ANTXR1 (ANTXR cell adhesion molecule 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 84168 |
| Gene name | ANTXR cell adhesion molecule 1 |
| Gene symbol | ANTXR1 |
| Synonyms (NCBI Gene) |
ATRGAPOTEM8
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| Chromosome | 2 |
| Chromosome location | 2p13.3 |
| Summary | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causat |
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SNPs
SNP information provided by dbSNP.
8
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miRNA
miRNA information provided by mirtarbase database.
566
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9H6X2 | ||||||||||||||||||||
| Protein name | Anthrax toxin receptor 1 (Tumor endothelial marker 8) | ||||||||||||||||||||
| Protein function | Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton and thereby plays an important role in normal extracellular matrix (ECM) homeostasis. Mediates adhesion of cells to type | ||||||||||||||||||||
| PDB | 3N2N , 6ADL , 6ADM , 6ADR , 6CX1 | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. {ECO:0000269|PubMed:15777794}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 564 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
54
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