NCALD (neurocalcin delta)

Gene

• Entrez ID: 83988
• Gene name: Neurocalcin delta
• Gene symbol: NCALD
• Synonyms (NCBI Gene): -
• Chromosome: 8
• Chromosome location: 8q22.3
• Summary: This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; howeve

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT448662	hsa-miR-203a-3p	PAR-CLIP	22100165
MIRT448662	hsa-miR-203a-3p	PAR-CLIP	22100165
MIRT448661	hsa-miR-32-3p	PAR-CLIP	22100165
MIRT448660	hsa-miR-4635	PAR-CLIP	22100165
MIRT448659	hsa-miR-569	PAR-CLIP	22100165
MIRT448658	hsa-miR-4775	PAR-CLIP	22100165
MIRT448657	hsa-miR-6780a-3p	PAR-CLIP	22100165
MIRT448656	hsa-miR-2053	PAR-CLIP	22100165
MIRT448662	hsa-miR-203a-3p	PAR-CLIP	22100165
MIRT448662	hsa-miR-203a-3p	PAR-CLIP	22100165
MIRT448661	hsa-miR-32-3p	PAR-CLIP	22100165
MIRT448660	hsa-miR-4635	PAR-CLIP	22100165
MIRT448659	hsa-miR-569	PAR-CLIP	22100165
MIRT448658	hsa-miR-4775	PAR-CLIP	22100165
MIRT448657	hsa-miR-6780a-3p	PAR-CLIP	22100165
MIRT448656	hsa-miR-2053	PAR-CLIP	22100165
MIRT756397	hsa-miR-181d-5p	Luciferase reporter assay, Western blotting, qRT-PCR	35014676
MIRT1175593	hsa-miR-1271	CLIP-seq
MIRT1175594	hsa-miR-1273g	CLIP-seq
MIRT1175595	hsa-miR-182	CLIP-seq
MIRT1175596	hsa-miR-29a	CLIP-seq
MIRT1175597	hsa-miR-29b	CLIP-seq
MIRT1175598	hsa-miR-29c	CLIP-seq
MIRT1175599	hsa-miR-31	CLIP-seq
MIRT1175600	hsa-miR-4326	CLIP-seq
MIRT1175601	hsa-miR-4686	CLIP-seq
MIRT1175602	hsa-miR-4778-3p	CLIP-seq
MIRT1175603	hsa-miR-767-3p	CLIP-seq
MIRT1175604	hsa-miR-767-5p	CLIP-seq
MIRT1175605	hsa-miR-9	CLIP-seq
MIRT1175606	hsa-miR-96	CLIP-seq
MIRT1175607	hsa-miR-1263	CLIP-seq
MIRT1175593	hsa-miR-1271	CLIP-seq
MIRT1175594	hsa-miR-1273g	CLIP-seq
MIRT1175608	hsa-miR-1283	CLIP-seq
MIRT1175609	hsa-miR-1284	CLIP-seq
MIRT1175610	hsa-miR-1299	CLIP-seq
MIRT1175611	hsa-miR-181a	CLIP-seq
MIRT1175612	hsa-miR-181b	CLIP-seq
MIRT1175613	hsa-miR-181c	CLIP-seq
MIRT1175614	hsa-miR-181d	CLIP-seq
MIRT1175595	hsa-miR-182	CLIP-seq
MIRT1175615	hsa-miR-19a	CLIP-seq
MIRT1175616	hsa-miR-19b	CLIP-seq
MIRT1175617	hsa-miR-2113	CLIP-seq
MIRT1175618	hsa-miR-2467-3p	CLIP-seq
MIRT1175599	hsa-miR-31	CLIP-seq
MIRT1175619	hsa-miR-4262	CLIP-seq
MIRT1175620	hsa-miR-4304	CLIP-seq
MIRT1175600	hsa-miR-4326	CLIP-seq
MIRT1175621	hsa-miR-4436a	CLIP-seq
MIRT1175622	hsa-miR-4530	CLIP-seq
MIRT1175623	hsa-miR-4660	CLIP-seq
MIRT1175624	hsa-miR-4731-3p	CLIP-seq
MIRT1175602	hsa-miR-4778-3p	CLIP-seq
MIRT1175625	hsa-miR-4782-5p	CLIP-seq
MIRT1175626	hsa-miR-4801	CLIP-seq
MIRT1175627	hsa-miR-516b	CLIP-seq
MIRT1175628	hsa-miR-518a-5p	CLIP-seq
MIRT1175629	hsa-miR-527	CLIP-seq
MIRT1175630	hsa-miR-646	CLIP-seq
MIRT1175631	hsa-miR-875-3p	CLIP-seq
MIRT1175605	hsa-miR-9	CLIP-seq
MIRT1175632	hsa-miR-922	CLIP-seq
MIRT1175606	hsa-miR-96	CLIP-seq
MIRT1175593	hsa-miR-1271	CLIP-seq
MIRT1175594	hsa-miR-1273g	CLIP-seq
MIRT1175633	hsa-miR-141	CLIP-seq
MIRT1175595	hsa-miR-182	CLIP-seq
MIRT1175634	hsa-miR-200a	CLIP-seq
MIRT1175599	hsa-miR-31	CLIP-seq
MIRT1175635	hsa-miR-3187-3p	CLIP-seq
MIRT1175636	hsa-miR-3614-5p	CLIP-seq
MIRT1175600	hsa-miR-4326	CLIP-seq
MIRT1175637	hsa-miR-4435	CLIP-seq
MIRT1175638	hsa-miR-4529-5p	CLIP-seq
MIRT1175639	hsa-miR-4701-5p	CLIP-seq
MIRT1175602	hsa-miR-4778-3p	CLIP-seq
MIRT1175640	hsa-miR-4802-5p	CLIP-seq
MIRT1175641	hsa-miR-548s	CLIP-seq
MIRT1175642	hsa-miR-588	CLIP-seq
MIRT1175643	hsa-miR-765	CLIP-seq
MIRT1175605	hsa-miR-9	CLIP-seq
MIRT1175606	hsa-miR-96	CLIP-seq
MIRT1175610	hsa-miR-1299	CLIP-seq
MIRT2279955	hsa-miR-24	CLIP-seq
MIRT2279956	hsa-miR-4284	CLIP-seq
MIRT1175625	hsa-miR-4782-5p	CLIP-seq
MIRT1175627	hsa-miR-516b	CLIP-seq
MIRT1175631	hsa-miR-875-3p	CLIP-seq
MIRT2431502	hsa-miR-4267	CLIP-seq
MIRT2431503	hsa-miR-4797-5p	CLIP-seq
MIRT2431502	hsa-miR-4267	CLIP-seq
MIRT2431503	hsa-miR-4797-5p	CLIP-seq
MIRT1175610	hsa-miR-1299	CLIP-seq
MIRT2578453	hsa-miR-586	CLIP-seq
MIRT1175631	hsa-miR-875-3p	CLIP-seq
MIRT2578454	hsa-miR-1178	CLIP-seq
MIRT2578455	hsa-miR-1207-5p	CLIP-seq
MIRT2578456	hsa-miR-1243	CLIP-seq
MIRT2578457	hsa-miR-1272	CLIP-seq
MIRT2578458	hsa-miR-1289	CLIP-seq
MIRT1175610	hsa-miR-1299	CLIP-seq
MIRT2578459	hsa-miR-1304	CLIP-seq
MIRT2578460	hsa-miR-132	CLIP-seq
MIRT2578461	hsa-miR-1322	CLIP-seq
MIRT2578462	hsa-miR-1343	CLIP-seq
MIRT1175611	hsa-miR-181a	CLIP-seq
MIRT1175612	hsa-miR-181b	CLIP-seq
MIRT1175613	hsa-miR-181c	CLIP-seq
MIRT1175614	hsa-miR-181d	CLIP-seq
MIRT2578463	hsa-miR-1827	CLIP-seq
MIRT2578464	hsa-miR-1913	CLIP-seq
MIRT2578465	hsa-miR-2114	CLIP-seq
MIRT2578466	hsa-miR-212	CLIP-seq
MIRT2578467	hsa-miR-296-5p	CLIP-seq
MIRT2578468	hsa-miR-3147	CLIP-seq
MIRT2578469	hsa-miR-3149	CLIP-seq
MIRT2578470	hsa-miR-3163	CLIP-seq
MIRT2578471	hsa-miR-3182	CLIP-seq
MIRT1175635	hsa-miR-3187-3p	CLIP-seq
MIRT2578472	hsa-miR-3194-3p	CLIP-seq
MIRT2578473	hsa-miR-3198	CLIP-seq
MIRT2578474	hsa-miR-324-3p	CLIP-seq
MIRT2578475	hsa-miR-3622b-5p	CLIP-seq
MIRT2578476	hsa-miR-3667-3p	CLIP-seq
MIRT2578477	hsa-miR-3682-5p	CLIP-seq
MIRT2578478	hsa-miR-3688-3p	CLIP-seq
MIRT2578479	hsa-miR-3920	CLIP-seq
MIRT2578480	hsa-miR-3926	CLIP-seq
MIRT2578481	hsa-miR-410	CLIP-seq
MIRT2578482	hsa-miR-4259	CLIP-seq
MIRT1175619	hsa-miR-4262	CLIP-seq
MIRT2578483	hsa-miR-4290	CLIP-seq
MIRT2578484	hsa-miR-4294	CLIP-seq
MIRT2578485	hsa-miR-4309	CLIP-seq
MIRT2578486	hsa-miR-4314	CLIP-seq
MIRT2578487	hsa-miR-4320	CLIP-seq
MIRT2578488	hsa-miR-4427	CLIP-seq
MIRT2578489	hsa-miR-4428	CLIP-seq
MIRT2578490	hsa-miR-4434	CLIP-seq
MIRT1175637	hsa-miR-4435	CLIP-seq
MIRT2578491	hsa-miR-4473	CLIP-seq
MIRT2578492	hsa-miR-4516	CLIP-seq
MIRT2578493	hsa-miR-4528	CLIP-seq
MIRT2578494	hsa-miR-4533	CLIP-seq
MIRT2578495	hsa-miR-4641	CLIP-seq
MIRT2578496	hsa-miR-4646-5p	CLIP-seq
MIRT2578497	hsa-miR-4658	CLIP-seq
MIRT2578498	hsa-miR-4671-3p	CLIP-seq
MIRT2578499	hsa-miR-4688	CLIP-seq
MIRT2578500	hsa-miR-4698	CLIP-seq
MIRT1175639	hsa-miR-4701-5p	CLIP-seq
MIRT2578501	hsa-miR-4729	CLIP-seq
MIRT2578502	hsa-miR-4738-3p	CLIP-seq
MIRT2578503	hsa-miR-4747-5p	CLIP-seq
MIRT2578504	hsa-miR-4758-5p	CLIP-seq
MIRT2578505	hsa-miR-4763-3p	CLIP-seq
MIRT2578506	hsa-miR-4780	CLIP-seq
MIRT1175625	hsa-miR-4782-5p	CLIP-seq
MIRT2578507	hsa-miR-486-3p	CLIP-seq
MIRT2578508	hsa-miR-508-3p	CLIP-seq
MIRT2578509	hsa-miR-511	CLIP-seq
MIRT2578510	hsa-miR-512-3p	CLIP-seq
MIRT2578511	hsa-miR-513b	CLIP-seq
MIRT1175627	hsa-miR-516b	CLIP-seq
MIRT2578512	hsa-miR-520d-5p	CLIP-seq
MIRT2578513	hsa-miR-520f	CLIP-seq
MIRT2578514	hsa-miR-524-5p	CLIP-seq
MIRT2578515	hsa-miR-548ac	CLIP-seq
MIRT2578516	hsa-miR-548ae	CLIP-seq
MIRT2578517	hsa-miR-548aj	CLIP-seq
MIRT2578518	hsa-miR-548am	CLIP-seq
MIRT2578519	hsa-miR-548d-3p	CLIP-seq
MIRT1175641	hsa-miR-548s	CLIP-seq
MIRT2578520	hsa-miR-548x	CLIP-seq
MIRT2578521	hsa-miR-548z	CLIP-seq
MIRT2578522	hsa-miR-550b	CLIP-seq
MIRT2578523	hsa-miR-561	CLIP-seq
MIRT2578524	hsa-miR-579	CLIP-seq
MIRT2578453	hsa-miR-586	CLIP-seq
MIRT1175642	hsa-miR-588	CLIP-seq
MIRT2578525	hsa-miR-603	CLIP-seq
MIRT2578526	hsa-miR-623	CLIP-seq
MIRT2578527	hsa-miR-645	CLIP-seq
MIRT2578528	hsa-miR-664	CLIP-seq
MIRT1175631	hsa-miR-875-3p	CLIP-seq
MIRT2578454	hsa-miR-1178	CLIP-seq
MIRT2578455	hsa-miR-1207-5p	CLIP-seq
MIRT2578456	hsa-miR-1243	CLIP-seq
MIRT2578457	hsa-miR-1272	CLIP-seq
MIRT2578458	hsa-miR-1289	CLIP-seq
MIRT1175610	hsa-miR-1299	CLIP-seq
MIRT2578459	hsa-miR-1304	CLIP-seq
MIRT2578460	hsa-miR-132	CLIP-seq
MIRT2578461	hsa-miR-1322	CLIP-seq
MIRT2578462	hsa-miR-1343	CLIP-seq
MIRT2685888	hsa-miR-149	CLIP-seq
MIRT1175611	hsa-miR-181a	CLIP-seq
MIRT1175612	hsa-miR-181b	CLIP-seq
MIRT1175613	hsa-miR-181c	CLIP-seq
MIRT1175614	hsa-miR-181d	CLIP-seq
MIRT2578463	hsa-miR-1827	CLIP-seq
MIRT2578464	hsa-miR-1913	CLIP-seq
MIRT2578465	hsa-miR-2114	CLIP-seq
MIRT2578466	hsa-miR-212	CLIP-seq
MIRT2578467	hsa-miR-296-5p	CLIP-seq
MIRT2578468	hsa-miR-3147	CLIP-seq
MIRT2578469	hsa-miR-3149	CLIP-seq
MIRT2578470	hsa-miR-3163	CLIP-seq
MIRT2685889	hsa-miR-3180-5p	CLIP-seq
MIRT2578471	hsa-miR-3182	CLIP-seq
MIRT1175635	hsa-miR-3187-3p	CLIP-seq
MIRT2578472	hsa-miR-3194-3p	CLIP-seq
MIRT2578473	hsa-miR-3198	CLIP-seq
MIRT2578474	hsa-miR-324-3p	CLIP-seq
MIRT2578475	hsa-miR-3622b-5p	CLIP-seq
MIRT2685890	hsa-miR-3661	CLIP-seq
MIRT2578476	hsa-miR-3667-3p	CLIP-seq
MIRT2578477	hsa-miR-3682-5p	CLIP-seq
MIRT2578478	hsa-miR-3688-3p	CLIP-seq
MIRT2578479	hsa-miR-3920	CLIP-seq
MIRT2578480	hsa-miR-3926	CLIP-seq
MIRT2578481	hsa-miR-410	CLIP-seq
MIRT2578482	hsa-miR-4259	CLIP-seq
MIRT1175619	hsa-miR-4262	CLIP-seq
MIRT2578483	hsa-miR-4290	CLIP-seq
MIRT2578484	hsa-miR-4294	CLIP-seq
MIRT2578485	hsa-miR-4309	CLIP-seq
MIRT2578486	hsa-miR-4314	CLIP-seq
MIRT2578487	hsa-miR-4320	CLIP-seq
MIRT2578488	hsa-miR-4427	CLIP-seq
MIRT2578489	hsa-miR-4428	CLIP-seq
MIRT2578490	hsa-miR-4434	CLIP-seq
MIRT1175637	hsa-miR-4435	CLIP-seq
MIRT2578491	hsa-miR-4473	CLIP-seq
MIRT2578492	hsa-miR-4516	CLIP-seq
MIRT2578493	hsa-miR-4528	CLIP-seq
MIRT2578494	hsa-miR-4533	CLIP-seq
MIRT2578495	hsa-miR-4641	CLIP-seq
MIRT2578496	hsa-miR-4646-5p	CLIP-seq
MIRT2578497	hsa-miR-4658	CLIP-seq
MIRT2578498	hsa-miR-4671-3p	CLIP-seq
MIRT2578499	hsa-miR-4688	CLIP-seq
MIRT2578500	hsa-miR-4698	CLIP-seq
MIRT1175639	hsa-miR-4701-5p	CLIP-seq
MIRT2578501	hsa-miR-4729	CLIP-seq
MIRT2578502	hsa-miR-4738-3p	CLIP-seq
MIRT2578503	hsa-miR-4747-5p	CLIP-seq
MIRT2578504	hsa-miR-4758-5p	CLIP-seq
MIRT2578505	hsa-miR-4763-3p	CLIP-seq
MIRT2578506	hsa-miR-4780	CLIP-seq
MIRT1175625	hsa-miR-4782-5p	CLIP-seq
MIRT2578507	hsa-miR-486-3p	CLIP-seq
MIRT2578508	hsa-miR-508-3p	CLIP-seq
MIRT2578509	hsa-miR-511	CLIP-seq
MIRT2578510	hsa-miR-512-3p	CLIP-seq
MIRT2578511	hsa-miR-513b	CLIP-seq
MIRT1175627	hsa-miR-516b	CLIP-seq
MIRT2685891	hsa-miR-520a-5p	CLIP-seq
MIRT2578512	hsa-miR-520d-5p	CLIP-seq
MIRT2578513	hsa-miR-520f	CLIP-seq
MIRT2578514	hsa-miR-524-5p	CLIP-seq
MIRT2685892	hsa-miR-525-5p	CLIP-seq
MIRT2578515	hsa-miR-548ac	CLIP-seq
MIRT2578516	hsa-miR-548ae	CLIP-seq
MIRT2578517	hsa-miR-548aj	CLIP-seq
MIRT2578518	hsa-miR-548am	CLIP-seq
MIRT2578519	hsa-miR-548d-3p	CLIP-seq
MIRT1175641	hsa-miR-548s	CLIP-seq
MIRT2578520	hsa-miR-548x	CLIP-seq
MIRT2578521	hsa-miR-548z	CLIP-seq
MIRT2578522	hsa-miR-550b	CLIP-seq
MIRT2578523	hsa-miR-561	CLIP-seq
MIRT2578524	hsa-miR-579	CLIP-seq
MIRT2578453	hsa-miR-586	CLIP-seq
MIRT1175642	hsa-miR-588	CLIP-seq
MIRT2578525	hsa-miR-603	CLIP-seq
MIRT2578526	hsa-miR-623	CLIP-seq
MIRT2685893	hsa-miR-631	CLIP-seq
MIRT2578527	hsa-miR-645	CLIP-seq
MIRT2578528	hsa-miR-664	CLIP-seq
MIRT1175631	hsa-miR-875-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003073	Process	Regulation of systemic arterial blood pressure	IEA
GO:0003779	Function	Actin binding	IBA
GO:0003779	Function	Actin binding	IDA	11964161
GO:0003779	Function	Actin binding	IEA
GO:0005509	Function	Calcium ion binding	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 21516116, 25416956, 25519916, 28514442, 32296183, 32814053, 33961781
GO:0005829	Component	Cytosol	NAS	11964161
GO:0005829	Component	Cytosol	TAS
GO:0009966	Process	Regulation of signal transduction	IBA
GO:0015631	Function	Tubulin binding	IBA
GO:0015631	Function	Tubulin binding	IDA	11964161
GO:0016192	Process	Vesicle-mediated transport	NAS	11964161
GO:0019722	Process	Calcium-mediated signaling	IBA
GO:0019722	Process	Calcium-mediated signaling	IEA
GO:0030130	Component	Clathrin coat of trans-Golgi network vesicle	NAS	11964161
GO:0030276	Function	Clathrin binding	IDA	11964161
GO:0043014	Function	Alpha-tubulin binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 606722
• HGNC: 7655
• e!Ensembl: ENSG00000104490

Protein

• UniProt ID: P61601
• Protein name: Neurocalcin-delta
• Protein function: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13833	EF-hand_8	39 → 90	EF-hand domain pair	Domain
  PF13499	EF-hand_7	98 → 174	EF-hand domain pair	Domain
  PF13202	EF-hand_5	149 → 173	EF hand	Domain

• Tissue specificity: TISSUE SPECIFICITY: Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.
• Sequence:

  MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD
  ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE
  MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIV
  RLLQCDPSSAGQF

• Sequence length: 193

Pathways

KEGG:

Olfactory transduction

Reactome:

Activation of Ca-permeable Kainate Receptor

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Ovarian serous cystadenocarcinoma	Likely benign	rs13253373	RCV005927564

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Non Small Cell Lung	Associate	31109331
Carcinoma Ovarian Epithelial	Associate	32228639
Celiac Disease	Associate	26123480
Colorectal Neoplasms	Associate	35014676
Genetic Diseases Inborn	Associate	29241932
Leukemia Myeloid Acute	Associate	31109331
Muscular Dystrophy Duchenne	Associate	36935420
Neurocognitive Disorders	Associate	27862604
Ovarian Neoplasms	Associate	24961659, 31109331, 32228639, 34289901
Prostatic Neoplasms	Associate	26990456
Prostatic Neoplasms Castration Resistant	Associate	26990456
Triple Negative Breast Neoplasms	Associate	37770991