TATDN1 (TatD DNase domain containing 1)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
83940
Gene name Gene Name - the full gene name approved by the HGNC.
TatD DNase domain containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TATDN1
Synonyms (NCBI Gene) Gene synonyms aliases
CDA11
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8q24.13
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(7)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 15846844
GO:0005654 Component Nucleoplasm IDA
GO:0006259 Process DNA metabolic process IEA
GO:0008296 Function 3'-5'-exodeoxyribonuclease activity IBA 21873635
GO:0016888 Function Endodeoxyribonuclease activity, producing 5'-phosphomonoesters IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
619364 24220 ENSG00000147687
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q6P1N9
Protein name Deoxyribonuclease TATDN1 (EC 3.1.21.-) (Hepatocarcinoma high expression protein)
Protein function Deoxyribonuclease which catalyzes (in vitro) the decatenation of kinetoplast DNA, which are circular DNA catenated to each other, producing linear DNA molecules (By similarity). Plays an important role in chromosomal segregation and cell cycle p
PDB 2XIO , 8EFG
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01026 TatD_DNase 7 → 294 TatD related DNase Domain
Sequence
Sequence length 297
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Asthma Asthma 30787307 ClinVar, GWAS
Show/Hide Text Mining Associations (7)
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 21247443, 31298381
Carcinoma Hepatocellular Associate 31378885, 36894454
Carcinoma Non Small Cell Lung Associate 30481109
Neoplasm Invasiveness Stimulate 36894454
Neoplasm Metastasis Associate 31378885
Neoplasms Associate 30481109
Respiratory Tract Diseases Associate 34895312