ACBD6 (acyl-CoA binding domain containing 6)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84320
Gene name Gene Name - the full gene name approved by the HGNC.
Acyl-CoA binding domain containing 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ACBD6
Synonyms (NCBI Gene) Gene synonyms aliases
NEDPM
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q25.2-q25.3
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(10)
miRTarBase ID miRNA Experiments Reference
MIRT041521 hsa-miR-193b-3p CLASH 23622248
MIRT762174 hsa-miR-3146 CLIP-seq
MIRT762175 hsa-miR-3148 CLIP-seq
MIRT762176 hsa-miR-323b-3p CLIP-seq
MIRT762177 hsa-miR-3674 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(11)
GO ID Ontology Definition Evidence Reference
GO:0000062 Function Fatty-acyl-CoA binding IBA
GO:0000062 Function Fatty-acyl-CoA binding IEA
GO:0000062 Function Fatty-acyl-CoA binding IMP 37951597
GO:0005515 Function Protein binding IPI 26621918, 32296183, 33961781
GO:0005634 Component Nucleus IDA 37951597
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
616352 23339 ENSG00000230124
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9BR61
Protein name Acyl-CoA-binding domain-containing protein 6
Protein function Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids. Plays a role in protein N-myristo
PDB 2COP
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00887 ACBP 43 → 123 Acyl CoA binding protein Domain
PF12796 Ank_2 162 → 255 Ankyrin repeats (3 copies) Repeat
Tissue specificity TISSUE SPECIFICITY: Detected in placenta and spleen (at protein level). Detected in placenta, umbilical cord blood, CD34-positive hematopoietic progenitor cells and bone marrow. {ECO:0000269|PubMed:18268358}.
Sequence
Sequence length 282
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    Mitochondrial Fatty Acid Beta-Oxidation
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Mental retardation intellectual disability N/A N/A GenCC
Show/Hide Text Mining Associations (3)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Motor Disorders Associate 38181310
Non alcoholic Fatty Liver Disease Associate 22215535
Stroke Associate 38181310