in Text Mining only
Osteosarcoma Associate 34440306
★☆☆☆☆
Found in Text Mining only