Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	84216
Gene name Gene Name - the full gene name approved by the HGNC.	Transmembrane protein 117
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TMEM117
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q12

Show/Hide all(83)

miRTarBase ID	miRNA	Experiments	Reference
MIRT543222	hsa-miR-8066	PAR-CLIP	21572407
MIRT543221	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT543220	hsa-miR-3168	PAR-CLIP	21572407
MIRT543219	hsa-miR-148b-5p	PAR-CLIP	21572407
MIRT543218	hsa-miR-6874-3p	PAR-CLIP	21572407
MIRT543217	hsa-miR-5584-3p	PAR-CLIP	21572407
MIRT543216	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT543215	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT543214	hsa-miR-302a-5p	PAR-CLIP	21572407
MIRT543213	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT543212	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT543211	hsa-miR-2116-5p	PAR-CLIP	21572407
MIRT543210	hsa-miR-4477a	PAR-CLIP	21572407
MIRT442878	hsa-miR-95-5p	PAR-CLIP	22100165
MIRT442877	hsa-miR-3199	PAR-CLIP	22100165
MIRT442875	hsa-miR-8052	PAR-CLIP	22100165
MIRT442876	hsa-miR-365a-5p	PAR-CLIP	22100165
MIRT442874	hsa-miR-365b-5p	PAR-CLIP	22100165
MIRT442873	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT442872	hsa-miR-5010-3p	PAR-CLIP	22100165
MIRT543222	hsa-miR-8066	PAR-CLIP	21572407
MIRT543221	hsa-miR-5571-5p	PAR-CLIP	21572407
MIRT543220	hsa-miR-3168	PAR-CLIP	21572407
MIRT543219	hsa-miR-148b-5p	PAR-CLIP	21572407
MIRT543218	hsa-miR-6874-3p	PAR-CLIP	21572407
MIRT543217	hsa-miR-5584-3p	PAR-CLIP	21572407
MIRT543216	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT543215	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT543214	hsa-miR-302a-5p	PAR-CLIP	21572407
MIRT543213	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT543212	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT543211	hsa-miR-2116-5p	PAR-CLIP	21572407
MIRT543210	hsa-miR-4477a	PAR-CLIP	21572407
MIRT442878	hsa-miR-95-5p	PAR-CLIP	22100165
MIRT442877	hsa-miR-3199	PAR-CLIP	22100165
MIRT442875	hsa-miR-8052	PAR-CLIP	22100165
MIRT442876	hsa-miR-365a-5p	PAR-CLIP	22100165
MIRT442874	hsa-miR-365b-5p	PAR-CLIP	22100165
MIRT442873	hsa-miR-192-3p	PAR-CLIP	22100165
MIRT442872	hsa-miR-5010-3p	PAR-CLIP	22100165
MIRT1430045	hsa-miR-1231	CLIP-seq
MIRT1430046	hsa-miR-1251	CLIP-seq
MIRT1430047	hsa-miR-1324	CLIP-seq
MIRT739590	hsa-miR-19a	CLIP-seq
MIRT739589	hsa-miR-19b	CLIP-seq
MIRT1430048	hsa-miR-216b	CLIP-seq
MIRT1430049	hsa-miR-3121-3p	CLIP-seq
MIRT1430050	hsa-miR-3189-3p	CLIP-seq
MIRT1430051	hsa-miR-3192	CLIP-seq
MIRT1430052	hsa-miR-323b-5p	CLIP-seq
MIRT1430053	hsa-miR-3611	CLIP-seq
MIRT1430054	hsa-miR-3675-3p	CLIP-seq
MIRT1430055	hsa-miR-3691-3p	CLIP-seq
MIRT1430056	hsa-miR-3692	CLIP-seq
MIRT1430057	hsa-miR-3913-3p	CLIP-seq
MIRT1430058	hsa-miR-4288	CLIP-seq
MIRT1430059	hsa-miR-4314	CLIP-seq
MIRT1430060	hsa-miR-4453	CLIP-seq
MIRT1430061	hsa-miR-4538	CLIP-seq
MIRT1430062	hsa-miR-4646-5p	CLIP-seq
MIRT1430063	hsa-miR-4652-3p	CLIP-seq
MIRT1430064	hsa-miR-4684-5p	CLIP-seq
MIRT1430065	hsa-miR-502-5p	CLIP-seq
MIRT1430066	hsa-miR-515-5p	CLIP-seq
MIRT1430067	hsa-miR-544	CLIP-seq
MIRT1430068	hsa-miR-570	CLIP-seq
MIRT1430069	hsa-miR-579	CLIP-seq
MIRT1430070	hsa-miR-599	CLIP-seq
MIRT1430071	hsa-miR-624	CLIP-seq
MIRT1430072	hsa-miR-632	CLIP-seq
MIRT1430073	hsa-miR-767-3p	CLIP-seq
MIRT1430074	hsa-miR-942	CLIP-seq
MIRT739590	hsa-miR-19a	CLIP-seq
MIRT739589	hsa-miR-19b	CLIP-seq
MIRT739590	hsa-miR-19a	CLIP-seq
MIRT739589	hsa-miR-19b	CLIP-seq
MIRT2350454	hsa-miR-4642	CLIP-seq
MIRT739590	hsa-miR-19a	CLIP-seq
MIRT739589	hsa-miR-19b	CLIP-seq
MIRT2395917	hsa-miR-513a-3p	CLIP-seq
MIRT2395918	hsa-miR-548u	CLIP-seq
MIRT739590	hsa-miR-19a	CLIP-seq
MIRT739589	hsa-miR-19b	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003674	Function	Molecular_function	ND
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005886	Component	Plasma membrane	IDA	27391701
GO:0016021	Component	Integral component of membrane	IEA
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IBA	21873635
GO:0070059	Process	Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	28285135

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q9H0C3

Protein name

Transmembrane protein 117

Protein function

Involved in endoplasmic reticulum (ER) stress-induced cell death pathway.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15113	TMEM117	4 → 416	TMEM117 protein family	Family

Sequence

MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPR
GVGWRILKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLF
IFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKP
YPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRA
FLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITG
KWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWE
WRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKN
EPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKS
SHLTSENLSSQLNESTSATEADQDPTTSKSTPTN

Sequence length

514

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Cholestasis	Cholestasis	rs121909103, rs751511532, rs376368459, rs762702807, rs1578490102, rs1578499691, rs1578504946, rs1317656688, rs199791850, rs1452792080, rs1578491039	26881866

Show/Hide Unknown Diseases (3)

Disease term	Disease name	Evidence	Source
Unknown
Inflammatory Bowel Disease	Inflammatory Bowel Disease		GWAS
Oligodendroglioma	Oligodendroglioma		GWAS
Glioblastoma	Glioblastoma	CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587	GWAS, CBGDA

TMEM117 (transmembrane protein 117)