ZNF541 (zinc finger protein 541)

Gene

• Entrez ID: 84215
• Gene name: Zinc finger protein 541
• Gene symbol: ZNF541
• Synonyms (NCBI Gene): -
• Chromosome: 19
• Chromosome location: 19q13.33

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1528533	hsa-miR-1299	CLIP-seq
MIRT1528534	hsa-miR-1321	CLIP-seq
MIRT1528535	hsa-miR-185	CLIP-seq
MIRT1528536	hsa-miR-298	CLIP-seq
MIRT1528537	hsa-miR-3153	CLIP-seq
MIRT1528538	hsa-miR-3154	CLIP-seq
MIRT1528539	hsa-miR-3175	CLIP-seq
MIRT1528540	hsa-miR-3179	CLIP-seq
MIRT1528541	hsa-miR-3189-5p	CLIP-seq
MIRT1528542	hsa-miR-3199	CLIP-seq
MIRT1528543	hsa-miR-3202	CLIP-seq
MIRT1528544	hsa-miR-3612	CLIP-seq
MIRT1528545	hsa-miR-4270	CLIP-seq
MIRT1528546	hsa-miR-4306	CLIP-seq
MIRT1528547	hsa-miR-4441	CLIP-seq
MIRT1528548	hsa-miR-4443	CLIP-seq
MIRT1528549	hsa-miR-4447	CLIP-seq
MIRT1528550	hsa-miR-4472	CLIP-seq
MIRT1528551	hsa-miR-4533	CLIP-seq
MIRT1528552	hsa-miR-4644	CLIP-seq
MIRT1528553	hsa-miR-4723-5p	CLIP-seq
MIRT1528554	hsa-miR-4728-5p	CLIP-seq
MIRT1528555	hsa-miR-4739	CLIP-seq
MIRT1528556	hsa-miR-4740-5p	CLIP-seq
MIRT1528557	hsa-miR-4756-5p	CLIP-seq
MIRT1528558	hsa-miR-4760-3p	CLIP-seq
MIRT1528559	hsa-miR-650	CLIP-seq
MIRT1528560	hsa-miR-875-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000118	Component	Histone deacetylase complex	IBA
GO:0000118	Component	Histone deacetylase complex	IEA
GO:0000118	Component	Histone deacetylase complex	ISS
GO:0003714	Function	Transcription corepressor activity	IBA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005667	Component	Transcription regulator complex	IBA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	ISS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007140	Process	Male meiotic nuclear division	IEA
GO:0007140	Process	Male meiotic nuclear division	ISS
GO:0007283	Process	Spermatogenesis	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IBA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	ISS
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0051321	Process	Meiotic cell cycle	IEA

Other IDs

• MIM: 619942
• HGNC: 25294
• e!Ensembl: ENSG00000118156

Protein

• UniProt ID: Q9H0D2
• Protein name: Zinc finger protein 541
• Protein function: Transcription regulator which is essential for male fertility and for the completion of meiotic prophase in spermatocytes. Regulates progression of the pachytene stage of meiotic prophase by activating the expression of genes involved in meiosis
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	140 → 162	Zinc finger, C2H2 type	Domain
  PF13912	zf-C2H2_6	167 → 193		Domain
  PF01448	ELM2	1055 → 1110	ELM2 domain	Family
  PF13912	zf-C2H2_6	1288 → 1314		Domain

• Sequence:

  MDQYSLGDEGALPSEMHLPSFSESQGLNCSDTLNRDLGPNTRGFLYAGLSGLDPDPSLPT
  PDMSSEVLEDNLDTLSLYSGKDSDSVKLLEEYADSESQASLQDLGLGVLKAKEADEGGRA
  TSGSARKGKRQHSSPQNPLLDCSLCGKVFSSASSLSKHYLTHSQERKHVCKICSKAFKRQ
  DHLTGHMLTHQKTKPFVCIEQGCSKSYCDYRSLRRHYEVHHGLCILKEAPPEEEACGDSP
  HAHESAGQPPPSSLRSLVPPEARSPGSLLPHRDLLRRIVSSIVHQKTPSPGPAPAGASDS
  EGRNTACPCPASSGSSSCTPAGPHAAPAALDTELPEEPCLPQKEPATDVFTAPNSRAAEN
  GAPDPPEPEPDTALLQARSTAECWPEGGSVPACLPLFRGQTVPASSQPSSHSFQWLRNLP
  GCPKSKGNNVFVVHKPSAVPSREGSESGPGPSSGSPSEESPPGPGGGLEDALPFPAALLR
  VPAEAPSDPRSASGEDDPCAPKKVKVDCDSFLCQNPGEPGLQEAQKAGGLPADASPLFRQ
  LFLKSQEPLVSHEQMQVFQMITKSQRIFSHAQVAAVSSQLPAPEGKPAALRPLQGPWPQQ
  PPPLAPAVDSLHAGPGNPEAEGSPARRRKTTPGVPREASPGSTRRDAKGGLKVAAVPTPL
  AAPSLDPSRNPDISSLAKQLRSSKGTLDLEDIFPSTGQRQTQLGGEEPPGASLPGKQAPA
  ENGAASRITKGEKGPACSRGGGYRLLGNPRAPRFSGFRKEKAKMDMCCAASPSQVAMASF
  SSAGPPADPSKSKLTIFSRIQGGNIYRLPHPVKEENVAGRGNQQNGSPTDWTKPRSTFVC
  KNCSQMFYTEKGLSSHMCFHSDQWPSPRGKQEPQVFGTEFCKPLRQVLRPEGDRHSPPGT
  KKPLDPTAAAPLVVPQSIPVVPVTRHIGSMAMGQEKDGEERDSKESSQQRKRKKRPPPST
  AGEPGPAGCHQSRLRSPMFLVDCLLKGLFQCSPYTPPPMLSPIREGSGVYFNTLCSTSTQ
  ASPDQLISSMLDQVDGSFGICVVKDDTKISIEPHINIGSRFQAEIPELQERSLAGTDEHV
  ASLVWKPWGDMMISSETQDRVTELCNVACSSVMPGGGTNLELALHCLHEAQGNVQVALET
  LLLRGPHKPRTHLLADYRYTGSDVWTPIEKRLFKKAFYAHKKDFYLIHKMIQTKTVAQCV
  EYYYIWKKMIKFDCGRAPGLEKRVKREPEEVERTEEKVPCSPRERPSHHPTPKLKTKSYR
  RESILSSSPNAGSKRTPELLGSAESQGIFPCRECERVFDKIKSRNAHMKRHRLQDHVEPI
  IRVKWPVKPFQLKEEELGADIGPLQW

• Sequence length: 1346