Gene Gene information from NCBI Gene database.
Entrez ID 8407
Gene name Transgelin 2
Gene symbol TAGLN2
Synonyms (NCBI Gene)
HA1756
Chromosome 1
Chromosome location 1q23.2
Summary The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor
miRNA miRNA information provided by mirtarbase database.
783
miRTarBase ID miRNA Experiments Reference
MIRT002788 hsa-miR-1-3p Luciferase reporter assay 20144220
MIRT002788 hsa-miR-1-3p Luciferase reporter assay 20144220
MIRT002788 hsa-miR-1-3p pSILAC 18668040
MIRT002788 hsa-miR-1-3p Microarray 15685193
MIRT002788 hsa-miR-1-3p ImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot 21304530
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21577206, 28514442, 32814053, 33961781
GO:0005576 Component Extracellular region TAS
GO:0005829 Component Cytosol TAS
GO:0007015 Process Actin filament organization IBA
GO:0015629 Component Actin cytoskeleton IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604634 11554 ENSG00000158710
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P37802
Protein name Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-alpha homolog)
PDB 1WYM
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00307 CH 24 137 Calponin homology (CH) domain Domain
PF00402 Calponin 174 198 Calponin family repeat Repeat
Tissue specificity TISSUE SPECIFICITY: Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409}.
Sequence
Sequence length 199
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Platelet degranulation
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Gastric cancer Uncertain significance rs905936420 RCV005939243
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Abortion Spontaneous Associate 36750132
Acute Coronary Syndrome Associate 35683019
Adenocarcinoma of Lung Associate 19848416
Brain Neoplasms Associate 40247723
Breast Neoplasms Associate 26176734
Carcinogenesis Associate 29424888
Carcinoma Hepatocellular Stimulate 15756260
Carcinoma Hepatocellular Associate 16750200
Carcinoma Non Small Cell Lung Associate 30191639
Carcinoma Pancreatic Ductal Associate 28521289