Gene Gene information from NCBI Gene database.
Entrez ID 84243
Gene name ZDHHC palmitoyltransferase 18
Gene symbol ZDHHC18
Synonyms (NCBI Gene)
DHHC-18DHHC18
Chromosome 1
Chromosome location 1p36.11
miRNA miRNA information provided by mirtarbase database.
378
miRTarBase ID miRNA Experiments Reference
MIRT066814 hsa-miR-338-3p PAR-CLIP 20371350
MIRT113580 hsa-miR-19a-3p PAR-CLIP 20371350
MIRT113581 hsa-miR-19b-3p PAR-CLIP 20371350
MIRT561278 hsa-miR-6771-3p PAR-CLIP 20371350
MIRT561277 hsa-miR-1295b-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0002376 Process Immune system process IEA
GO:0005783 Component Endoplasmic reticulum IBA
GO:0005794 Component Golgi apparatus IBA
GO:0005794 Component Golgi apparatus IDA 35438208
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620963 20712 ENSG00000204160
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NUE0
Protein name Palmitoyltransferase ZDHHC18 (EC 2.3.1.225) (DHHC domain-containing cysteine-rich protein 18) (DHHC-18) (Zinc finger DHHC domain-containing protein 18)
Protein function Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as CGAS, HRAS and LCK (PubMed:23034182, PubMed:27481942, PubMed:35438208). Acts as a negative regulator of the cGAS-STING pathway be mediating pa
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01529 DHHC 187 316 DHHC palmitoyltransferase Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16647879}.
Sequence
MKDCEYQQISPGAAPLPASPGARRPGPAASPTPGPGPAPPAAPAPPRWSSSGSGSGSGSG
SLGRRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILTTTGLFFVFDCPYLARKL
TLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATVCEAAALEKQIDNTGSSTYRPPPRTR
EVLINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAF
ILSLSFLTAFIFACVVTHLTLRAQGSNFLSTLKETPASVLELVICFFSIWSILGLSGFHT
YLVASNLTTNEDIKGS
WSSKRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRGFVQS
DTVLPSPIRSDEPACRAKPDASMVGGHP
Sequence length 388
Interactions View interactions