TSPAN10 (tetraspanin 10)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
83882
Gene name Gene Name - the full gene name approved by the HGNC.
Tetraspanin 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TSPAN10
Synonyms (NCBI Gene) Gene synonyms aliases
OCSP
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q25.3
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(12)
miRTarBase ID miRNA Experiments Reference
MIRT574049 hsa-miR-6869-3p PAR-CLIP 20371350
MIRT574048 hsa-miR-3960 PAR-CLIP 20371350
MIRT574047 hsa-miR-8072 PAR-CLIP 20371350
MIRT574046 hsa-miR-4467 PAR-CLIP 20371350
MIRT574048 hsa-miR-3960 PAR-CLIP 26701625
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(7)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 28514442, 33961781
GO:0005886 Component Plasma membrane IBA
GO:0005886 Component Plasma membrane IEA
GO:0016020 Component Membrane IEA
GO:0019899 Function Enzyme binding IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9H1Z9
Protein name Tetraspanin-10 (Tspan-10) (Oculospanin)
Protein function Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell sur
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00335 Tetraspanin 76 → 318 Tetraspanin family Family
Tissue specificity TISSUE SPECIFICITY: Expressed in the eye, including iris, ciliary body, retinal pigment epithelium, but not lens (protein level). {ECO:0000269|PubMed:12107410}.
Sequence
Sequence length 355
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Myopia Myopia N/A N/A GWAS
Show/Hide Text Mining Associations (12)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Alzheimer Disease Associate 30535121, 36951251
Astigmatism Associate 30306274
Carcinoma Squamous Cell Associate 33960436
Diabetes Mellitus Type 2 Associate 30535121
Hereditary Breast and Ovarian Cancer Syndrome Associate 30535121
Macular Degeneration Associate 31995762
Myopia Associate 30306274, 30535121
Neoplasm Metastasis Associate 24485798
Neoplasms Associate 30535121
Neurodegenerative Diseases Associate 30535121