Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84285
Gene name Gene Name - the full gene name approved by the HGNC.
Eukaryotic translation initiation factor 1A domain containing
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
EIF1AD
Synonyms (NCBI Gene) Gene synonyms aliases
OBELIX, haponin
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q13.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT047654 hsa-miR-10a-5p CLASH 23622248
MIRT038809 hsa-miR-93-3p CLASH 23622248
MIRT037128 hsa-miR-877-3p CLASH 23622248
MIRT720282 hsa-miR-125b-5p HITS-CLIP 19536157
MIRT720281 hsa-miR-125a-5p HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003743 Function Translation initiation factor activity IEA
GO:0005515 Function Protein binding IPI 16189514, 21516116, 25416956, 31515488, 32296183
GO:0005634 Component Nucleus IBA 21873635
GO:0005654 Component Nucleoplasm IDA
GO:0006413 Process Translational initiation IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
618473 28147 ENSG00000175376
Protein
UniProt ID Q8N9N8
Protein name Probable RNA-binding protein EIF1AD (Eukaryotic translation initiation factor 1A domain-containing protein) (Haponin)
Protein function Plays a role into cellular response to oxidative stress. Decreases cell proliferation.
PDB 2DGY , 6ZXF , 6ZXG , 6ZXH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01176 eIF-1a 24 87 Translation initiation factor 1A / IF-1 Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in the glioblastoma cell line U-87MG, the embryonic kidney cell line HEK293, the pancreatic carcinoma cell line PANC-1, the breast carcinoma cell line MCF-7, the lung cancer cell line NCI-H460, and the chronic myelogenous leu
Sequence
MSQATKRKHVVKEVLGEHIVPSDQQQIVRVLRTPGNNLHEVETAQGQRFLVSMPSKYRKN
IWIKRGDFLIVDPIEEGEKVKAEISFV
LCKDHVRSLQKEGFWPEAFSEVAEKHNNRNRQT
QPELPAEPQLSGEESSSEDDSDLFVNTNRRQYHESEEESEEEEAA
Sequence length 165
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Melanoma melanoma rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340
View all (64 more)
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