ITCH (itchy E3 ubiquitin protein ligase)

Gene

• Entrez ID: 83737
• Gene name: Itchy E3 ubiquitin protein ligase
• Gene symbol: ITCH
• Synonyms (NCBI Gene): ADMFD, AIF4, AIP4, NAPP1
• Chromosome: 20
• Chromosome location: 20q11.22
• Summary: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs587776592	->A	Pathogenic	Coding sequence variant, non coding transcript variant, frameshift variant, 5 prime UTR variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT000372	hsa-miR-106b-5p	Luciferase reporter assay, Western blot	19096009
MIRT000372	hsa-miR-106b-5p	Luciferase reporter assay	19074548
MIRT000372	hsa-miR-106b-5p	Microarray	17242205
MIRT042842	hsa-miR-324-3p	CLASH	23622248
MIRT475091	hsa-miR-543	PAR-CLIP	23592263
MIRT475090	hsa-miR-128-3p	PAR-CLIP	23592263
MIRT475089	hsa-miR-216a-3p	PAR-CLIP	23592263
MIRT475088	hsa-miR-3681-3p	PAR-CLIP	23592263
MIRT475087	hsa-miR-1252-5p	PAR-CLIP	23592263
MIRT475086	hsa-miR-8068	PAR-CLIP	23592263
MIRT475085	hsa-miR-3143	PAR-CLIP	23592263
MIRT475084	hsa-miR-27a-3p	PAR-CLIP	23592263
MIRT475083	hsa-miR-27b-3p	PAR-CLIP	23592263
MIRT475082	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT000372	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440427	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440426	hsa-miR-485-5p	HITS-CLIP	24374217
MIRT440424	hsa-miR-127-5p	HITS-CLIP	24374217
MIRT440425	hsa-miR-541-5p	HITS-CLIP	24374217
MIRT000372	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT727420	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727418	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727419	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727417	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440427	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440426	hsa-miR-485-5p	HITS-CLIP	24374217
MIRT440424	hsa-miR-127-5p	HITS-CLIP	24374217
MIRT440425	hsa-miR-541-5p	HITS-CLIP	24374217
MIRT000372	hsa-miR-106b-5p	Immunoprecipitaion, Luciferase reporter assay, qRT-PCR	26621835
MIRT475091	hsa-miR-543	PAR-CLIP	23592263
MIRT475090	hsa-miR-128-3p	PAR-CLIP	23592263
MIRT475089	hsa-miR-216a-3p	PAR-CLIP	23592263
MIRT475088	hsa-miR-3681-3p	PAR-CLIP	23592263
MIRT475087	hsa-miR-1252-5p	PAR-CLIP	23592263
MIRT475086	hsa-miR-8068	PAR-CLIP	23592263
MIRT475085	hsa-miR-3143	PAR-CLIP	23592263
MIRT475084	hsa-miR-27a-3p	PAR-CLIP	23592263
MIRT475083	hsa-miR-27b-3p	PAR-CLIP	23592263
MIRT475082	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT1073184	hsa-miR-106a	CLIP-seq
MIRT1073185	hsa-miR-106b	CLIP-seq
MIRT1073186	hsa-miR-1179	CLIP-seq
MIRT1073187	hsa-miR-1182	CLIP-seq
MIRT1073188	hsa-miR-1184	CLIP-seq
MIRT1073189	hsa-miR-1205	CLIP-seq
MIRT1073190	hsa-miR-1243	CLIP-seq
MIRT1073191	hsa-miR-1252	CLIP-seq
MIRT1073192	hsa-miR-1255a	CLIP-seq
MIRT1073193	hsa-miR-1255b	CLIP-seq
MIRT1073194	hsa-miR-1264	CLIP-seq
MIRT1073195	hsa-miR-1265	CLIP-seq
MIRT1073196	hsa-miR-1266	CLIP-seq
MIRT1073197	hsa-miR-1273g	CLIP-seq
MIRT1073198	hsa-miR-128	CLIP-seq
MIRT1073199	hsa-miR-146a	CLIP-seq
MIRT1073200	hsa-miR-146b-5p	CLIP-seq
MIRT1073201	hsa-miR-150	CLIP-seq
MIRT1073202	hsa-miR-17	CLIP-seq
MIRT1073203	hsa-miR-1914	CLIP-seq
MIRT1073204	hsa-miR-193a-5p	CLIP-seq
MIRT1073205	hsa-miR-20a	CLIP-seq
MIRT1073206	hsa-miR-20b	CLIP-seq
MIRT1073207	hsa-miR-214	CLIP-seq
MIRT1073208	hsa-miR-2392	CLIP-seq
MIRT1073209	hsa-miR-25	CLIP-seq
MIRT1073210	hsa-miR-27a	CLIP-seq
MIRT1073211	hsa-miR-27b	CLIP-seq
MIRT1073212	hsa-miR-298	CLIP-seq
MIRT1073213	hsa-miR-3158-3p	CLIP-seq
MIRT1073214	hsa-miR-3158-5p	CLIP-seq
MIRT1073215	hsa-miR-3163	CLIP-seq
MIRT1073216	hsa-miR-3180-5p	CLIP-seq
MIRT1073217	hsa-miR-3192	CLIP-seq
MIRT1073218	hsa-miR-32	CLIP-seq
MIRT1073219	hsa-miR-338-5p	CLIP-seq
MIRT1073220	hsa-miR-340	CLIP-seq
MIRT1073221	hsa-miR-346	CLIP-seq
MIRT1073222	hsa-miR-34b	CLIP-seq
MIRT1073223	hsa-miR-3609	CLIP-seq
MIRT1073224	hsa-miR-361-3p	CLIP-seq
MIRT1073225	hsa-miR-3617	CLIP-seq
MIRT1073226	hsa-miR-3619-3p	CLIP-seq
MIRT1073227	hsa-miR-3619-5p	CLIP-seq
MIRT1073228	hsa-miR-363	CLIP-seq
MIRT1073229	hsa-miR-3646	CLIP-seq
MIRT1073230	hsa-miR-3654	CLIP-seq
MIRT1073231	hsa-miR-3658	CLIP-seq
MIRT1073232	hsa-miR-367	CLIP-seq
MIRT1073233	hsa-miR-3686	CLIP-seq
MIRT1073234	hsa-miR-3919	CLIP-seq
MIRT1073235	hsa-miR-3925-5p	CLIP-seq
MIRT1073236	hsa-miR-3973	CLIP-seq
MIRT1073237	hsa-miR-3976	CLIP-seq
MIRT1073238	hsa-miR-409-5p	CLIP-seq
MIRT1073239	hsa-miR-421	CLIP-seq
MIRT1073240	hsa-miR-4275	CLIP-seq
MIRT1073241	hsa-miR-4282	CLIP-seq
MIRT1073242	hsa-miR-4288	CLIP-seq
MIRT1073243	hsa-miR-431	CLIP-seq
MIRT1073244	hsa-miR-4328	CLIP-seq
MIRT1073245	hsa-miR-4330	CLIP-seq
MIRT1073246	hsa-miR-4422	CLIP-seq
MIRT1073247	hsa-miR-4423-5p	CLIP-seq
MIRT1073248	hsa-miR-4436b-3p	CLIP-seq
MIRT1073249	hsa-miR-4452	CLIP-seq
MIRT1073250	hsa-miR-4514	CLIP-seq
MIRT1073251	hsa-miR-4518	CLIP-seq
MIRT1073252	hsa-miR-4520b-3p	CLIP-seq
MIRT1073253	hsa-miR-4529-3p	CLIP-seq
MIRT1073254	hsa-miR-4535	CLIP-seq
MIRT1073255	hsa-miR-4645-5p	CLIP-seq
MIRT1073256	hsa-miR-4662a-3p	CLIP-seq
MIRT1073257	hsa-miR-4666-5p	CLIP-seq
MIRT1073258	hsa-miR-4673	CLIP-seq
MIRT1073259	hsa-miR-4692	CLIP-seq
MIRT1073260	hsa-miR-4699-3p	CLIP-seq
MIRT1073261	hsa-miR-4701-5p	CLIP-seq
MIRT1073262	hsa-miR-4709-5p	CLIP-seq
MIRT1073263	hsa-miR-4712-3p	CLIP-seq
MIRT1073264	hsa-miR-4721	CLIP-seq
MIRT1073265	hsa-miR-4729	CLIP-seq
MIRT1073266	hsa-miR-4734	CLIP-seq
MIRT1073267	hsa-miR-4742-3p	CLIP-seq
MIRT1073268	hsa-miR-4760-5p	CLIP-seq
MIRT1073269	hsa-miR-4761-3p	CLIP-seq
MIRT1073270	hsa-miR-4764-5p	CLIP-seq
MIRT1073271	hsa-miR-4775	CLIP-seq
MIRT1073272	hsa-miR-4776-5p	CLIP-seq
MIRT1073273	hsa-miR-4778-5p	CLIP-seq
MIRT1073274	hsa-miR-4781-3p	CLIP-seq
MIRT1073275	hsa-miR-4796-3p	CLIP-seq
MIRT1073276	hsa-miR-4799-5p	CLIP-seq
MIRT1073277	hsa-miR-519a	CLIP-seq
MIRT1073278	hsa-miR-519b-3p	CLIP-seq
MIRT1073279	hsa-miR-519c-3p	CLIP-seq
MIRT1073280	hsa-miR-519d	CLIP-seq
MIRT1073281	hsa-miR-520a-5p	CLIP-seq
MIRT1073282	hsa-miR-520g	CLIP-seq
MIRT1073283	hsa-miR-520h	CLIP-seq
MIRT1073284	hsa-miR-525-5p	CLIP-seq
MIRT1073285	hsa-miR-548ah	CLIP-seq
MIRT1073286	hsa-miR-548c-3p	CLIP-seq
MIRT1073287	hsa-miR-568	CLIP-seq
MIRT1073288	hsa-miR-577	CLIP-seq
MIRT1073289	hsa-miR-579	CLIP-seq
MIRT1073290	hsa-miR-580	CLIP-seq
MIRT1073291	hsa-miR-587	CLIP-seq
MIRT1073292	hsa-miR-588	CLIP-seq
MIRT1073293	hsa-miR-589	CLIP-seq
MIRT1073294	hsa-miR-599	CLIP-seq
MIRT1073295	hsa-miR-617	CLIP-seq
MIRT1073296	hsa-miR-632	CLIP-seq
MIRT1073297	hsa-miR-641	CLIP-seq
MIRT1073298	hsa-miR-643	CLIP-seq
MIRT1073299	hsa-miR-645	CLIP-seq
MIRT1073300	hsa-miR-651	CLIP-seq
MIRT1073301	hsa-miR-654-3p	CLIP-seq
MIRT1073302	hsa-miR-663b	CLIP-seq
MIRT1073303	hsa-miR-670	CLIP-seq
MIRT1073304	hsa-miR-7	CLIP-seq
MIRT1073305	hsa-miR-761	CLIP-seq
MIRT1073306	hsa-miR-92a	CLIP-seq
MIRT1073307	hsa-miR-92b	CLIP-seq
MIRT1073308	hsa-miR-93	CLIP-seq
MIRT1073309	hsa-miR-935	CLIP-seq
MIRT1073310	hsa-miR-940	CLIP-seq
MIRT1073187	hsa-miR-1182	CLIP-seq
MIRT1550244	hsa-miR-154	CLIP-seq
MIRT1550245	hsa-miR-300	CLIP-seq
MIRT1550246	hsa-miR-381	CLIP-seq
MIRT1073247	hsa-miR-4423-5p	CLIP-seq
MIRT1073274	hsa-miR-4781-3p	CLIP-seq
MIRT1073184	hsa-miR-106a	CLIP-seq
MIRT1073185	hsa-miR-106b	CLIP-seq
MIRT2018017	hsa-miR-1206	CLIP-seq
MIRT2018018	hsa-miR-1224-3p	CLIP-seq
MIRT1073191	hsa-miR-1252	CLIP-seq
MIRT2018019	hsa-miR-1260	CLIP-seq
MIRT2018020	hsa-miR-1260b	CLIP-seq
MIRT1073194	hsa-miR-1264	CLIP-seq
MIRT2018021	hsa-miR-1280	CLIP-seq
MIRT2018022	hsa-miR-1343	CLIP-seq
MIRT2018023	hsa-miR-145	CLIP-seq
MIRT1073202	hsa-miR-17	CLIP-seq
MIRT2018024	hsa-miR-2053	CLIP-seq
MIRT1073205	hsa-miR-20a	CLIP-seq
MIRT1073206	hsa-miR-20b	CLIP-seq
MIRT1073207	hsa-miR-214	CLIP-seq
MIRT2018025	hsa-miR-216b	CLIP-seq
MIRT2018026	hsa-miR-3152-5p	CLIP-seq
MIRT1073213	hsa-miR-3158-3p	CLIP-seq
MIRT1073215	hsa-miR-3163	CLIP-seq
MIRT2018027	hsa-miR-3166	CLIP-seq
MIRT1073219	hsa-miR-338-5p	CLIP-seq
MIRT1073220	hsa-miR-340	CLIP-seq
MIRT1073225	hsa-miR-3617	CLIP-seq
MIRT1073227	hsa-miR-3619-5p	CLIP-seq
MIRT1073237	hsa-miR-3976	CLIP-seq
MIRT2018028	hsa-miR-410	CLIP-seq
MIRT1073239	hsa-miR-421	CLIP-seq
MIRT2018029	hsa-miR-4259	CLIP-seq
MIRT2018030	hsa-miR-4287	CLIP-seq
MIRT1073243	hsa-miR-431	CLIP-seq
MIRT2018031	hsa-miR-433	CLIP-seq
MIRT2018032	hsa-miR-4469	CLIP-seq
MIRT2018033	hsa-miR-4509	CLIP-seq
MIRT2018034	hsa-miR-450b-3p	CLIP-seq
MIRT2018035	hsa-miR-4645-3p	CLIP-seq
MIRT2018036	hsa-miR-4662a-5p	CLIP-seq
MIRT2018037	hsa-miR-4685-3p	CLIP-seq
MIRT2018038	hsa-miR-4691-3p	CLIP-seq
MIRT2018039	hsa-miR-4703-3p	CLIP-seq
MIRT1073262	hsa-miR-4709-5p	CLIP-seq
MIRT2018040	hsa-miR-4713-3p	CLIP-seq
MIRT2018041	hsa-miR-4715-5p	CLIP-seq
MIRT1073264	hsa-miR-4721	CLIP-seq
MIRT2018042	hsa-miR-4740-3p	CLIP-seq
MIRT1073271	hsa-miR-4775	CLIP-seq
MIRT1073280	hsa-miR-519d	CLIP-seq
MIRT2018043	hsa-miR-532-3p	CLIP-seq
MIRT1073286	hsa-miR-548c-3p	CLIP-seq
MIRT1073289	hsa-miR-579	CLIP-seq
MIRT1073290	hsa-miR-580	CLIP-seq
MIRT2018044	hsa-miR-606	CLIP-seq
MIRT1073295	hsa-miR-617	CLIP-seq
MIRT1073297	hsa-miR-641	CLIP-seq
MIRT1073301	hsa-miR-654-3p	CLIP-seq
MIRT2018045	hsa-miR-656	CLIP-seq
MIRT2018046	hsa-miR-665	CLIP-seq
MIRT1073304	hsa-miR-7	CLIP-seq
MIRT1073305	hsa-miR-761	CLIP-seq
MIRT2018047	hsa-miR-769-3p	CLIP-seq
MIRT2018048	hsa-miR-887	CLIP-seq
MIRT2018049	hsa-miR-924	CLIP-seq
MIRT1073308	hsa-miR-93	CLIP-seq
MIRT2249818	hsa-miR-105	CLIP-seq
MIRT1073184	hsa-miR-106a	CLIP-seq
MIRT1073185	hsa-miR-106b	CLIP-seq
MIRT2249819	hsa-miR-1178	CLIP-seq
MIRT1073186	hsa-miR-1179	CLIP-seq
MIRT1073188	hsa-miR-1184	CLIP-seq
MIRT1073189	hsa-miR-1205	CLIP-seq
MIRT2018017	hsa-miR-1206	CLIP-seq
MIRT2018018	hsa-miR-1224-3p	CLIP-seq
MIRT2249820	hsa-miR-1226	CLIP-seq
MIRT2249821	hsa-miR-1246	CLIP-seq
MIRT2249822	hsa-miR-125a-5p	CLIP-seq
MIRT2249823	hsa-miR-125b	CLIP-seq
MIRT2018019	hsa-miR-1260	CLIP-seq
MIRT2018020	hsa-miR-1260b	CLIP-seq
MIRT1073194	hsa-miR-1264	CLIP-seq
MIRT2249824	hsa-miR-1276	CLIP-seq
MIRT2018021	hsa-miR-1280	CLIP-seq
MIRT2249825	hsa-miR-1299	CLIP-seq
MIRT2249826	hsa-miR-1321	CLIP-seq
MIRT2249827	hsa-miR-144	CLIP-seq
MIRT2018023	hsa-miR-145	CLIP-seq
MIRT1073199	hsa-miR-146a	CLIP-seq
MIRT1073200	hsa-miR-146b-5p	CLIP-seq
MIRT1073201	hsa-miR-150	CLIP-seq
MIRT1073202	hsa-miR-17	CLIP-seq
MIRT2249828	hsa-miR-186	CLIP-seq
MIRT2249829	hsa-miR-1915	CLIP-seq
MIRT2018024	hsa-miR-2053	CLIP-seq
MIRT1073205	hsa-miR-20a	CLIP-seq
MIRT1073206	hsa-miR-20b	CLIP-seq
MIRT1073207	hsa-miR-214	CLIP-seq
MIRT2018025	hsa-miR-216b	CLIP-seq
MIRT2249830	hsa-miR-2355-5p	CLIP-seq
MIRT1073209	hsa-miR-25	CLIP-seq
MIRT1073212	hsa-miR-298	CLIP-seq
MIRT1550245	hsa-miR-300	CLIP-seq
MIRT2249831	hsa-miR-3121-3p	CLIP-seq
MIRT2249832	hsa-miR-3133	CLIP-seq
MIRT2249833	hsa-miR-3140-5p	CLIP-seq
MIRT2249834	hsa-miR-3145-3p	CLIP-seq
MIRT2249835	hsa-miR-3145-5p	CLIP-seq
MIRT2249836	hsa-miR-3148	CLIP-seq
MIRT2249837	hsa-miR-3150a-5p	CLIP-seq
MIRT2249838	hsa-miR-3150b-5p	CLIP-seq
MIRT2018026	hsa-miR-3152-5p	CLIP-seq
MIRT1073213	hsa-miR-3158-3p	CLIP-seq
MIRT1073214	hsa-miR-3158-5p	CLIP-seq
MIRT2249839	hsa-miR-3159	CLIP-seq
MIRT2249840	hsa-miR-3162-5p	CLIP-seq
MIRT1073215	hsa-miR-3163	CLIP-seq
MIRT2018027	hsa-miR-3166	CLIP-seq
MIRT2249841	hsa-miR-3171	CLIP-seq
MIRT1073216	hsa-miR-3180-5p	CLIP-seq
MIRT1073217	hsa-miR-3192	CLIP-seq
MIRT1073218	hsa-miR-32	CLIP-seq
MIRT2249842	hsa-miR-330-3p	CLIP-seq
MIRT2249843	hsa-miR-345	CLIP-seq
MIRT1073221	hsa-miR-346	CLIP-seq
MIRT1073222	hsa-miR-34b	CLIP-seq
MIRT2249844	hsa-miR-3529	CLIP-seq
MIRT2249845	hsa-miR-3607-3p	CLIP-seq
MIRT1073224	hsa-miR-361-3p	CLIP-seq
MIRT1073225	hsa-miR-3617	CLIP-seq
MIRT1073227	hsa-miR-3619-5p	CLIP-seq
MIRT1073228	hsa-miR-363	CLIP-seq
MIRT1073229	hsa-miR-3646	CLIP-seq
MIRT2249846	hsa-miR-3662	CLIP-seq
MIRT1073232	hsa-miR-367	CLIP-seq
MIRT2249847	hsa-miR-3671	CLIP-seq
MIRT2249848	hsa-miR-3672	CLIP-seq
MIRT2249849	hsa-miR-3674	CLIP-seq
MIRT2249850	hsa-miR-3678-3p	CLIP-seq
MIRT2249851	hsa-miR-3681	CLIP-seq
MIRT2249852	hsa-miR-3685	CLIP-seq
MIRT1073233	hsa-miR-3686	CLIP-seq
MIRT2249853	hsa-miR-3688-3p	CLIP-seq
MIRT2249854	hsa-miR-379	CLIP-seq
MIRT1550246	hsa-miR-381	CLIP-seq
MIRT2249855	hsa-miR-384	CLIP-seq
MIRT1073234	hsa-miR-3919	CLIP-seq
MIRT2249856	hsa-miR-3920	CLIP-seq
MIRT1073235	hsa-miR-3925-5p	CLIP-seq
MIRT2249857	hsa-miR-3935	CLIP-seq
MIRT2249858	hsa-miR-3943	CLIP-seq
MIRT1073236	hsa-miR-3973	CLIP-seq
MIRT1073237	hsa-miR-3976	CLIP-seq
MIRT2018028	hsa-miR-410	CLIP-seq
MIRT1073239	hsa-miR-421	CLIP-seq
MIRT2249859	hsa-miR-4256	CLIP-seq
MIRT2249860	hsa-miR-4261	CLIP-seq
MIRT2249861	hsa-miR-4269	CLIP-seq
MIRT1073241	hsa-miR-4282	CLIP-seq
MIRT1073242	hsa-miR-4288	CLIP-seq
MIRT1073243	hsa-miR-431	CLIP-seq
MIRT2249862	hsa-miR-4311	CLIP-seq
MIRT2249863	hsa-miR-4319	CLIP-seq
MIRT2249864	hsa-miR-4320	CLIP-seq
MIRT2249865	hsa-miR-4325	CLIP-seq
MIRT2249866	hsa-miR-4327	CLIP-seq
MIRT2018031	hsa-miR-433	CLIP-seq
MIRT1073245	hsa-miR-4330	CLIP-seq
MIRT2249867	hsa-miR-4419a	CLIP-seq
MIRT2249868	hsa-miR-4446-5p	CLIP-seq
MIRT2249869	hsa-miR-4451	CLIP-seq
MIRT1073249	hsa-miR-4452	CLIP-seq
MIRT2249870	hsa-miR-4480	CLIP-seq
MIRT2249871	hsa-miR-4494	CLIP-seq
MIRT2249872	hsa-miR-4495	CLIP-seq
MIRT2249873	hsa-miR-4496	CLIP-seq
MIRT2018033	hsa-miR-4509	CLIP-seq
MIRT2018034	hsa-miR-450b-3p	CLIP-seq
MIRT2249874	hsa-miR-4510	CLIP-seq
MIRT1073250	hsa-miR-4514	CLIP-seq
MIRT2018035	hsa-miR-4645-3p	CLIP-seq
MIRT2249875	hsa-miR-4650-3p	CLIP-seq
MIRT2018036	hsa-miR-4662a-5p	CLIP-seq
MIRT2249876	hsa-miR-4666-3p	CLIP-seq
MIRT1073257	hsa-miR-4666-5p	CLIP-seq
MIRT2249877	hsa-miR-4680-3p	CLIP-seq
MIRT2249878	hsa-miR-4683	CLIP-seq
MIRT2018038	hsa-miR-4691-3p	CLIP-seq
MIRT1073259	hsa-miR-4692	CLIP-seq
MIRT2249879	hsa-miR-4694-3p	CLIP-seq
MIRT2249880	hsa-miR-4696	CLIP-seq
MIRT1073260	hsa-miR-4699-3p	CLIP-seq
MIRT1073261	hsa-miR-4701-5p	CLIP-seq
MIRT2249881	hsa-miR-4708-5p	CLIP-seq
MIRT1073262	hsa-miR-4709-5p	CLIP-seq
MIRT1073263	hsa-miR-4712-3p	CLIP-seq
MIRT2018040	hsa-miR-4713-3p	CLIP-seq
MIRT2249882	hsa-miR-4717-5p	CLIP-seq
MIRT1073264	hsa-miR-4721	CLIP-seq
MIRT2249883	hsa-miR-4724-3p	CLIP-seq
MIRT2249884	hsa-miR-4726-3p	CLIP-seq
MIRT2249885	hsa-miR-4731-3p	CLIP-seq
MIRT2249886	hsa-miR-4732-3p	CLIP-seq
MIRT2249887	hsa-miR-4732-5p	CLIP-seq
MIRT2249888	hsa-miR-4733-3p	CLIP-seq
MIRT1073266	hsa-miR-4734	CLIP-seq
MIRT2249889	hsa-miR-4739	CLIP-seq
MIRT2018042	hsa-miR-4740-3p	CLIP-seq
MIRT2249890	hsa-miR-4742-5p	CLIP-seq
MIRT2249891	hsa-miR-4744	CLIP-seq
MIRT2249892	hsa-miR-4755-5p	CLIP-seq
MIRT2249893	hsa-miR-4756-5p	CLIP-seq
MIRT1073268	hsa-miR-4760-5p	CLIP-seq
MIRT2249894	hsa-miR-4771	CLIP-seq
MIRT2249895	hsa-miR-4778-3p	CLIP-seq
MIRT2249896	hsa-miR-4782-5p	CLIP-seq
MIRT2249897	hsa-miR-4787-3p	CLIP-seq
MIRT2249898	hsa-miR-4789-3p	CLIP-seq
MIRT1073276	hsa-miR-4799-5p	CLIP-seq
MIRT2249899	hsa-miR-4801	CLIP-seq
MIRT2249900	hsa-miR-494	CLIP-seq
MIRT2249901	hsa-miR-495	CLIP-seq
MIRT2249902	hsa-miR-499a-5p	CLIP-seq
MIRT2249903	hsa-miR-508-5p	CLIP-seq
MIRT2249904	hsa-miR-5095	CLIP-seq
MIRT2249905	hsa-miR-513a-3p	CLIP-seq
MIRT2249906	hsa-miR-514	CLIP-seq
MIRT2249907	hsa-miR-514b-3p	CLIP-seq
MIRT2249908	hsa-miR-516b	CLIP-seq
MIRT1073277	hsa-miR-519a	CLIP-seq
MIRT1073278	hsa-miR-519b-3p	CLIP-seq
MIRT1073279	hsa-miR-519c-3p	CLIP-seq
MIRT1073280	hsa-miR-519d	CLIP-seq
MIRT1073281	hsa-miR-520a-5p	CLIP-seq
MIRT1073282	hsa-miR-520g	CLIP-seq
MIRT1073283	hsa-miR-520h	CLIP-seq
MIRT1073284	hsa-miR-525-5p	CLIP-seq
MIRT2018043	hsa-miR-532-3p	CLIP-seq
MIRT1073286	hsa-miR-548c-3p	CLIP-seq
MIRT2249909	hsa-miR-552	CLIP-seq
MIRT2249910	hsa-miR-556-3p	CLIP-seq
MIRT2249911	hsa-miR-556-5p	CLIP-seq
MIRT1073287	hsa-miR-568	CLIP-seq
MIRT1073288	hsa-miR-577	CLIP-seq
MIRT1073289	hsa-miR-579	CLIP-seq
MIRT1073290	hsa-miR-580	CLIP-seq
MIRT2249912	hsa-miR-583	CLIP-seq
MIRT1073291	hsa-miR-587	CLIP-seq
MIRT1073292	hsa-miR-588	CLIP-seq
MIRT1073293	hsa-miR-589	CLIP-seq
MIRT2249913	hsa-miR-590-3p	CLIP-seq
MIRT2249914	hsa-miR-607	CLIP-seq
MIRT1073295	hsa-miR-617	CLIP-seq
MIRT2249915	hsa-miR-618	CLIP-seq
MIRT1073296	hsa-miR-632	CLIP-seq
MIRT2249916	hsa-miR-638	CLIP-seq
MIRT1073297	hsa-miR-641	CLIP-seq
MIRT2249917	hsa-miR-642b	CLIP-seq
MIRT1073298	hsa-miR-643	CLIP-seq
MIRT1073301	hsa-miR-654-3p	CLIP-seq
MIRT2018045	hsa-miR-656	CLIP-seq
MIRT1073302	hsa-miR-663b	CLIP-seq
MIRT2018046	hsa-miR-665	CLIP-seq
MIRT1073303	hsa-miR-670	CLIP-seq
MIRT1073304	hsa-miR-7	CLIP-seq
MIRT1073305	hsa-miR-761	CLIP-seq
MIRT2018047	hsa-miR-769-3p	CLIP-seq
MIRT2249918	hsa-miR-875-3p	CLIP-seq
MIRT2018049	hsa-miR-924	CLIP-seq
MIRT1073306	hsa-miR-92a	CLIP-seq
MIRT1073307	hsa-miR-92b	CLIP-seq
MIRT1073308	hsa-miR-93	CLIP-seq
MIRT1073309	hsa-miR-935	CLIP-seq
MIRT1073184	hsa-miR-106a	CLIP-seq
MIRT1073185	hsa-miR-106b	CLIP-seq
MIRT2389480	hsa-miR-1273e	CLIP-seq
MIRT1073202	hsa-miR-17	CLIP-seq
MIRT1073205	hsa-miR-20a	CLIP-seq
MIRT1073206	hsa-miR-20b	CLIP-seq
MIRT1073207	hsa-miR-214	CLIP-seq
MIRT2389481	hsa-miR-3160-3p	CLIP-seq
MIRT1073225	hsa-miR-3617	CLIP-seq
MIRT1073227	hsa-miR-3619-5p	CLIP-seq
MIRT2389482	hsa-miR-4487	CLIP-seq
MIRT1073257	hsa-miR-4666-5p	CLIP-seq
MIRT1073280	hsa-miR-519d	CLIP-seq
MIRT2249911	hsa-miR-556-5p	CLIP-seq
MIRT2389483	hsa-miR-558	CLIP-seq
MIRT1073297	hsa-miR-641	CLIP-seq
MIRT1073303	hsa-miR-670	CLIP-seq
MIRT1073304	hsa-miR-7	CLIP-seq
MIRT1073305	hsa-miR-761	CLIP-seq
MIRT1073308	hsa-miR-93	CLIP-seq
MIRT1073184	hsa-miR-106a	CLIP-seq
MIRT1073185	hsa-miR-106b	CLIP-seq
MIRT1073202	hsa-miR-17	CLIP-seq
MIRT1073205	hsa-miR-20a	CLIP-seq
MIRT1073206	hsa-miR-20b	CLIP-seq
MIRT1073236	hsa-miR-3973	CLIP-seq
MIRT1073277	hsa-miR-519a	CLIP-seq
MIRT1073278	hsa-miR-519b-3p	CLIP-seq
MIRT1073279	hsa-miR-519c-3p	CLIP-seq
MIRT1073280	hsa-miR-519d	CLIP-seq
MIRT1073282	hsa-miR-520g	CLIP-seq
MIRT1073283	hsa-miR-520h	CLIP-seq
MIRT1073308	hsa-miR-93	CLIP-seq
MIRT1073309	hsa-miR-935	CLIP-seq
MIRT2451976	hsa-miR-1323	CLIP-seq
MIRT2249849	hsa-miR-3674	CLIP-seq
MIRT2249881	hsa-miR-4708-5p	CLIP-seq
MIRT2249887	hsa-miR-4732-5p	CLIP-seq
MIRT2451977	hsa-miR-548o	CLIP-seq
MIRT2018044	hsa-miR-606	CLIP-seq
MIRT2553318	hsa-miR-1	CLIP-seq
MIRT1073186	hsa-miR-1179	CLIP-seq
MIRT2553319	hsa-miR-1207-3p	CLIP-seq
MIRT2553320	hsa-miR-124	CLIP-seq
MIRT2249821	hsa-miR-1246	CLIP-seq
MIRT1073192	hsa-miR-1255a	CLIP-seq
MIRT1073193	hsa-miR-1255b	CLIP-seq
MIRT2249822	hsa-miR-125a-5p	CLIP-seq
MIRT2249823	hsa-miR-125b	CLIP-seq
MIRT1073195	hsa-miR-1265	CLIP-seq
MIRT1073196	hsa-miR-1266	CLIP-seq
MIRT2389480	hsa-miR-1273e	CLIP-seq
MIRT2249824	hsa-miR-1276	CLIP-seq
MIRT2553321	hsa-miR-1294	CLIP-seq
MIRT2249825	hsa-miR-1299	CLIP-seq
MIRT2249826	hsa-miR-1321	CLIP-seq
MIRT2451976	hsa-miR-1323	CLIP-seq
MIRT2553322	hsa-miR-136	CLIP-seq
MIRT1073199	hsa-miR-146a	CLIP-seq
MIRT1073200	hsa-miR-146b-5p	CLIP-seq
MIRT2553323	hsa-miR-1470	CLIP-seq
MIRT2249829	hsa-miR-1915	CLIP-seq
MIRT2553324	hsa-miR-194	CLIP-seq
MIRT2553325	hsa-miR-19a	CLIP-seq
MIRT2553326	hsa-miR-19b	CLIP-seq
MIRT2018024	hsa-miR-2053	CLIP-seq
MIRT2553327	hsa-miR-2054	CLIP-seq
MIRT2553328	hsa-miR-206	CLIP-seq
MIRT1073207	hsa-miR-214	CLIP-seq
MIRT2553329	hsa-miR-216a	CLIP-seq
MIRT2018025	hsa-miR-216b	CLIP-seq
MIRT2553330	hsa-miR-2278	CLIP-seq
MIRT2249830	hsa-miR-2355-5p	CLIP-seq
MIRT1073208	hsa-miR-2392	CLIP-seq
MIRT2553331	hsa-miR-2467-5p	CLIP-seq
MIRT1550245	hsa-miR-300	CLIP-seq
MIRT2553332	hsa-miR-302f	CLIP-seq
MIRT2249833	hsa-miR-3140-5p	CLIP-seq
MIRT2249834	hsa-miR-3145-3p	CLIP-seq
MIRT2249836	hsa-miR-3148	CLIP-seq
MIRT2553333	hsa-miR-3152-3p	CLIP-seq
MIRT2018026	hsa-miR-3152-5p	CLIP-seq
MIRT2389481	hsa-miR-3160-3p	CLIP-seq
MIRT2249840	hsa-miR-3162-5p	CLIP-seq
MIRT1073215	hsa-miR-3163	CLIP-seq
MIRT2018027	hsa-miR-3166	CLIP-seq
MIRT2249841	hsa-miR-3171	CLIP-seq
MIRT1073216	hsa-miR-3180-5p	CLIP-seq
MIRT2553334	hsa-miR-3188	CLIP-seq
MIRT2553335	hsa-miR-3190	CLIP-seq
MIRT1073219	hsa-miR-338-5p	CLIP-seq
MIRT2553336	hsa-miR-339-5p	CLIP-seq
MIRT2249843	hsa-miR-345	CLIP-seq
MIRT1073221	hsa-miR-346	CLIP-seq
MIRT2249844	hsa-miR-3529	CLIP-seq
MIRT1073225	hsa-miR-3617	CLIP-seq
MIRT1073226	hsa-miR-3619-3p	CLIP-seq
MIRT1073227	hsa-miR-3619-5p	CLIP-seq
MIRT1073229	hsa-miR-3646	CLIP-seq
MIRT1073231	hsa-miR-3658	CLIP-seq
MIRT2553337	hsa-miR-3667-3p	CLIP-seq
MIRT2249847	hsa-miR-3671	CLIP-seq
MIRT2553338	hsa-miR-3673	CLIP-seq
MIRT2249849	hsa-miR-3674	CLIP-seq
MIRT2249850	hsa-miR-3678-3p	CLIP-seq
MIRT2249851	hsa-miR-3681	CLIP-seq
MIRT2553339	hsa-miR-3714	CLIP-seq
MIRT2249854	hsa-miR-379	CLIP-seq
MIRT1550246	hsa-miR-381	CLIP-seq
MIRT2553340	hsa-miR-383	CLIP-seq
MIRT2553341	hsa-miR-3909	CLIP-seq
MIRT2553342	hsa-miR-3910	CLIP-seq
MIRT1073234	hsa-miR-3919	CLIP-seq
MIRT2249857	hsa-miR-3935	CLIP-seq
MIRT2553343	hsa-miR-3975	CLIP-seq
MIRT1073237	hsa-miR-3976	CLIP-seq
MIRT2249859	hsa-miR-4256	CLIP-seq
MIRT1073241	hsa-miR-4282	CLIP-seq
MIRT1073242	hsa-miR-4288	CLIP-seq
MIRT2553344	hsa-miR-4289	CLIP-seq
MIRT1073243	hsa-miR-431	CLIP-seq
MIRT2249862	hsa-miR-4311	CLIP-seq
MIRT2249863	hsa-miR-4319	CLIP-seq
MIRT2249864	hsa-miR-4320	CLIP-seq
MIRT1073244	hsa-miR-4328	CLIP-seq
MIRT1073245	hsa-miR-4330	CLIP-seq
MIRT2553345	hsa-miR-4427	CLIP-seq
MIRT2249868	hsa-miR-4446-5p	CLIP-seq
MIRT2249869	hsa-miR-4451	CLIP-seq
MIRT1073249	hsa-miR-4452	CLIP-seq
MIRT2553346	hsa-miR-4468	CLIP-seq
MIRT2249870	hsa-miR-4480	CLIP-seq
MIRT2389482	hsa-miR-4487	CLIP-seq
MIRT2249871	hsa-miR-4494	CLIP-seq
MIRT2553347	hsa-miR-4503	CLIP-seq
MIRT2018033	hsa-miR-4509	CLIP-seq
MIRT1073250	hsa-miR-4514	CLIP-seq
MIRT1073251	hsa-miR-4518	CLIP-seq
MIRT1073252	hsa-miR-4520b-3p	CLIP-seq
MIRT2553348	hsa-miR-4528	CLIP-seq
MIRT1073253	hsa-miR-4529-3p	CLIP-seq
MIRT1073254	hsa-miR-4535	CLIP-seq
MIRT2553349	hsa-miR-4640-3p	CLIP-seq
MIRT2553350	hsa-miR-4641	CLIP-seq
MIRT2018035	hsa-miR-4645-3p	CLIP-seq
MIRT2249875	hsa-miR-4650-3p	CLIP-seq
MIRT1073256	hsa-miR-4662a-3p	CLIP-seq
MIRT2249876	hsa-miR-4666-3p	CLIP-seq
MIRT1073257	hsa-miR-4666-5p	CLIP-seq
MIRT2553351	hsa-miR-4667-3p	CLIP-seq
MIRT2553352	hsa-miR-4668-3p	CLIP-seq
MIRT2249877	hsa-miR-4680-3p	CLIP-seq
MIRT2249878	hsa-miR-4683	CLIP-seq
MIRT2018038	hsa-miR-4691-3p	CLIP-seq
MIRT1073259	hsa-miR-4692	CLIP-seq
MIRT2249879	hsa-miR-4694-3p	CLIP-seq
MIRT2249880	hsa-miR-4696	CLIP-seq
MIRT1073261	hsa-miR-4701-5p	CLIP-seq
MIRT2249881	hsa-miR-4708-5p	CLIP-seq
MIRT2249882	hsa-miR-4717-5p	CLIP-seq
MIRT2249883	hsa-miR-4724-3p	CLIP-seq
MIRT2249884	hsa-miR-4726-3p	CLIP-seq
MIRT1073265	hsa-miR-4729	CLIP-seq
MIRT2249886	hsa-miR-4732-3p	CLIP-seq
MIRT2249887	hsa-miR-4732-5p	CLIP-seq
MIRT1073266	hsa-miR-4734	CLIP-seq
MIRT2249889	hsa-miR-4739	CLIP-seq
MIRT2249891	hsa-miR-4744	CLIP-seq
MIRT2249892	hsa-miR-4755-5p	CLIP-seq
MIRT2249893	hsa-miR-4756-5p	CLIP-seq
MIRT2553353	hsa-miR-4760-3p	CLIP-seq
MIRT2553354	hsa-miR-4762-3p	CLIP-seq
MIRT2249894	hsa-miR-4771	CLIP-seq
MIRT2553355	hsa-miR-4772-5p	CLIP-seq
MIRT1073272	hsa-miR-4776-5p	CLIP-seq
MIRT2249895	hsa-miR-4778-3p	CLIP-seq
MIRT2249896	hsa-miR-4782-5p	CLIP-seq
MIRT2249898	hsa-miR-4789-3p	CLIP-seq
MIRT2553356	hsa-miR-4795-3p	CLIP-seq
MIRT2249900	hsa-miR-494	CLIP-seq
MIRT2553357	hsa-miR-496	CLIP-seq
MIRT2249902	hsa-miR-499a-5p	CLIP-seq
MIRT2553358	hsa-miR-506	CLIP-seq
MIRT2553359	hsa-miR-512-5p	CLIP-seq
MIRT2249905	hsa-miR-513a-3p	CLIP-seq
MIRT2249908	hsa-miR-516b	CLIP-seq
MIRT2553360	hsa-miR-518a-5p	CLIP-seq
MIRT1073281	hsa-miR-520a-5p	CLIP-seq
MIRT1073284	hsa-miR-525-5p	CLIP-seq
MIRT2553361	hsa-miR-527	CLIP-seq
MIRT2553362	hsa-miR-548a-5p	CLIP-seq
MIRT2553363	hsa-miR-548ab	CLIP-seq
MIRT2553364	hsa-miR-548ak	CLIP-seq
MIRT2553365	hsa-miR-548b-5p	CLIP-seq
MIRT1073286	hsa-miR-548c-3p	CLIP-seq
MIRT2553366	hsa-miR-548c-5p	CLIP-seq
MIRT2553367	hsa-miR-548d-5p	CLIP-seq
MIRT2553368	hsa-miR-548h	CLIP-seq
MIRT2553369	hsa-miR-548i	CLIP-seq
MIRT2553370	hsa-miR-548j	CLIP-seq
MIRT2553371	hsa-miR-548m	CLIP-seq
MIRT2553372	hsa-miR-548n	CLIP-seq
MIRT2451977	hsa-miR-548o	CLIP-seq
MIRT2553373	hsa-miR-548t	CLIP-seq
MIRT2553374	hsa-miR-548w	CLIP-seq
MIRT2553375	hsa-miR-548y	CLIP-seq
MIRT2249911	hsa-miR-556-5p	CLIP-seq
MIRT2389483	hsa-miR-558	CLIP-seq
MIRT2553376	hsa-miR-559	CLIP-seq
MIRT2553377	hsa-miR-570	CLIP-seq
MIRT2553378	hsa-miR-576-3p	CLIP-seq
MIRT1073289	hsa-miR-579	CLIP-seq
MIRT2249912	hsa-miR-583	CLIP-seq
MIRT1073291	hsa-miR-587	CLIP-seq
MIRT1073292	hsa-miR-588	CLIP-seq
MIRT1073293	hsa-miR-589	CLIP-seq
MIRT2249913	hsa-miR-590-3p	CLIP-seq
MIRT1073294	hsa-miR-599	CLIP-seq
MIRT2018044	hsa-miR-606	CLIP-seq
MIRT2249914	hsa-miR-607	CLIP-seq
MIRT2553379	hsa-miR-610	CLIP-seq
MIRT2553380	hsa-miR-613	CLIP-seq
MIRT1073295	hsa-miR-617	CLIP-seq
MIRT2249915	hsa-miR-618	CLIP-seq
MIRT2553381	hsa-miR-626	CLIP-seq
MIRT2553382	hsa-miR-627	CLIP-seq
MIRT1073296	hsa-miR-632	CLIP-seq
MIRT1073297	hsa-miR-641	CLIP-seq
MIRT2553383	hsa-miR-642a	CLIP-seq
MIRT2249917	hsa-miR-642b	CLIP-seq
MIRT1073300	hsa-miR-651	CLIP-seq
MIRT1073301	hsa-miR-654-3p	CLIP-seq
MIRT1073302	hsa-miR-663b	CLIP-seq
MIRT2553384	hsa-miR-664	CLIP-seq
MIRT2018046	hsa-miR-665	CLIP-seq
MIRT1073303	hsa-miR-670	CLIP-seq
MIRT1073304	hsa-miR-7	CLIP-seq
MIRT1073305	hsa-miR-761	CLIP-seq
MIRT2553385	hsa-miR-802	CLIP-seq
MIRT2018049	hsa-miR-924	CLIP-seq
MIRT2553318	hsa-miR-1	CLIP-seq
MIRT1073186	hsa-miR-1179	CLIP-seq
MIRT2553319	hsa-miR-1207-3p	CLIP-seq
MIRT2553320	hsa-miR-124	CLIP-seq
MIRT2249821	hsa-miR-1246	CLIP-seq
MIRT1073192	hsa-miR-1255a	CLIP-seq
MIRT1073193	hsa-miR-1255b	CLIP-seq
MIRT2249822	hsa-miR-125a-5p	CLIP-seq
MIRT2249823	hsa-miR-125b	CLIP-seq
MIRT1073195	hsa-miR-1265	CLIP-seq
MIRT1073196	hsa-miR-1266	CLIP-seq
MIRT2389480	hsa-miR-1273e	CLIP-seq
MIRT2249824	hsa-miR-1276	CLIP-seq
MIRT2553321	hsa-miR-1294	CLIP-seq
MIRT2249825	hsa-miR-1299	CLIP-seq
MIRT2249826	hsa-miR-1321	CLIP-seq
MIRT2451976	hsa-miR-1323	CLIP-seq
MIRT2553322	hsa-miR-136	CLIP-seq
MIRT1073199	hsa-miR-146a	CLIP-seq
MIRT1073200	hsa-miR-146b-5p	CLIP-seq
MIRT2553323	hsa-miR-1470	CLIP-seq
MIRT2249829	hsa-miR-1915	CLIP-seq
MIRT2553324	hsa-miR-194	CLIP-seq
MIRT2553325	hsa-miR-19a	CLIP-seq
MIRT2553326	hsa-miR-19b	CLIP-seq
MIRT2018024	hsa-miR-2053	CLIP-seq
MIRT2553327	hsa-miR-2054	CLIP-seq
MIRT2553328	hsa-miR-206	CLIP-seq
MIRT1073207	hsa-miR-214	CLIP-seq
MIRT2553329	hsa-miR-216a	CLIP-seq
MIRT2018025	hsa-miR-216b	CLIP-seq
MIRT2553330	hsa-miR-2278	CLIP-seq
MIRT2249830	hsa-miR-2355-5p	CLIP-seq
MIRT1073208	hsa-miR-2392	CLIP-seq
MIRT2553331	hsa-miR-2467-5p	CLIP-seq
MIRT1550245	hsa-miR-300	CLIP-seq
MIRT2249833	hsa-miR-3140-5p	CLIP-seq
MIRT2249836	hsa-miR-3148	CLIP-seq
MIRT2553333	hsa-miR-3152-3p	CLIP-seq
MIRT2018026	hsa-miR-3152-5p	CLIP-seq
MIRT2389481	hsa-miR-3160-3p	CLIP-seq
MIRT2249840	hsa-miR-3162-5p	CLIP-seq
MIRT1073215	hsa-miR-3163	CLIP-seq
MIRT2018027	hsa-miR-3166	CLIP-seq
MIRT2249841	hsa-miR-3171	CLIP-seq
MIRT2553334	hsa-miR-3188	CLIP-seq
MIRT2553335	hsa-miR-3190	CLIP-seq
MIRT2553336	hsa-miR-339-5p	CLIP-seq
MIRT2249843	hsa-miR-345	CLIP-seq
MIRT1073225	hsa-miR-3617	CLIP-seq
MIRT1073227	hsa-miR-3619-5p	CLIP-seq
MIRT1073229	hsa-miR-3646	CLIP-seq
MIRT2553337	hsa-miR-3667-3p	CLIP-seq
MIRT2249847	hsa-miR-3671	CLIP-seq
MIRT2553338	hsa-miR-3673	CLIP-seq
MIRT2249849	hsa-miR-3674	CLIP-seq
MIRT2249850	hsa-miR-3678-3p	CLIP-seq
MIRT2249851	hsa-miR-3681	CLIP-seq
MIRT2553339	hsa-miR-3714	CLIP-seq
MIRT1550246	hsa-miR-381	CLIP-seq
MIRT2553340	hsa-miR-383	CLIP-seq
MIRT2553341	hsa-miR-3909	CLIP-seq
MIRT2553342	hsa-miR-3910	CLIP-seq
MIRT1073234	hsa-miR-3919	CLIP-seq
MIRT2553343	hsa-miR-3975	CLIP-seq
MIRT1073237	hsa-miR-3976	CLIP-seq
MIRT2249859	hsa-miR-4256	CLIP-seq
MIRT2249860	hsa-miR-4261	CLIP-seq
MIRT1073241	hsa-miR-4282	CLIP-seq
MIRT2553344	hsa-miR-4289	CLIP-seq
MIRT1073243	hsa-miR-431	CLIP-seq
MIRT2249862	hsa-miR-4311	CLIP-seq
MIRT2249863	hsa-miR-4319	CLIP-seq
MIRT2249864	hsa-miR-4320	CLIP-seq
MIRT1073244	hsa-miR-4328	CLIP-seq
MIRT1073245	hsa-miR-4330	CLIP-seq
MIRT2249868	hsa-miR-4446-5p	CLIP-seq
MIRT1073249	hsa-miR-4452	CLIP-seq
MIRT2553346	hsa-miR-4468	CLIP-seq
MIRT2389482	hsa-miR-4487	CLIP-seq
MIRT2249871	hsa-miR-4494	CLIP-seq
MIRT2553347	hsa-miR-4503	CLIP-seq
MIRT2018033	hsa-miR-4509	CLIP-seq
MIRT1073250	hsa-miR-4514	CLIP-seq
MIRT1073251	hsa-miR-4518	CLIP-seq
MIRT2553348	hsa-miR-4528	CLIP-seq
MIRT2553349	hsa-miR-4640-3p	CLIP-seq
MIRT2553350	hsa-miR-4641	CLIP-seq
MIRT2018035	hsa-miR-4645-3p	CLIP-seq
MIRT1073256	hsa-miR-4662a-3p	CLIP-seq
MIRT2249876	hsa-miR-4666-3p	CLIP-seq
MIRT1073257	hsa-miR-4666-5p	CLIP-seq
MIRT2553351	hsa-miR-4667-3p	CLIP-seq
MIRT2553352	hsa-miR-4668-3p	CLIP-seq
MIRT2249877	hsa-miR-4680-3p	CLIP-seq
MIRT2249878	hsa-miR-4683	CLIP-seq
MIRT2018038	hsa-miR-4691-3p	CLIP-seq
MIRT1073259	hsa-miR-4692	CLIP-seq
MIRT2249879	hsa-miR-4694-3p	CLIP-seq
MIRT2249880	hsa-miR-4696	CLIP-seq
MIRT1073261	hsa-miR-4701-5p	CLIP-seq
MIRT2249881	hsa-miR-4708-5p	CLIP-seq
MIRT2249884	hsa-miR-4726-3p	CLIP-seq
MIRT1073265	hsa-miR-4729	CLIP-seq
MIRT2249886	hsa-miR-4732-3p	CLIP-seq
MIRT2249887	hsa-miR-4732-5p	CLIP-seq
MIRT2249889	hsa-miR-4739	CLIP-seq
MIRT2249891	hsa-miR-4744	CLIP-seq
MIRT2249892	hsa-miR-4755-5p	CLIP-seq
MIRT2249893	hsa-miR-4756-5p	CLIP-seq
MIRT2553353	hsa-miR-4760-3p	CLIP-seq
MIRT2553354	hsa-miR-4762-3p	CLIP-seq
MIRT2249894	hsa-miR-4771	CLIP-seq
MIRT2553355	hsa-miR-4772-5p	CLIP-seq
MIRT2249896	hsa-miR-4782-5p	CLIP-seq
MIRT2249898	hsa-miR-4789-3p	CLIP-seq
MIRT2553356	hsa-miR-4795-3p	CLIP-seq
MIRT2249900	hsa-miR-494	CLIP-seq
MIRT2553357	hsa-miR-496	CLIP-seq
MIRT2249902	hsa-miR-499a-5p	CLIP-seq
MIRT2553358	hsa-miR-506	CLIP-seq
MIRT2553359	hsa-miR-512-5p	CLIP-seq
MIRT2249905	hsa-miR-513a-3p	CLIP-seq
MIRT2249908	hsa-miR-516b	CLIP-seq
MIRT2553360	hsa-miR-518a-5p	CLIP-seq
MIRT2553361	hsa-miR-527	CLIP-seq
MIRT2553362	hsa-miR-548a-5p	CLIP-seq
MIRT2553363	hsa-miR-548ab	CLIP-seq
MIRT2553364	hsa-miR-548ak	CLIP-seq
MIRT2553365	hsa-miR-548b-5p	CLIP-seq
MIRT2553366	hsa-miR-548c-5p	CLIP-seq
MIRT2553367	hsa-miR-548d-5p	CLIP-seq
MIRT2553368	hsa-miR-548h	CLIP-seq
MIRT2553369	hsa-miR-548i	CLIP-seq
MIRT2553370	hsa-miR-548j	CLIP-seq
MIRT2553372	hsa-miR-548n	CLIP-seq
MIRT2451977	hsa-miR-548o	CLIP-seq
MIRT2553373	hsa-miR-548t	CLIP-seq
MIRT2553374	hsa-miR-548w	CLIP-seq
MIRT2553375	hsa-miR-548y	CLIP-seq
MIRT2249911	hsa-miR-556-5p	CLIP-seq
MIRT2389483	hsa-miR-558	CLIP-seq
MIRT2553376	hsa-miR-559	CLIP-seq
MIRT2553378	hsa-miR-576-3p	CLIP-seq
MIRT1073289	hsa-miR-579	CLIP-seq
MIRT2249912	hsa-miR-583	CLIP-seq
MIRT1073292	hsa-miR-588	CLIP-seq
MIRT1073293	hsa-miR-589	CLIP-seq
MIRT2249913	hsa-miR-590-3p	CLIP-seq
MIRT1073294	hsa-miR-599	CLIP-seq
MIRT2018044	hsa-miR-606	CLIP-seq
MIRT2249914	hsa-miR-607	CLIP-seq
MIRT2553379	hsa-miR-610	CLIP-seq
MIRT2553380	hsa-miR-613	CLIP-seq
MIRT1073295	hsa-miR-617	CLIP-seq
MIRT2249915	hsa-miR-618	CLIP-seq
MIRT2553381	hsa-miR-626	CLIP-seq
MIRT2553382	hsa-miR-627	CLIP-seq
MIRT1073297	hsa-miR-641	CLIP-seq
MIRT2553383	hsa-miR-642a	CLIP-seq
MIRT2249917	hsa-miR-642b	CLIP-seq
MIRT1073300	hsa-miR-651	CLIP-seq
MIRT1073302	hsa-miR-663b	CLIP-seq
MIRT2553384	hsa-miR-664	CLIP-seq
MIRT2018046	hsa-miR-665	CLIP-seq
MIRT1073303	hsa-miR-670	CLIP-seq
MIRT1073304	hsa-miR-7	CLIP-seq
MIRT1073305	hsa-miR-761	CLIP-seq
MIRT2553385	hsa-miR-802	CLIP-seq
MIRT2249918	hsa-miR-875-3p	CLIP-seq
MIRT2018049	hsa-miR-924	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	IEA
GO:0001558	Process	Regulation of cell growth	NAS	9462742
GO:0002376	Process	Immune system process	IEA
GO:0002669	Process	Positive regulation of T cell anergy	IEA
GO:0002683	Process	Negative regulation of immune system process	IEA
GO:0002684	Process	Positive regulation of immune system process	IEA
GO:0002753	Process	Cytoplasmic pattern recognition receptor signaling pathway	IDA	16125763, 31390091
GO:0002870	Process	T cell anergy	IEA
GO:0004842	Function	Ubiquitin-protein transferase activity	EXP	34999730
GO:0004842	Function	Ubiquitin-protein transferase activity	IEA
GO:0005515	Function	Protein binding	IPI	9647693, 15051726, 15678106, 16888620, 16908849, 17028573, 17174309, 17592138, 18334649, 19580544, 20068034, 20392206, 20491914, 20676133, 20818436, 20858735, 22009753, 22057290, 22810586, 23146885, 23236378, 24790097, 25436413, 26854353, 28514442, 32814053, 33961781, 34927784, 3710
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IC	27736772
GO:0005768	Component	Endosome	IEA
GO:0005769	Component	Early endosome	IDA	24790097
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	34927784
GO:0005886	Component	Plasma membrane	IDA	14602072
GO:0005886	Component	Plasma membrane	IEA
GO:0005938	Component	Cell cortex	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IDA	15678106
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IMP	22009753, 25518932
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	NAS	9462742
GO:0006513	Process	Protein monoubiquitination	IDA	34927784
GO:0006915	Process	Apoptotic process	IEA
GO:0006954	Process	Inflammatory response	NAS	9462742
GO:0006979	Process	Response to oxidative stress	IDA	17603038
GO:0009896	Process	Positive regulation of catabolic process	IEA
GO:0010008	Component	Endosome membrane	IEA
GO:0010468	Process	Regulation of gene expression	IEA
GO:0010604	Process	Positive regulation of macromolecule metabolic process	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016567	Process	Protein ubiquitination	IDA	17592138, 25631046
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016567	Process	Protein ubiquitination	IMP	24790097
GO:0016740	Function	Transferase activity	IEA
GO:0016874	Function	Ligase activity	IEA
GO:0019787	Function	Ubiquitin-like protein transferase activity	TAS
GO:0030163	Process	Protein catabolic process	IEA
GO:0031410	Component	Cytoplasmic vesicle	IDA	22009753
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031623	Process	Receptor internalization	IMP	34927784
GO:0031901	Component	Early endosome membrane	IEA
GO:0032480	Process	Negative regulation of type I interferon production	TAS
GO:0032991	Component	Protein-containing complex	IDA	24790097
GO:0034450	Function	Ubiquitin-ubiquitin ligase activity	IDA	29378950
GO:0035519	Process	Protein K29-linked ubiquitination	IDA	17028573, 18628966
GO:0035739	Process	CD4-positive, alpha-beta T cell proliferation	IEA
GO:0035872	Process	Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	TAS
GO:0038160	Process	CXCL12-activated CXCR4 signaling pathway	IDA	28978524
GO:0039532	Process	Negative regulation of cytoplasmic pattern recognition receptor signaling pathway	IDA	27736772
GO:0043021	Function	Ribonucleoprotein complex binding	IPI	19881509
GO:0043066	Process	Negative regulation of apoptotic process	IMP	20068034
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IEA
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	ISS
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IBA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	29378950
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	22009753
GO:0044389	Function	Ubiquitin-like protein ligase binding	IPI	24790097
GO:0045087	Process	Innate immune response	IEA
GO:0045236	Function	CXCR chemokine receptor binding	IPI	19116316
GO:0045732	Process	Positive regulation of protein catabolic process	IEA
GO:0046329	Process	Negative regulation of JNK cascade	IEA
GO:0046329	Process	Negative regulation of JNK cascade	ISS
GO:0046718	Process	Symbiont entry into host cell	IEA
GO:0046718	Process	Symbiont entry into host cell	TAS	12450395
GO:0050687	Process	Negative regulation of defense response to virus	IEA
GO:0050687	Process	Negative regulation of defense response to virus	IMP	19881509
GO:0051241	Process	Negative regulation of multicellular organismal process	IEA
GO:0051607	Process	Defense response to virus	IEA
GO:0051865	Process	Protein autoubiquitination	IMP	24790097
GO:0060544	Process	Regulation of necroptotic process	TAS
GO:0061630	Function	Ubiquitin protein ligase activity	IBA
GO:0061630	Function	Ubiquitin protein ligase activity	IDA	15678106, 17592138, 27736772, 29378950, 34927784
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IMP	15051726, 22009753, 24790097
GO:0061630	Function	Ubiquitin protein ligase activity	NAS	10940313
GO:0061630	Function	Ubiquitin protein ligase activity	TAS
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0070534	Process	Protein K63-linked ubiquitination	IDA	18718448, 19592251, 29378950
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	19881509, 27736772, 30328013
GO:0070936	Process	Protein K48-linked ubiquitination	IEA
GO:0071944	Component	Cell periphery	IEA
GO:0090085	Process	Regulation of protein deubiquitination	IEA
GO:0090085	Process	Regulation of protein deubiquitination	ISS
GO:0141198	Process	Protein branched polyubiquitination	IDA	29378950
GO:1902036	Process	Regulation of hematopoietic stem cell differentiation	TAS
GO:1902532	Process	Negative regulation of intracellular signal transduction	IEA
GO:1990763	Function	Arrestin family protein binding	IPI	23886940
GO:2000562	Process	Negative regulation of CD4-positive, alpha-beta T cell proliferation	IEA
GO:2000646	Process	Positive regulation of receptor catabolic process	IMP	24790097

Other IDs

• MIM: 606409
• HGNC: 13890
• e!Ensembl: ENSG00000078747

Protein

• UniProt ID: Q96J02
• Protein name: E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)
• Protein function: Acts as an Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:11046148, PubMed:14602072, PubM
• PDB: 2DMV, 2KYK, 2NQ3, 2P4R, 2YSF, 3TUG, 4ROF, 5C7M, 5CQ2, 5DWS, 5DZD, 5SXP
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00168	C2	18 → 116	C2 domain	Domain
  PF00397	WW	328 → 357	WW domain	Domain
  PF00397	WW	360 → 389	WW domain	Domain
  PF00397	WW	440 → 469	WW domain	Domain
  PF00397	WW	480 → 509	WW domain	Domain
  PF00632	HECT	598 → 903	HECT-domain (ubiquitin-transferase)	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed.
• Sequence:

  MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
  NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
  QLGGDKEPTETIGDLSICLDGLQLESEVVTNGETTCSENGVSLCLPRLECNSAISAHCNL
  CLPGLSDSPISASRVAGFTGASQNDDGSRSKDETRVSTNGSDDPEDAGAGENRRVSGNNS
  PSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNTSEG
  ATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPL
  PPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIY
  GNQDLFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPL
  PEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQ
  QLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLL
  SHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFS
  LPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEILGEIKSHDL
  KPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEV
  LLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVG
  GFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGF
  GQE

• Sequence length: 903

Pathways

KEGG:

Ubiquitin mediated proteolysis
Endocytosis
Notch signaling pathway
TNF signaling pathway
Non-alcoholic fatty liver disease

Reactome:

Downregulation of ERBB4 signaling
NOD1/2 Signaling Pathway
Activated NOTCH1 Transmits Signal to the Nucleus
Degradation of GLI1 by the proteasome
Hedgehog 'on' state
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Negative regulators of DDX58/IFIH1 signaling
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Syndromic multisystem autoimmune disease due to ITCH deficiency	Pathogenic; Likely pathogenic	rs1568998827, rs2146507793, rs587776592, rs2515695390, rs2515940072, rs2515819804, rs2515548244, rs2515866863, rs2515520453, rs2038571383, rs1988702062, rs1988672290, rs1983332740, rs1381447036	RCV001329453 RCV001953515 RCV000004641 RCV002971446 RCV003024828 RCV003039422 RCV003503350 RCV003613201 RCV003613174 RCV003989038 RCV001194604 RCV001196138 RCV001255428 RCV001255429

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Acute myeloid leukemia	Likely benign; Benign	rs775124189, rs773671382, rs141828786	RCV005925788 RCV005896893 RCV005896886
Cervical cancer	Benign; Likely benign	rs141828786	RCV005896888
Colorectal cancer	Conflicting classifications of pathogenicity	rs759646195	RCV005869721
Familial cancer of breast	Conflicting classifications of pathogenicity	rs759646195	RCV005869720
Gastric cancer	Benign; Likely benign	rs141828786	RCV005896890
Hepatocellular carcinoma	Benign	rs6059861	RCV005932737
ITCH-related disorder	Likely benign; Uncertain significance; Benign; Conflicting classifications of pathogenicity	rs763708482, rs950440320, rs761575378, rs371860516, rs373086001, rs868361524, rs374135990, rs1322957108, rs1408067966, rs149046008, rs2516020137, rs141828786, rs149625278, rs144293716, rs370123057	RCV003920920 RCV003956010 RCV003900718 RCV003965981 RCV003401904 RCV003958671 RCV003968867 RCV003394385 RCV003949081 RCV003894557 RCV003899832 RCV003925672 RCV003953166 RCV004756091 RCV003970699
Malignant tumor of esophagus	Benign; Likely benign	rs141828786	RCV005896887
Melanoma	Benign; Likely benign	rs141828786	RCV005896892
Sarcoma	Benign; Likely benign	rs141828786	RCV005896889
See cases	Uncertain significance	rs879012592	RCV002252572
Thyroid cancer, nonmedullary, 1	Benign; Likely benign	rs141828786	RCV005896891

Associations from Text Mining
Disease Name	Relationship Type	References
Adenocarcinoma	Associate	34818353
Adenocarcinoma of Lung	Associate	37762133
Arthritis	Associate	33894394
Autoimmune Diseases	Associate	20170897
Autoimmune Diseases of the Nervous System	Associate	33894394
Behcet Syndrome	Associate	26890122
Breast Neoplasms	Associate	34927784
Carcinoma Hepatocellular	Associate	28636993, 34531437, 34841685, 36114756
Carcinoma Hepatocellular	Inhibit	36442661
Carcinoma Ovarian Epithelial	Associate	30556849
Carcinoma Renal Cell	Inhibit	33969128
Colitis Ulcerative	Inhibit	28842689
Colorectal Neoplasms	Associate	32774060
Congenital Abnormalities	Associate	20170897
Diabetes Mellitus Type 1	Associate	33894394
Drug Related Side Effects and Adverse Reactions	Associate	36442661
Esophageal Neoplasms	Associate	23874846
Glioblastoma	Associate	20484045
Hypoxia	Associate	35811256
Hypoxia Brain	Inhibit	35811256
Immunologic Deficiency Syndromes	Inhibit	20170897
Immunologic Deficiency Syndromes	Associate	33894394
Inflammation	Associate	29212706, 35811256
Inflammatory Bowel Diseases	Associate	33894394
Intervertebral Disc Degeneration	Associate	34015763
Lactic Acidosis Congenital Infantile Due To LAD Deficiency	Associate	20170897
Leukemia Lymphocytic Chronic B Cell	Associate	19096009
Lung Neoplasms	Associate	26219257, 27642589, 30078010
Lung Neoplasms	Inhibit	35811256
Melanocytic nevus syndrome congenital	Associate	34912899
Melanoma	Inhibit	31403357
Mixed Tumor Malignant	Associate	34531437
Multiple Sclerosis	Associate	23039885
Neoplasm Metastasis	Inhibit	33499704, 33969128
Neoplasm Metastasis	Associate	34841685
Neoplasms	Associate	23319410, 23538446, 25267700, 27203743, 30078010, 31443721, 32774060
Neoplasms	Inhibit	27642589, 31403357, 33969128
Neuroblastoma	Associate	22009753, 37957138
Pancreatic Neoplasms	Associate	25267700
Papillary Thyroid Microcarcinoma	Associate	19016753
Primary Immunodeficiency Diseases	Associate	38644452
Renal Insufficiency	Associate	33894394
Stomach Neoplasms	Associate	30866608
Stomach Neoplasms	Inhibit	33499704
Thyroid Cancer Papillary	Stimulate	19016753
Thyroid Carcinoma Anaplastic	Associate	19016753
Thyroid Neoplasms	Associate	19016753
Thyroid Nodule	Associate	34531437
Uveitis	Associate	33894394