Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
8407
Gene name Gene Name - the full gene name approved by the HGNC.
Transgelin 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TAGLN2
Synonyms (NCBI Gene) Gene synonyms aliases
HA1756
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q23.2
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT002788 hsa-miR-1-3p Luciferase reporter assay 20144220
MIRT002788 hsa-miR-1-3p Luciferase reporter assay 20144220
MIRT002788 hsa-miR-1-3p pSILAC 18668040
MIRT002788 hsa-miR-1-3p Microarray 15685193
MIRT002788 hsa-miR-1-3p Immunohistochemistry, Luciferase reporter assay, qRT-PCR, Western blot 21304530
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0002576 Process Platelet degranulation TAS
GO:0005515 Function Protein binding IPI 21577206, 32814053
GO:0005576 Component Extracellular region TAS
GO:0005829 Component Cytosol TAS
GO:0030855 Process Epithelial cell differentiation IDA 21492153
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
604634 11554 ENSG00000158710
Protein
UniProt ID P37802
Protein name Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-alpha homolog)
PDB 1WYM
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00307 CH 24 137 Calponin homology (CH) domain Domain
PF00402 Calponin 174 198 Calponin family repeat Repeat
Tissue specificity TISSUE SPECIFICITY: Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409}.
Sequence
Sequence length 199
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Platelet degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Papillary renal carcinoma Papillary Renal Cell Carcinoma rs5030823, rs2137087134, rs121913668, rs121913669, rs121913670, rs121913671, rs121913673, rs121913243, rs786202724 15108329
Renal carcinoma Renal Cell Carcinoma, Conventional (Clear Cell) Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Collecting Duct Carcinoma of the Kidney rs121913668, rs121913670, rs121913243, rs786202724 15108329
Unknown
Disease term Disease name Evidence References Source
Chromophobe carcinoma Chromophobe Renal Cell Carcinoma 15108329 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Abortion Spontaneous Associate 36750132
Acute Coronary Syndrome Associate 35683019
Adenocarcinoma of Lung Associate 19848416
Brain Neoplasms Associate 40247723
Breast Neoplasms Associate 26176734
Carcinogenesis Associate 29424888
Carcinoma Hepatocellular Stimulate 15756260
Carcinoma Hepatocellular Associate 16750200
Carcinoma Non Small Cell Lung Associate 30191639
Carcinoma Pancreatic Ductal Associate 28521289