GRWD1 (glutamate rich WD repeat containing 1)

Gene

• Entrez ID: 83743
• Gene name: Glutamate rich WD repeat containing 1
• Gene symbol: GRWD1
• Synonyms (NCBI Gene): CDW4, DIAR14, GRWD, RRB1, WDR28
• Chromosome: 19
• Chromosome location: 19q13.33
• Summary: This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. [p

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT028689	hsa-miR-27a-3p	Sequencing	20371350
MIRT028900	hsa-miR-26b-5p	Microarray	19088304
MIRT031380	hsa-miR-16-5p	Proteomics	18668040
MIRT044657	hsa-miR-320a	CLASH	23622248
MIRT633969	hsa-miR-514a-5p	HITS-CLIP	23824327
MIRT630083	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT630082	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT633968	hsa-miR-326	HITS-CLIP	23824327
MIRT633967	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT633966	hsa-miR-204-3p	HITS-CLIP	23824327
MIRT633965	hsa-miR-4646-5p	HITS-CLIP	23824327
MIRT633964	hsa-miR-3192-5p	HITS-CLIP	23824327
MIRT633963	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT633962	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT633961	hsa-miR-6089	HITS-CLIP	23824327
MIRT630076	hsa-miR-4284	HITS-CLIP	23824327
MIRT630075	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT633960	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT633959	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT633958	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT633957	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT633956	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT633955	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT633954	hsa-miR-4314	HITS-CLIP	23824327
MIRT630083	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT630082	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT630081	hsa-miR-4324	HITS-CLIP	23824327
MIRT630080	hsa-miR-544b	HITS-CLIP	23824327
MIRT630079	hsa-miR-1199-5p	HITS-CLIP	23824327
MIRT630078	hsa-miR-6751-3p	HITS-CLIP	23824327
MIRT630077	hsa-miR-4537	HITS-CLIP	23824327
MIRT630076	hsa-miR-4284	HITS-CLIP	23824327
MIRT630075	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630074	hsa-miR-1200	HITS-CLIP	23824327
MIRT572039	hsa-miR-3914	PAR-CLIP	20371350
MIRT572038	hsa-miR-1228-3p	PAR-CLIP	20371350
MIRT572037	hsa-miR-1306-5p	PAR-CLIP	20371350
MIRT572035	hsa-miR-3928-3p	PAR-CLIP	20371350
MIRT572036	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT572034	hsa-miR-7154-3p	PAR-CLIP	20371350
MIRT572033	hsa-miR-765	PAR-CLIP	20371350
MIRT572032	hsa-miR-6894-5p	PAR-CLIP	20371350
MIRT572031	hsa-miR-4443	PAR-CLIP	20371350
MIRT572030	hsa-miR-6515-5p	PAR-CLIP	20371350
MIRT572039	hsa-miR-3914	PAR-CLIP	20371350
MIRT572038	hsa-miR-1228-3p	PAR-CLIP	20371350
MIRT572037	hsa-miR-1306-5p	PAR-CLIP	20371350
MIRT572035	hsa-miR-3928-3p	PAR-CLIP	20371350
MIRT572036	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT572034	hsa-miR-7154-3p	PAR-CLIP	20371350
MIRT572033	hsa-miR-765	PAR-CLIP	20371350
MIRT572032	hsa-miR-6894-5p	PAR-CLIP	20371350
MIRT572031	hsa-miR-4443	PAR-CLIP	20371350
MIRT572030	hsa-miR-6515-5p	PAR-CLIP	20371350
MIRT562256	hsa-miR-5700	PAR-CLIP	20371350
MIRT562255	hsa-miR-4676-5p	PAR-CLIP	20371350
MIRT562254	hsa-miR-575	PAR-CLIP	20371350
MIRT562253	hsa-miR-2392	PAR-CLIP	20371350
MIRT562252	hsa-miR-4766-5p	PAR-CLIP	20371350
MIRT562251	hsa-miR-5681a	PAR-CLIP	20371350
MIRT562250	hsa-miR-6730-5p	PAR-CLIP	20371350
MIRT562249	hsa-miR-4786-3p	PAR-CLIP	20371350
MIRT562248	hsa-miR-539-5p	PAR-CLIP	20371350
MIRT562247	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT562246	hsa-miR-671-5p	PAR-CLIP	20371350
MIRT562245	hsa-miR-488-3p	PAR-CLIP	20371350
MIRT562244	hsa-miR-6079	PAR-CLIP	20371350
MIRT491149	hsa-miR-4756-3p	PAR-CLIP	23592263
MIRT491148	hsa-miR-4524a-3p	PAR-CLIP	23592263
MIRT491147	hsa-miR-1273f	PAR-CLIP	23592263
MIRT491146	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT491145	hsa-miR-4306	PAR-CLIP	23592263
MIRT491143	hsa-miR-4644	PAR-CLIP	23592263
MIRT491144	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT491142	hsa-miR-8085	PAR-CLIP	23592263
MIRT491141	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT491140	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT491139	hsa-miR-5698	PAR-CLIP	23592263
MIRT491138	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT491137	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT491135	hsa-miR-4525	PAR-CLIP	23592263
MIRT491136	hsa-miR-5010-5p	PAR-CLIP	23592263
MIRT491134	hsa-miR-1275	PAR-CLIP	23592263
MIRT491133	hsa-miR-4665-5p	PAR-CLIP	23592263
MIRT633969	hsa-miR-514a-5p	HITS-CLIP	23824327
MIRT630083	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT630082	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT633968	hsa-miR-326	HITS-CLIP	23824327
MIRT633967	hsa-miR-330-5p	HITS-CLIP	23824327
MIRT633966	hsa-miR-204-3p	HITS-CLIP	23824327
MIRT633965	hsa-miR-4646-5p	HITS-CLIP	23824327
MIRT633964	hsa-miR-3192-5p	HITS-CLIP	23824327
MIRT633963	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT633962	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT633961	hsa-miR-6089	HITS-CLIP	23824327
MIRT630076	hsa-miR-4284	HITS-CLIP	23824327
MIRT630075	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT633960	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT633959	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT633958	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT633957	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT633956	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT633955	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT633954	hsa-miR-4314	HITS-CLIP	23824327
MIRT630083	hsa-miR-4733-5p	HITS-CLIP	23824327
MIRT630082	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT630081	hsa-miR-4324	HITS-CLIP	23824327
MIRT630080	hsa-miR-544b	HITS-CLIP	23824327
MIRT630079	hsa-miR-1199-5p	HITS-CLIP	23824327
MIRT630078	hsa-miR-6751-3p	HITS-CLIP	23824327
MIRT630077	hsa-miR-4537	HITS-CLIP	23824327
MIRT630076	hsa-miR-4284	HITS-CLIP	23824327
MIRT630075	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT630074	hsa-miR-1200	HITS-CLIP	23824327
MIRT572039	hsa-miR-3914	PAR-CLIP	20371350
MIRT572038	hsa-miR-1228-3p	PAR-CLIP	20371350
MIRT572037	hsa-miR-1306-5p	PAR-CLIP	20371350
MIRT572035	hsa-miR-3928-3p	PAR-CLIP	20371350
MIRT572036	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT572034	hsa-miR-7154-3p	PAR-CLIP	20371350
MIRT572033	hsa-miR-765	PAR-CLIP	20371350
MIRT572032	hsa-miR-6894-5p	PAR-CLIP	20371350
MIRT572031	hsa-miR-4443	PAR-CLIP	20371350
MIRT572030	hsa-miR-6515-5p	PAR-CLIP	20371350
MIRT572039	hsa-miR-3914	PAR-CLIP	20371350
MIRT572038	hsa-miR-1228-3p	PAR-CLIP	20371350
MIRT572037	hsa-miR-1306-5p	PAR-CLIP	20371350
MIRT572035	hsa-miR-3928-3p	PAR-CLIP	20371350
MIRT572036	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT572034	hsa-miR-7154-3p	PAR-CLIP	20371350
MIRT572033	hsa-miR-765	PAR-CLIP	20371350
MIRT572032	hsa-miR-6894-5p	PAR-CLIP	20371350
MIRT572031	hsa-miR-4443	PAR-CLIP	20371350
MIRT572030	hsa-miR-6515-5p	PAR-CLIP	20371350
MIRT562256	hsa-miR-5700	PAR-CLIP	20371350
MIRT562255	hsa-miR-4676-5p	PAR-CLIP	20371350
MIRT562254	hsa-miR-575	PAR-CLIP	20371350
MIRT562253	hsa-miR-2392	PAR-CLIP	20371350
MIRT562252	hsa-miR-4766-5p	PAR-CLIP	20371350
MIRT562251	hsa-miR-5681a	PAR-CLIP	20371350
MIRT562250	hsa-miR-6730-5p	PAR-CLIP	20371350
MIRT562249	hsa-miR-4786-3p	PAR-CLIP	20371350
MIRT562248	hsa-miR-539-5p	PAR-CLIP	20371350
MIRT562247	hsa-miR-6828-5p	PAR-CLIP	20371350
MIRT562246	hsa-miR-671-5p	PAR-CLIP	20371350
MIRT562245	hsa-miR-488-3p	PAR-CLIP	20371350
MIRT562244	hsa-miR-6079	PAR-CLIP	20371350
MIRT491149	hsa-miR-4756-3p	PAR-CLIP	23592263
MIRT491148	hsa-miR-4524a-3p	PAR-CLIP	23592263
MIRT491147	hsa-miR-1273f	PAR-CLIP	23592263
MIRT491146	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT491145	hsa-miR-4306	PAR-CLIP	23592263
MIRT491143	hsa-miR-4644	PAR-CLIP	23592263
MIRT491144	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT491142	hsa-miR-8085	PAR-CLIP	23592263
MIRT491141	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT491140	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT491139	hsa-miR-5698	PAR-CLIP	23592263
MIRT491138	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT491137	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT491135	hsa-miR-4525	PAR-CLIP	23592263
MIRT491136	hsa-miR-5010-5p	PAR-CLIP	23592263
MIRT491134	hsa-miR-1275	PAR-CLIP	23592263
MIRT491133	hsa-miR-4665-5p	PAR-CLIP	23592263
MIRT1035591	hsa-miR-1233	CLIP-seq
MIRT1035592	hsa-miR-1243	CLIP-seq
MIRT1035593	hsa-miR-1252	CLIP-seq
MIRT1035594	hsa-miR-1273	CLIP-seq
MIRT1035595	hsa-miR-1273d	CLIP-seq
MIRT1035596	hsa-miR-1537	CLIP-seq
MIRT1035597	hsa-miR-1972	CLIP-seq
MIRT1035598	hsa-miR-217	CLIP-seq
MIRT1035599	hsa-miR-3123	CLIP-seq
MIRT1035600	hsa-miR-3127-3p	CLIP-seq
MIRT1035601	hsa-miR-3140-5p	CLIP-seq
MIRT1035602	hsa-miR-3180	CLIP-seq
MIRT1035603	hsa-miR-3180-3p	CLIP-seq
MIRT1035604	hsa-miR-3192	CLIP-seq
MIRT1035605	hsa-miR-3196	CLIP-seq
MIRT1035606	hsa-miR-3613-3p	CLIP-seq
MIRT1035607	hsa-miR-3689a-3p	CLIP-seq
MIRT1035608	hsa-miR-3689c	CLIP-seq
MIRT1035609	hsa-miR-371-5p	CLIP-seq
MIRT1035610	hsa-miR-371b-5p	CLIP-seq
MIRT1035611	hsa-miR-383	CLIP-seq
MIRT1035612	hsa-miR-3925-5p	CLIP-seq
MIRT1035613	hsa-miR-421	CLIP-seq
MIRT1035614	hsa-miR-4264	CLIP-seq
MIRT1035615	hsa-miR-4328	CLIP-seq
MIRT1035616	hsa-miR-4418	CLIP-seq
MIRT1035617	hsa-miR-4459	CLIP-seq
MIRT1035618	hsa-miR-4476	CLIP-seq
MIRT1035619	hsa-miR-4486	CLIP-seq
MIRT1035620	hsa-miR-4533	CLIP-seq
MIRT1035621	hsa-miR-4649-5p	CLIP-seq
MIRT1035622	hsa-miR-4685-5p	CLIP-seq
MIRT1035623	hsa-miR-4690-3p	CLIP-seq
MIRT1035624	hsa-miR-4695-5p	CLIP-seq
MIRT1035625	hsa-miR-4704-3p	CLIP-seq
MIRT1035626	hsa-miR-4709-5p	CLIP-seq
MIRT1035627	hsa-miR-4710	CLIP-seq
MIRT1035628	hsa-miR-4717-5p	CLIP-seq
MIRT1035629	hsa-miR-4733-3p	CLIP-seq
MIRT1035630	hsa-miR-4777-5p	CLIP-seq
MIRT1035631	hsa-miR-4792	CLIP-seq
MIRT1035632	hsa-miR-4793-3p	CLIP-seq
MIRT1035633	hsa-miR-4797-3p	CLIP-seq
MIRT1035634	hsa-miR-4797-5p	CLIP-seq
MIRT1035635	hsa-miR-495	CLIP-seq
MIRT1035636	hsa-miR-505	CLIP-seq
MIRT1035637	hsa-miR-508-5p	CLIP-seq
MIRT1035638	hsa-miR-509-3-5p	CLIP-seq
MIRT1035639	hsa-miR-509-5p	CLIP-seq
MIRT1035640	hsa-miR-518d-5p	CLIP-seq
MIRT1035641	hsa-miR-519b-5p	CLIP-seq
MIRT1035642	hsa-miR-519c-5p	CLIP-seq
MIRT1035643	hsa-miR-520c-5p	CLIP-seq
MIRT1035644	hsa-miR-526a	CLIP-seq
MIRT1035645	hsa-miR-548a-3p	CLIP-seq
MIRT1035646	hsa-miR-548ae	CLIP-seq
MIRT1035647	hsa-miR-548aj	CLIP-seq
MIRT1035648	hsa-miR-548am	CLIP-seq
MIRT1035649	hsa-miR-548e	CLIP-seq
MIRT1035650	hsa-miR-548f	CLIP-seq
MIRT1035651	hsa-miR-548x	CLIP-seq
MIRT1035652	hsa-miR-598	CLIP-seq
MIRT1035653	hsa-miR-600	CLIP-seq
MIRT1035654	hsa-miR-658	CLIP-seq
MIRT1035655	hsa-miR-661	CLIP-seq
MIRT1035656	hsa-miR-665	CLIP-seq
MIRT1035657	hsa-miR-766	CLIP-seq
MIRT1035658	hsa-miR-9	CLIP-seq
MIRT1035659	hsa-miR-939	CLIP-seq
MIRT1035593	hsa-miR-1252	CLIP-seq
MIRT1035595	hsa-miR-1273d	CLIP-seq
MIRT1035599	hsa-miR-3123	CLIP-seq
MIRT1035600	hsa-miR-3127-3p	CLIP-seq
MIRT2007058	hsa-miR-3160-3p	CLIP-seq
MIRT1035604	hsa-miR-3192	CLIP-seq
MIRT2007059	hsa-miR-34b	CLIP-seq
MIRT2007060	hsa-miR-3660	CLIP-seq
MIRT1035613	hsa-miR-421	CLIP-seq
MIRT1035614	hsa-miR-4264	CLIP-seq
MIRT1035615	hsa-miR-4328	CLIP-seq
MIRT1035617	hsa-miR-4459	CLIP-seq
MIRT1035618	hsa-miR-4476	CLIP-seq
MIRT2007061	hsa-miR-4487	CLIP-seq
MIRT2007062	hsa-miR-4499	CLIP-seq
MIRT2007063	hsa-miR-4526	CLIP-seq
MIRT1035620	hsa-miR-4533	CLIP-seq
MIRT1035622	hsa-miR-4685-5p	CLIP-seq
MIRT1035624	hsa-miR-4695-5p	CLIP-seq
MIRT1035625	hsa-miR-4704-3p	CLIP-seq
MIRT1035626	hsa-miR-4709-5p	CLIP-seq
MIRT1035633	hsa-miR-4797-3p	CLIP-seq
MIRT1035636	hsa-miR-505	CLIP-seq
MIRT2007064	hsa-miR-558	CLIP-seq
MIRT2007065	hsa-miR-619	CLIP-seq
MIRT1035654	hsa-miR-658	CLIP-seq
MIRT1035656	hsa-miR-665	CLIP-seq
MIRT1035659	hsa-miR-939	CLIP-seq
MIRT1035594	hsa-miR-1273	CLIP-seq
MIRT2239588	hsa-miR-137	CLIP-seq
MIRT1035597	hsa-miR-1972	CLIP-seq
MIRT1035598	hsa-miR-217	CLIP-seq
MIRT1035606	hsa-miR-3613-3p	CLIP-seq
MIRT1035615	hsa-miR-4328	CLIP-seq
MIRT1035616	hsa-miR-4418	CLIP-seq
MIRT2239589	hsa-miR-4455	CLIP-seq
MIRT1035619	hsa-miR-4486	CLIP-seq
MIRT2239590	hsa-miR-451b	CLIP-seq
MIRT1035621	hsa-miR-4649-5p	CLIP-seq
MIRT1035628	hsa-miR-4717-5p	CLIP-seq
MIRT2239591	hsa-miR-4731-3p	CLIP-seq
MIRT1035629	hsa-miR-4733-3p	CLIP-seq
MIRT1035632	hsa-miR-4793-3p	CLIP-seq
MIRT2239592	hsa-miR-4801	CLIP-seq
MIRT1035637	hsa-miR-508-5p	CLIP-seq
MIRT1035638	hsa-miR-509-3-5p	CLIP-seq
MIRT1035639	hsa-miR-509-5p	CLIP-seq
MIRT1035645	hsa-miR-548a-3p	CLIP-seq
MIRT1035646	hsa-miR-548ae	CLIP-seq
MIRT1035647	hsa-miR-548aj	CLIP-seq
MIRT1035648	hsa-miR-548am	CLIP-seq
MIRT1035649	hsa-miR-548e	CLIP-seq
MIRT1035650	hsa-miR-548f	CLIP-seq
MIRT1035651	hsa-miR-548x	CLIP-seq
MIRT1035652	hsa-miR-598	CLIP-seq
MIRT2007065	hsa-miR-619	CLIP-seq
MIRT1035655	hsa-miR-661	CLIP-seq
MIRT1035657	hsa-miR-766	CLIP-seq
MIRT1035591	hsa-miR-1233	CLIP-seq
MIRT2239588	hsa-miR-137	CLIP-seq
MIRT2450824	hsa-miR-3664-3p	CLIP-seq
MIRT2450825	hsa-miR-4433	CLIP-seq
MIRT1035617	hsa-miR-4459	CLIP-seq
MIRT2450826	hsa-miR-4732-3p	CLIP-seq
MIRT2450827	hsa-miR-4768-3p	CLIP-seq
MIRT2450828	hsa-miR-767-3p	CLIP-seq
MIRT1035591	hsa-miR-1233	CLIP-seq
MIRT2239588	hsa-miR-137	CLIP-seq
MIRT2450824	hsa-miR-3664-3p	CLIP-seq
MIRT2450825	hsa-miR-4433	CLIP-seq
MIRT1035617	hsa-miR-4459	CLIP-seq
MIRT2450826	hsa-miR-4732-3p	CLIP-seq
MIRT2450827	hsa-miR-4768-3p	CLIP-seq
MIRT2450828	hsa-miR-767-3p	CLIP-seq
MIRT1035594	hsa-miR-1273	CLIP-seq
MIRT1035598	hsa-miR-217	CLIP-seq
MIRT1035604	hsa-miR-3192	CLIP-seq
MIRT1035606	hsa-miR-3613-3p	CLIP-seq
MIRT1035609	hsa-miR-371-5p	CLIP-seq
MIRT1035610	hsa-miR-371b-5p	CLIP-seq
MIRT1035616	hsa-miR-4418	CLIP-seq
MIRT2543316	hsa-miR-4432	CLIP-seq
MIRT1035619	hsa-miR-4486	CLIP-seq
MIRT1035621	hsa-miR-4649-5p	CLIP-seq
MIRT1035632	hsa-miR-4793-3p	CLIP-seq
MIRT1035635	hsa-miR-495	CLIP-seq
MIRT1035637	hsa-miR-508-5p	CLIP-seq
MIRT1035638	hsa-miR-509-3-5p	CLIP-seq
MIRT1035639	hsa-miR-509-5p	CLIP-seq
MIRT2007065	hsa-miR-619	CLIP-seq
MIRT1035655	hsa-miR-661	CLIP-seq
MIRT1035657	hsa-miR-766	CLIP-seq
MIRT1035594	hsa-miR-1273	CLIP-seq
MIRT1035598	hsa-miR-217	CLIP-seq
MIRT1035604	hsa-miR-3192	CLIP-seq
MIRT1035606	hsa-miR-3613-3p	CLIP-seq
MIRT1035609	hsa-miR-371-5p	CLIP-seq
MIRT1035610	hsa-miR-371b-5p	CLIP-seq
MIRT1035616	hsa-miR-4418	CLIP-seq
MIRT2543316	hsa-miR-4432	CLIP-seq
MIRT1035619	hsa-miR-4486	CLIP-seq
MIRT1035621	hsa-miR-4649-5p	CLIP-seq
MIRT1035632	hsa-miR-4793-3p	CLIP-seq
MIRT1035635	hsa-miR-495	CLIP-seq
MIRT1035637	hsa-miR-508-5p	CLIP-seq
MIRT1035638	hsa-miR-509-3-5p	CLIP-seq
MIRT1035639	hsa-miR-509-5p	CLIP-seq
MIRT2007065	hsa-miR-619	CLIP-seq
MIRT1035655	hsa-miR-661	CLIP-seq
MIRT1035657	hsa-miR-766	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003682	Function	Chromatin binding	IDA	25990725
GO:0003688	Function	DNA replication origin binding	IDA	25990725
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	17041588, 18832067, 23349634, 25990725
GO:0005634	Component	Nucleus	IDA	25990725
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA
GO:0005730	Component	Nucleolus	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006260	Process	DNA replication	IEA
GO:0006260	Process	DNA replication	IMP	25990725
GO:0006334	Process	Nucleosome assembly	IDA	25990725
GO:0006334	Process	Nucleosome assembly	IMP	27552915
GO:0006337	Process	Nucleosome disassembly	IMP	27552915
GO:0032991	Component	Protein-containing complex	IDA	23349634
GO:0042254	Process	Ribosome biogenesis	IBA
GO:0042393	Function	Histone binding	IDA	25990725

Other IDs

• MIM: 610597
• HGNC: 21270
• e!Ensembl: ENSG00000105447

Protein

• UniProt ID: Q9BQ67
• Protein name: Glutamate-rich WD repeat-containing protein 1
• Protein function: Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness (PubMed:25990725).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12265	CAF1C_H4-bd	44 → 112	Histone-binding protein RBBP4 or subunit C of CAF1 complex	Family
  PF00400	WD40	252 → 290	WD domain, G-beta repeat	Repeat
  PF00400	WD40	298 → 336	WD domain, G-beta repeat	Repeat
  PF00400	WD40	343 → 382	WD domain, G-beta repeat	Repeat

• Sequence:

  MAARKGRRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRA
  QTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSE
  GSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFAL
  RRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIH
  LWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACM
  LTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVE
  WHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKEL
  HWHPQCPGLLVSTALSGFTIFRTISV

• Sequence length: 446

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
GRWD1-related disorder	Likely benign; Benign	rs371143886, rs138248385, rs765448597, rs200635717, rs370055883, rs766182030, rs138505126, rs144509270, rs201385782, rs184556377, rs747893188	RCV003906963 RCV003911808 RCV003937355 RCV003941463 RCV003934459 RCV003914380 RCV003931417 RCV003936968 RCV003944413 RCV003932049 RCV003971791
Prostate cancer	Uncertain significance	rs147327994	RCV000149314

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Renal Cell	Associate	34616846
Cerebral Infarction	Associate	39290696
Chromosomal Instability	Associate	34616846
Diabetes Mellitus Type 2	Associate	35601016
Kidney Diseases	Associate	34616846
Neoplasms	Associate	34616846
Precancerous Conditions	Associate	34616846
Urinary Bladder Neoplasms	Associate	33287884
Uterine Cervical Neoplasms	Associate	32806782