Gene Gene information from NCBI Gene database.
Entrez ID 83734
Gene name Autophagy related 10
Gene symbol ATG10
Synonyms (NCBI Gene)
APG10APG10Lpp12616
Chromosome 5
Chromosome location 5q14.1-q14.2
Summary Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modif
miRNA miRNA information provided by mirtarbase database.
626
miRTarBase ID miRNA Experiments Reference
MIRT021335 hsa-miR-9-5p Microarray 17612493
MIRT024684 hsa-miR-215-5p Microarray 19074876
MIRT025071 hsa-miR-181a-5p Microarray 17612493
MIRT026156 hsa-miR-192-5p Microarray 19074876
MIRT540702 hsa-miR-8485 HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
GO ID Ontology Definition Evidence Reference
GO:0000045 Process Autophagosome assembly IBA
GO:0000045 Process Autophagosome assembly IDA 23202584
GO:0000045 Process Autophagosome assembly IDA 16963840
GO:0000423 Process Mitophagy IBA
GO:0005515 Function Protein binding IPI 32296183, 32814053
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610800 20315 ENSG00000152348
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H0Y0
Protein name Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like)
Protein function E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugatio
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03987 Autophagy_act_C 11 207 Autophagocytosis associated protein, active-site domain Domain
Sequence
Sequence length 220
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Autophagy - other
Autophagy - animal
  Macroautophagy