Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	8405
Gene name	Speckle type BTB/POZ protein
Gene symbol	SPOP
Synonyms (NCBI Gene)	BTBD32NEDMACENEDMIDFNSDVS1NSDVS2TEF2
Chromosome	17
Chromosome location	17q21.33
Summary	This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein bin

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miRTarBase ID	miRNA	Experiments	Reference
MIRT644598	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT644597	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT644596	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT644595	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT644594	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT644593	hsa-miR-3182	HITS-CLIP	23824327
MIRT644592	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT644591	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT644590	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT644589	hsa-miR-548aj-5p	HITS-CLIP	23824327
MIRT644588	hsa-miR-548f-5p	HITS-CLIP	23824327
MIRT644587	hsa-miR-548g-5p	HITS-CLIP	23824327
MIRT644586	hsa-miR-548x-5p	HITS-CLIP	23824327
MIRT644585	hsa-miR-1468-3p	HITS-CLIP	23824327
MIRT644584	hsa-miR-623	HITS-CLIP	23824327
MIRT644583	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT644582	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT644581	hsa-miR-548aw	HITS-CLIP	23824327
MIRT644580	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT644579	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT644578	hsa-miR-544a	HITS-CLIP	23824327
MIRT644577	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT644576	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT644575	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT644574	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT644573	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT644572	hsa-miR-4282	HITS-CLIP	23824327
MIRT644571	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT644570	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT644569	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT644568	hsa-miR-3163	HITS-CLIP	23824327
MIRT644567	hsa-miR-1248	HITS-CLIP	23824327
MIRT644566	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT644565	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT644564	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT644563	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT644562	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT644561	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT644560	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT644559	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT644558	hsa-miR-3161	HITS-CLIP	23824327
MIRT644557	hsa-miR-4273	HITS-CLIP	23824327
MIRT644555	hsa-miR-7156-5p	HITS-CLIP	23824327
MIRT644556	hsa-miR-4677-5p	HITS-CLIP	23824327
MIRT644554	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT644553	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT644552	hsa-miR-599	HITS-CLIP	23824327
MIRT644551	hsa-miR-375	HITS-CLIP	23824327
MIRT644550	hsa-miR-6739-3p	HITS-CLIP	23824327
MIRT644549	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT644548	hsa-miR-605-5p	HITS-CLIP	23824327
MIRT644547	hsa-miR-4759	HITS-CLIP	23824327
MIRT644546	hsa-miR-3169	HITS-CLIP	23824327
MIRT644545	hsa-miR-8083	HITS-CLIP	23824327
MIRT644544	hsa-miR-188-5p	HITS-CLIP	23824327
MIRT644543	hsa-miR-6866-3p	HITS-CLIP	23824327
MIRT644541	hsa-miR-8063	HITS-CLIP	23824327
MIRT644542	hsa-miR-4698	HITS-CLIP	23824327
MIRT644540	hsa-miR-6792-5p	HITS-CLIP	23824327
MIRT644539	hsa-miR-3117-3p	HITS-CLIP	23824327
MIRT644538	hsa-miR-4503	HITS-CLIP	23824327
MIRT734550	hsa-miR-145-5p	ImmunofluorescenceqRT-PCR	32512734
MIRT644598	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT644597	hsa-miR-5088-3p	HITS-CLIP	23824327
MIRT644596	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT644595	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT644594	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT644593	hsa-miR-3182	HITS-CLIP	23824327
MIRT644592	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT644591	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT644590	hsa-miR-539-5p	HITS-CLIP	23824327
MIRT644589	hsa-miR-548aj-5p	HITS-CLIP	23824327
MIRT644588	hsa-miR-548f-5p	HITS-CLIP	23824327
MIRT644587	hsa-miR-548g-5p	HITS-CLIP	23824327
MIRT644586	hsa-miR-548x-5p	HITS-CLIP	23824327
MIRT644585	hsa-miR-1468-3p	HITS-CLIP	23824327
MIRT644584	hsa-miR-623	HITS-CLIP	23824327
MIRT644583	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT644582	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT644581	hsa-miR-548aw	HITS-CLIP	23824327
MIRT644580	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT644579	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT644578	hsa-miR-544a	HITS-CLIP	23824327
MIRT644577	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT644576	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT644575	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT644574	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT644573	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT644572	hsa-miR-4282	HITS-CLIP	23824327
MIRT644571	hsa-miR-3606-3p	HITS-CLIP	23824327
MIRT644570	hsa-miR-513a-3p	HITS-CLIP	23824327
MIRT644569	hsa-miR-513c-3p	HITS-CLIP	23824327
MIRT644568	hsa-miR-3163	HITS-CLIP	23824327
MIRT644567	hsa-miR-1248	HITS-CLIP	23824327
MIRT644566	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT644565	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT644564	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT644563	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT644562	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT644561	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT644560	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT644559	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT644558	hsa-miR-3161	HITS-CLIP	23824327
MIRT644557	hsa-miR-4273	HITS-CLIP	23824327
MIRT644555	hsa-miR-7156-5p	HITS-CLIP	23824327
MIRT644556	hsa-miR-4677-5p	HITS-CLIP	23824327
MIRT644554	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT644553	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT644552	hsa-miR-599	HITS-CLIP	23824327
MIRT644551	hsa-miR-375	HITS-CLIP	23824327
MIRT644550	hsa-miR-6739-3p	HITS-CLIP	23824327
MIRT644549	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT644548	hsa-miR-605-5p	HITS-CLIP	23824327
MIRT644547	hsa-miR-4759	HITS-CLIP	23824327
MIRT644546	hsa-miR-3169	HITS-CLIP	23824327
MIRT644545	hsa-miR-8083	HITS-CLIP	23824327
MIRT644544	hsa-miR-188-5p	HITS-CLIP	23824327
MIRT644543	hsa-miR-6866-3p	HITS-CLIP	23824327
MIRT644541	hsa-miR-8063	HITS-CLIP	23824327
MIRT644542	hsa-miR-4698	HITS-CLIP	23824327
MIRT644540	hsa-miR-6792-5p	HITS-CLIP	23824327
MIRT644539	hsa-miR-3117-3p	HITS-CLIP	23824327
MIRT644538	hsa-miR-4503	HITS-CLIP	23824327
MIRT1385206	hsa-miR-297	CLIP-seq
MIRT1385207	hsa-miR-3127-3p	CLIP-seq
MIRT1385208	hsa-miR-3149	CLIP-seq
MIRT1385209	hsa-miR-3154	CLIP-seq
MIRT1385210	hsa-miR-3173-3p	CLIP-seq
MIRT1385211	hsa-miR-3180-5p	CLIP-seq
MIRT1385212	hsa-miR-323-5p	CLIP-seq
MIRT1385213	hsa-miR-3671	CLIP-seq
MIRT1385214	hsa-miR-3691-3p	CLIP-seq
MIRT1385215	hsa-miR-4428	CLIP-seq
MIRT1385216	hsa-miR-4719	CLIP-seq
MIRT1385217	hsa-miR-5096	CLIP-seq
MIRT1385218	hsa-miR-513b	CLIP-seq
MIRT1385219	hsa-miR-520a-5p	CLIP-seq
MIRT1385220	hsa-miR-525-5p	CLIP-seq
MIRT1385221	hsa-miR-643	CLIP-seq
MIRT1385222	hsa-miR-876-3p	CLIP-seq
MIRT1385223	hsa-miR-1299	CLIP-seq
MIRT1385224	hsa-miR-1470	CLIP-seq
MIRT1385225	hsa-miR-3168	CLIP-seq
MIRT1385212	hsa-miR-323-5p	CLIP-seq
MIRT1385226	hsa-miR-338-5p	CLIP-seq
MIRT1385227	hsa-miR-3618	CLIP-seq
MIRT1385228	hsa-miR-3919	CLIP-seq
MIRT1385229	hsa-miR-3925-5p	CLIP-seq
MIRT1385230	hsa-miR-4294	CLIP-seq
MIRT1385231	hsa-miR-4456	CLIP-seq
MIRT1385232	hsa-miR-4667-3p	CLIP-seq
MIRT1385233	hsa-miR-4697-3p	CLIP-seq
MIRT1385234	hsa-miR-4709-5p	CLIP-seq
MIRT1385235	hsa-miR-4782-5p	CLIP-seq
MIRT1385236	hsa-miR-516b	CLIP-seq
MIRT1385237	hsa-miR-548ac	CLIP-seq
MIRT1385238	hsa-miR-548ae	CLIP-seq
MIRT1385239	hsa-miR-548aj	CLIP-seq
MIRT1385240	hsa-miR-548am	CLIP-seq
MIRT1385241	hsa-miR-548d-3p	CLIP-seq
MIRT1385242	hsa-miR-548x	CLIP-seq
MIRT1385243	hsa-miR-548z	CLIP-seq
MIRT1385244	hsa-miR-553	CLIP-seq
MIRT1385245	hsa-miR-579	CLIP-seq
MIRT1385246	hsa-miR-589	CLIP-seq
MIRT1385247	hsa-miR-604	CLIP-seq
MIRT1385248	hsa-miR-619	CLIP-seq
MIRT1385249	hsa-miR-642a	CLIP-seq
MIRT1385250	hsa-miR-647	CLIP-seq
MIRT1385251	hsa-miR-875-3p	CLIP-seq
MIRT1385222	hsa-miR-876-3p	CLIP-seq
MIRT1385252	hsa-miR-885-3p	CLIP-seq
MIRT1385253	hsa-miR-934	CLIP-seq
MIRT2115276	hsa-miR-1236	CLIP-seq
MIRT1385223	hsa-miR-1299	CLIP-seq
MIRT2115277	hsa-miR-3152-5p	CLIP-seq
MIRT1385211	hsa-miR-3180-5p	CLIP-seq
MIRT1385212	hsa-miR-323-5p	CLIP-seq
MIRT2115278	hsa-miR-3591-5p	CLIP-seq
MIRT2115279	hsa-miR-3614-5p	CLIP-seq
MIRT1385230	hsa-miR-4294	CLIP-seq
MIRT2115280	hsa-miR-4297	CLIP-seq
MIRT1385231	hsa-miR-4456	CLIP-seq
MIRT2115281	hsa-miR-4473	CLIP-seq
MIRT2115282	hsa-miR-4671-3p	CLIP-seq
MIRT1385233	hsa-miR-4697-3p	CLIP-seq
MIRT1385234	hsa-miR-4709-5p	CLIP-seq
MIRT2115283	hsa-miR-4774-3p	CLIP-seq
MIRT1385235	hsa-miR-4782-5p	CLIP-seq
MIRT1385236	hsa-miR-516b	CLIP-seq
MIRT1385244	hsa-miR-553	CLIP-seq
MIRT2115284	hsa-miR-600	CLIP-seq
MIRT1385247	hsa-miR-604	CLIP-seq
MIRT2115285	hsa-miR-616	CLIP-seq
MIRT1385248	hsa-miR-619	CLIP-seq
MIRT1385250	hsa-miR-647	CLIP-seq
MIRT1385251	hsa-miR-875-3p	CLIP-seq
MIRT1385222	hsa-miR-876-3p	CLIP-seq
MIRT1385252	hsa-miR-885-3p	CLIP-seq
MIRT2115286	hsa-miR-924	CLIP-seq
MIRT1385212	hsa-miR-323-5p	CLIP-seq
MIRT1385235	hsa-miR-4782-5p	CLIP-seq
MIRT2440775	hsa-miR-1305	CLIP-seq
MIRT2440776	hsa-miR-145	CLIP-seq
MIRT1385211	hsa-miR-3180-5p	CLIP-seq
MIRT2440777	hsa-miR-3591-3p	CLIP-seq
MIRT2440778	hsa-miR-421	CLIP-seq
MIRT2440779	hsa-miR-4328	CLIP-seq
MIRT2440775	hsa-miR-1305	CLIP-seq
MIRT2440776	hsa-miR-145	CLIP-seq
MIRT1385211	hsa-miR-3180-5p	CLIP-seq
MIRT2440777	hsa-miR-3591-3p	CLIP-seq
MIRT2440778	hsa-miR-421	CLIP-seq
MIRT2440779	hsa-miR-4328	CLIP-seq
MIRT1385211	hsa-miR-3180-5p	CLIP-seq
MIRT1385213	hsa-miR-3671	CLIP-seq
MIRT1385214	hsa-miR-3691-3p	CLIP-seq
MIRT1385216	hsa-miR-4719	CLIP-seq
MIRT1385217	hsa-miR-5096	CLIP-seq
MIRT1385218	hsa-miR-513b	CLIP-seq
MIRT1385219	hsa-miR-520a-5p	CLIP-seq
MIRT1385220	hsa-miR-525-5p	CLIP-seq
MIRT1385211	hsa-miR-3180-5p	CLIP-seq
MIRT1385213	hsa-miR-3671	CLIP-seq
MIRT1385219	hsa-miR-520a-5p	CLIP-seq
MIRT1385220	hsa-miR-525-5p	CLIP-seq

Show/Hide all (21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	IDA	14528312
GO:0005515	Function	Protein binding	IPI	16189514, 21573799, 21577200, 21988832, 22632832, 24656772, 28514442, 33961781, 35512704
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	22085717
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	9414087
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016607	Component	Nuclear speck	IEA
GO:0030162	Process	Regulation of proteolysis	IBA
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IDA	14528312, 22085717
GO:0031463	Component	Cul3-RING ubiquitin ligase complex	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IBA
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	11279055
GO:0042802	Function	Identical protein binding	IPI	22632832, 35512704
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	22085717, 32109420
GO:0140678	Function	Molecular function inhibitor activity	EXP	31624231

MIM	HGNC	e!Ensembl
602650	11254	ENSG00000121067

O43791

Protein name

Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1)

Protein function

Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination a

PDB

2CR2 , 3HQH , 3HQI , 3HQL , 3HQM , 3HSV , 3HTM , 3HU6 , 3IVB , 3IVQ , 3IVV , 4EOZ , 4HS2 , 4J8Z , 4O1V , 6F8F , 6F8G , 6I41 , 6I5P , 6I68 , 6I7A , 7D3D , 7KLZ , 7LIN , 7LIO , 7LIP , 7LIQ , 8DWS , 8DWT , 8DWU , 8DWV

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00917	MATH	38 → 163	MATH domain	Domain
PF00651	BTB	190 → 297	BTB/POZ domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:9414087}.

Sequence

MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG
ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ
RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK
VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR
VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE
NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ
CPFLGPPRKRLKQS

Sequence length

374

Interactions

View interactions

	KEGG		Reactome
	Hedgehog signaling pathway		Hedgehog 'on' state

198

Show/Hide Causal Diseases (6)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Nabais Sa-de Vries syndrome	Likely pathogenic	rs2543841231	RCV003335885
Neurodevelopmental disorder with microcephaly and dysmorphic facies	Likely pathogenic; Pathogenic	rs2143269972, rs2072157379, rs2072153488	RCV002249179 RCV001030767 RCV001030768
Neurodevelopmental disorder with relative macrocephaly and with or without cardiac or endocrine anomalies	Likely pathogenic; Pathogenic	rs2143268856, rs2072155694, rs968974699, rs2072168176	RCV003224990 RCV001030769 RCV001030771 RCV001030772
SPOP-related disorder	Likely pathogenic	rs2143295744	RCV003968584
SPOP-related neurodevelopmental condition	Likely pathogenic; Pathogenic	rs2143273650	RCV001788995
Squamous cell carcinoma of the head and neck	Likely pathogenic	rs2143295744	RCV005922740

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Malignant tumor of urinary bladder	-	rs2143295744	RCV005922719
Medulloblastoma	-	rs1057519971	RCV006254437
Neoplasm	Conflicting classifications of pathogenicity; -; Uncertain significance	rs193920894, rs1057519968, rs1057519972, rs1057519971, rs2072168946	RCV005229977 RCV005231557 RCV005231561 RCV005231559 RCV006274068
Prostate cancer	Uncertain significance; Conflicting classifications of pathogenicity	rs193921065, rs193920894, rs1057519966, rs2072151207, rs2072151354, rs2072151553, rs368288966, rs2072151628, rs2072151724, rs2072151984, rs2072151912, rs2072152068, rs2072152148, rs2072152226, rs2072152352 View all (129 more)	RCV000149021 RCV000149020 RCV001030831 RCV001030933 RCV001030951 RCV001030950 RCV001030949 RCV001030948 RCV001030833 RCV001030947 RCV001030946 RCV001030945 RCV001030944 RCV001030878 RCV001030943 RCV001030876 RCV001030877 RCV001030875 RCV001030874 RCV001030873 RCV001030872 RCV001030871 RCV001030870 RCV001030867 RCV001030869 RCV001030868 RCV001030866 RCV001030864 RCV001030865 RCV001030862 RCV001030863 RCV001030861 RCV001030860 RCV001030859 RCV001030858 RCV001030857 RCV001030856 RCV001030942 RCV001030855 RCV001030832 RCV001030941 RCV001030940 RCV001030939 RCV001030937 RCV001030938 RCV001030936 RCV001030935 RCV001030934 RCV001030932 RCV001030931 RCV001030930 RCV001030929 RCV001030928 RCV001030927 RCV001030926 RCV001030925 RCV001030924 RCV001030923 RCV001030922 RCV001030921 RCV001030920 RCV001030919 RCV001030854 RCV001030853 RCV001030852 RCV001030851 RCV001030849 RCV001030850 RCV001030918 RCV001030917 RCV001030916 RCV001030915 RCV001030914 RCV001030913 RCV001030912 RCV001030911 RCV001030910 RCV001030909 RCV001030908 RCV001030907 RCV001030906 RCV001030905 RCV001030904 RCV001030903 RCV001030990 RCV001030989 RCV001030988 RCV001030987 RCV001030986 RCV001030985 RCV001030984 RCV001030983 RCV001030982 RCV001030981 RCV001030980 RCV001030979 RCV001030978 RCV001030977 RCV001030976 RCV001030975 RCV001030974 RCV001030973 RCV001030972 RCV001030971 RCV001030970 RCV001030969 RCV001030968 RCV001030967 RCV001030902 RCV001030901 RCV001030900 RCV001030899 RCV001030898 RCV001030897 RCV001030896 RCV001030895 RCV001030894 RCV001030893 RCV001030892 RCV001030891 RCV001030890 RCV001030889 RCV001030888 RCV001030887 RCV001030886 RCV001030885 RCV001030884 RCV001030883 RCV001030882 RCV001030881 RCV001030880 RCV001030879 RCV001030966 RCV001030965 RCV001030964 RCV001030954 RCV001030953 RCV001030952 RCV001030959 RCV001030958 RCV001030957 RCV001030956 RCV001030955 RCV001030960 RCV001030840 RCV001030839 RCV001030838 RCV001030848 RCV001030834 RCV001030836 RCV001030835 RCV001030837 RCV001030842 RCV001030841 RCV001030843 RCV001030844 RCV001030845 RCV001030846 RCV001030847 RCV001030962 RCV001030963 RCV001030961

Show/Hide Text Mining Associations (49)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma	Associate	25274033, 29295717, 30720096, 32233522
Adenocarcinoma	Inhibit	37327205
Adenoma	Associate	27494611
Adenomatoid Tumor	Associate	28580939
Alzheimer Disease	Associate	32345668, 32568785
Brain Neoplasms	Associate	22688887
Breast Neoplasms	Associate	23559371, 30244836
Carcinogenesis	Associate	27780719, 28599312, 30237511, 33247697, 34987184, 35438056
Carcinogenesis	Inhibit	34509929
Carcinoma Hepatocellular	Associate	26156804, 37996058
Carcinoma Non Small Cell Lung	Associate	30407707, 35909476
Carcinoma Renal Cell	Associate	28718916, 33602681, 36474188
Carcinoma Renal Cell	Stimulate	30197334
Colorectal Neoplasms	Associate	26505385, 28599312
Congenital Abnormalities	Associate	32109420
Congenital thrombotic disease due to Protein C deficiency	Associate	23559371
Developmental Disabilities	Associate	32109420
Disease	Inhibit	24451148
Disease	Associate	37239316
Endometrial Neoplasms	Associate	23104009, 25766326, 28485815, 33602681, 36481790, 37904149
Facial Dysmorphism with Multiple Malformations	Associate	32109420
Glioblastoma	Associate	37382594
Glioma	Associate	22688887
Hemoglobinopathies	Associate	31126914
Hepatoblastoma	Associate	26156804
Hypertelorism	Associate	32109420
Intellectual Disability	Associate	32109420
Lymphatic Metastasis	Stimulate	36042498
Megalencephaly	Associate	32109420
Microcephaly	Associate	32109420
Neoplasm Metastasis	Associate	26156804, 28599312, 36042498
Neoplasms	Associate	22610119, 24451148, 24563616, 24969063, 24994784, 26505385, 26544944, 26657081, 27614073, 27626165, 30290146, 30595538, 31771591, 32109420, 32624276 View all (10 more)
Neoplasms	Inhibit	23559371, 24994784, 25274033, 26156804, 26344095, 26527005, 28599312, 28805820, 28810879, 29108467, 29996942, 30244836, 34509929, 37996058
Neoplasms Cystic Mucinous and Serous	Associate	23104009
Nonsyndromic Holoprosencephaly	Associate	27494611
Osteosarcoma	Inhibit	29461588
Personality Disorders	Associate	24994784
Plagiocephaly and X linked mental retardation	Associate	32109420
Prostate cancer familial	Associate	24796539
Prostatic Intraepithelial Neoplasia	Associate	26542946
Prostatic Neoplasms	Associate	22610119, 23559371, 24508459, 24563616, 24796539, 24969063, 24994784, 25201530, 25274033, 25278611, 26344095, 26344096, 26542946, 26544944, 27780719 View all (42 more)
Prostatic Neoplasms	Inhibit	24994784, 30237511
Prostatic Neoplasms Castration Resistant	Associate	30068710, 35220606, 37581614
Prostatitis	Associate	22610119, 24796539, 24994784, 26527005, 27780719, 34509929
Squamous Cell Carcinoma of Head and Neck	Associate	31298378
Stomach Neoplasms	Stimulate	35325318
Stomach Neoplasms	Associate	38246227
Uterine Cervical Neoplasms	Associate	35194034
Uterine Cervical Neoplasms	Stimulate	36042498

SPOP (speckle type BTB/POZ protein)