Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84243
Gene name Gene Name - the full gene name approved by the HGNC.
ZDHHC palmitoyltransferase 18
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZDHHC18
Synonyms (NCBI Gene) Gene synonyms aliases
DHHC-18, DHHC18
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p36.11
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT066814 hsa-miR-338-3p PAR-CLIP 20371350
MIRT113580 hsa-miR-19a-3p PAR-CLIP 20371350
MIRT113581 hsa-miR-19b-3p PAR-CLIP 20371350
MIRT561278 hsa-miR-6771-3p PAR-CLIP 20371350
MIRT561277 hsa-miR-1295b-5p PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0005783 Component Endoplasmic reticulum IBA 21873635
GO:0005794 Component Golgi apparatus IBA 21873635
GO:0005794 Component Golgi apparatus IDA 16647879
GO:0006612 Process Protein targeting to membrane IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
620963 20712 ENSG00000204160
Protein
UniProt ID Q9NUE0
Protein name Palmitoyltransferase ZDHHC18 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 18) (DHHC-18) (Zinc finger DHHC domain-containing protein 18)
Protein function Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as CGAS, HRAS and LCK (PubMed:23034182, PubMed:27481942, PubMed:35438208). Acts as a negative regulator of the cGAS-STING pathway be mediating pa
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01529 DHHC 187 316 DHHC palmitoyltransferase Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16647879}.
Sequence
MKDCEYQQISPGAAPLPASPGARRPGPAASPTPGPGPAPPAAPAPPRWSSSGSGSGSGSG
SLGRRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILTTTGLFFVFDCPYLARKL
TLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATVCEAAALEKQIDNTGSSTYRPPPRTR
EVLINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAF
ILSLSFLTAFIFACVVTHLTLRAQGSNFLSTLKETPASVLELVICFFSIWSILGLSGFHT
YLVASNLTTNEDIKGS
WSSKRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRGFVQS
DTVLPSPIRSDEPACRAKPDASMVGGHP
Sequence length 388
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Lymphoblastic leukemia Precursor Cell Lymphoblastic Leukemia Lymphoma rs387906351, rs104894562, rs398122513, rs398122840, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699
View all (13 more)
28090653
Unknown
Disease term Disease name Evidence References Source
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease 30940143 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Glioblastoma Associate 30658672
Glioma Associate 30658672