Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	84133
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc and ring finger 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNRF3
Synonyms (NCBI Gene) Gene synonyms aliases	BK747E2.3, RNF203
Chromosome Chromosome number	22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	22q12.1

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miRTarBase ID	miRNA	Experiments	Reference
MIRT027017	hsa-miR-103a-3p	Sequencing	20371350
MIRT031450	hsa-miR-16-5p	Sequencing	20371350
MIRT042789	hsa-miR-339-5p	CLASH	23622248
MIRT438327	hsa-miR-146b-5p	qRT-PCR	24064622
MIRT438327	hsa-miR-146b-5p	qRT-PCR	24064622
MIRT462929	hsa-miR-34b-3p	PAR-CLIP	23592263
MIRT462928	hsa-miR-890	PAR-CLIP	23592263
MIRT370507	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT370516	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT370517	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT370519	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT370506	hsa-miR-940	PAR-CLIP	23592263
MIRT462927	hsa-miR-25-3p	PAR-CLIP	23592263
MIRT462926	hsa-miR-32-5p	PAR-CLIP	23592263
MIRT462925	hsa-miR-363-3p	PAR-CLIP	23592263
MIRT462924	hsa-miR-367-3p	PAR-CLIP	23592263
MIRT462923	hsa-miR-92a-3p	PAR-CLIP	23592263
MIRT462922	hsa-miR-92b-3p	PAR-CLIP	23592263
MIRT462921	hsa-miR-3614-5p	PAR-CLIP	23592263
MIRT462920	hsa-miR-6500-3p	PAR-CLIP	23592263
MIRT462919	hsa-miR-4257	PAR-CLIP	23592263
MIRT462918	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT462917	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT462916	hsa-miR-1292-3p	PAR-CLIP	23592263
MIRT462915	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT462914	hsa-miR-1827	PAR-CLIP	23592263
MIRT462913	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT462912	hsa-miR-6134	PAR-CLIP	23592263
MIRT462911	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT462910	hsa-miR-6086	PAR-CLIP	23592263
MIRT462909	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT462908	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT462907	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT462906	hsa-miR-711	PAR-CLIP	23592263
MIRT462905	hsa-miR-3612	PAR-CLIP	23592263
MIRT462904	hsa-miR-650	PAR-CLIP	23592263
MIRT462903	hsa-miR-1294	PAR-CLIP	23592263
MIRT462902	hsa-miR-7703	PAR-CLIP	23592263
MIRT462901	hsa-miR-4325	PAR-CLIP	23592263
MIRT462900	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT462899	hsa-miR-4776-5p	PAR-CLIP	23592263
MIRT462898	hsa-miR-4535	PAR-CLIP	23592263
MIRT462897	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT087424	hsa-miR-15a-5p	PAR-CLIP	22100165
MIRT087425	hsa-miR-15b-5p	PAR-CLIP	22100165
MIRT031450	hsa-miR-16-5p	PAR-CLIP	22100165
MIRT087426	hsa-miR-195-5p	PAR-CLIP	22100165
MIRT087428	hsa-miR-424-5p	PAR-CLIP	22100165
MIRT087429	hsa-miR-497-5p	PAR-CLIP	22100165
MIRT087435	hsa-miR-6838-5p	PAR-CLIP	22100165
MIRT444126	hsa-miR-503-5p	PAR-CLIP	22100165
MIRT444125	hsa-miR-646	PAR-CLIP	22100165
MIRT444124	hsa-miR-103b	PAR-CLIP	22100165
MIRT444123	hsa-miR-3661	PAR-CLIP	22100165
MIRT444122	hsa-miR-631	PAR-CLIP	22100165
MIRT087431	hsa-miR-4524a-5p	PAR-CLIP	22100165
MIRT087433	hsa-miR-4524b-5p	PAR-CLIP	22100165
MIRT444121	hsa-miR-376a-3p	PAR-CLIP	22100165
MIRT444120	hsa-miR-376b-3p	PAR-CLIP	22100165
MIRT444119	hsa-miR-192-5p	PAR-CLIP	22100165
MIRT444118	hsa-miR-215-5p	PAR-CLIP	22100165
MIRT438327	hsa-miR-146b-5p	Luciferase reporter assay, qRT-PCR, Western blot	26549292
MIRT438327	hsa-miR-146b-5p	Luciferase reporter assay, qRT-PCR	25547151
MIRT438327	hsa-miR-146b-5p	Luciferase reporter assay, qRT-PCR	25547151
MIRT462917	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT462917	hsa-miR-1247-3p	PAR-CLIP	26701625
MIRT462916	hsa-miR-1292-3p	PAR-CLIP	26701625
MIRT462916	hsa-miR-1292-3p	PAR-CLIP	26701625
MIRT462903	hsa-miR-1294	PAR-CLIP	26701625
MIRT462903	hsa-miR-1294	PAR-CLIP	26701625
MIRT462914	hsa-miR-1827	PAR-CLIP	26701625
MIRT462914	hsa-miR-1827	PAR-CLIP	26701625
MIRT370507	hsa-miR-1910-3p	PAR-CLIP	26701625
MIRT370507	hsa-miR-1910-3p	PAR-CLIP	26701625
MIRT462909	hsa-miR-2467-3p	PAR-CLIP	26701625
MIRT462909	hsa-miR-2467-3p	PAR-CLIP	26701625
MIRT462905	hsa-miR-3612	PAR-CLIP	26701625
MIRT462905	hsa-miR-3612	PAR-CLIP	26701625
MIRT462911	hsa-miR-377-5p	PAR-CLIP	26701625
MIRT462911	hsa-miR-377-5p	PAR-CLIP	26701625
MIRT462919	hsa-miR-4257	PAR-CLIP	26701625
MIRT462919	hsa-miR-4257	PAR-CLIP	26701625
MIRT462898	hsa-miR-4535	PAR-CLIP	26701625
MIRT462898	hsa-miR-4535	PAR-CLIP	26701625
MIRT462900	hsa-miR-455-3p	PAR-CLIP	26701625
MIRT462900	hsa-miR-455-3p	PAR-CLIP	26701625
MIRT462899	hsa-miR-4776-5p	PAR-CLIP	26701625
MIRT462899	hsa-miR-4776-5p	PAR-CLIP	26701625
MIRT462910	hsa-miR-6086	PAR-CLIP	26701625
MIRT462910	hsa-miR-6086	PAR-CLIP	26701625
MIRT462912	hsa-miR-6134	PAR-CLIP	26701625
MIRT462912	hsa-miR-6134	PAR-CLIP	26701625
MIRT462907	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT462907	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT462904	hsa-miR-650	PAR-CLIP	26701625
MIRT462904	hsa-miR-650	PAR-CLIP	26701625
MIRT370516	hsa-miR-6511a-5p	PAR-CLIP	26701625
MIRT370516	hsa-miR-6511a-5p	PAR-CLIP	26701625
MIRT462897	hsa-miR-6516-5p	PAR-CLIP	26701625
MIRT462897	hsa-miR-6516-5p	PAR-CLIP	26701625
MIRT462906	hsa-miR-711	PAR-CLIP	26701625
MIRT462906	hsa-miR-711	PAR-CLIP	26701625
MIRT462913	hsa-miR-7854-3p	PAR-CLIP	26701625
MIRT462913	hsa-miR-7854-3p	PAR-CLIP	26701625
MIRT462929	hsa-miR-34b-3p	PAR-CLIP	23592263
MIRT462928	hsa-miR-890	PAR-CLIP	23592263
MIRT370507	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT370516	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT370517	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT370519	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT370506	hsa-miR-940	PAR-CLIP	23592263
MIRT462927	hsa-miR-25-3p	PAR-CLIP	23592263
MIRT462926	hsa-miR-32-5p	PAR-CLIP	23592263
MIRT462925	hsa-miR-363-3p	PAR-CLIP	23592263
MIRT462924	hsa-miR-367-3p	PAR-CLIP	23592263
MIRT462923	hsa-miR-92a-3p	PAR-CLIP	23592263
MIRT462922	hsa-miR-92b-3p	PAR-CLIP	23592263
MIRT462921	hsa-miR-3614-5p	PAR-CLIP	23592263
MIRT462920	hsa-miR-6500-3p	PAR-CLIP	23592263
MIRT462919	hsa-miR-4257	PAR-CLIP	23592263
MIRT462918	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT462917	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT462916	hsa-miR-1292-3p	PAR-CLIP	23592263
MIRT462915	hsa-miR-4649-3p	PAR-CLIP	23592263
MIRT462914	hsa-miR-1827	PAR-CLIP	23592263
MIRT462913	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT462912	hsa-miR-6134	PAR-CLIP	23592263
MIRT462911	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT462910	hsa-miR-6086	PAR-CLIP	23592263
MIRT462909	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT462908	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT462907	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT462906	hsa-miR-711	PAR-CLIP	23592263
MIRT462905	hsa-miR-3612	PAR-CLIP	23592263
MIRT462904	hsa-miR-650	PAR-CLIP	23592263
MIRT462903	hsa-miR-1294	PAR-CLIP	23592263
MIRT462902	hsa-miR-7703	PAR-CLIP	23592263
MIRT462901	hsa-miR-4325	PAR-CLIP	23592263
MIRT462900	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT462899	hsa-miR-4776-5p	PAR-CLIP	23592263
MIRT462898	hsa-miR-4535	PAR-CLIP	23592263
MIRT462897	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT087424	hsa-miR-15a-5p	PAR-CLIP	22100165
MIRT087425	hsa-miR-15b-5p	PAR-CLIP	22100165
MIRT031450	hsa-miR-16-5p	PAR-CLIP	22100165
MIRT087426	hsa-miR-195-5p	PAR-CLIP	22100165
MIRT087428	hsa-miR-424-5p	PAR-CLIP	22100165
MIRT087429	hsa-miR-497-5p	PAR-CLIP	22100165
MIRT087435	hsa-miR-6838-5p	PAR-CLIP	22100165
MIRT444126	hsa-miR-503-5p	PAR-CLIP	22100165
MIRT444125	hsa-miR-646	PAR-CLIP	22100165
MIRT444124	hsa-miR-103b	PAR-CLIP	22100165
MIRT444123	hsa-miR-3661	PAR-CLIP	22100165
MIRT444122	hsa-miR-631	PAR-CLIP	22100165
MIRT087431	hsa-miR-4524a-5p	PAR-CLIP	22100165
MIRT087433	hsa-miR-4524b-5p	PAR-CLIP	22100165
MIRT444121	hsa-miR-376a-3p	PAR-CLIP	22100165
MIRT444120	hsa-miR-376b-3p	PAR-CLIP	22100165
MIRT444119	hsa-miR-192-5p	PAR-CLIP	22100165
MIRT444118	hsa-miR-215-5p	PAR-CLIP	22100165
MIRT1543316	hsa-miR-1262	CLIP-seq
MIRT1543317	hsa-miR-24	CLIP-seq
MIRT1543318	hsa-miR-25	CLIP-seq
MIRT1543319	hsa-miR-3122	CLIP-seq
MIRT1543320	hsa-miR-32	CLIP-seq
MIRT1543321	hsa-miR-34b	CLIP-seq
MIRT1543322	hsa-miR-3620	CLIP-seq
MIRT1543323	hsa-miR-3622a-3p	CLIP-seq
MIRT1543324	hsa-miR-3622b-3p	CLIP-seq
MIRT1543325	hsa-miR-363	CLIP-seq
MIRT1543326	hsa-miR-367	CLIP-seq
MIRT1543327	hsa-miR-3689a-3p	CLIP-seq
MIRT1543328	hsa-miR-3689c	CLIP-seq
MIRT1543329	hsa-miR-3913-5p	CLIP-seq
MIRT1543330	hsa-miR-3929	CLIP-seq
MIRT1543331	hsa-miR-4254	CLIP-seq
MIRT1543332	hsa-miR-4284	CLIP-seq
MIRT1543333	hsa-miR-4308	CLIP-seq
MIRT1543334	hsa-miR-4419b	CLIP-seq
MIRT1543335	hsa-miR-4455	CLIP-seq
MIRT1543336	hsa-miR-4478	CLIP-seq
MIRT1543337	hsa-miR-4633-3p	CLIP-seq
MIRT1543338	hsa-miR-4701-3p	CLIP-seq
MIRT1543339	hsa-miR-4728-5p	CLIP-seq
MIRT1543340	hsa-miR-485-5p	CLIP-seq
MIRT1543341	hsa-miR-508-5p	CLIP-seq
MIRT1543342	hsa-miR-520d-5p	CLIP-seq
MIRT1543343	hsa-miR-524-5p	CLIP-seq
MIRT1543344	hsa-miR-541	CLIP-seq
MIRT1543345	hsa-miR-544b	CLIP-seq
MIRT1543346	hsa-miR-583	CLIP-seq
MIRT1543347	hsa-miR-609	CLIP-seq
MIRT1543348	hsa-miR-654-5p	CLIP-seq
MIRT1543349	hsa-miR-661	CLIP-seq
MIRT1543350	hsa-miR-766	CLIP-seq
MIRT1543351	hsa-miR-92a	CLIP-seq
MIRT1543352	hsa-miR-92b	CLIP-seq
MIRT1543353	hsa-miR-1228	CLIP-seq
MIRT1543354	hsa-miR-1275	CLIP-seq
MIRT1543355	hsa-miR-3064-3p	CLIP-seq
MIRT1543321	hsa-miR-34b	CLIP-seq
MIRT1543335	hsa-miR-4455	CLIP-seq
MIRT1543356	hsa-miR-4488	CLIP-seq
MIRT1543357	hsa-miR-4665-5p	CLIP-seq
MIRT1543358	hsa-miR-4697-5p	CLIP-seq
MIRT1543347	hsa-miR-609	CLIP-seq
MIRT1543359	hsa-miR-877	CLIP-seq
MIRT1555870	hsa-miR-1267	CLIP-seq
MIRT1555871	hsa-miR-2053	CLIP-seq
MIRT1555872	hsa-miR-4506	CLIP-seq
MIRT1555873	hsa-miR-569	CLIP-seq
MIRT1555874	hsa-miR-670	CLIP-seq
MIRT1555875	hsa-miR-759	CLIP-seq
MIRT2163881	hsa-miR-1184	CLIP-seq
MIRT2163882	hsa-miR-1207-5p	CLIP-seq
MIRT1543316	hsa-miR-1262	CLIP-seq
MIRT2163883	hsa-miR-1289	CLIP-seq
MIRT2163884	hsa-miR-129-5p	CLIP-seq
MIRT2163885	hsa-miR-136	CLIP-seq
MIRT2163886	hsa-miR-147	CLIP-seq
MIRT2163887	hsa-miR-15a	CLIP-seq
MIRT2163888	hsa-miR-15b	CLIP-seq
MIRT2163889	hsa-miR-16	CLIP-seq
MIRT2163890	hsa-miR-1909	CLIP-seq
MIRT2163891	hsa-miR-1913	CLIP-seq
MIRT2163892	hsa-miR-195	CLIP-seq
MIRT2163893	hsa-miR-2113	CLIP-seq
MIRT2163894	hsa-miR-223	CLIP-seq
MIRT2163895	hsa-miR-296-3p	CLIP-seq
MIRT2163896	hsa-miR-30a	CLIP-seq
MIRT2163897	hsa-miR-30b	CLIP-seq
MIRT2163898	hsa-miR-30c	CLIP-seq
MIRT2163899	hsa-miR-30d	CLIP-seq
MIRT2163900	hsa-miR-30e	CLIP-seq
MIRT2163901	hsa-miR-3136-3p	CLIP-seq
MIRT2163902	hsa-miR-3173-3p	CLIP-seq
MIRT2163903	hsa-miR-3198	CLIP-seq
MIRT2163904	hsa-miR-3200-5p	CLIP-seq
MIRT2163905	hsa-miR-324-3p	CLIP-seq
MIRT2163906	hsa-miR-330-3p	CLIP-seq
MIRT2163907	hsa-miR-34a	CLIP-seq
MIRT1543321	hsa-miR-34b	CLIP-seq
MIRT2163908	hsa-miR-34c-5p	CLIP-seq
MIRT2163909	hsa-miR-3617	CLIP-seq
MIRT1543327	hsa-miR-3689a-3p	CLIP-seq
MIRT1543328	hsa-miR-3689c	CLIP-seq
MIRT2163910	hsa-miR-3714	CLIP-seq
MIRT1543330	hsa-miR-3929	CLIP-seq
MIRT2163911	hsa-miR-3936	CLIP-seq
MIRT2163912	hsa-miR-424	CLIP-seq
MIRT2163913	hsa-miR-4251	CLIP-seq
MIRT2163914	hsa-miR-4294	CLIP-seq
MIRT2163915	hsa-miR-4309	CLIP-seq
MIRT2163916	hsa-miR-4313	CLIP-seq
MIRT2163917	hsa-miR-4328	CLIP-seq
MIRT2163918	hsa-miR-4329	CLIP-seq
MIRT1543334	hsa-miR-4419b	CLIP-seq
MIRT2163919	hsa-miR-4421	CLIP-seq
MIRT2163920	hsa-miR-4444	CLIP-seq
MIRT1543335	hsa-miR-4455	CLIP-seq
MIRT2163921	hsa-miR-4461	CLIP-seq
MIRT2163922	hsa-miR-4474-3p	CLIP-seq
MIRT1543336	hsa-miR-4478	CLIP-seq
MIRT2163923	hsa-miR-449a	CLIP-seq
MIRT2163924	hsa-miR-449b	CLIP-seq
MIRT2163925	hsa-miR-4502	CLIP-seq
MIRT2163926	hsa-miR-4524	CLIP-seq
MIRT2163927	hsa-miR-4540	CLIP-seq
MIRT2163928	hsa-miR-4639-3p	CLIP-seq
MIRT2163929	hsa-miR-4676-5p	CLIP-seq
MIRT2163930	hsa-miR-4684-5p	CLIP-seq
MIRT2163931	hsa-miR-4690-3p	CLIP-seq
MIRT1543338	hsa-miR-4701-3p	CLIP-seq
MIRT2163932	hsa-miR-4717-3p	CLIP-seq
MIRT2163933	hsa-miR-4720-3p	CLIP-seq
MIRT2163934	hsa-miR-4721	CLIP-seq
MIRT1543339	hsa-miR-4728-5p	CLIP-seq
MIRT2163935	hsa-miR-4736	CLIP-seq
MIRT2163936	hsa-miR-4753-3p	CLIP-seq
MIRT2163937	hsa-miR-4763-3p	CLIP-seq
MIRT2163938	hsa-miR-4779	CLIP-seq
MIRT2163939	hsa-miR-4786-3p	CLIP-seq
MIRT2163940	hsa-miR-4803	CLIP-seq
MIRT2163941	hsa-miR-4804-3p	CLIP-seq
MIRT1543340	hsa-miR-485-5p	CLIP-seq
MIRT2163942	hsa-miR-488	CLIP-seq
MIRT2163943	hsa-miR-497	CLIP-seq
MIRT2163944	hsa-miR-548an	CLIP-seq
MIRT2163945	hsa-miR-556-3p	CLIP-seq
MIRT2163946	hsa-miR-575	CLIP-seq
MIRT2163947	hsa-miR-582-5p	CLIP-seq
MIRT2163948	hsa-miR-589	CLIP-seq
MIRT2163949	hsa-miR-599	CLIP-seq
MIRT2163950	hsa-miR-604	CLIP-seq
MIRT1543347	hsa-miR-609	CLIP-seq
MIRT2163951	hsa-miR-641	CLIP-seq
MIRT2163952	hsa-miR-644	CLIP-seq
MIRT2163953	hsa-miR-647	CLIP-seq
MIRT2163881	hsa-miR-1184	CLIP-seq
MIRT2383073	hsa-miR-1205	CLIP-seq
MIRT2383074	hsa-miR-1253	CLIP-seq
MIRT1543316	hsa-miR-1262	CLIP-seq
MIRT2383075	hsa-miR-1285	CLIP-seq
MIRT2163883	hsa-miR-1289	CLIP-seq
MIRT2383076	hsa-miR-1302	CLIP-seq
MIRT2163885	hsa-miR-136	CLIP-seq
MIRT2163887	hsa-miR-15a	CLIP-seq
MIRT2163888	hsa-miR-15b	CLIP-seq
MIRT2163889	hsa-miR-16	CLIP-seq
MIRT2383077	hsa-miR-185	CLIP-seq
MIRT2163892	hsa-miR-195	CLIP-seq
MIRT1543318	hsa-miR-25	CLIP-seq
MIRT2383078	hsa-miR-302a	CLIP-seq
MIRT2383079	hsa-miR-302b	CLIP-seq
MIRT2383080	hsa-miR-302c	CLIP-seq
MIRT2383081	hsa-miR-302d	CLIP-seq
MIRT2383082	hsa-miR-302e	CLIP-seq
MIRT2383083	hsa-miR-3148	CLIP-seq
MIRT2383084	hsa-miR-3153	CLIP-seq
MIRT2383085	hsa-miR-3154	CLIP-seq
MIRT2383086	hsa-miR-3158-5p	CLIP-seq
MIRT2383087	hsa-miR-3177-5p	CLIP-seq
MIRT2383088	hsa-miR-3179	CLIP-seq
MIRT2383089	hsa-miR-3180-5p	CLIP-seq
MIRT2383090	hsa-miR-3187-5p	CLIP-seq
MIRT2163903	hsa-miR-3198	CLIP-seq
MIRT1543320	hsa-miR-32	CLIP-seq
MIRT2383091	hsa-miR-335	CLIP-seq
MIRT1543321	hsa-miR-34b	CLIP-seq
MIRT2383092	hsa-miR-3607-5p	CLIP-seq
MIRT1543323	hsa-miR-3622a-3p	CLIP-seq
MIRT1543324	hsa-miR-3622b-3p	CLIP-seq
MIRT2383093	hsa-miR-3622b-5p	CLIP-seq
MIRT1543325	hsa-miR-363	CLIP-seq
MIRT1543326	hsa-miR-367	CLIP-seq
MIRT1543327	hsa-miR-3689a-3p	CLIP-seq
MIRT1543328	hsa-miR-3689c	CLIP-seq
MIRT2383094	hsa-miR-372	CLIP-seq
MIRT2383095	hsa-miR-373	CLIP-seq
MIRT1543330	hsa-miR-3929	CLIP-seq
MIRT2163911	hsa-miR-3936	CLIP-seq
MIRT2163912	hsa-miR-424	CLIP-seq
MIRT2163913	hsa-miR-4251	CLIP-seq
MIRT2163914	hsa-miR-4294	CLIP-seq
MIRT2383096	hsa-miR-4298	CLIP-seq
MIRT2383097	hsa-miR-4305	CLIP-seq
MIRT2383098	hsa-miR-4306	CLIP-seq
MIRT2163915	hsa-miR-4309	CLIP-seq
MIRT2163918	hsa-miR-4329	CLIP-seq
MIRT1543334	hsa-miR-4419b	CLIP-seq
MIRT1543335	hsa-miR-4455	CLIP-seq
MIRT2383099	hsa-miR-4468	CLIP-seq
MIRT1543336	hsa-miR-4478	CLIP-seq
MIRT2383100	hsa-miR-4501	CLIP-seq
MIRT2383101	hsa-miR-4504	CLIP-seq
MIRT2383102	hsa-miR-4519	CLIP-seq
MIRT2163926	hsa-miR-4524	CLIP-seq
MIRT2163928	hsa-miR-4639-3p	CLIP-seq
MIRT2383103	hsa-miR-4644	CLIP-seq
MIRT2383104	hsa-miR-4648	CLIP-seq
MIRT2383105	hsa-miR-4668-5p	CLIP-seq
MIRT1543338	hsa-miR-4701-3p	CLIP-seq
MIRT1543339	hsa-miR-4728-5p	CLIP-seq
MIRT2163940	hsa-miR-4803	CLIP-seq
MIRT1543340	hsa-miR-485-5p	CLIP-seq
MIRT2163943	hsa-miR-497	CLIP-seq
MIRT2383106	hsa-miR-503	CLIP-seq
MIRT1543341	hsa-miR-508-5p	CLIP-seq
MIRT2383107	hsa-miR-519a	CLIP-seq
MIRT2383108	hsa-miR-519b-3p	CLIP-seq
MIRT2383109	hsa-miR-519c-3p	CLIP-seq
MIRT2383110	hsa-miR-520a-3p	CLIP-seq
MIRT2383111	hsa-miR-520b	CLIP-seq
MIRT2383112	hsa-miR-520c-3p	CLIP-seq
MIRT2383113	hsa-miR-520d-3p	CLIP-seq
MIRT2383114	hsa-miR-520e	CLIP-seq
MIRT2383115	hsa-miR-548p	CLIP-seq
MIRT2383116	hsa-miR-570	CLIP-seq
MIRT2163947	hsa-miR-582-5p	CLIP-seq
MIRT2383117	hsa-miR-603	CLIP-seq
MIRT1543347	hsa-miR-609	CLIP-seq
MIRT2383118	hsa-miR-612	CLIP-seq
MIRT1543349	hsa-miR-661	CLIP-seq
MIRT1543350	hsa-miR-766	CLIP-seq
MIRT1543351	hsa-miR-92a	CLIP-seq
MIRT1543352	hsa-miR-92b	CLIP-seq
MIRT1543321	hsa-miR-34b	CLIP-seq
MIRT1543319	hsa-miR-3122	CLIP-seq
MIRT2464753	hsa-miR-3613-3p	CLIP-seq
MIRT1543323	hsa-miR-3622a-3p	CLIP-seq
MIRT1543324	hsa-miR-3622b-3p	CLIP-seq
MIRT1543327	hsa-miR-3689a-3p	CLIP-seq
MIRT1543328	hsa-miR-3689c	CLIP-seq
MIRT2464754	hsa-miR-371-5p	CLIP-seq
MIRT2464755	hsa-miR-371b-5p	CLIP-seq
MIRT1543329	hsa-miR-3913-5p	CLIP-seq
MIRT1543335	hsa-miR-4455	CLIP-seq
MIRT1543339	hsa-miR-4728-5p	CLIP-seq
MIRT1543344	hsa-miR-541	CLIP-seq
MIRT1543345	hsa-miR-544b	CLIP-seq
MIRT2163944	hsa-miR-548an	CLIP-seq
MIRT1543347	hsa-miR-609	CLIP-seq
MIRT1543348	hsa-miR-654-5p	CLIP-seq
MIRT2673533	hsa-miR-10a	CLIP-seq
MIRT2673534	hsa-miR-10b	CLIP-seq
MIRT1543319	hsa-miR-3122	CLIP-seq
MIRT1543321	hsa-miR-34b	CLIP-seq
MIRT1543323	hsa-miR-3622a-3p	CLIP-seq
MIRT1543324	hsa-miR-3622b-3p	CLIP-seq
MIRT1543327	hsa-miR-3689a-3p	CLIP-seq
MIRT1543328	hsa-miR-3689c	CLIP-seq
MIRT1543329	hsa-miR-3913-5p	CLIP-seq
MIRT1543330	hsa-miR-3929	CLIP-seq
MIRT1543334	hsa-miR-4419b	CLIP-seq
MIRT2163919	hsa-miR-4421	CLIP-seq
MIRT1543336	hsa-miR-4478	CLIP-seq
MIRT2163930	hsa-miR-4684-5p	CLIP-seq
MIRT1543339	hsa-miR-4728-5p	CLIP-seq
MIRT1543340	hsa-miR-485-5p	CLIP-seq
MIRT1543344	hsa-miR-541	CLIP-seq
MIRT1543345	hsa-miR-544b	CLIP-seq
MIRT2673535	hsa-miR-593	CLIP-seq
MIRT1543348	hsa-miR-654-5p	CLIP-seq
MIRT2673533	hsa-miR-10a	CLIP-seq
MIRT2673534	hsa-miR-10b	CLIP-seq
MIRT2163882	hsa-miR-1207-5p	CLIP-seq
MIRT1543354	hsa-miR-1275	CLIP-seq
MIRT2163890	hsa-miR-1909	CLIP-seq
MIRT1543319	hsa-miR-3122	CLIP-seq
MIRT1543321	hsa-miR-34b	CLIP-seq
MIRT1543323	hsa-miR-3622a-3p	CLIP-seq
MIRT1543324	hsa-miR-3622b-3p	CLIP-seq
MIRT1543327	hsa-miR-3689a-3p	CLIP-seq
MIRT1543328	hsa-miR-3689c	CLIP-seq
MIRT1543329	hsa-miR-3913-5p	CLIP-seq
MIRT1543330	hsa-miR-3929	CLIP-seq
MIRT2696423	hsa-miR-4264	CLIP-seq
MIRT1543334	hsa-miR-4419b	CLIP-seq
MIRT2163919	hsa-miR-4421	CLIP-seq
MIRT1543335	hsa-miR-4455	CLIP-seq
MIRT1543336	hsa-miR-4478	CLIP-seq
MIRT1543356	hsa-miR-4488	CLIP-seq
MIRT1543357	hsa-miR-4665-5p	CLIP-seq
MIRT2163930	hsa-miR-4684-5p	CLIP-seq
MIRT1543358	hsa-miR-4697-5p	CLIP-seq
MIRT1543339	hsa-miR-4728-5p	CLIP-seq
MIRT2163937	hsa-miR-4763-3p	CLIP-seq
MIRT2696424	hsa-miR-4797-3p	CLIP-seq
MIRT1543340	hsa-miR-485-5p	CLIP-seq
MIRT2696425	hsa-miR-486-3p	CLIP-seq
MIRT1543344	hsa-miR-541	CLIP-seq
MIRT1543345	hsa-miR-544b	CLIP-seq
MIRT2673535	hsa-miR-593	CLIP-seq
MIRT1543347	hsa-miR-609	CLIP-seq
MIRT1543348	hsa-miR-654-5p	CLIP-seq
MIRT1543359	hsa-miR-877	CLIP-seq

Show/Hide all(35)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004842	Function	Ubiquitin-protein transferase activity	IDA	22575959
GO:0005109	Function	Frizzled binding	IBA
GO:0005109	Function	Frizzled binding	IEA
GO:0005109	Function	Frizzled binding	IPI	22575959
GO:0005515	Function	Protein binding	IPI	22575959, 24165923, 29769720, 31073040, 32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	22575959
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IBA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IMP	22575959
GO:0008270	Function	Zinc ion binding	IEA
GO:0016020	Component	Membrane	IEA
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016567	Process	Protein ubiquitination	IDA	22575959
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030178	Process	Negative regulation of Wnt signaling pathway	IEA
GO:0038018	Process	Wnt receptor catabolic process	IBA
GO:0038018	Process	Wnt receptor catabolic process	IEA
GO:0038018	Process	Wnt receptor catabolic process	IMP	22575959
GO:0038018	Process	Wnt receptor catabolic process	TAS	24431302
GO:0046872	Function	Metal ion binding	IEA
GO:0060173	Process	Limb development	ISS
GO:0060828	Process	Regulation of canonical Wnt signaling pathway	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IBA
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	TAS	24431302
GO:0072089	Process	Stem cell proliferation	IEA
GO:0072089	Process	Stem cell proliferation	ISS
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IBA
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IMP	22575959
GO:2000050	Process	Regulation of non-canonical Wnt signaling pathway	IEA
GO:2000051	Process	Negative regulation of non-canonical Wnt signaling pathway	IMP	22575959
GO:2000095	Process	Regulation of Wnt signaling pathway, planar cell polarity pathway	IEA

MIM	HGNC	e!Ensembl
612062	18126	ENSG00000183579

Protein

UniProt ID

Q9ULT6

Protein name

E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING finger protein 203) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3)

Protein function

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical

PDB

8G4Y , 8XFP , 8XFS , 8XFT , 8Y69

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF18212	ZNRF_3_ecto	101 → 208	ZNRF-3 Ectodomain	Domain
PF17123	zf-RING_11	292 → 320	RING-like zinc finger	Domain

Sequence

MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAF
VEVVLFESSPSGDYTTYTTGLTGRFSRAGATLSAEGEIVQMHPLGLCNNNDEEDLYEYGW
VGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPV
VYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKI
KLKQRRSQNSMNRLAVQALEKMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKY
IDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRGRQQ
RVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYP
PLHLDHSLAAHRCGLEHRAYSPAHPFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYP
EQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCYHGHRSVCS
GYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYR
SRSPCRASEAGGSGSSGRGPALCFEGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVST
CSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCCEPQPSP
AGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCC
FYEEKQVARGGGGGSGCYTEDYSVSVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDL
GLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPPEEAGAV
RANFPSALQDTQESSTTATEAAGPRSHSADSSSPGA

Sequence length

936

Interactions

View interactions

	KEGG		Reactome
	Wnt signaling pathway		Regulation of FZD by ubiquitination

Show/Hide Unknown Diseases (8)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Acne	acne vulgaris	N/A	N/A	GWAS
Breast Cancer	Breast cancer	N/A	N/A	GWAS
Colorectal Cancer	Colorectal cancer	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Neurodevelopmental Disorders	complex neurodevelopmental disorder	N/A	N/A	GenCC
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS
Uterine Fibroids	Uterine fibroids	N/A	N/A	GWAS

Show/Hide Text Mining Associations (23)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adrenocortical Adenoma	Associate	33564960
Adrenocortical Carcinoma	Associate	25490274, 29581542, 29872083, 33513905, 33564960
Carcinogenesis	Associate	27661107, 33513905, 35040131
Carcinoma Hepatocellular	Associate	40264052
Carcinoma Squamous Cell	Associate	28901451
Cardiotoxicity	Associate	29247589
Chromosome Disorders	Associate	36631813
Diabetic Nephropathies	Associate	38189041
Disorder of Sex Development 46 XY	Associate	36631813
Esophageal Squamous Cell Carcinoma	Associate	30816445
Glaucoma Angle Closure	Associate	30348125
Leukoplakia	Associate	28901451
Microsatellite Instability	Associate	27661107
Neoplasm Metastasis	Associate	34716314
Neoplasms	Inhibit	25891077, 29497989
Neoplasms	Associate	27661107, 28901451, 29872083
Neuroendocrine Tumors	Associate	39536727
Osteoblastoma	Associate	24236197
Pancreatic Neoplasms	Associate	26098869
Pheochromocytoma	Associate	39536727
Prostatic Neoplasms	Associate	34716314
Prostatic Neoplasms Castration Resistant	Associate	34716314
Thyroid Cancer Papillary	Associate	25547151

ZNRF3 (zinc and ring finger 3)