Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	84138
Gene name	Solute carrier family 7 member 6 opposite strand
Gene symbol	SLC7A6OS
Synonyms (NCBI Gene)	EPM12Iwr1
Chromosome	16
Chromosome location	16q22.1

159

Show/Hide all (159)

miRTarBase ID	miRNA	Experiments	Reference
MIRT664723	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT664722	hsa-miR-4780	HITS-CLIP	23824327
MIRT664721	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT664720	hsa-miR-4287	HITS-CLIP	23824327
MIRT664719	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT664718	hsa-miR-1292-5p	HITS-CLIP	23824327
MIRT664717	hsa-miR-4471	HITS-CLIP	23824327
MIRT664716	hsa-miR-8059	HITS-CLIP	23824327
MIRT664715	hsa-miR-203a-5p	HITS-CLIP	23824327
MIRT664714	hsa-miR-1273g-5p	HITS-CLIP	23824327
MIRT664713	hsa-miR-623	HITS-CLIP	23824327
MIRT447664	hsa-miR-500a-5p	PAR-CLIP	22100165
MIRT447663	hsa-miR-501-5p	PAR-CLIP	22100165
MIRT447662	hsa-miR-4786-5p	PAR-CLIP	22100165
MIRT447661	hsa-miR-769-5p	PAR-CLIP	22100165
MIRT447660	hsa-miR-3672	PAR-CLIP	22100165
MIRT447659	hsa-miR-6864-3p	PAR-CLIP	22100165
MIRT447664	hsa-miR-500a-5p	PAR-CLIP	22100165
MIRT447663	hsa-miR-501-5p	PAR-CLIP	22100165
MIRT447662	hsa-miR-4786-5p	PAR-CLIP	22100165
MIRT447661	hsa-miR-769-5p	PAR-CLIP	22100165
MIRT447660	hsa-miR-3672	PAR-CLIP	22100165
MIRT447659	hsa-miR-6864-3p	PAR-CLIP	22100165
MIRT664723	hsa-miR-6887-3p	HITS-CLIP	23824327
MIRT664722	hsa-miR-4780	HITS-CLIP	23824327
MIRT664721	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT664720	hsa-miR-4287	HITS-CLIP	23824327
MIRT664719	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT664718	hsa-miR-1292-5p	HITS-CLIP	23824327
MIRT664717	hsa-miR-4471	HITS-CLIP	23824327
MIRT664716	hsa-miR-8059	HITS-CLIP	23824327
MIRT664715	hsa-miR-203a-5p	HITS-CLIP	23824327
MIRT664714	hsa-miR-1273g-5p	HITS-CLIP	23824327
MIRT664713	hsa-miR-623	HITS-CLIP	23824327
MIRT447664	hsa-miR-500a-5p	PAR-CLIP	22100165
MIRT447663	hsa-miR-501-5p	PAR-CLIP	22100165
MIRT447662	hsa-miR-4786-5p	PAR-CLIP	22100165
MIRT447661	hsa-miR-769-5p	PAR-CLIP	22100165
MIRT447660	hsa-miR-3672	PAR-CLIP	22100165
MIRT447659	hsa-miR-6864-3p	PAR-CLIP	22100165
MIRT447664	hsa-miR-500a-5p	PAR-CLIP	22100165
MIRT447663	hsa-miR-501-5p	PAR-CLIP	22100165
MIRT447662	hsa-miR-4786-5p	PAR-CLIP	22100165
MIRT447661	hsa-miR-769-5p	PAR-CLIP	22100165
MIRT447660	hsa-miR-3672	PAR-CLIP	22100165
MIRT447659	hsa-miR-6864-3p	PAR-CLIP	22100165
MIRT1368347	hsa-miR-1273g	CLIP-seq
MIRT1368348	hsa-miR-1292	CLIP-seq
MIRT1368349	hsa-miR-203	CLIP-seq
MIRT1368350	hsa-miR-3065-3p	CLIP-seq
MIRT1368351	hsa-miR-3140-5p	CLIP-seq
MIRT1368352	hsa-miR-4291	CLIP-seq
MIRT2109406	hsa-miR-1182	CLIP-seq
MIRT2109407	hsa-miR-1183	CLIP-seq
MIRT2109408	hsa-miR-1273e	CLIP-seq
MIRT2109409	hsa-miR-1304	CLIP-seq
MIRT2109410	hsa-miR-1827	CLIP-seq
MIRT2109411	hsa-miR-190	CLIP-seq
MIRT2109412	hsa-miR-190b	CLIP-seq
MIRT2109413	hsa-miR-548g	CLIP-seq
MIRT2109414	hsa-miR-607	CLIP-seq
MIRT2332570	hsa-miR-3140-3p	CLIP-seq
MIRT2332571	hsa-miR-3667-3p	CLIP-seq
MIRT2332572	hsa-miR-3692	CLIP-seq
MIRT2332573	hsa-miR-451	CLIP-seq
MIRT2332574	hsa-miR-513b	CLIP-seq
MIRT2459911	hsa-miR-1193	CLIP-seq
MIRT2459912	hsa-miR-1208	CLIP-seq
MIRT2109408	hsa-miR-1273e	CLIP-seq
MIRT1368348	hsa-miR-1292	CLIP-seq
MIRT2109411	hsa-miR-190	CLIP-seq
MIRT2109412	hsa-miR-190b	CLIP-seq
MIRT1368349	hsa-miR-203	CLIP-seq
MIRT2459913	hsa-miR-298	CLIP-seq
MIRT2332570	hsa-miR-3140-3p	CLIP-seq
MIRT2459914	hsa-miR-4318	CLIP-seq
MIRT2459915	hsa-miR-4420	CLIP-seq
MIRT2459916	hsa-miR-4632	CLIP-seq
MIRT2459917	hsa-miR-4654	CLIP-seq
MIRT2459918	hsa-miR-4769-5p	CLIP-seq
MIRT2459919	hsa-miR-4803	CLIP-seq
MIRT2459920	hsa-miR-483-3p	CLIP-seq
MIRT2459921	hsa-miR-5096	CLIP-seq
MIRT2459922	hsa-miR-541	CLIP-seq
MIRT2459923	hsa-miR-654-5p	CLIP-seq
MIRT2459924	hsa-miR-922	CLIP-seq
MIRT2459911	hsa-miR-1193	CLIP-seq
MIRT2459916	hsa-miR-4632	CLIP-seq
MIRT2459917	hsa-miR-4654	CLIP-seq
MIRT2459918	hsa-miR-4769-5p	CLIP-seq
MIRT2459922	hsa-miR-541	CLIP-seq
MIRT2459923	hsa-miR-654-5p	CLIP-seq
MIRT2459911	hsa-miR-1193	CLIP-seq
MIRT2459912	hsa-miR-1208	CLIP-seq
MIRT2626971	hsa-miR-1263	CLIP-seq
MIRT2626972	hsa-miR-1265	CLIP-seq
MIRT2109408	hsa-miR-1273e	CLIP-seq
MIRT2109410	hsa-miR-1827	CLIP-seq
MIRT2109411	hsa-miR-190	CLIP-seq
MIRT2109412	hsa-miR-190b	CLIP-seq
MIRT1368349	hsa-miR-203	CLIP-seq
MIRT2626973	hsa-miR-214	CLIP-seq
MIRT2459913	hsa-miR-298	CLIP-seq
MIRT2332570	hsa-miR-3140-3p	CLIP-seq
MIRT2626974	hsa-miR-3619-5p	CLIP-seq
MIRT2332571	hsa-miR-3667-3p	CLIP-seq
MIRT2626975	hsa-miR-3685	CLIP-seq
MIRT2332572	hsa-miR-3692	CLIP-seq
MIRT2626976	hsa-miR-384	CLIP-seq
MIRT1368352	hsa-miR-4291	CLIP-seq
MIRT2459914	hsa-miR-4318	CLIP-seq
MIRT2459915	hsa-miR-4420	CLIP-seq
MIRT2626977	hsa-miR-4436b-3p	CLIP-seq
MIRT2626978	hsa-miR-4496	CLIP-seq
MIRT2459916	hsa-miR-4632	CLIP-seq
MIRT2459917	hsa-miR-4654	CLIP-seq
MIRT2626979	hsa-miR-4760-5p	CLIP-seq
MIRT2626980	hsa-miR-4764-3p	CLIP-seq
MIRT2459918	hsa-miR-4769-5p	CLIP-seq
MIRT2459919	hsa-miR-4803	CLIP-seq
MIRT2459920	hsa-miR-483-3p	CLIP-seq
MIRT2459921	hsa-miR-5096	CLIP-seq
MIRT2459922	hsa-miR-541	CLIP-seq
MIRT2626981	hsa-miR-618	CLIP-seq
MIRT2459923	hsa-miR-654-5p	CLIP-seq
MIRT2626982	hsa-miR-761	CLIP-seq
MIRT2459924	hsa-miR-922	CLIP-seq
MIRT2626983	hsa-miR-940	CLIP-seq
MIRT2459911	hsa-miR-1193	CLIP-seq
MIRT2459912	hsa-miR-1208	CLIP-seq
MIRT2626971	hsa-miR-1263	CLIP-seq
MIRT2626972	hsa-miR-1265	CLIP-seq
MIRT2109408	hsa-miR-1273e	CLIP-seq
MIRT1368348	hsa-miR-1292	CLIP-seq
MIRT2109411	hsa-miR-190	CLIP-seq
MIRT2109412	hsa-miR-190b	CLIP-seq
MIRT1368349	hsa-miR-203	CLIP-seq
MIRT2626973	hsa-miR-214	CLIP-seq
MIRT2459913	hsa-miR-298	CLIP-seq
MIRT2332570	hsa-miR-3140-3p	CLIP-seq
MIRT2626974	hsa-miR-3619-5p	CLIP-seq
MIRT2332571	hsa-miR-3667-3p	CLIP-seq
MIRT2332572	hsa-miR-3692	CLIP-seq
MIRT1368352	hsa-miR-4291	CLIP-seq
MIRT2459914	hsa-miR-4318	CLIP-seq
MIRT2459915	hsa-miR-4420	CLIP-seq
MIRT2626977	hsa-miR-4436b-3p	CLIP-seq
MIRT2626978	hsa-miR-4496	CLIP-seq
MIRT2459916	hsa-miR-4632	CLIP-seq
MIRT2459917	hsa-miR-4654	CLIP-seq
MIRT2626979	hsa-miR-4760-5p	CLIP-seq
MIRT2459918	hsa-miR-4769-5p	CLIP-seq
MIRT2459919	hsa-miR-4803	CLIP-seq
MIRT2459920	hsa-miR-483-3p	CLIP-seq
MIRT2459921	hsa-miR-5096	CLIP-seq
MIRT2459922	hsa-miR-541	CLIP-seq
MIRT2459923	hsa-miR-654-5p	CLIP-seq
MIRT2626982	hsa-miR-761	CLIP-seq
MIRT2459924	hsa-miR-922	CLIP-seq

Show/Hide all (5)

GO ID	Ontology	Definition	Evidence
GO:0002244	Process	Hematopoietic progenitor cell differentiation	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0015031	Process	Protein transport	IEA
GO:0032502	Process	Developmental process	IBA

MIM	HGNC	e!Ensembl
619192	25807	ENSG00000103061

Q96CW6

Protein name

Probable RNA polymerase II nuclear localization protein SLC7A6OS (ADAMS proteinase-related protein) (Solute carrier family 7 member 6 opposite strand transcript)

Protein function

Directs RNA polymerase II nuclear import.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08574	Iwr1	194 → 257	Transcription factor Iwr1	Family

Sequence

MEAARTAVLRVKRKRSAEPAEALVLACKRLRSDAVESAAQKTSEGLERAAENNVFHLVAT
VCSQEEPVQPLLREVLRPSRDSQQRVRRNLRASAREVRQEGRYRVLSSRRSLGTTSSGQE
SEYTPGNPEAAGNSGFQLLDLVHEEGEPEAASAGSCKTSDPDVILCNSVELIRERLTVSE
DGPGVRRQEEQKHDDYVYDIYYLETATPGWIENILSVQPYSQEWELVNDDQEPEDIYDDE
DDENSENNWRNEYPEEESSDGDEDSRGSADYNSLSEEERGSSRQRMWSKYPLDVQKEFGY
DSPHDLDSD

Sequence length

309

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Clear cell carcinoma of kidney	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EPILEPSY	—	Disgenet, GenCC Disgenet, GenCC	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Epilepsy, progressive myoclonic, 12	Uncertain significance	ClinVar ClinVar, Disgenet, GWAS catalog, HPO ClinVar, Disgenet, GWAS catalog, HPO ClinVar, Disgenet, GWAS catalog, HPO	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
Familial cancer of breast	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

SLC7A6OS (solute carrier family 7 member 6 opposite strand)