GRWD1 (glutamate rich WD repeat containing 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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83743 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Glutamate rich WD repeat containing 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GRWD1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CDW4, DIAR14, GRWD, RRB1, WDR28 |
Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19q13.33 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. [p |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | Q9BQ67 | |||||||||||||||||||||||||
Protein name | Glutamate-rich WD repeat-containing protein 1 | |||||||||||||||||||||||||
Protein function | Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness (PubMed:25990725). | |||||||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 446 | |||||||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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