Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84255
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier family 37 member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLC37A3
Synonyms (NCBI Gene) Gene synonyms aliases
SPX3
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q34
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021553 hsa-miR-142-3p Microarray 17612493
MIRT025190 hsa-miR-181a-5p Sequencing 20371350
MIRT028288 hsa-miR-32-5p Sequencing 20371350
MIRT534219 hsa-miR-3925-5p PAR-CLIP 20371350
MIRT534218 hsa-miR-3123 PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 29745899
GO:0005764 Component Lysosome IEA
GO:0005765 Component Lysosomal membrane IDA 29745899
GO:0005765 Component Lysosomal membrane IEA
GO:0005783 Component Endoplasmic reticulum IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
619137 20651 ENSG00000157800
Protein
UniProt ID Q8NCC5
Protein name Sugar phosphate exchanger 3 (Solute carrier family 37 member 3)
Protein function Unlike the other SLC37 members, lacks glucose-6-phosphate antiporter activity (PubMed:21949678). In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that ha
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07690 MFS_1 23 419 Major Facilitator Superfamily Family
Tissue specificity TISSUE SPECIFICITY: Expressed in liver, kidney, intestine and pancreas. {ECO:0000269|PubMed:21949678}.
Sequence
Sequence length 494
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Retinitis Pigmentosa retinitis pigmentosa N/A N/A GenCC
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 36773462
Congenital Hyperinsulinism Associate 23869231
Diabetes Mellitus Type 1 Associate 36773462
Neoplasm Metastasis Associate 36773462
Retinitis Pigmentosa Associate 35486108
Tuberculosis Associate 36476775